Entry: PS50271

Forthcoming changes to the profile format
General information about the entry

Entry name [info] ZF_UBP
Accession [info] PS50271
Entry type [info] MATRIX
Date [info] OCT-2005 (CREATED); OCT-2013 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC50271
Associated ProRule [info] PRU00502

Name and characterization of the entry

Description [info] Zinc finger UBP-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=62;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=57;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.7795434; R2=0.0055944; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2593.06410; R2=19.35150; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=1452; N_SCORE=9.9; H_SCORE=25834; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=844; N_SCORE=6.5; H_SCORE=18926; MODE=1; TEXT='?';
/DEFAULT: M0=-16; D=-80; I=-80; B1=-200; E1=-200; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='W'; M= -9, 19,-44,-23,-29,-15,-23,-17, 37, -9,  2,-23,  2, 10,  1,  8,  5,-14, 90,-34;
/M: SY='K'; M=-30,-21,-28,-26,-17,  5, 15,  1, 36, -7,-14,-20, -2,  8, 31,-26, -3, 17,-52, -4;
/M: SY='C'; M=-29,143,-57,-58,-33,-37,-58,-54,-54,-46,-46,-32,-68,-61,-60,-29,-38,-31,-76,-57;
/I:         I=-22; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='S'; M= -6,  4,-10, 22, -5,-13, 14,-42,-10,-30, -3, -1,-20,  0,-38, 54,  1, -3,-54,  3;
/M: SY='V'; M=-24,-50, 27, 28,-45,-16,-40,  3, 15,-23,  6,  2,-45,  6,-13,  4, 11, 29,-59,-27;
/M: SY='C'; M=-35,133,-32,-41,-50,-24,-53,-53,-48,-48,-46,-38,-59,-52,-55, 17, 23,-42,-74,-55;
/M: SY='D'; M=-29,-37, 46,  5,-18, 30,  9,-43,-12, 20, -8, 11,-48, 33,-28, -8,-32,-44,-57,-40;
/I:         I=-18; MI=0; MD=-57; IM=0; DM=-57;
/M: SY='S'; M=-22, -7,-20, 13,-31, -9, 11,-25, -5, -2,-10, 18,-35,-32,-15, 45, 20,-15, 22, -4; D=-18;
/I:         I=-18; DM=-57;
/M: SY='W'; M=-27, 14,-16,  9,-22, -5, -7,-22,  0,-17,-25, 33,-13, -1, 17, -4, 35,-16, 57,-20;
/M: SY='E'; M=-25,-38,  3, 35,-33,  5, 17, -5, -2,-12,-37, 22, -5, -3,-11,  9, 16,  3,-59,-42;
/M: SY='N'; M=-16,-50, 24, 13,-54,-14, 48,-54,-20,-39,-23, 72, -2,  2,  5, 21,-23,-52,-66,-43;
/M: SY='L'; M=-39,-47,-51,-51,-28,-56,-47, 37,-49, 50,  5, 21,-21,-46,-51,-15,  0, 32,-56,-36;
/M: SY='W'; M=-49,-65,-36,-51, 18,-53, -3,-32,-43,-14, 20,-56,-57,-43, -1,-32,-51,-47,140, 68;
/M: SY='C'; M= 21, 41,-56,-50,-31,-52,-50, 33,-48, 37, 36,-49,-54,-45,-19,-15,-18, 27,-55,-38;
