PROSITE logo

PROSITE entry PS51039


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

Entry name [info] ZF_AN1
Accession [info] PS51039
Entry type [info] MATRIX
Date [info] 01-NOV-2004 CREATED;
02-JUN-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51039
Associated ProRule [info] PRU00449

Name and characterization of the entry

Description [info] Zinc finger AN1-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=50;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=45;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3496473; R2=0.0103997; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1313; N_SCORE=16.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=400; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-32; D=-120; I=-120; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='P';  M=  24, -74,  -6, -26, -72, -67, -64, -37,  48, -13, -58, -59,  59,  25, -10, -41,   8,  13, -78, -68;
/M: SY='K';  M= -21, -75,  47, -23, -74, -40,  34,  -6,  60, -53, -62, -26,  12,  14, -29, -23,  12,   3, -82, -64;
/M: SY='K';  M=  12, -71, -37, -48,  22, -28, -65,   4,  46,  14, -53, -12,  -5, -57,   0,  12,  19, -16, -72, -58;
/M: SY='K';  M= -24, -74,  12, -53, -77,  42, -62, -73,  55, -75, -22, -28,  20,  -6,   7,  11,  22, -26, -78, -69;
/M: SY='N';  M= -14, -72, -50, -31, -18, -36,  26, -70,  40, -72, -63,  80,   1,  -5,  13,   3, -37, -20, -75,  21;
/M: SY='H';  M= -31, -78, -59, -51, -74, -42,  87, -79,  35, -73, -61, -50, -22, -12,  80, -29,  17, -74, -81, -56;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/M: SY='S';  M=  21,   5, -26, -16,  27, -25, -28, -66, -20, -21, -62,  -6,  34,   6, -63,  61, -19, -48, -72,  -7;
/I:         I=-31; MD=-65;
/M: SY='F';  M= -76, -24, -41,   0,  47, -94,   0, -19, -16, -17,   4, -82, -90, -77,  -3, -80, -73,  39, -80, -16; D=-31;
/I:         I=-31; MD=-65;
/M: SY='P';  M= -25,-102,  -1,   6,-105, -57, -85, -99,  23,-102, -93, -78,  54, -33, -76, -14, -19, -96,-103, -96; D=-31;
/I:         I=-31; MI=-65; MD=-65; IM=-65; DM=-65;
/M: SY='T';  M=   5, -79,  28, -61, -82,  18,   2, -80,   4, -81, -74, -56, -74, -17,  23,  14,  42, -53, -88, -28; D=-31;
/I:         I=-31; DM=-65;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/M: SY='R';  M= -34, -76, -56, -50, -77,  -1, -55, -78,  51, -76, -65,  30, -13,  21,  73,   3,  13, -73, -77, -66;
/M: SY='K';  M= -18, -77, -23,  29, -76, -70, -57, -47,  64, -32, -61, -53, -65,  59,  39, -21,  -3, -15, -76, -65;
/M: SY='K';  M= -29, -74, -65, -56, -62, -43, -61,  11,  57,  23,   5, -58, -71, -51,  52,  12,  -5, -31, -73, -15;
/M: SY='D';  M= -28, -71,  58,  40, -63, -75, -66, -43, -61,  14, -53, -58, -69, -59, -66, -58,  24,  57, -86, -65;
/M: SY='F';  M= -57, -71, -68, -22,  65,  58, -66, -60, -67,  -9,  39, -58, -71, -67, -71,  -2,  43, -60, -64, -49;
/M: SY='L';  M= -65, -69, -80, -74,  32, -83, -69,   3, -28,  70,  24, -76, -79, -69, -23, -70,   8,  12, -69, -50;
/M: SY='P';  M=   4, -72, -66, -22, -17, -68, -65, -54,   0,  21,  37, -62,  65,   5, -63,  11,  41, -21, -76, -63;
/I:         I=-29; MD=-61;
/M: SY='G';  M= -36, -96, -80, -90,-101,  62, -85, -38, -85,-101, -91,  31, -91,  -9, -91, -47, -47, -96,-100, -96; D=-29;
/I:         I=-29; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='F';  M= -66, -72, -80, -75,  92,   3, -68,  21, -72,   8,  -1, -71, -79,  20, -72, -31, -63,   9, -54, -15;
