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Entry: PS50998

General information about the entry

Entry name [info] GLA_2
Accession [info] PS50998
Entry type [info] MATRIX
Date [info] 01-JUN-2004 CREATED; 10-MAY-2017 DATA UPDATE; 27-SEP-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC00011
Associated ProRule [info] PRU00463

Name and characterization of the entry

Description [info] Gla domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=47;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=43;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.0481772; R2=0.0159966; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2447.1208496; R2=2.4093959; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=404; H_SCORE=3421; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=279; H_SCORE=3119; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='A'; M= 31, -5,-10,-11, -5,-20,  0,-15,-15,-10,-19,-15, -1,-10, -5,-15, 24,  9, -5,-29,-20, -5;
/M: SY='N'; M=-10, 40,-20, 20,  0,-20,  0, 10,-20,  0,-30,-20, 60,-20,  0,  0, 10,  0,-30,-40,-20,  0;
/M: SY='S'; M= 10,  0,-10,  0,  0,-20,  0,-10,-20,-10,-30,-20, 10,-10,  0,-10, 40, 20,-10,-40,-20,  0;
/M: SY='F'; M=-15,-30,-20,-35,-25, 47,-30,-20,  9,-30, 29,  9,-25,-30,-31,-20,-25,-10,  5, -4, 16,-25;
/M: SY='F'; M=-12, -9,-24,-13,-11, 10,-18, -4,-10,-11, -5, -3, -5,-22, -9, -8,-11, -8,-10, -6,  6, -9;
/M: SY='L'; M=-11,-20,-21,-22,-12, 13,-22,-16,  0,-17, 14,  3,-17,-23,-16, -9,-14, -5, -1,-12,  1,-13;
/M: SY='E'; M= -2,  5,-26,  8, 27,-27, -4, -5,-28,  4,-21,-18,  3, -8,  8,  3,  3, -8,-24,-28,-20, 17;
/M: SY='E'; M=  0, -5,-25, -3, 20,-17,-19,-11,-11, -5, -8, -9, -8, -4,  3,-10, -2, -6,-12,-26,-15, 11;
/M: SY='M'; M= -5,-19,-23,-22,-15, -3,-13,-14,  0,-10,  5,  7,-14,-19,-11, -2,-12, -8, -1,-18, -5,-14;
/M: SY='R'; M= -8, -1,-27,  1,  9,-22,-14, -8,-22, 12,-17,-11, -2,-13,  6, 13, -5, -7,-16,-22,-12,  7;
/M: SY='P'; M= -3,-13,-28,-12, -1,-21,-19,-12,-14,  2,-10, -7,-12, 13,  2,  2, -8, -6,-16,-23,-15, -1;
/M: SY='G'; M=  0, -6,-23,-10,-15,-17, 24,-16,-21,-16,-20,-14,  2,-15,-15,-16,  4, -3,-14,-24,-18,-16;
/M: SY='N'; M= -8,  7,-25,  4,  0,-22,-10, -4,-19,  4,-23,-14, 14,  3, -3, -2,  1, -3,-20,-32,-17, -2;
/M: SY='L'; M= -1,-12,-19,-12,-10, -7,-19,-15,  3,-18, 12,  2,-12,-17,-11,-16, -6, -2,  1,-27,-10,-11;
/M: SY='E'; M=-10, -2,-34,  6, 32,-31,-20, -6,-25,  4,-24,-17, -7, 30, 15, -5, -4,-10,-30,-28,-22, 21;
/M: SY='R'; M=-13,-15,-26,-16, -6,-10,-22, -7,-12,  8,  2,  0,-10,-22,  1, 31,-14, -7,-10,-19, -4, -6;
/M: SY='E'; M=-10, 10,-30, 20, 60,-30,-20,  0,-30, 10,-20,-20,  0,  0, 20,  0,  0,-10,-30,-30,-20, 40;
/M: SY='C'; M= -4,-15, 50,-20,-17,-18,-21,-21,-23,-16,-17,-15,-12,-22,-16,-11, -2, -4,-11,-39,-23,-18;
/M: SY='M'; M=-10,-11,-23,-16, -9, -9,-24, -4,  2, -7,  4,  7, -7,-21,  1, -2,-11, -4, -2,-21, -1, -6;
/M: SY='E'; M= -9,  0,-28,  5, 30,-25,-18, -2,-28, 17,-20,-15, -1, -9, 13, 26, -3, -9,-23,-25,-16, 20;