/M: SY='C'; M=-39,143,-52,-56,-50,-51,-54,-56,-51,-48,-47, 19,-68,-58,-58,-40,-38,-45,-79,-59;
/M: SY='L'; M=-28,-21,-60,-53,-15,-61,-46,  4,-52, 74, 23,-57,-59,-47,-26,-41,-22, -4,-50,-32;
/M: SY='T'; M=-26,-27,  5,  6,-43,-18, 14, 24,-15,-31,-32,-32,-45, 36,-39, 11, 44, 25,-58,-14;
/I:         I=-22; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='C'; M=-39,142, 13,-51,-50,-53,-55,-57,-52,-48,-48,-41,-66,-58,-59,-30,-38,-45,-79,-59;
/M: SY='G'; M=-27,-54,-19,-20,-23, 77,-23,-39,-27,-48,-38, -7, 17,-26,-30,  6,-40,-32,-50, -6;
/M: SY='H'; M=-15,-21,-37,-27, 16,-31, 69,-31, 33,-17, -3, 20,-48, 13,  0, 18,-27,-35, -9, 26;
/M: SY='Y'; M=-35,  3,-53,-51, 18,-57, 12, 34,-47,-11,-17,-32, -6,-32,-38,-11,-11, 51,-40, 56;
/M: SY='G'; M= -2,-50,-50,-53, 53, 58,-44,-35,-49, 13,-10,-23,-53,-48,-51,-21,-32,-14,-38, 22;
/M: SY='C'; M=-38,136,-51,-34,-52,-38,-50,-55,-45,-47,-45,-41,-62, 44,-50,-37,-14,-45,-72,-55;
/M: SY='G'; M=-24, 39,-23,-32,-21, 75,-49,-16,-37,-45,-46,-31,-25,-44,-41,  7, -5,-36, 32,-47;
/I:         I=-13; MD=-40;
/M: SY='R'; M=-48,-64,  9, -5,-42,-16,-37,-52,  3,-58,-49, -5,-55,-27, 84,-33,-16,-57,-14,-29; D=-13;
/I:         I=-13; MD=-40;
/M: SY='Y'; M=-11,-62,  6,-11, -8,  9,  1,-54,-15,-53,-30, -8,-24,-27,-11,  1,-13,-32, 10, 56; D=-13;
/I:         I=-13; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='P'; M=-29,-34,-13,-15,-52, 29,-16,-24,  8,-49,-34,-27, 47, 12,-17,-43,-37, -7,-64,-44; D=-13;
/I:         I=-13; DM=-40;
/M: SY='N'; M=-22,-56,-20,  5,-56,  7, 43,-59,  6,-41,-48, 62,-52, 19, -9, 11,-37,-53,-65,-14; D=-13;
/I:         I=-13; DM=-40;
/M: SY='S'; M= -8,-50, 10, 13,-56, 37,-37,-54, 11,-46,-28, 13,-43, 14,  2, 46, -5,-39,-58,-47;
/M: SY='H'; M=-47,-59, -8,-20,-44,-49,132,-59,-36,-46,-16,-23,  8,-27,-32,-37,-44,-46,-25,  1;
/I:         I=-24; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='A'; M= 72,-21,-47,-40,-11,-11,-46,  1,-40,-29, 12,-40,-46,-21,-17,  9,-31,-11,-52,-43;
/M: SY='Y'; M=-35,-51,-33,-14,  7,-46, 16,  4,  1, 35, -2,-28,-52,  8, 11,-20, 16,-10,-42, 44;
/M: SY='W'; M= -6,-24, -3, 33,-16,-27, -2,-16, 34,-12, -5,-26,-29, 21,  9,  0,  1,-12, 34,-27;
/M: SY='H'; M=-47,-59,-31,-31,-46,-49,139,-64,-36,-46,-32,-20,-48,-25,-30,-37,-46,-63,-81,-15;
/M: SY='Y'; M= 29,-11,-45,-45, 43, -4, 27,-41,-43,-34,-36,-23,-51,-39,-44, 35,-25,-31, 31, 64;
/M: SY='Q'; M=-35,-31,-10, 32,-21,-44, 23, -5, 24,  5,-13, 15,-46, 37, 26,-15,-25, -3,-55,-38;
