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Entry: PS51039

General information about the entry

Entry name [info] ZF_AN1
Accession [info] PS51039
Entry type [info] MATRIX
Date [info] 01-NOV-2004 CREATED; 01-OCT-2013 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC51039
Associated ProRule [info] PRU00449

Name and characterization of the entry

Description [info] Zinc finger AN1-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=44;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=40;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.7740248; R2=0.0057708; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=1253; N_SCORE=8.0; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=1062; N_SCORE=6.9; MODE=1; TEXT='RR';
/DEFAULT: M0=-7; D=-20; I=-20; B1=-300; E1=-300; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='K'; M=  7, -1,-26,  1, -1,-13,-13,-14, -8, 10, -7,  6, -1, -5, -5, -3,  1,  2, -4,-31,-11, -5;
/M: SY='N'; M=  5,  7, -8, -3, -4,-14, -9,-13, -7,  2,-12,  1, 21,-11, -1, -4,  2,  5,-10,-42,-26, -5;
/M: SY='R'; M= -4, -6,-21, -2, -5,-13,-17,-10,-20,  7,-13,  2, -5, -7, 12, 32, -1, -8, -9,-20, -5, -2;
/M: SY='C'; M=-29,-21,158,-31,  7,-22,-39,-49,-19,-29,  1,-20,-10,-31,-21,-19,-19,-20,-18,-18,-55, -2;
/M: SY='D'; M= -2,  2,-29,  3, -4, -9,  2, -3,-14, -2, -8,-10,  0, -6, -9,-12, -1, -9,-15,-23,-11, -8;
/M: SY='V'; M=  0,-13,-25,-17,-14,  5,-12,-19,  3, -4, -1, -3, -9,-18, -6, -5, -1,  2,  6,-12,  1,-12;
/M: SY='C'; M=-23,-18,137,-26, 10,-29,-34,-44,-19,-23, -3,-17,-10,-20,-16,-17,-17,-17,-19,-22,-54,  1;
/M: SY='R'; M= -3, -4,-27, -7, -5,-10,  9,-18,-17, 10,-18, -2,  1, -8,  4, 19, -2,-16,-18,-10,-13, -4;
/M: SY='K'; M= -2, -6,  6, -7, 13,-17,-17,-22,-19, 16,-14,  7, -4, -1,  6,  8, -3, -7,-16,-21,-19,  9;
/M: SY='K'; M= -1, -6,-25, -3, 11,-13,-14,-16,-21, 26,-18, 10, -5,  3, 12, 25, -1,-11,-16,-16, -8,  9;
/M: SY='V'; M=  6,-10,-12,-12,-10, -2,-22,-19, 18,-12, 11,  4,-11,-22,-13,-17, -5, 10, 20,-30,  3, -9;
/M: SY='G'; M= -1,  1,-32, -5, -8,-22, 34,-21, -9,  0,-15,-11,  2, -3,-12,-14,  1, -9,-20, -8,-19,-11;
/M: SY='L'; M= -2,-12, -8,-16,-15, 10,-19,-13, 25,-16, 28, 17,-14,-29,-18,-19,-14,  4, 18,-26, 15,-14;
/I:         I=-4; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='T'; M=  6, -6,-13,-11,-10, -9,-17,-12,  9, -6,  8,  8, -2,-13, -6,-17,  2, 18, 11,-31, -3, -7; D=-4;
/I:         I=-4; DM=-22;
/M: SY='G'; M=  0,  0,-32, -8,-11,-29, 45,-18,-12, -4,-19,-17,  3,  7,-13,-18,  0, -9,-27,-10,-27,-13;
/M: SY='F'; M=-13,-21,-28,-30,-21, 43,-24,-17,  1, -6, 15, -5,-12,-26, -9, -6,-10, -8,  5,  0, 24,-19;
/I:         I=-6; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='Q'; M=  1, -1,-22,  2,  5,-12,-16, -6,-14,  6, -9, -2, -4, -4,  7,  2,  0, -2,-12,-24, -6,  4;
/M: SY='C'; M=-30,-20,170,-30, 10,-30,-40,-50,-20,-30,  0,-20,-10,-30,-20,-20,-20,-20,-20,-20,-60,  0;
/M: SY='R'; M= -3, -8,-22, -6,  1,-13,-15, -6,-22, 12,-20,  1, -5, -6, 21, 40, -1,-13,-16,-15, -8,  4;
/I:         I=-6; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='C'; M=-30,-20,170,-30, 10,-30,-40,-50,-20,-30,  0,-20,-10,-30,-20,-20,-20,-20,-20,-20,-60,  0;
