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Entry: PS50900

General information about the entry

Entry name [info] PLAC
Accession [info] PS50900
Entry type [info] MATRIX
Date [info] 01-OCT-2003 CREATED; 10-MAY-2017 DATA UPDATE; 20-DEC-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC50900
Associated ProRule [info] PRU00233

Name and characterization of the entry

Description [info] PLAC domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=40;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=36;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1332045; R2=0.0106719; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=913.1008301; R2=4.1092439; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=597; H_SCORE=3366; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=410; H_SCORE=2598; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: B0=-50; E0=-50; M0=-9; D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B0=0; B1=0; BI=-105; BD=-105;
/M: SY='P'; M= -3,-11,-24,-12, -2,-18,-20,-14, -8, -1,-11, -4,-11,  6, -2, -4, -3,  1, -7,-26,-14, -3;
/M: SY='D'; M= -5,  7,-27, 10, -2,-24,  1,-12,-27, -5,-26,-20,  4, -4, -7,-11,  2, -2,-22,-16,-16, -4;
/M:         M= -2, -1,-26,  0, -3,-19, -9,  0,-17, -7,-13, -6, -3, -1, -2, -9, -5, -9,-17,-23, -8, -4;
/M: SY='S'; M= -8, -1,-22,  0,  0,-14,-18, -3,-14, -2,-11, -8, -1,-15, -1, -2,  1,  0, -9,-28, -8, -1;
/M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30;
/M: SY='K'; M= -3, -4,-21, -7,  3,-21,-19,-10,-14, 10,-15, -4, -4,-12,  8,  6,  3,  7, -8,-25,-11,  5;
/M: SY='D'; M=-17, 34,-29, 47, 13,-35, -6, -1,-37,  6,-29,-25, 17,-13,  1,  3, -1,-10,-28,-35,-19,  6;
/M: SY='D'; M= -3,  8,-23, 10,  2,-23,-14, -6,-15, -1,-18,-11,  4,-14,  4, -3,  3, -4,-12,-27,-10,  2;
/I:         I=-4; MD=-21;
/M: SY='P'; M= -7,  2,-21,  3,  2,-20, -7, -5,-18,  5,-19,-11,  3,  9,  3,  3, -2, -4,-18,-19,-13,  1; D=-4;
/I:         I=-4; MD=-21;
/M: SY='W'; M= -5, -5,-13, -6, -1,  1, -9, -5, -5, -7, -1, -4, -4,-10, -4, -6, -4, -3, -7,  2,  2, -2; D=-4;
/I:         I=-4; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='F'; M=  0,-14, -5,-18,-12,  6, -9,-17,-13,-18, -6, -9, -9,-20,-17,-17,  2,  1, -7,-21, -7,-13;
/M: SY='S'; M=  5, -9,-19,-12,-10,-18,  1,-11,-14,-10,-17,-11, -3,-10, -9, -8,  9,  4, -7,-28,-16,-11;
/M: SY='F'; M=-15, -8,-24,-17,-16, 23,-21, -2, -7,-11, -7, -6,  1,-24,-16, -9,-11, -6,-11,  0, 17,-15;
/M: SY='C'; M=-11,-20,107,-29,-29,-16,-30,-26,-27,-28,-18,-18,-20,-39,-28,-28,-11,-10,-10,-43,-20,-29;
/M: SY='E'; M= -9,  1,-28,  5, 10,-25,-16, -3,-23,  6,-21,-11, -2,  3,  9,  9, -2, -7,-21,-25,-12,  7;
/M: SY='L'; M= -8,-19,-19,-24,-18,  1,-24,-16, 12,-19, 20, 17,-17,-23,-14,-15,-14,  3,  8,-16, -3,-16;
/M: SY='I'; M=  3,-22,-19,-25,-16, -5,-25,-23, 20,-20, 12,  7,-18,-20,-16,-21, -9, -4, 19,-25, -8,-18;
/M: SY='K'; M= -8,-13,-24,-13, -6,-17,-23,-15, -7, 15,-12, -3,-11,-13, -5, 15, -9, -6,  2,-24,-10, -7;
/M: SY='Q'; M= -1, -8,-23, -9,  4,-19,-18, -9,-12,  4, -4, -2, -7,-15,  9,  2, -4, -5,-11,-23,-11,  6;
/M: SY='N'; M=  3, -1,-20, -8, -6,-14, -8, -3,-14,  1,-13, -3,  5,-16, -3,  0,  0, -4,-12,-25,-11, -5;
/M: SY='R'; M=-11,  3,-28,  0,  2,-25,  3,  9,-30,  9,-25,-13, 12,-17,  5, 16, -3,-12,-26,-25,-13,  1;
/M: SY='L'; M=-12,-23,-23,-24,-17, 10,-26, -8,  8,-15, 23, 15,-21,-26,-12, -8,-21, -9,  1,-10, 15,-16;
/M: SY='C'; M=-10,-21,111,-30,-29,-18,-30,-29,-27,-30,-16,-17,-21,-39,-29,-29,-11,-10, -9,-48,-28,-29;
/M: SY='Q'; M= -4,  2,-23,  2,  6,-27,  0, -5,-23,  2,-25,-13,  6,-13, 12,  2,  9, -2,-19,-29,-17,  8;
/M: SY='H'; M=-11, -4,-15, -6, -8,-11,-20,  7,-11, -6, -9, -5,  0,-21, -5, -1, -5, -6, -9,-25,  0, -9;
/M: SY='K'; M=-12, -8,-33, -4,  4,-24,-20, -7,-21, 15,-22, -8, -9, 15,  1,  4,-12,-12,-21,-16,-12,  1;
/M: SY='Y'; M=-13,-10,-24,-10,-10,  1,-18, -4, -9, -5, -5, -5,-10,-22, -9,  2, -9, -2, -6, -9, 15,-12;
/M: SY='Y'; M=-16,-25,-27,-28,-24, 29,-29, -1,  7,-17,  6,  6,-23,-29,-18,-15,-21,-10,  1, 21, 46,-22;
/M: SY='R'; M= -5, -5,-23, -9, -6,-17, -7, -6,-18,  4,-18,-10,  2,-17,  1, 14,  2,  0,-14,-21, -8, -4;
/M: SY='Q'; M= -4,  1,-23,  0, 10,-25,-18, -7,-19,  9,-16, -8, -1,-10, 16,  4,  3,  6,-16,-25,-12, 13;
/M: SY='F'; M=-10,-14,-23,-20, -9, 13,-24,-13, -4, -8,  1, -1, -9,-20, -8, -4,-11, -6, -6,-13,  3, -8;
/M: SY='C'; M= -9,-19,111,-28,-28,-20,-28,-29,-29,-29,-21,-20,-18,-38,-28,-29, -7, -8,-10,-49,-29,-28;
/M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30;
/M: SY='R'; M=-10, -8,-26, -9, -1,-14,-13, -1,-25, 16,-20, -9, -1,-17,  5, 27, -4, -8,-18,-20, -7,  0;
/M: SY='T'; M=  6,  0,-10, -4, -4,-16, -8,-14,-16,-10,-22,-16,  6,-10, -4,-10, 32, 33, -6,-36,-16, -4;
/M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30;
/M: SY='T'; M=  4, -4,-17, -8, -3,-16,-13,-12,-14, -5,-12,-11,  1, -8, -4, -2, 11, 13, -9,-29,-15, -4;
/M: SY='R'; M= -9, -8,-27, -7,  0,-13,-17, -5,-16,  0, -8, -6, -8, -6,  1,  2,-10,-10,-16,-21, -8, -1;
/M: SY='A'; M=  1,-15,-23,-16, -9, -7,-15,-14, -9, -7,-12, -7,-12,  0, -7,-11, -3, -3, -6,-18, -6, -9;
/M: SY='H'; M= -8, -3,-26, -6, -7,-18,  7,  9,-21,-12,-18,-10,  4,-13, -4,-11, -1, -8,-21,-23, -7, -7;
/I:         E0=0; E1=0; IE=-105; DE=-105;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_12 which contains 556'388 sequence entries.


