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	Entry: PS50818

General information about the entry
Entry name	INTEIN_C_TER
Accession number	PS50818
Entry type	MATRIX
Date	MAY-2002 (CREATED); MAY-2002 (DATA UPDATE); MAR-2013 (INFO UPDATE).
PROSITE Documentation	PDOC00687
Name and characterization of the entry
Description	Intein C-terminal splicing motif profile.
Matrix / Profile	/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=22; /DISJOINT: DEFINITION=PROTECT; N1=3; N2=20; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.8533; R2=0.02263959; TEXT='NScore'; /CUT_OFF: LEVEL=0; SCORE=290; N_SCORE=7.4; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=249; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-8; D=-20; I=-20; B0=-60; B1=-60; E0=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105; A B C D E F G H I K L M N P Q R S T V W Y Z /I: B0=0; B1=0; BI=-105; BD=-105; /M: SY='Y'; M=-15,-11,-29, -9, -6, 3,-23, -5,-14, -1,-13,-10,-10, -2, -9, 0,-12, -8,-15, -5, 12, -9; /M: SY='V'; M= 1,-25,-13,-27,-26, -1,-24,-27, 20,-18, 7, 6,-24,-26,-25,-17, -8, 1, 34,-27, -9,-26; /M: SY='Y'; M=-19,-17,-28,-18,-17, 29,-28, 9, -2,-11, -1, -1,-16,-27,-11, -9,-18,-10, -9, 17, 55,-17; /M: SY='D'; M=-13, 27, -1, 33, 5,-29,-12, -6,-30, -8,-25,-23, 15,-17, -6,-12, 4, -3,-22,-41,-21, -1; /M: SY='L'; M= -6,-25,-20,-27,-22, 3,-30,-24, 23,-25, 26, 13,-24,-25,-21,-21,-18, -4, 20,-23, -3,-23; /M: SY='T'; M= -1, 1,-18, -1, 4,-16,-10,-10,-14, -7,-16,-13, 3,-12, -3, -9, 11, 12, -9,-28,-11, 0; /M: SY='V'; M= 3,-18, -3,-21,-22, -8,-21,-25, 10,-18, 1, 0,-17,-24,-22,-19, -4, 4, 23,-30,-13,-22; /I: I=-5; MD=-27; /M: SY='E'; M=-10, 0,-25, 7, 15,-17,-19, -7,-21, 2,-19,-15, -5, 11, 0, -6, -6, -9,-21,-21, -9, 6; D=-5; /I: I=-5; MD=-27; /M: SY='N'; M= -2, 10,-17, 7, 0,-18, 5, -1,-18, -2,-18,-12, 13,-11, -3, -3, 2, -3,-16,-22,-13, -2; D=-5; /I: I=-5; MI=-27; MD=-27; IM=-27; DM=-27; /M: SY='H'; M=-12, 0,-26, 1, 5,-22, -6, 42,-25, -8,-18, -6, 5,-16, 7, -4, -4,-13,-24,-27, 0, 4; D=-5; /I: I=-5; DM=-27; /M: SY='N'; M= -5, 14,-19, 2, -5,-10, -8, -2,-13, -4,-15,-11, 27,-20, -5, -2, 3, 0,-17,-30,-13, -5; /M: SY='F'; M=-16,-25,-24,-30,-25, 40,-25, -8, 5,-22, 9, 3,-20,-29,-25,-17,-20,-10, 0, 8, 37,-25; /I: I=-6; MD=-32; /M: SY='V'; M= -6,-27,-18,-30,-25, 7,-30,-20, 24,-24, 18, 12,-23,-26,-23,-20,-16, -4, 25,-21, -1,-25; D=-6; /I: I=-6; MI=-32; IM=-32; DM=-32; /M: SY='A'; M= 15,-14,-14,-20,-15, -7,-14,-20, 1,-15, -2, -3,-12,-17,-13,-17, 4, 8, 8,-23,-11,-14; /I: I=-5; MD=-25; /M: SY='N'; M= -1, 8,-22, 1, -3,-17, 1, -4,-18, -4,-20,-14, 15,-15, -5, -3, 1, -6,-17,-22,-12, -5; D=-5; /I: I=-5; MD=-25; /M: SY='G'; M= -5, -1,-21, -5, -7,-13, 14, -8,-19, -9,-17,-12, 6,-16, -7, -8, 2, -5,-17,-19,-11, -7; D=-5; /I: I=-5; MI=0; MD=-25; IM=0; DM=-25; /M: SY='I'; M= -6,-28,-15,-34,-27, 9,-30,-27, 27,-27, 16, 11,-22,-25,-24,-25,-17, -8, 22,-20, -1,-27; /M: SY='V'; M= -6,-28,-20,-31,-25, 8,-30,-24, 22,-23, 16, 11,-25,-23,-24,-21,-17, -5, 23,-15, 0,-25; /M: SY='V'; M= 5,-15, -9,-20,-18, -7,-21,-23, 7,-16, 1, -1,-14,-20,-18,-17, 3, 14, 18,-29,-11,-18; /M: SY='H'; M=-12, -3,-28, -3, -3,-20, -5, 62,-30, -7,-21, -5, 6,-19, 3, -2, -7,-17,-27,-26, 7, -3; /M: SY='N'; M=-10, 35,-21, 17, 3,-23, -3, 10,-20, 1,-29,-17, 52,-19, 8, 1, 9, -1,-30,-37,-19, 5; /M: SY='C'; M= -3,-11, 63,-18,-18,-18,-20,-23,-24,-21,-21,-18, -8,-27,-18,-21, 9, 8, -8,-44,-24,-18; /I: E0=0; E1=0; IE=-105; DE=-105;
