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| Entry: PS50998 |
General information about the entry
| Entry name [info] | GLA_2 |
| Accession [info] | PS50998 |
| Entry type [info] | MATRIX |
| Date [info] | 01-JUN-2004 CREATED; 10-MAY-2017 DATA UPDATE; 05-JUL-2017 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00011 |
| Associated ProRule [info] | PRU00463 |
Name and characterization of the entry
| Description [info] | Gla domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=47; /DISJOINT: DEFINITION=PROTECT; N1=5; N2=43; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.0481772; R2=0.0159966; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2447.1208496; R2=2.4093959; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=404; H_SCORE=3421; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=279; H_SCORE=3119; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-8; D=-20; I=-20; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105; ... A B C D E F G H I K L M N P Q R S T V W Y Z /I: B1=0; BI=-105; BD=-105; /M: SY='A'; M= 31, -5,-10,-11, -5,-20, 0,-15,-15,-10,-19,-15, -1,-10, -5,-15, 24, 9, -5,-29,-20, -5; /M: SY='N'; M=-10, 40,-20, 20, 0,-20, 0, 10,-20, 0,-30,-20, 60,-20, 0, 0, 10, 0,-30,-40,-20, 0; /M: SY='S'; M= 10, 0,-10, 0, 0,-20, 0,-10,-20,-10,-30,-20, 10,-10, 0,-10, 40, 20,-10,-40,-20, 0; /M: SY='F'; M=-15,-30,-20,-35,-25, 47,-30,-20, 9,-30, 29, 9,-25,-30,-31,-20,-25,-10, 5, -4, 16,-25; /M: SY='F'; M=-12, -9,-24,-13,-11, 10,-18, -4,-10,-11, -5, -3, -5,-22, -9, -8,-11, -8,-10, -6, 6, -9; /M: SY='L'; M=-11,-20,-21,-22,-12, 13,-22,-16, 0,-17, 14, 3,-17,-23,-16, -9,-14, -5, -1,-12, 1,-13; /M: SY='E'; M= -2, 5,-26, 8, 27,-27, -4, -5,-28, 4,-21,-18, 3, -8, 8, 3, 3, -8,-24,-28,-20, 17; /M: SY='E'; M= 0, -5,-25, -3, 20,-17,-19,-11,-11, -5, -8, -9, -8, -4, 3,-10, -2, -6,-12,-26,-15, 11; /M: SY='M'; M= -5,-19,-23,-22,-15, -3,-13,-14, 0,-10, 5, 7,-14,-19,-11, -2,-12, -8, -1,-18, -5,-14; /M: SY='R'; M= -8, -1,-27, 1, 9,-22,-14, -8,-22, 12,-17,-11, -2,-13, 6, 13, -5, -7,-16,-22,-12, 7; /M: SY='P'; M= -3,-13,-28,-12, -1,-21,-19,-12,-14, 2,-10, -7,-12, 13, 2, 2, -8, -6,-16,-23,-15, -1; /M: SY='G'; M= 0, -6,-23,-10,-15,-17, 24,-16,-21,-16,-20,-14, 2,-15,-15,-16, 4, -3,-14,-24,-18,-16; /M: SY='N'; M= -8, 7,-25, 4, 0,-22,-10, -4,-19, 4,-23,-14, 14, 3, -3, -2, 1, -3,-20,-32,-17, -2; /M: SY='L'; M= -1,-12,-19,-12,-10, -7,-19,-15, 3,-18, 12, 2,-12,-17,-11,-16, -6, -2, 1,-27,-10,-11; /M: SY='E'; M=-10, -2,-34, 6, 32,-31,-20, -6,-25, 4,-24,-17, -7, 30, 15, -5, -4,-10,-30,-28,-22, 21; /M: SY='R'; M=-13,-15,-26,-16, -6,-10,-22, -7,-12, 8, 2, 0,-10,-22, 1, 31,-14, -7,-10,-19, -4, -6; /M: SY='E'; M=-10, 10,-30, 20, 60,-30,-20, 0,-30, 10,-20,-20, 0, 0, 20, 0, 0,-10,-30,-30,-20, 40; /M: SY='C'; M= -4,-15, 50,-20,-17,-18,-21,-21,-23,-16,-17,-15,-12,-22,-16,-11, -2, -4,-11,-39,-23,-18; /M: SY='M'; M=-10,-11,-23,-16, -9, -9,-24, -4, 2, -7, 4, 7, -7,-21, 1, -2,-11, -4, -2,-21, -1, -6; /M: SY='E'; M= -9, 0,-28, 5, 30,-25,-18, -2,-28, 17,-20,-15, -1, -9, 13, 26, -3, -9,-23,-25,-16, 20; /M: SY='E'; M=-10, 10,-30, 20, 60,-30,-20, 0,-30, 10,-20,-20, 0, 0, 20, 0, 0,-10,-30,-30,-20, 40; /M: SY='V'; M= -3,-19,-19,-23,-17, -5,-26,-21, 12,-10, 6, 5,-17,-21,-15,-10, -9, 1, 16,-23, -6,-17; /M: SY='C'; M=-10,-20,120,-30,-30,-20,-30,-30,-30,-30,-20,-20,-20,-40,-30,-30,-10,-10,-10,-50,-30,-30; /M: SY='E'; M= -5, 13,-23, 17, 29,-26,-12, -3,-24, 1,-23,-19, 9, -7, 8, -5, 11, 1,-21,-34,-19, 18; /M: SY='Y'; M=-13, -9,-25, -7, -9, 10,-24, -5, -5,-13, 6, -1,-13,-23,-12,-11,-16, -8, -8, -7, 17,-11; /M: SY='E'; M=-12, 12,-27, 12, 27,-14,-17, 5,-22, 2,-19,-16, 10,-11, 7, -3, -1, -7,-25,-21, -1, 16; /M: SY='E'; M=-10, -2,-29, 4, 26,-20,-21, -4,-19, 1,-14,-11, -6, 6, 6, -4, -5, -9,-20,-27,-15, 15; /M: SY='A'; M= 27, -6,-17, -9, -6,-21, -7,-18,-12,-11,-11,-11, -9, 2,-10,-19, 4, -3, -5,-24,-20, -9; /M: SY='C'; M=-14,-15, 45,-21,-16,-16,-25,-15,-28, -3,-19,-14,-11,-30,-12, 11,-10,-10,-14,-34,-18,-16; /M: SY='E'; M=-13, 18,-30, 29, 46,-32,-18, 0,-32, 9,-22,-22, 5, -4, 15, 3, -1,-10,-29,-32,-19, 30; /M: SY='V'; M= -5,-14,-23,-15, -1, -9,-25, -9, 4, -9, -1, 0,-13,-17, -5, -7, -9, -8, 5,-23, -6, -5; /M: SY='F'; M=-16,-27,-22,-32,-24, 42,-29,-10, 8,-23, 19, 13,-22,-29,-24,-17,-22,-10, 2, 2, 28,-23; /M: SY='A'; M= 16, -3,-20, -4, 16,-23,-10, -9,-16, -1,-13, -9, -6, -8, 5, -7, 4, -5,-12,-24,-18, 11; /M: SY='D'; M=-14, 23,-24, 27, 4,-19,-12, 2,-23, -4,-18,-15, 17,-16, -3, -5, 1, -3,-20,-31,-10, 0; /M: SY='B'; M= -8, 6,-23, 6, 2,-22,-16, 1,-18, 1,-18,-11, 5,-11, 3, 3, 2, 2,-13,-30,-12, 2; /M: SY='E'; M= -7, -3,-26, 0, 11,-17,-21, 5,-10, -4,-12, -7, -5,-10, 3, -8, -4, -7,-11,-22, -2, 5; /I: I=-6; MI=0; MD=-32; IM=0; DM=-32; /M: SY='G'; M= -3, -3,-28, -2, -6,-28, 26,-13,-31, -2,-25,-15, 2,-16, -6, -3, -2,-12,-23,-23,-21, -7; /M: SY='T'; M= -8,-15,-17,-23,-19, 16,-27,-19, 4,-19, 5, 0,-12,-19,-19,-16, -2, 18, 5,-15, 7,-19; /M: SY='Q'; M=-10, 0,-26, 0, 3,-21,-20, -7,-10, 4,-11, -3, -1,-12, 6, 2, -6, -5,-10,-26,-11, 4; /M: SY='E'; M= 10, -1,-22, -2, 19,-24,-14, -7,-19, 3,-15,-12, -4, -8, 11, -3, 3, -4,-16,-23,-14, 15; /M: SY='F'; M= 15,-20,-15,-30,-20, 30,-15,-19, -5,-20, 0, -5,-15,-20,-25,-20, -5, -5, 0, -5, 6,-20; /M: SY='W'; M=-20,-29,-39,-29,-25, 21,-25, -4, -9,-15, -9, -9,-29,-30,-15,-15,-29,-19,-19, 87, 56,-20; /M: SY='R'; M= -4, -5,-24, -8, -1,-21,-14, -5,-17, 8,-17, -8, 1,-12, 6, 15, 0, -2,-13,-24,-11, 1; /M: SY='R'; M= -2, -8,-24,-10, -2,-20,-15, -7,-19, 15,-17, -8, -3,-15, 2, 22, -3, -3,-11,-22,-11, -2; /M: SY='Y'; M=-20,-22,-29,-24,-22, 36,-30, 12, 2,-14, 2, 1,-20,-30,-15,-12,-20,-10, -7, 25, 70,-22; /M: SY='Y'; M=-12,-15,-23,-19,-16, 20,-23, -4, -3,-12, -2, -3,-11,-22,-14,-11, -9, -3, -4, -3, 25,-16; /M: SY='G'; M= -4, 6,-28, 10, -7,-29, 31,-12,-33,-10,-26,-19, 5,-17,-11,-10, -1,-14,-25,-25,-23, -9; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 122 in 122 different sequences |
| Number of true positive hits | 122 in 122 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 5 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | N_Hulo |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | Gla |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
122 sequences
FA101_PSETE (Q1L659 ), FA102_PSETE (Q1L658 ), FA10_BOVIN (P00743 ), FA10_CHICK (P25155 ), FA10_HUMAN (P00742 ), FA10_MOUSE (O88947 ), FA10_RABIT (O19045 ), FA10_RAT (Q63207 ), FA10_TROCA (Q4QXT9 ), FA7_BOVIN (P22457 ), FA7_HUMAN (P08709 ), FA7_MOUSE (P70375 ), FA7_PANPA (Q2F9P4 ), FA7_PANTR (Q2F9P2 ), FA7_RABIT (P98139 ), FA7_RAT (Q8K3U6 ), FA9_BOVIN (P00741 ), FA9_CANLF (P19540 ), FA9_CHICK (Q804X6 ), FA9_FELCA (Q6SA95 ), FA9_HUMAN (P00740 ), FA9_MOUSE (P16294 ), FA9_PANTR (Q95ND7 ), FA9_PIG (P16293 ), FA9_RAT (P16296 ), FAXC_OXYMI (Q58L95 ), FAXC_OXYSU (Q58L96 ), FAXC_PSETE (Q56VR3 ), FAXD1_DEMVE (A6MFK7 ), FAXD1_NOTSC (P82807 ), FAXD2_DEMVE (A6MFK8 ), FAXD2_NOTSC (Q58L94 ), FAXD_CRYNI (B5G6G5 ), FAXD_HOPST (P83370 ), FAXD_PSEPO (Q58L93 ), FAXD_TROCA (P81428 ), GAS6_HUMAN (Q14393 ), GAS6_MOUSE (Q61592 ), GAS6_RAT (Q63772 ), MGP_ARGRE (Q800Y2 ), MGP_BOVIN (P07507 ), MGP_CHICK (O42413 ), MGP_CHILA (Q6QN06 ), MGP_GALGA (P56620 ), MGP_HUMAN (P08493 ), MGP_MOUSE (P19788 ), MGP_PIG (Q8MJ39 ), MGP_PONAB (Q5RDP6 ), MGP_RABIT (P47841 ), MGP_RAT (P08494 ), OST2A_ONCMY (A0A024QYT3), OST2B_ONCMY (K9J977 ), OSTC1_DIPSG (P86867 ), OSTC1_SOLSE (Q1EG28 ), OSTC2_DIPSG (K7NTD0 ), OSTC2_MOUSE (P86547 ), OSTC2_SOLSE (P86863 ), OSTCN_ARGRE (Q800Y1 ), OSTCN_ATEGE (A2D4U1 ), OSTCN_BISPR (P83489 ), OSTCN_BOVIN (P02820 ), OSTCN_CAMBA (P86314 ), OSTCN_CAMDR (P86313 ), OSTCN_CANLF (P81455 ), OSTCN_CAPHI (P0C225 ), OSTCN_CHICK (P02822 ), OSTCN_CYPCA (Q7LZI4 ), OSTCN_DANRE (P83238 ), OSTCN_DRONO (P15504 ), OSTCN_FELCA (P02821 ), OSTCN_GORGO (P84349 ), OSTCN_HOMNE (P84351 ), OSTCN_HORSE (P83005 ), OSTCN_HUMAN (P02818 ), OSTCN_LAMGU (P86315 ), OSTCN_LEPMA (P28317 ), OSTCN_MACEU (P0C226 ), OSTCN_MACFA (P02819 ), OSTCN_MACMU (A2D670 ), OSTCN_MACNE (A2T6K4 ), OSTCN_MOUSE (P86546 ), OSTCN_PANTR (P84348 ), OSTCN_PIG (Q8HYY9 ), OSTCN_PONPY (P84350 ), OSTCN_RABIT (P39056 ), OSTCN_RAT (P04640 ), OSTCN_SPAAU (P40148 ), OSTCN_XENLA (P40147 ), OSTCN_XENTR (Q6DJ00 ), OSTCN_XIPGL (P02823 ), OSTR_MOUSE (P54615 ), PROC_BOVIN (P00745 ), PROC_CANLF (Q28278 ), PROC_HUMAN (P04070 ), PROC_MOUSE (P33587 ), PROC_PIG (Q9GLP2 ), PROC_RABIT (Q28661 ), PROC_RAT (P31394 ), PROS_BOVIN (P07224 ), PROS_HUMAN (P07225 ), PROS_MACMU (Q28520 ), PROS_MOUSE (Q08761 ), PROS_RABIT (P98118 ), PROS_RAT (P53813 ), PROZ_BOVIN (P00744 ), PROZ_HUMAN (P22891 ), PROZ_MOUSE (Q9CQW3 ), THRB_BOVIN (P00735 ), THRB_HUMAN (P00734 ), THRB_MOUSE (P19221 ), THRB_PIG (Q19AZ8 ), THRB_PONAB (Q5R537 ), THRB_RAT (P18292 ), TMG1_BOVIN (A7Z070 ), TMG1_HUMAN (O14668 ), TMG1_PONAB (Q5RCB6 ), TMG2_HUMAN (O14669 ), TMG2_MOUSE (Q8R182 ), TMG3_HUMAN (Q9BZD7 ), TMG3_MOUSE (Q6PAQ9 ), TMG4_HUMAN (Q9BZD6 ), TMG4_MOUSE (Q8BGN6 )» more
|
| UniProtKB/Swiss-Prot 'Partial' sequences |
5 sequences
FAXD_NOTSN (P0CY52 ), MGP_PRIGL (P83347 ), OSTCN_CAMHE (P86312 ), OSTCN_HALDD (P83473 ), THRB_SALSA (P84122 )» more |
| PDB [Detailed view] |
46 PDB
1CFH; 1CFI; 1DAN; 1IOD; 1J34; 1J35; 1MGX; 1NL0; 1NL1; 1NL2; 1P0S; 1PFX; 1Q3M; 1Q8H; 1VZM; 1W0Y; 1W2K; 1WHE; 1WHF; 1WQV; 1WSS; 1WTG; 1WUN; 1WV7; 1Z6J; 2A2Q; 2AEI; 2AER; 2B8O; 2C4F; 2EC9; 2FIR; 2PF2; 2SPT; 2ZP0; 2ZWL; 2ZZU; 3TH2; 3TH4; 4IBL; 4MZZ; 4O03; 4YLQ; 4ZMA; 5EDK; 5EDM » more |
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