/M: SY='K';  M= -22, -73,   6,  20,  12, -35,  15,  -3,  43, -64, -33,  18, -10, -34,  11,  -9,  31,  -2, -77, -60;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/I:         I=-36; MD=-77;
/M: SY='D';  M= -26, -97,  58, -42, -97, -85, -76, -91,  -1, -47,  20, -16,  16,  -3, -12, -39, -77, -90,-105, -87; D=-36;
/I:         I=-36; MI=-77; IM=-77; DM=-77;
/M: SY='R';  M=  -7, -78,  15, -53,   0,   7,  43, -74,   1, -29, -61, -10, -73,   8,  80, -58, -63, -71, -71,  21;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/M: SY='G';  M= -52, -73, -32, -11, -78,  70,  19, -80,  28, -43, -69,  28, -67, -17, -58,  34, -25, -76, -78, -69;
/M: SY='G';  M=  -9, -74, -57,  -6, -39,  45,  41, -36,  11, -30, -61,  33, -69,  30,  14,   6, -34, -20, -75,  -2;
/M: SY='N';  M= -60, -71,  24, -27, -64, -69,   4,   0,  -9,  -3,  28,  59, -71, -18,  21, -26,  25,  30, -85, -62;
/M: SY='F';  M= -74, -73, -81, -79, 110, -81,  33, -51, -75, -44, -50, -73, -84, -79, -71, -71, -67, -29, -40,  63;
/M: SY='C';  M= -62, 152, -81, -81, -30, -77, -79, -77, -77, -68, -68, -67, -92, -84, -83, -64, -61, -66, -94, -14;
/M: SY='L';  M=  21, -70, -73, -70, -57,  43, -68,  19, -20,  48,  28, -64, -41, -64, -70,   8, -59, -48, -74, -62;
/M: SY='K';  M=  15, -72,  23,  30, -74, -45, -58, -68,  48, -21, -11, -18, -65,  17,   3,  30,   5, -31, -79, -66;
/M: SY='H';  M= -69, -81, -53, -53, -68, -71, 149, -86, -58, -68, -54, -43, -70, -47, -52, -59, -68, -86,-103, -37;
/M: SY='R';  M= -30, -81, -64, -53, -12, -75,  38, -76,   0, -71, -62, -57,  -8, -43, 105, -61, -64, -29, -76, -58;
/M: SY='Y';  M= -28,   9, -69, -35,  48, -37,  67, -55, -67,  29, -48, -63, -50, -62, -66,  15, -19, -58, -54,  76;
/M: SY='P';  M=  11, -78, -64,  -6, -60,  -6, -58, -66, -17, -31,  26, -63,  82,   4, -37,  15, -43, -66, -64,  58;
/M: SY='E';  M=  -3, -76,  39,  69, -17, -24, -59, -69, -13,  -9,  -1, -55,  14, -47,  -2,  -6,   5, -50, -79, -66;
/M: SY='D';  M= -18, -76,  75,   3, -77, -39, -20,   3,  14, -71, -66,  23, -67,  37,  -6,   7, -11, -21, -86, -66;
/M: SY='H';  M= -27, -80, -54, -54, -65, -70, 146, -84, -58, -68, -54, -44, -70, -48, -53, -58, -67, -83, -96,   3;
/M: SY='D';  M=   0, -74,  49,  16, -79,  32,  26, -78,  36, -77, -69,  18, -66, -23, -10,  21, -24, -40, -83, -67;
/M: SY='C';  M= -27, 151, -81, -80, -70, -76, -80, -75, -76, -31, -66, -68, -91, -83, -82, -63, -61, -64, -99, -80;
/M: SY='P';  M=  -1, -74, -59, -10, -76,  23, -63, -71,  -5, -75, -67,   5,  61,  11,  -7,  38,  29, -31,  36, -68;
/M: SY='F';  M= -16, -75, -62,  16,  62,  37,  -3, -66,  18, -29, -60,  -5, -14, -59, -28,  -7, -29, -66,  17,  35;
/M: SY='D';  M=  14, -76,  65, -12, -73,  -3, -60, -32,  18,   5, -62,  -8,  23, -54,  27, -34, -58, -29, -82, -67;
/M: SY='Y';  M=   3, -74, -19,  16,  44, -10,  10, -14, -30, -15, -55,  -1, -15, -59,  -8, -12,  -8, -26, -56,  71;
/M: SY='K';  M= -12, -76, -25, -24, -72, -69,  32,   2,  62, -65,   8, -10, -68,  44,  40,   7, -56,  -3, -77, -61;
/M: SY='P';  M=  19,   5, -62, -14, -73,  27,  -8,   2,  22, -23, -61, -20,  43,  12, -11,  19,  -9, -41, -77, -68;
/M: SY='A';  M=  38, -72,  34,  18, -75, -36,  37, -36,  12, -69, -22,   1,   6, -51,  21,  -9,  13, -11, -83, -65;
/M: SY='A';  M=  43, -70, -41,   8, -27,  38, -66,  -7, -23, -35, -61, -18,  -1, -57,   7,  27, -55,   1, -76, -67;
/I:         E1=0; IE=-255; DE=-255;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_06 which contains 572'619 sequence entries.