Numerical results
UniProtKB/Swiss-Prot release number: 2013_05, total number of sequence entries in that release: 540052. Total number of hits in UniProtKB/Swiss-Prot: 106 hits in 94 different sequences Number of hits on proteins that are known to belong to the set under consideration: 106 hits in 94 different sequences Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences Number of false hits (on unrelated proteins): 0 hits in 0 different sequences Number of known missed hits: 8 Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0 Precision (true hits / (true hits + false positives)): 100.00 % Recall (true hits / (true hits + false negatives)): 92.98 %
Comments
MATRIX_TYPE: protein_domain Scaling database: UniProtKB/Swiss-Prot: reversed Matrix author: CJA_Sigrist Taxonomic range: Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses Maximum known number of repetitions of the pattern in a single protein: 3 VERSION: 1
Cross-references
UniProtKB/Swiss-Prot	True positive hits: DNAB_GUITH (O78411), DNAB_MYCBO (P59966), DNAB_MYCTU (P71715), DNAB_NOSS1 (Q8YZA1), DNAB_PORPU (P51333), DNAB_PORYE (Q1XDF3), DNAB_RHOMR (O30477), DNAB_SYNY3 (Q55418), DP2L_METHJ (Q2FSF9), DP2L_METMJ (A3CXE7), DP2L_PYRAB (Q9V2F4), DP2L_PYRHO (O57861), DP2L_PYRKO (Q5JET0), DPO3A_SYNY3 (P74750), DPOL_BPAPS (Q9T1Q3), DPOL_CEV01 (A7U6F1), DPOL_METJA (Q58295), DPOL_MIMIV (Q5UQR0), DPOL_PYRHO (O59610), DPOL_PYRKO (P77933), DPOL_PYRSD (Q51334), DPOL_THEAG (O33845), DPOL_THEFM (P74918), DPOL_THEG8 (Q9HH84), DPOL_THEHY (Q9HH05), DPOL_THELI (P30317), EF2_METKA (Q8TXJ4), GLMS_METJA (Q58815), GYRA_MYCFV (Q49166), GYRA_MYCGO (Q49467), GYRA_MYCKA (Q49608), GYRA_MYCLE (Q57532), GYRA_MYCMA (O33149), GYRA_MYCXE (P72065), GYRB_SYNY3 (P77966), HELS_METJA (Q58524), HELS_PYRKO (Q5JGV6), IF2P_METJA (Q57710), IF2P_PYRAB (Q9UZK7), IF2P_PYRFU (Q8U1R8), IF2P_PYRHO (O58822), IF2P_PYRKO (Q5JGR9), LONB_PYRAB (Q9UYC6), LONB_PYRHO (O58221), NRDEB_BACSU (O31875), NRDEB_BPSPB (O64173), PPSA_METJA (Q57962), RADA_PYRHO (O58001), RADA_PYRKO (Q5JET4), RECA_MYCBO (P0A5U5), RECA_MYCCI (Q9F417), RECA_MYCFA (Q9F416), RECA_MYCFV (Q9F415), RECA_MYCGS (Q9F414), RECA_MYCLE (P35901), RECA_MYCSH (Q9F410), RECA_MYCTH (Q9F407), RECA_MYCTU (P0A5U4), RFCS_HALWD (Q18E75), RFCS_METJA (Q58817), RFCS_METKA (Q8TZC4), RFCS_PYRAB (Q9V2G4), RFCS_PYRFU (Q8U4J3), RFCS_PYRHO (O57852), RFCS_PYRKO (Q5JHP2), RGYR_METJA (Q58907), RGYR_PYRHO (O58530), RGYR_PYRKO (Q6F598), RIR2_AQUAE (O67475), RPC2_DICDI (Q54IZ9), RPOA1_METJA (Q58445), RPOA2_METJA (Q58446), RTCB_METJA (Q58095), RTCB_METKA (Q8TUS2), RTCB_PYRAB (Q9V168), RTCB_PYRFU (Q8U0H4), RTCB_PYRHO (O59245), TF2B_METJA (Q58192), TOP1_PYRFU (O73954), VATA_PYRAB (Q9UXU7), VATA_PYRFU (Q8U4A6), VATA_PYRHO (O57728), VATA_THEAC (Q9P997), VATA_THEVO (Q97CQ0), VATA_YEAST (P17255), VATB_METKA (Q8TUT0), Y043_METJA (Q60348), Y1054_METJA (Q58454), Y1461_MYCTU (P67125), Y1496_MYCBO (P67126), Y450_MYCPN (Q50362), Y593_MYCLE (Q49689), Y781_METJA (Q58191), Y832_METJA (Q58242) False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile): CLPP_CHLMO (P42379), DNAB_MYCIT (Q9F5P4), DNAB_MYCLE (P46394), DP2L_HALMA (Q5UZ40), DP2L_HALSA (Q9HMX8), DP2L_HALWD (Q18ER3), RIR1_IIV6 (O55716), VATA_CANTR (P38078) Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
PDB [Detailed view]	1AM2; 1MI8; 2CW7; 2CW8; 2IN0; 2IN9; 2L8L; 2LQM; 4E2T; 4E2U;

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