/M: SY='G'; M=  1,  2,-31, -4, -8,-22, 45,-23,-11, -2,-16,-13,  2, -9,-14,-15,  5,-11,-23, -5,-23,-12;
/M: SY='N'; M= -2, -1,-29, -4, -8,-12,  3,  0,-10,  0,-10,  0,  5,-14, -6, -1, -2, -8,-12,-22,-11, -9;
/M: SY='V'; M= -3,-13,-20,-14,-16,  0,-21,-14,  9, -6,  9,  8,-10,-20, -7,  0, -7,  5, 13,-21,  9,-13;
/M: SY='F'; M=-24,-29,-35,-38,-33, 78,-29,-21, -1,-11, 24,-15,-18,-35,-25, -8,-13,-16, 10, 18, 45,-33;
/M: SY='C'; M=-30,-20,170,-30, 10,-30,-40,-50,-20,-30,  0,-20,-10,-30,-20,-20,-20,-20,-20,-20,-60,  0;
/M: SY='G'; M=  5, -5,-23, -8, -8, -5,  9,-16, -2, -3, -1, -2, -4,-18,-11,-13,  2, -4, -6,-17,-12,-11;
/M: SY='K'; M=  4,  0,-20,  3,  6,-15,-12,-15,-12,  9, -8,  2, -4, -5,  3,  1,  4,  1, -7,-25, -9,  4;
/M: SY='H'; M=-20,-20,-50,-20,  0,-30,-30,140,-20,-20,-10, 20,-10, 10,  0,-10,-10,-20,-30,-50,  0,  0;
/M: SY='R'; M= -9,-18,-23,-11,-10,-12,-14, -2,-23,  5,-18,  0,-16,-10, 21, 59, -7,-25,-10, -6, -3, -3;
/M: SY='Y'; M=-25,-21,-33,-14,-16, 28,-26,  3,  2,-15, 30,  3,-27,-24,-15,-10,-18, -8,  7, 11, 54,-16;
/M: SY='P'; M=  1,-12,-29, -5,  5,-27, -8,  0,-20,  8,-20,-20,-17, 54, -1, -8,  0,  4,-22,-29,-17, -2;
/M: SY='E'; M=  2, 10, -9, 22, 32,-37,-12, -8,-26, 12,-12,-13, -2, 10,  8,-10,  2, -9,-23,-24,-19, 24;
/M: SY='N'; M=  7,  5,-22,  3,  1,-17,-10,-16, -2,  4, -9,  1,  9,-12,  5, -3,  0,  0, -4,-33,-17,  0;
/M: SY='H'; M=-20,-20,-50,-20,  0,-30,-30,140,-20,-20,-10, 20,-10, 10,  0,-10,-10,-20,-30,-50,  0,  0;
/M: SY='D'; M=  3, 17,-25, 22, -3,-21,  7,-20,-15, -3,-11,-17, 11,-14,-11,-14,  5, -3,-13,-28,-17, -8;
/M: SY='C'; M=-30,-20,170,-30, 10,-30,-40,-50,-20,-30,  0,-20,-10,-30,-20,-20,-20,-20,-20,-20,-60,  0;
/M: SY='P'; M=  3, -2,-27, -3, -7,-25, 11,-13,-11, -3,-17,-19, -2, 19, -9,-16,  8,  8,-16,-27,-20,-10;
/I:         I=-5; MD=-27;
/M: SY='F'; M=-10,-15,-25,-18, -8, 25,-12,-15, -6, -1,  7, -9,-11,-16,-10, -8, -6,-13, -1,  5, 15,-10; D=-5;
/I:         I=-5; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='D'; M=  2, 26,-24, 47, 10,-38, -2,-17,-29,  4,-12,-18,  5, -7, -3, -5,  1,-10,-19,-29,-15,  4;
/M: SY='Y'; M=-19,-23,-38,-19,-19, 24,-22, -9,  4,-10, 18, -2,-24,-23,-13, -8,-14, -9, 11, 18, 42,-19;
/M: SY='K'; M= -2,-10,-24, -9,  7,-10,-14,-14,-12, 19,-13, 11, -9, -4,  6, 17, -6,-12,-10, -9, -4,  4;
/M: SY='A'; M= 10,  1,-21, -4, -4,-16, -3,-15, -5, -1,-13, -3,  8,-13,  7,  2,  4,  4, -5,-32,-21, -2;
/M: SY='H'; M=  0, -5,-29, -1, -1,-17,-13,  5,-10,  0, -7,  4, -6, -9, -3, -5, -2, -5, -7,-17, -5, -3;
/M: SY='G'; M=  8, -3,-28, -4,  2,-30, 30,-13,-13, -1,-17,-12, -5,  6, -4,-14,  2,-10,-21,-14,-28, -1;
/I:         E1=0; IE=-105; DE=-105;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 78 in 62 different sequences
Number of true positive hits 78 in 62 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.50 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] N_Hulo
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Feature key [info] ZN_FING
Feature description [info] AN1-type
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
62 sequences

