Entry: PS51090

Forthcoming changes to the profile format
General information about the entry

Entry name [info] CORTACTIN
Accession [info] PS51090
Entry type [info] MATRIX
Date [info] MAR-2005 (CREATED); OCT-2013 (DATA UPDATE); MAR-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC51090
Associated ProRule [info] PRU00413

Name and characterization of the entry

Description [info] Cortactin repeat profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=37;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=37;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.8901668; R2=0.0124620; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=409.37061; R2=14.11821; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=611; N_SCORE=8.5; H_SCORE=7892; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=446; N_SCORE=6.4; H_SCORE=6198; MODE=1; TEXT='RR';
/DEFAULT: M0=-8; D=-20; I=-20; B1=*; E1=*; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='Y'; M=  6,-14,-21,-17,-14,  8,-17,  3, -6,-10, -7, -6,-13,-21, -9,-13, -3, -3, -7,  5, 35,-14;
/M: SY='S'; M=  9,-11,-13,-12, -9,-15,-13,-18, -5, -3,-15, -8, -7,-16, -9, -8, 12,  6,  8,-31,-15, -9;
/M: SY='R'; M=-14, -3,-27, -5,  1,-21,-20, 12,-27, 22,-21, -8,  2,-15,  7, 32, -5, -2,-19,-23, -5,  1;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='F'; M=-20,-28,-22,-36,-28, 71,-30,-13,  0,-26,  8,  0,-20,-30,-35,-18,-20,-10, -2, 14, 39,-28;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='K'; M=-12, -2,-30, -2,  8,-28,-20, -8,-30, 46,-28,-10,  0,-12, 10, 38,-10,-10,-20,-20,-10,  8;
/M: SY='F'; M=-20,-27,-23,-33,-27, 63,-30, -6,  0,-23,  7,  0,-20,-30,-30,-17,-20,-10, -3, 17, 47,-27;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='V'; M=  0,-30,-10,-30,-30,  0,-30,-30, 30,-20, 10, 10,-30,-30,-30,-20,-10,  0, 50,-30,-10,-30;
/M: SY='E'; M=-10,  5,-30, 10, 41,-35,-20,  5,-25, 10,-20,-10,  0, -5, 39,  5,  0,-10,-30,-25,-15, 40;
/M: SY='R'; M= -6, -4,-22, -7,  1,-21,-17, -6,-16, 12,-17,  0, -1,-13, 12, 13,  4,  6,-13,-25,-10,  6;
/M: SY='D'; M=-18, 43,-30, 62, 27,-38,-12,  0,-38,  2,-28,-28, 17, -8,  3, -8,  0,-10,-30,-38,-20, 15;
/M: SY='R'; M=-18, -8,-30, -8,  2,-22,-20, -2,-30, 34,-22,-10,  0,-18, 10, 62,-10,-10,-20,-20,-10,  2;
/M: SY='W'; M= -3,-17,-27,-21, -8,-14,-19,-10, -5, -7, -7,  7,-17,-19, 11, -8,-12,-12, -8, 14, -1,  2;
/M: SY='D'; M=-20, 50,-30, 70, 20,-40,-10,  0,-40,  0,-30,-30, 20,-10,  0,-10,  0,-10,-30,-40,-20, 10;
/M: SY='K'; M= -7,  0,-27,  0, 10,-30,-17, -7,-27, 35,-29,-10,  2,-10, 15, 21,  0, -5,-20,-23,-12, 12;
/M: SY='A'; M= 21, -7, 13,-13, -9,-20, -5,-17,-18,-14,-21,-16, -3,-15, -9,-17, 20,  7, -6,-34,-22, -9;