/M: SY='E'; M=-10, 10,-30, 20, 60,-30,-20,  0,-30, 10,-20,-20,  0,  0, 20,  0,  0,-10,-30,-30,-20, 40;
/M: SY='V'; M= -3,-19,-19,-23,-17, -5,-26,-21, 12,-10,  6,  5,-17,-21,-15,-10, -9,  1, 16,-23, -6,-17;
/M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30;
/M: SY='E'; M= -5, 13,-23, 17, 29,-26,-12, -3,-24,  1,-23,-19,  9, -7,  8, -5, 11,  1,-21,-34,-19, 18;
/M: SY='Y'; M=-13, -9,-25, -7, -9, 10,-24, -5, -5,-13,  6, -1,-13,-23,-12,-11,-16, -8, -8, -7, 17,-11;
/M: SY='E'; M=-12, 12,-27, 12, 27,-14,-17,  5,-22,  2,-19,-16, 10,-11,  7, -3, -1, -7,-25,-21, -1, 16;
/M: SY='E'; M=-10, -2,-29,  4, 26,-20,-21, -4,-19,  1,-14,-11, -6,  6,  6, -4, -5, -9,-20,-27,-15, 15;
/M: SY='A'; M= 27, -6,-17, -9, -6,-21, -7,-18,-12,-11,-11,-11, -9,  2,-10,-19,  4, -3, -5,-24,-20, -9;
/M: SY='C'; M=-14,-15, 45,-21,-16,-16,-25,-15,-28, -3,-19,-14,-11,-30,-12, 11,-10,-10,-14,-34,-18,-16;
/M: SY='E'; M=-13, 18,-30, 29, 46,-32,-18,  0,-32,  9,-22,-22,  5, -4, 15,  3, -1,-10,-29,-32,-19, 30;
/M: SY='V'; M= -5,-14,-23,-15, -1, -9,-25, -9,  4, -9, -1,  0,-13,-17, -5, -7, -9, -8,  5,-23, -6, -5;
/M: SY='F'; M=-16,-27,-22,-32,-24, 42,-29,-10,  8,-23, 19, 13,-22,-29,-24,-17,-22,-10,  2,  2, 28,-23;
/M: SY='A'; M= 16, -3,-20, -4, 16,-23,-10, -9,-16, -1,-13, -9, -6, -8,  5, -7,  4, -5,-12,-24,-18, 11;
/M: SY='D'; M=-14, 23,-24, 27,  4,-19,-12,  2,-23, -4,-18,-15, 17,-16, -3, -5,  1, -3,-20,-31,-10,  0;
/M: SY='B'; M= -8,  6,-23,  6,  2,-22,-16,  1,-18,  1,-18,-11,  5,-11,  3,  3,  2,  2,-13,-30,-12,  2;
/M: SY='E'; M= -7, -3,-26,  0, 11,-17,-21,  5,-10, -4,-12, -7, -5,-10,  3, -8, -4, -7,-11,-22, -2,  5;
/I:         I=-6; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='G'; M= -3, -3,-28, -2, -6,-28, 26,-13,-31, -2,-25,-15,  2,-16, -6, -3, -2,-12,-23,-23,-21, -7;
/M: SY='T'; M= -8,-15,-17,-23,-19, 16,-27,-19,  4,-19,  5,  0,-12,-19,-19,-16, -2, 18,  5,-15,  7,-19;
/M: SY='Q'; M=-10,  0,-26,  0,  3,-21,-20, -7,-10,  4,-11, -3, -1,-12,  6,  2, -6, -5,-10,-26,-11,  4;
/M: SY='E'; M= 10, -1,-22, -2, 19,-24,-14, -7,-19,  3,-15,-12, -4, -8, 11, -3,  3, -4,-16,-23,-14, 15;
/M: SY='F'; M= 15,-20,-15,-30,-20, 30,-15,-19, -5,-20,  0, -5,-15,-20,-25,-20, -5, -5,  0, -5,  6,-20;
/M: SY='W'; M=-20,-29,-39,-29,-25, 21,-25, -4, -9,-15, -9, -9,-29,-30,-15,-15,-29,-19,-19, 87, 56,-20;
/M: SY='R'; M= -4, -5,-24, -8, -1,-21,-14, -5,-17,  8,-17, -8,  1,-12,  6, 15,  0, -2,-13,-24,-11,  1;
/M: SY='R'; M= -2, -8,-24,-10, -2,-20,-15, -7,-19, 15,-17, -8, -3,-15,  2, 22, -3, -3,-11,-22,-11, -2;
/M: SY='Y'; M=-20,-22,-29,-24,-22, 36,-30, 12,  2,-14,  2,  1,-20,-30,-15,-12,-20,-10, -7, 25, 70,-22;
/M: SY='Y'; M=-12,-15,-23,-19,-16, 20,-23, -4, -3,-12, -2, -3,-11,-22,-14,-11, -9, -3, -4, -3, 25,-16;
/M: SY='G'; M= -4,  6,-28, 10, -7,-29, 31,-12,-33,-10,-26,-19,  5,-17,-11,-10, -1,-14,-25,-25,-23, -9;
/I:         E1=0; IE=-105; DE=-105;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_09 which contains 555'594 sequence entries.


