To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Entry: PS50868

General information about the entry

Entry name [info] POST_SET
Accession [info] PS50868
Entry type [info] MATRIX
Date [info] 01-NOV-2002 CREATED; 10-MAY-2017 DATA UPDATE; 25-OCT-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC50280
Associated ProRule [info] PRU00155

Name and characterization of the entry

Description [info] Post-SET domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=17;
/DISJOINT: DEFINITION=PROTECT; N1=2; N2=16;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1220000; R2=0.0163836; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=161.0268402; R2=0.1543624; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=359; H_SCORE=216; N_SCORE=8.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=268; H_SCORE=202; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-11; D=-20; I=-20; B0=-60; B1=-60; E0=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B0=0; B1=0; BI=-105; BD=-105;
/M: SY='E'; M= -7,  0,-25, -2,  6,-24,-16, -8,-17,  5,-17,-10,  1,-13,  2, -4, -2, -6,-11,-30,-18,  4;
/M: SY='K'; M= -4, -5,-26, -7,  5,-25,-14, -8,-25, 14,-20,-12, -5,-10,  6,  9, -3,-10,-19,-27,-16,  4;
/M: SY='M'; M=-10,-18,-20,-20, -9, -9,-28,-13, -2, -3,  0,  2,-16,-18,  0, -8,-11, -9, -1,-22, -7, -6;
/M: SY='P'; M= -9, -5,-26,  0,  1,-27,-19,-14,-22, -2,-22,-15, -8, 15, -2,-10, -4, -4,-16,-32,-22, -1;
/M: SY='C'; M=-40,-40,110,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40;
/M: SY='Y'; M=-13,-16,-19,-19, -9, -3,-25,  6,-13, -6, -7, -5, -8,-23, -2, -4, -9,-12,-14,-14,  9, -8;
/M: SY='C'; M=-40,-40,110,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40;
/M: SY='G'; M= -2, -7,-30, -8,-10,-30, 47,-17,-38,-10,-37,-27,  3,-19,-15,-15,  0,-18,-29,-22,-28,-14;
/M: SY='A'; M= 18, -9,-10, -9, -1,-19, -5,-13,-16, -4,-15,-11, -6,-11, -3, -7, 18,  6,-10,-28,-18, -2;
/M: SY='P'; M=  1,-10,-21, -7,  2,-26,-17,-15,-16,  0,-18,-12,-10,  4, -3, -8,  0, -1, -8,-32,-21,  0;
/M: SY='N'; M= -7,  5,-18, -4, -1,-22, -8, -2,-23,  2,-22,-14, 17,-18, -1, -1,  4, -4,-20,-30,-16, -1;
/M: SY='C'; M=-40,-40,110,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40,-40;
/M: SY='R'; M= -7,-11,-24,-18, -3,-25,-20, -7,-20, 12,-14, -5, -3,-18,  5, 27, -4, -4,-19,-28,-18, -2;
/M: SY='G'; M= -3, -6,-29,-10,-11,-29, 31,-10,-35, -2,-33,-23,  3,-18,-10, -6,  0,-16,-27,-24,-24,-11;
/M: SY='Y'; M=-12,-23,-19,-25,-16,  8,-24, -9, -9,-10, -8, -4,-18,-26,-12,-11,-11, -7, -9,  3, 11,-16;
/M: SY='L'; M= -7,-34,-11,-34,-26, -1,-35,-27, 18,-17, 27, 18,-27,-27,-18,-19,-16, -9, 11,-21,-10,-25;
/M: SY='G'; M= -9, -6,-27,-10,-12,-16, 12, -9,-26,-12,-25,-18,  5,-16,-11,-12, -2,-13,-23,-21,-13,-12;
/I:         E0=0; E1=0; IE=-105; DE=-105;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_10 which contains 556'006 sequence entries.


Total number of hits 123 in 123 different sequences
Number of true positive hits 123 in 123 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 9
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 93.18 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] window20_shuffled
Author [info] N_Hulo
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] Post-SET
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
123 sequences