/M: SY='E'; M= -3,-51,  9, 50,-38,-32,-13,-45, 18, -9,  0, 10,-42, 37,-23, 17,  1,-24,-57,-43;
/I:         I=-19; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='T'; M=-16,-46,  6, 20,-21,-43,-11,-34, 17,-32,-14,  5,-40,  0,-26, 22, 67,-23,-60,-42;
/M: SY='G'; M=-25,-18, 14, -5,-55, 40, 13,-56, 23,-33,-29, 37,-46, 27, 13, 18,-23,-52,-58,-45;
/I:         I=-24; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='H'; M=-47,-59,-32,-32,-22,-49,135,-61,-36,-45,-31,-22,-49,-26,-19,-37,-46,-61,-68, 23;
/M: SY='P'; M=-24, 49,-31,-38,-24,-31, 55,-24,-36,-20, -6,  6, 72,-23, 15,-22,-21,-42, 56, -5;
/M: SY='V'; M=-36, -1,-61,-56, 43,-61,-49, 25,-53, 38, 11,-40,-59,-53,-53,-49,-36, 50,-43, 20;
/M: SY='A'; M= 49,  7,-50,-46, 40,  6,-45,-11,-45,-34,-34,-42,-50,-44,-48, 13,-18, 21,-12, 25;
/M: SY='M'; M=-18,-48,-58,-29, -2,-60,-50, 40,-49, 34, 58,-53,-54,-18,-33,-47,-36, 47, -2,-32;
/M: SY='N'; M=-37,-52, 32, 19,-51,-18, -1,-39, 30,-29,-25, 55,-45, 15,-20, 23,-18,-26, 35,-42;
/M: SY='L'; M=-29, 14,-55,-51, 21,-55, -8,  8,-50, 51, 21,-35,-57,-37,-49,  8,-24,  6, -2, 39;
/M: SY='E'; M= -1,-27,  2, 25,-52, 25,  0,-34, 17,-29,-30,  4,-31,  8, 15, 23, 11,-40,-56,-25;
/M: SY='T'; M=-33, -5, 27,-10,-49,-36,-11,-47,-14,-50,-44, 33, 10,-32, -4, 29, 68,-41,-63,-11;
/M: SY='P'; M=-20,-12,-40, -9, -4, 22, -6, 19, -3, 15, -7,-21, 43, 33,-41,-11,-38,-31,-12,-27;
/M: SY='R'; M=-16,-51, -2, 13,-25,-30, -1,-45, 23,-14, -6, -7,-21, 24, 29, 18, 25,-37,-49, 24;
/M: SY='V'; M= -2,-23,-29,-36, 19,-31,-51, 23,-13, 15,  2,-46, 12,-46,-48,-16, 14, 46,-53,-34;
/I:         I=-15; MI=0; MD=-47; IM=0; DM=-47;
/M: SY='W'; M=-50,  2,-57,-54, 31,-54,-14,-30,-45,-35,-35,-30,-60,-44,-31,-49,-49,-45,124, 97;
/M: SY='C'; M=-37,125, 34,-31,-35,-49,-49,-19,-47,-45,-24, -1,-59,-49,-53,  9,-34,-12,-73,-52;
/M: SY='Y'; M=-49,-25,-53,-33, 64,-58,-27,-17,-47, 20,-24,-51,-60,  1,-44,-47,-43,-33,-17, 94;
/M: SY='P'; M= 19,-29, -4,  1,-47,-27,-29, -1, -7,-10, 24, -9, 61,  0, -9,  2,-22, -3,-56,-35;
/M: SY='C'; M=-31,119, 16, 30,-53,  4,-20,-57,-41,-45,-48,-23,-26,-14,-48,-15,-11,-48,-69,-54;
/M: SY='D'; M=-39,-56, 72, 40,-61,  5,-31,-47, -2,-57,-31, 34,-43, 27, -6, -5,-35,-55,-65,-48;
/M: SY='D'; M= -7,-27, 66, 25,-21,-25,-31,-48, -1,-36, -5, 14,-46,-29,  2,  2,-22,-23,-51, 37;
/M: SY='Y'; M=-20, 12, -9, 38, 31,-52,-31, -2,-24,-17, 35,-32,  2, -6,-40,-21,-28,-28,-16, 70;
/M: SY='V'; M=-24,-47,-58,-44,  1,-61,-55, 36,-35, 14, -8,-53,-56,-50,-18,-45,-17, 70,-11, -3;