Total number of hits 122 in 122 different sequences
Number of true positive hits 122 in 122 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] Gla
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
122 sequences

FA101_PSETE (Q1L659    ), FA102_PSETE (Q1L658    ), FA10_BOVIN  (P00743    ), 
FA10_CHICK  (P25155    ), FA10_HUMAN  (P00742    ), FA10_MOUSE  (O88947    ), 
FA10_RABIT  (O19045    ), FA10_RAT    (Q63207    ), FA10_TROCA  (Q4QXT9    ), 
FA7_BOVIN   (P22457    ), FA7_HUMAN   (P08709    ), FA7_MOUSE   (P70375    ), 
FA7_PANPA   (Q2F9P4    ), FA7_PANTR   (Q2F9P2    ), FA7_RABIT   (P98139    ), 
FA7_RAT     (Q8K3U6    ), FA9_BOVIN   (P00741    ), FA9_CANLF   (P19540    ), 
FA9_CHICK   (Q804X6    ), FA9_FELCA   (Q6SA95    ), FA9_HUMAN   (P00740    ), 
FA9_MOUSE   (P16294    ), FA9_PANTR   (Q95ND7    ), FA9_PIG     (P16293    ), 
FA9_RAT     (P16296    ), FAXC_OXYMI  (Q58L95    ), FAXC_OXYSU  (Q58L96    ), 
FAXC_PSETE  (Q56VR3    ), FAXD1_DEMVE (A6MFK7    ), FAXD1_NOTSC (P82807    ), 
FAXD2_DEMVE (A6MFK8    ), FAXD2_NOTSC (Q58L94    ), FAXD_CRYNI  (B5G6G5    ), 
FAXD_HOPST  (P83370    ), FAXD_PSEPO  (Q58L93    ), FAXD_TROCA  (P81428    ), 
GAS6_HUMAN  (Q14393    ), GAS6_MOUSE  (Q61592    ), GAS6_RAT    (Q63772    ), 
MGP_ARGRE   (Q800Y2    ), MGP_BOVIN   (P07507    ), MGP_CHICK   (O42413    ), 
MGP_CHILA   (Q6QN06    ), MGP_GALGA   (P56620    ), MGP_HUMAN   (P08493    ), 
MGP_MOUSE   (P19788    ), MGP_PIG     (Q8MJ39    ), MGP_PONAB   (Q5RDP6    ), 
MGP_RABIT   (P47841    ), MGP_RAT     (P08494    ), OST2A_ONCMY (A0A024QYT3), 
OST2B_ONCMY (K9J977    ), OSTC1_DIPSG (P86867    ), OSTC1_SOLSE (Q1EG28    ), 
OSTC2_DIPSG (K7NTD0    ), OSTC2_MOUSE (P86547    ), OSTC2_SOLSE (P86863    ), 
OSTCN_ARGRE (Q800Y1    ), OSTCN_ATEGE (A2D4U1    ), OSTCN_BISPR (P83489    ), 
OSTCN_BOVIN (P02820    ), OSTCN_CAMBA (P86314    ), OSTCN_CAMDR (P86313    ), 
OSTCN_CANLF (P81455    ), OSTCN_CAPHI (P0C225    ), OSTCN_CHICK (P02822    ), 
OSTCN_CYPCA (Q7LZI4    ), OSTCN_DANRE (P83238    ), OSTCN_DRONO (P15504    ), 