CUZ1_YEAST  (P53899    ), SAP10_ARATH (Q9STJ9    ), SAP10_ORYSJ (Q69LE0    ), 
SAP11_ARATH (Q8VZ42    ), SAP11_ORYSJ (Q84PD8    ), SAP12_ARATH (Q67YE6    ), 
SAP12_ORYSJ (Q6Z541    ), SAP13_ARATH (Q9SCM4    ), SAP13_ORYSJ (Q5JLA7    ), 
SAP14_ORYSJ (Q852K8    ), SAP15_ORYSJ (Q0DJC7    ), SAP16_ORYSJ (Q0D5B9    ), 
SAP17_ORYSJ (Q6H595    ), SAP1_ARATH  (Q6NNI8    ), SAP1_ORYSI  (A2Z2J6    ), 
SAP1_ORYSJ  (A3C039    ), SAP2_ARATH  (Q8H0X0    ), SAP2_ORYSJ  (Q942F8    ), 
SAP3_ARATH  (Q9ZNU9    ), SAP3_ORYSJ  (Q5JN07    ), SAP4_ARATH  (Q9SJM6    ), 
SAP4_ORYSJ  (Q6H7P8    ), SAP5_ARATH  (Q9LHJ8    ), SAP5_ORYSJ  (Q6H754    ), 
SAP6_ARATH  (Q94B40    ), SAP6_ORYSJ  (Q852K5    ), SAP7_ARATH  (Q9SZ69    ), 
SAP7_ORYSJ  (Q852K6    ), SAP8_ARATH  (Q3EA33    ), SAP8_ORYSI  (A2YEZ6    ), 
SAP8_ORYSJ  (A3BDI8    ), SAP9_ARATH  (O49663    ), SAP9_ORYSJ  (Q7Y1W9    ), 
SMBP2_HUMAN (P38935    ), SMBP2_MESAU (Q60560    ), SMBP2_RAT   (Q9EQN5    ), 
TMC1_YEAST  (Q08422    ), Y8260_DICDI (Q55GW8    ), ZFAN1_HUMAN (Q8TCF1    ), 
ZFAN1_MOUSE (Q8BFR6    ), ZFAN3_HUMAN (Q9H8U3    ), ZFAN3_MOUSE (Q497H0    ), 
ZFAN3_RAT   (Q5U2M7    ), ZFAN3_XENLA (Q66J85    ), ZFAN4_HUMAN (Q86XD8    ), 
ZFAN4_MOUSE (D3Z3C6    ), ZFAN5_HUMAN (O76080    ), ZFAN5_MOUSE (O88878    ), 
ZFAN5_RAT   (B5DF11    ), ZFAN6_BOVIN (Q3SZY7    ), ZFAN6_HUMAN (Q6FIF0    ), 
ZFAN6_MOUSE (Q9DCH6    ), ZFAN6_PONAB (Q5R7S6    ), ZFAN6_RAT   (Q6DGF4    ), 
ZFAND_DICDI (Q55BU1    ), ZFN2A_HUMAN (Q8N6M9    ), ZFN2A_MOUSE (Q9JII7    ), 
ZFN2A_PONAB (Q5R966    ), ZFN2A_RAT   (Q5U2P3    ), ZFN2B_HUMAN (Q8WV99    ), 
ZFN2B_MOUSE (Q91X58    ), ZFN2B_RAT   (Q4KLG9    )
» more

UniProtKB/Swiss-Prot
False negative sequences
2 sequences

SMBP2_MOUSE (P40694    ), YHM5_SCHPO  (O94338    )

		
PDB
[Detailed view]
7 PDB

1WFH; 1WFL; 1WFP; 1WG2; 1X4V; 1X4W; 5IJ4

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