/M: SY='H'; M=-32,-26, 10,  4,  6,-27, 66, -4, -2,  0,-33,  2, -8,-18, -8, -3,  0,-13, 26, 28;
/M: SY='D'; M=-35,-54, 62,  4,-14,-39, 28, -9,-31,  5,-21, 26,-18, -9, 20,  2,-28,-21,-61,-26;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 76 in 75 different sequences
Number of true positive hits 76 in 75 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] N_Hulo
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Feature key [info] ZN_FING
Feature description [info] UBP-type
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
75 sequences

BRAP_HUMAN  (Q7Z569), BRAP_MOUSE  (Q99MP8), EPT1_SCHPO  (O13747), 
ETP1_YEAST  (P38748), HDA6_CAEEL  (Q20296), HDAC6_HUMAN (Q9UBN7), 
HDAC6_MOUSE (Q9Z2V5), NOT_DROME   (Q9VVR1), SAD1_YEAST  (P43589), 
SIR2A_DICDI (Q54QE6), SNUT2_HUMAN (Q53GS9), SNUT2_MOUSE (Q3TIX9), 
SNUT2_PONAB (Q5R761), UB22A_XENLA (Q6GNI6), UB22B_XENLA (Q6DCJ1), 
UBP10_SCHPO (Q9USR2), UBP13_BOVIN (E1BMF7), UBP13_CHICK (E1BY77), 
UBP13_DANRE (F1QFS9), UBP13_HUMAN (Q92995), UBP13_MOUSE (Q5BKP2), 
UBP13_XENTR (F6V6I0), UBP14_ARATH (Q8L6Y1), UBP14_SCHPO (Q11119), 
UBP14_YEAST (P38237), UBP16_BOVIN (Q08DA3), UBP16_DANRE (A8HAL1), 
UBP16_HUMAN (Q9Y5T5), UBP16_MACFA (Q4R6X7), UBP16_MOUSE (Q99LG0), 
UBP16_RAT   (Q2KJ09), UBP16_XENLA (Q6PAW2), UBP16_XENTR (Q0VA64), 
UBP1_ARATH  (Q9FPT5), UBP20_BOVIN (A7Z056), UBP20_DANRE (A5PN09), 
UBP20_HUMAN (Q9Y2K6), UBP20_MOUSE (Q8C6M1), UBP20_PONAB (Q5R5Z6), 
UBP20_XENLA (B1WBD7), UBP20_XENTR (A0JM59), UBP22_ARATH (Q9LEW0), 
UBP22_BOVIN (P0C8Z3), UBP22_DANRE (A6H8I0), UBP22_HUMAN (Q9UPT9), 
UBP22_MOUSE (Q5DU02), UBP2_ARATH  (Q8W4N3), UBP33_BOVIN (A6QNM7), 
UBP33_DANRE (A5PMR2), UBP33_HUMAN (Q8TEY7), UBP33_MOUSE (Q8R5K2), 
UBP33_PONAB (Q5REG5), UBP33_XENTR (Q28CN3), UBP3_HUMAN  (Q9Y6I4), 
UBP3_MOUSE  (Q91W36), UBP44_AILME (D2HBJ8), UBP44_DANRE (Q7ZUM8), 
UBP44_HUMAN (Q9H0E7), UBP44_MOUSE (Q8C2S0), UBP44_XENTR (Q0V9G5), 
UBP45_HUMAN (Q70EL2), UBP45_MOUSE (Q8K387), UBP49_HUMAN (Q70CQ1), 
UBP49_MOUSE (Q6P9L4), UBP51_HUMAN (Q70EK9), UBP5_HUMAN  (P45974), 
UBP5_MOUSE  (P56399), UBP5_PONAB  (Q5R407), UBP7_SCHPO  (Q9P7S5), 
UBP8_SCHPO  (Q09738), UBP8_YEAST  (P50102), UBPA_DICDI  (P54201), 
UP44A_XENLA (Q6NTR6), UP44B_XENLA (Q5XGZ2), YQOE_CAEEL  (Q95QN6)
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PDB
[Detailed view]
16 PDB

2G43; 2G45; 2I50; 2L80; 2UZG; 3C5K; 3GV4; 3IHP; 3M99; 3MHH; 3MHS; 3PHD; 4FIP; 4FJC; 4FK5; 4MSX
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