Total number of hits 80 in 64 different sequences
Number of true positive hits 80 in 64 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] ZN_FING
Feature description [info] AN1-type
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
64 sequences

CUZ1_YEAST  (P53899), SAP10_ARATH (Q9STJ9), SAP10_ORYSJ (Q69LE0), 
SAP11_ARATH (Q8VZ42), SAP11_ORYSJ (Q84PD8), SAP12_ARATH (Q67YE6), 
SAP12_ORYSJ (Q6Z541), SAP13_ARATH (Q9SCM4), SAP13_ORYSJ (Q5JLA7), 
SAP14_ORYSJ (Q852K8), SAP15_ORYSJ (Q0DJC7), SAP16_ORYSJ (Q0D5B9), 
SAP17_ORYSJ (Q6H595), SAP1_ARATH  (Q6NNI8), SAP1_ORYSI  (A2Z2J6), 
SAP1_ORYSJ  (A3C039), SAP2_ARATH  (Q8H0X0), SAP2_ORYSJ  (Q942F8), 
SAP3_ARATH  (Q9ZNU9), SAP3_ORYSJ  (Q5JN07), SAP4_ARATH  (Q9SJM6), 
SAP4_ORYSJ  (Q6H7P8), SAP5_ARATH  (Q9LHJ8), SAP5_ORYSJ  (Q6H754), 
SAP6_ARATH  (Q94B40), SAP6_ORYSJ  (Q852K5), SAP7_ARATH  (Q9SZ69), 
SAP7_ORYSJ  (Q852K6), SAP8_ARATH  (Q3EA33), SAP8_ORYSI  (A2YEZ6), 
SAP8_ORYSJ  (A3BDI8), SAP9_ARATH  (O49663), SAP9_ORYSJ  (Q7Y1W9), 
SMBP2_HUMAN (P38935), SMBP2_MESAU (Q60560), SMBP2_MOUSE (P40694), 
SMBP2_RAT   (Q9EQN5), TMC1_YEAST  (Q08422), Y8260_DICDI (Q55GW8), 
YHM5_SCHPO  (O94338), ZFAN1_HUMAN (Q8TCF1), ZFAN1_MOUSE (Q8BFR6), 
ZFAN3_HUMAN (Q9H8U3), ZFAN3_MOUSE (Q497H0), ZFAN3_RAT   (Q5U2M7), 
ZFAN3_XENLA (Q66J85), ZFAN4_HUMAN (Q86XD8), ZFAN4_MOUSE (D3Z3C6), 
ZFAN5_HUMAN (O76080), ZFAN5_MOUSE (O88878), ZFAN5_RAT   (B5DF11), 
ZFAN6_BOVIN (Q3SZY7), ZFAN6_HUMAN (Q6FIF0), ZFAN6_MOUSE (Q9DCH6), 
ZFAN6_PONAB (Q5R7S6), ZFAN6_RAT   (Q6DGF4), ZFAND_DICDI (Q55BU1), 
ZFN2A_HUMAN (Q8N6M9), ZFN2A_MOUSE (Q9JII7), ZFN2A_PONAB (Q5R966), 
ZFN2A_RAT   (Q5U2P3), ZFN2B_HUMAN (Q8WV99), ZFN2B_MOUSE (Q91X58), 
ZFN2B_RAT   (Q4KLG9)
» more

PDB
[Detailed view]
13 PDB

1WFE; 1WFF; 1WFH; 1WFL; 1WFP; 1WG2; 1WYS; 1X4V; 1X4W; 5IJ4; 7QXW; 7Y7L; 7YAB
» more