/M: SY='A'; M= 50,-10,-10,-20,-10,-20,  0,-20,-10,-10,-10,-10,-10,-10,-10,-20, 10,  0,  0,-20,-20,-10;
/M: SY='V'; M= -4,-30,-14,-30,-26,  4,-30,-26, 26,-24, 26, 14,-30,-30,-26,-20,-18, -4, 34,-26, -6,-26;
/M: SY='G'; M=  0,-10,-30,-10,-20,-30, 70,-20,-40,-20,-30,-20,  0,-20,-20,-20,  0,-20,-30,-20,-30,-20;
/M: SY='F'; M=-20,-24,-29,-29,-22, 39,-26,  8, -9,-20, -3, -4,-18,-28,-21,-14,-22,-15,-13, 32, 39,-21;
/I:         E1=0; IE=-105; DE=-105;
/M: SY='D'; M=-17, 37,-30, 54, 33,-37,-13,  0,-37,  3,-27,-27, 14, -7,  6, -7,  0,-10,-30,-37,-20, 19;
/M: SY='Y'; M=-20,-16,-30,-16,-16, 21,-28, 34, -5,-10, -4,  0,-15,-28, -6, -8,-18,-12,-14, 19, 69,-16;
/M: SY='Q'; M=-10,  0,-30,  0, 15,-35,-20,  0,-25, 30,-25, -5,  0,-10, 35, 20, -5,-10,-25,-20,-10, 25;
/M: SY='G'; M= -2, -1,-26,  2, 11,-28, 27,-11,-33, -8,-27,-20,  2,-11, -3,-11,  7, -9,-26,-27,-25,  4;
/M: SY='K'; M=-10,  3,-30,  7, 27,-30,-20, -7,-30, 36,-27,-13,  0, -7, 13, 20, -7,-10,-23,-23,-13, 20;
/M: SY='L'; M= -5,-20,-15,-23,-18,  2,-27,-21, 11,-22, 24,  8,-20,-23,-18,-17,-10, 12, 12,-25, -5,-18;
/M: SY='E'; M=  3,  3,-23,  6, 31,-28,-13, -3,-23,  3,-20,-15,  0, -5, 19, -3,  9, -3,-21,-28,-18, 25;
/M: SY='K'; M=-10, -5,-28, -5,  5,-23,-22,-12,-21, 36,-16, -5, -5,-14,  5, 21,-14,-10,-15,-20, -8,  5;
/M: SY='H'; M=-20,  0,-30,  0,  0,-20,-20,100,-30,-10,-20,  0, 10,-20, 10,  0,-10,-20,-30,-30, 20,  0;
/M: SY='E'; M= -1,  1,  2,  2, 25,-24,-19,-11,-25, -3,-17,-17, -5,-10,  3, -9,  2, -1,-18,-32,-20, 14;
/M: SY='S'; M= 10,  0,-10,  0,  0,-20,  0,-10,-20,-10,-30,-20, 10,-10,  0,-10, 40, 20,-10,-40,-20,  0;
/M: SY='Q'; M=-10,  0,-30,  0, 20,-40,-20, 10,-20, 10,-20,  0,  0,-10, 60, 10,  0,-10,-30,-20,-10, 40;
/M: SY='K'; M=-10, -8,-26, -8,  2,-24,-22, -8,-18, 27,-19, -5, -5,-16, 11, 26, -8, -8, -9,-22,-10,  6;
/M: SY='D'; M=-20, 50,-30, 70, 20,-40,-10,  0,-40,  0,-30,-30, 20,-10,  0,-10,  0,-10,-30,-40,-20, 10;
/I:         E1=0; IE=-105; DE=-105;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_04 which contains 544'996 sequence entries.


Total number of hits 29 in 5 different sequences
Number of true positive hits 29 in 5 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] PS_Langendijk_Genevaux
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 7
Feature key [info] REPEAT
Feature description [info] Cortactin
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
5 sequences

HCLS1_HUMAN (P14317), HCLS1_MOUSE (P49710), SRC8_CHICK  (Q01406), 
SRC8_HUMAN  (Q14247), SRC8_MOUSE  (Q60598)
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