Total number of hits 39 in 39 different sequences
Number of true positive hits 39 in 39 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.50 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] PLAC
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
39 sequences

ATL1_HUMAN  (Q8N6G6    ), ATL1_MOUSE  (Q8BLI0    ), ATL2_HUMAN  (Q86TH1    ), 
ATL2_MOUSE  (Q7TSK7    ), ATL3_HUMAN  (P82987    ), ATL4_HUMAN  (Q6UY14    ), 
ATL4_MOUSE  (Q80T21    ), ATL4_RAT    (Q4FZU4    ), ATS10_HUMAN (Q9H324    ), 
ATS10_MOUSE (P58459    ), ATS12_HUMAN (P58397    ), ATS12_MOUSE (Q811B3    ), 
ATS14_HUMAN (Q8WXS8    ), ATS16_HUMAN (Q8TE57    ), ATS16_MOUSE (Q69Z28    ), 
ATS17_HUMAN (Q8TE56    ), ATS18_HUMAN (Q8TE60    ), ATS18_MOUSE (Q4VC17    ), 
ATS19_HUMAN (Q8TE59    ), ATS19_MOUSE (P59509    ), ATS2_BOVIN  (P79331    ), 
ATS2_HUMAN  (O95450    ), ATS2_MOUSE  (Q8C9W3    ), ATS3_HUMAN  (O15072    ), 
ATS6_HUMAN  (Q9UKP5    ), ATS7_HUMAN  (Q9UKP4    ), ATS7_MOUSE  (Q68SA9    ), 
ATS7_RAT    (Q1EHB3    ), MADD4_CAEEL (P90884    ), MIG17_CAEEL (Q20930    ), 
NAS5_CAEEL  (P91828    ), PCSK6_HUMAN (P29122    ), PCSK6_RAT   (Q63415    ), 
PPN1_CAEEL  (O76840    ), PPN_DROME   (Q868Z9    ), PPN_HUMAN   (O95428    ), 
PPN_MOUSE   (Q9EPX2    ), THSD4_HUMAN (Q6ZMP0    ), THSD4_MOUSE (Q3UTY6    )
» more

UniProtKB/Swiss-Prot
False negative sequences
1 sequence

PCSK5_HUMAN (Q92824    )

		

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