OSTCN_FELCA (P02821    ), OSTCN_GORGO (P84349    ), OSTCN_HOMNE (P84351    ), 
OSTCN_HORSE (P83005    ), OSTCN_HUMAN (P02818    ), OSTCN_LAMGU (P86315    ), 
OSTCN_LEPMA (P28317    ), OSTCN_MACEU (P0C226    ), OSTCN_MACFA (P02819    ), 
OSTCN_MACMU (A2D670    ), OSTCN_MACNE (A2T6K4    ), OSTCN_MOUSE (P86546    ), 
OSTCN_PANTR (P84348    ), OSTCN_PIG   (Q8HYY9    ), OSTCN_PONPY (P84350    ), 
OSTCN_RABIT (P39056    ), OSTCN_RAT   (P04640    ), OSTCN_SPAAU (P40148    ), 
OSTCN_XENLA (P40147    ), OSTCN_XENTR (Q6DJ00    ), OSTCN_XIPGL (P02823    ), 
OSTR_MOUSE  (P54615    ), PROC_BOVIN  (P00745    ), PROC_CANLF  (Q28278    ), 
PROC_HUMAN  (P04070    ), PROC_MOUSE  (P33587    ), PROC_PIG    (Q9GLP2    ), 
PROC_RABIT  (Q28661    ), PROC_RAT    (P31394    ), PROS_BOVIN  (P07224    ), 
PROS_HUMAN  (P07225    ), PROS_MACMU  (Q28520    ), PROS_MOUSE  (Q08761    ), 
PROS_RABIT  (P98118    ), PROS_RAT    (P53813    ), PROZ_BOVIN  (P00744    ), 
PROZ_HUMAN  (P22891    ), PROZ_MOUSE  (Q9CQW3    ), THRB_BOVIN  (P00735    ), 
THRB_HUMAN  (P00734    ), THRB_MOUSE  (P19221    ), THRB_PIG    (Q19AZ8    ), 
THRB_PONAB  (Q5R537    ), THRB_RAT    (P18292    ), TMG1_BOVIN  (A7Z070    ), 
TMG1_HUMAN  (O14668    ), TMG1_PONAB  (Q5RCB6    ), TMG2_HUMAN  (O14669    ), 
TMG2_MOUSE  (Q8R182    ), TMG3_HUMAN  (Q9BZD7    ), TMG3_MOUSE  (Q6PAQ9    ), 
TMG4_HUMAN  (Q9BZD6    ), TMG4_MOUSE  (Q8BGN6    )
» more

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

FAXD_NOTSN  (P0CY52    ), MGP_PRIGL   (P83347    ), OSTCN_CAMHE (P86312    ), 
OSTCN_HALDD (P83473    ), THRB_SALSA  (P84122    )
» more

PDB
[Detailed view]
46 PDB

1CFH; 1CFI; 1DAN; 1IOD; 1J34; 1J35; 1MGX; 1NL0; 1NL1; 1NL2; 1P0S; 1PFX; 1Q3M; 1Q8H; 1VZM; 1W0Y; 1W2K; 1WHE; 1WHF; 1WQV; 1WSS; 1WTG; 1WUN; 1WV7; 1Z6J; 2A2Q; 2AEI; 2AER; 2B8O; 2C4F; 2EC9; 2FIR; 2PF2; 2SPT; 2ZP0; 2ZWL; 2ZZU; 3TH2; 3TH4; 4IBL; 4MZZ; 4O03; 4YLQ; 4ZMA; 5EDK; 5EDM
» more

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View entry in raw text format (no links)
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