ASH1L_HUMAN (Q9NR48    ), ASH1L_MOUSE (Q99MY8    ), ASH1_DROME  (Q9VW15    ), 
ASHH1_ARATH (Q84WW6    ), ASHH2_ARATH (Q2LAE1    ), ASHH3_ARATH (Q945S8    ), 
ASHH4_ARATH (Q9M1X9    ), ASHR3_ARATH (Q949T8    ), ATX1_ARATH  (Q9C5X4    ), 
ATX2_ARATH  (P0CB22    ), ATX3_ARATH  (Q9M364    ), ATX4_ARATH  (Q9SUE7    ), 
ATX5_ARATH  (Q8GZ42    ), C1716_DROME (Q9VYD1    ), CLR4_SCHPO  (O60016    ), 
DIM5_NEUCR  (Q8X225    ), KMT2A_HUMAN (Q03164    ), KMT2A_MOUSE (P55200    ), 
KMT2B_HUMAN (Q9UMN6    ), KMT2B_MOUSE (O08550    ), KMT2C_HUMAN (Q8NEZ4    ), 
KMT2C_MOUSE (Q8BRH4    ), KMT2D_HUMAN (O14686    ), KMT2D_MOUSE (Q6PDK2    ), 
MES4_CAEEL  (Q9NH52    ), MES4_DROME  (Q8MT36    ), MET2_CAEEL  (P34544    ), 
NSD1_HUMAN  (Q96L73    ), NSD1_MOUSE  (O88491    ), NSD2_HUMAN  (O96028    ), 
NSD2_MOUSE  (Q8BVE8    ), NSD3_HUMAN  (Q9BZ95    ), NSD3_MOUSE  (Q6P2L6    ), 
SE1BA_DANRE (Q1LY77    ), SET1A_HUMAN (O15047    ), SET1B_CHICK (Q5F3P8    ), 
SET1B_HUMAN (Q9UPS6    ), SET1B_MOUSE (Q8CFT2    ), SET1B_XENLA (Q66J90    ), 
SET1B_XENTR (Q08D57    ), SET1_ASHGO  (Q75D88    ), SET1_ASPFU  (Q4WNH8    ), 
SET1_ASPOR  (Q2UMH3    ), SET1_CANAL  (Q5ABG1    ), SET1_CANGA  (Q6FKB1    ), 
SET1_CHAGB  (Q2GWF3    ), SET1_COCIM  (Q1DR06    ), SET1_CRYNB  (P0CO27    ), 
SET1_CRYNJ  (P0CO26    ), SET1_DEBHA  (Q6BKL7    ), SET1_DICDI  (Q54HS3    ), 
SET1_DROME  (Q5LJZ2    ), SET1_EMENI  (Q5B0Y5    ), SET1_GIBZE  (Q4I5R3    ), 
SET1_KLULA  (Q6CIT4    ), SET1_NEUCR  (Q8X0S9    ), SET1_PLAF7  (C6KTD2    ), 
SET1_SCHPO  (Q9Y7R4    ), SET1_USTMA  (Q4PB36    ), SET1_YARLI  (Q6CEK8    ), 
SET1_YEAST  (P38827    ), SET23_CAEBR (A8XI75    ), SET23_CAEEL (Q95Y12    ), 
SET2_ASHGO  (Q757Y8    ), SET2_ASPFU  (Q4WTT2    ), SET2_ASPOR  (Q2UTN6    ), 
SET2_CAEEL  (Q18221    ), SET2_CANAL  (Q59XV0    ), SET2_CANGA  (Q6FX50    ), 
SET2_CHAGB  (Q2H988    ), SET2_COCIM  (Q1DU03    ), SET2_CRYNB  (P0CO29    ), 
SET2_CRYNJ  (P0CO28    ), SET2_DEBHA  (Q6BM04    ), SET2_EMENI  (Q5ASA5    ), 
SET2_GIBZE  (Q4IB50    ), SET2_KLULA  (Q6CXP5    ), SET2_NEUCR  (Q7RZU4    ), 
SET2_SCHPO  (O14026    ), SET2_USTMA  (Q4PBL3    ), SET2_YARLI  (Q6C5G5    ), 
SET2_YEAST  (P46995    ), SETB1_DROME (Q32KD2    ), SETB1_DROPS (Q28Z18    ), 
SETB1_HUMAN (Q15047    ), SETB1_MOUSE (O88974    ), SETB1_XENLA (Q6INA9    ), 
SETB2_XENLA (Q6YI93    ), SETD2_HUMAN (Q9BYW2    ), SETD2_MOUSE (E9Q5F9    ), 
SETMR_BOVIN (Q0VD24    ), SETMR_HUMAN (Q53H47    ), SETMR_MOUSE (Q80UJ9    ), 
SETMR_RAT   (Q5I0M0    ), STB1B_DANRE (Q08BR4    ), SUV39_DROME (P45975    ), 
SUV39_DROPS (Q294B9    ), SUV91_BOVIN (Q2NL30    ), SUV91_HUMAN (O43463    ), 
SUV91_MOUSE (O54864    ), SUV91_PONAB (Q5RB81    ), SUV91_XENLA (Q6NRE8    ), 
SUV92_BOVIN (Q32PH7    ), SUV92_CHICK (Q5F3W5    ), SUV92_HUMAN (Q9H5I1    ), 
SUV92_MACFA (Q4R3E0    ), SUV92_MOUSE (Q9EQQ0    ), SUV92_XENTR (Q28CQ7    ), 
SUVH1_ARATH (Q9FF80    ), SUVH1_TOBAC (Q93YF5    ), SUVH3_ARATH (Q9C5P4    ), 
SUVH4_ARATH (Q8GZB6    ), SUVH5_ARATH (O82175    ), SUVH6_ARATH (Q8VZ17    ), 
SUVH7_ARATH (Q9C5P1    ), SUVH8_ARATH (Q9C5P0    ), SUVR3_ARATH (Q9SRV2    ), 
SUVR5_ARATH (O64827    ), SV91A_DANRE (Q6DGD3    ), TRR_DROME   (Q8IRW8    ), 
TRX1_ORYSJ  (Q6K431    ), TRX_DROME   (P20659    ), TRX_DROVI   (Q24742    )
» more

UniProtKB/Swiss-Prot
False negative sequences
9 sequences

EHMT2_HUMAN (Q96KQ7    ), EHMT2_MOUSE (Q9Z148    ), SET25_CAEEL (G5EEU2    ), 
STB1A_DANRE (Q1L8U8    ), SUVH3_CHLRE (Q5QD03    ), SUVHA_ARATH (Q3EC60    ), 
SUVR1_ARATH (Q946J2    ), SUVR2_ARATH (Q9FNC7    ), SUVR4_ARATH (Q8W595    )
» more

PDB
[Detailed view]
30 PDB

1PEG; 2R3A; 2W5Y; 2W5Z; 3BO5; 3OOI; 3OPE; 4FMU; 4H12; 4QEN; 4QEO; 4QEP; 4YNM; 4YNP; 4YPA; 4YPE; 4YPU; 4Z4P; 5F59; 5F5E; 5F6K; 5F6L; 5LSS; 5LSU; 5LSX; 5LSY; 5LSZ; 5LT6; 5LT7; 5LT8
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission