PROSITE entry PS51198
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General information about the entry
| Entry name [info] | UVRD_HELICASE_ATP_BIND |
| Accession [info] | PS51198 |
| Entry type [info] | MATRIX |
| Date [info] |
01-JUN-2006 CREATED;
10-MAY-2017 DATA UPDATE; 27-MAR-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51198 |
| Associated ProRule [info] | PRU00560 |
Name and characterization of the entry
| Description [info] | UvrD-like DNA helicase ATP-binding domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=290; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=285; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8038350; R2=0.0041334; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=75402.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 0.5%'; /CUT_OFF: LEVEL=0; SCORE=3193; H_SCORE=75402; N_SCORE=15.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=1137; H_SCORE=75402; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-16; D=-50; I=-50; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='S'; M= 1, -55, 9, 18, 4, -16, 7, -11, 3, -11, 15, -1, 16, 1, -14, 21, 5, -11, -46, -27; /M: SY='P'; M= -9, -56, 5, -7, -17, 8, 6, -12, 0, 11, 10, 15, 19, 14, -7, 5, 8, -32, -1, -24; /M: SY='L'; M= -23, -49, 6, -23, -4, -28, 16, -26, -16, 50, -20, -6, 26, -22, -27, -6, -18, -30, 40, -13; /M: SY='N'; M= -15, -53, 30, -11, -43, -38, -38, -33, -24, -13, -40, 69, 17, -11, -10, 3, 40, -23, -54, -44; /M: SY='P'; M= 1, -27, 29, 33, -23, -31, -32, -35, 3, -35, -49, 2, 57, 18, -19, 2, 12, -44, -29, -51; /M: SY='Q'; M= 14, -56, 10, 48, -31, -28, -16, -50, -1, -41, -47, -16, 15, 66, -1, 2, -33, -37, -59, -25; /M: SY='Q'; M= -20, -64, -17, 7, -41, -34, -14, -30, -5, -26, -30, -24, -43, 103, 25, -29, -29, -49, -38, -26; /M: SY='Q'; M= 5, -45, -7, 4, -24, -42, -26, -19, 23, -9, -19, -17, -22, 54, 52, -18, -30, -32, 20, -19; /M: SY='E'; M= 28, -39, -13, 40, -37, -33, -22, -6, 5, -1, -36, -12, -16, 29, 16, -12, -25, -8, -42, -31; /M: SY='A'; M= 60, -36, -27, -28, -23, -35, -46, 17, -34, -6, -14, -45, -20, -20, -22, -17, -24, 31, -59, -38; /M: SY='V'; M= 29, -22, -20, -24, -37, -48, -38, 35, -40, -13, -20, -8, -44, -20, -11, -28, 3, 54, -62, -21; /M: SY='T'; M= 2, -14, 4, 10, -5, -31, -13, -10, -4, 5, -26, -4, 8, -1, 2, -2, 30, -1, 0, -6; /M: SY='H'; M= 17, -17, 29, -2, -29, -29, 58, -40, -22, -21, -38, 1, 22, -7, -3, 8, 15, -36, 20, 8; /M: SY='P'; M= -21, -32, 4, 3, -13, -11, 2, -5, -20, 6, -20, 3, 49, 5, 6, -2, 6, -6, -5, -18; /M: SY='D'; M= -3, -37, 35, 21, -36, 14, 15, -43, -5, -23, -43, 22, -3, 10, 7, 17, 1, -42, -16, -34; /M: SY='G'; M= -13, -27, 5, -11, -57, 71, -9, -54, -1, -43, -52, -8, -21, 6, -2, -3, -8, -42, -60, -43; /M: SY='P'; M= -13, -27, -8, -28, -43, -40, 52, -33, -13, -37, -31, 30, 75, -9, -16, 21, 7, -28, -66, -37; /M: SY='V'; M= 5, 13, -48, -53, 0, -52, -15, 17, -46, 36, 19, 3, -60, -22, -9, -22, -13, 38, -35, -15; /M: SY='L'; M= -14, 6, -54, -53, 1, -52, -44, 1, -32, 60, 12, -52, -63, -3, 9, -39, -40, 7, 30, -13; /M: SY='V'; M= -36, -34, -67, -62, -30, -69, -66, 56, -59, 13, -19, -61, -61, -59, -61, -52, -36, 75, -64, -36; /M: SY='L'; M= -5, -42, -36, 22, -23, -45, -35, 25, -21, 36, -12, -16, -40, -10, -31, 15, -3, 13, -59, -24; /M: SY='A'; M= 86, -46, -50, -45, -59, 22, -52, -51, -46, -52, -46, -43, -49, -43, -51, -15, -36, -38, -58, -55; /M: SY='G'; M= 2, 27, -47, -53, -59, 74, -52, -44, -49, -51, -51, -5, -6, -46, -56, 33, -40, -3, -61, -56; /M: SY='A'; M= 76, -52, -50, -41, -62, -37, -52, -50, -37, -55, -47, -48, 74, -44, -52, -30, -37, -39, -60, -58; /M: SY='G'; M= -64,-119, -94,-118,-132, 196,-108,-147,-105,-138,-116, -66,-102,-100,-120, -64,-102,-134,-113,-122; /M: SY='S'; M= 13, -9, -81, -83,-108, -66, -92, -99, -81,-107, -97, -59, -91, -75, -93, 150, 137, -79,-133, -86; /M: SY='G'; M= -64,-119, -94,-118,-132, 196,-108,-147,-105,-138,-116, -66,-102,-100,-120, -64,-102,-134,-113,-122; /M: SY='K'; M= -91,-120, -76, -48,-124,-105, -82,-124, 204,-122, -97, -62, -92, -45, -1, -80, -80,-115,-110, -97; /M: SY='T'; M= -68, -89, -80, -86,-102, -99,-100, -85, -80, -94, -87, -59, -84, -87, -97, 29, 209, -69,-141, -97; /M: SY='R'; M= -7, -55, -44, -1, 21, -37, 19, -43, 12, -36, -43, -32, -52, -20, 54, 13, 41, -19, 10, 7; /M: SY='V'; M= -6, -30, -53, -42, -37, -43, -57, 0, -49, -1, -9, -32, -53, -51, -49, -14, 62, 63, -67, -45; /M: SY='L'; M= -7, -34, -66, -59, -21, -65, -54, 47, -59, 64, 45, -61, -62, -53, -58, -47, -41, -7, -55, -38; /M: SY='T'; M= 24, -21, -52, -27, -43, -50, -56, 19, -48, -2, -13, -39, -52, -48, -45, -6, 58, 47, -65, -46; /M: SY='H'; M= 19, -20, -7, 29, -32, 0, 73, -44, -21, -34, -25, -9, -50, 23, 4, 4, -11, -36, -23, 15; /M: SY='R'; M= -14, -61, -47, -36, -46, -50, -33, -24, 38, -2, -41, -40, -56, -27, 90, -38, -30, -41, -33, -45; /M: SY='I'; M= 22, -28, -63, -59, -6, -60, -57, 62, -56, 6, -6, -56, -58, -54, -58, -46, -18, 45, -53, 22; /M: SY='A'; M= 58, -38, -45, -25, -37, -18, -25, 7, -18, 15, -21, -37, -39, -12, -21, -20, -25, 21, -59, -31; /M: SY='W'; M= -17, -40, -12, -24, -13, -41, 52, -30, -9, -44, -15, -7, -57, -15, 51, -15, -35, -33, 75, 70; /M: SY='L'; M= -21, -54, -53, -39, -21, -52, -4, 10, -22, 70, 22, -51, -62, -23, -4, -41, -40, -20, -54, -19; /M: SY='I'; M= -11, -24, -65, -46, -20, -59, -46, 56, -47, 49, 15, -58, -61, -42, -51, -46, -40, 32, -57, -34; /M: SY='A'; M= 26, -44, 1, 19, -32, -31, -1, -11, -1, 20, -31, 0, -52, 25, 3, -4, 3, -20, -59, -22; /I: I=-6; MD=-30; /M: SY='E'; M= -4, -33, 6, 37, -54, -10, 17, -42, -2, -50, -13, 31, -45, 32, 21, 12, 9, -15, -64, -35; D=-6; /I: I=-6; MD=-30; /M: SY='G'; M= -25, -1, -9, 2, -51, 46, 29, -45, 6, -21, -24, -7, -21, -1, 12, -32, -40, -32, -21, 0; D=-6; /I: I=-6; MI=0; MD=-30; IM=0; DM=-30; /M: SY='G'; M= -28, -9, -1, -1, -41, 34, 3, -42, -2, -19, -49, 9, 3, 16, -3, -30, -40, -26, -53, -31; D=-6; /I: I=-6; DM=-30; /M: SY='V'; M= 11, -34, -26, -25, -25, -36, -2, 27, -28, 4, -24, -23, -13, -31, -36, -22, 2, 45, -19, 8; D=-6; /I: I=-6; DM=-30; /M: SY='P'; M= 4, -48, 40, 7, -52, -28, 9, -49, 3, -28, -38, 8, 45, 5, 6, 21, -1, -35, -42, -42; D=-6; /I: I=-6; DM=-30; /M: SY='P'; M= -3, -42, -27, -22, -41, -20, -5, -2, -22, -26, -37, -22, 95, -22, -22, -25, -22, -8, -39, -34; /M: SY='E'; M= -9, -59, 31, 46, -39, -2, 1, -56, 12, -43, -50, -2, -16, 26, 19, 21, -31, -45, 11, -14; /M: SY='Q'; M= -21, -32, 7, 31, -55, -21, 10, -55, 17, -57, -33, 28, -30, 51, 46, 14, -27, -38, -62, -40; /M: SY='I'; M= -43, -20, -67, -62, -25, -70, -63, 81, -36, 20, 14, -59, -59, -45, -60, -54, -25, 36, -58, -40; /M: SY='L'; M= -10, -18, -65, -58, -3, -41, -43, 16, -57, 69, 15, -61, -50, -49, -37, -54, -32, 9, -30, -24; /M: SY='A'; M= 47, 36, -59, -54, -10, -12, -56, 16, -53, 17, 17, -52, -57, -51, -47, -35, -27, 39, -59, -32; /M: SY='V'; M= -34, -25, -63, -58, -15, -65, -59, 39, -57, 44, 1, -48, -60, -55, -58, -25, 13, 55, -61, -40; /M: SY='T'; M= -6, -29, -42, -44, -43, -37, -49, -41, -41, -34, -3, -31, -44, -44, -49, 16, 98, -27, -68, -32; /M: SY='F'; M= -43, -55, -66, -63, 107, -35, -19, -34, -58, -23, -34, -49, -39, -50, -56, -33, -49, -31, -25, 40; /M: SY='T'; M= -29, -25, -39, -43, -52, -20, -47, -45, -25, -46, -17, 14, -27, -36, -41, 27, 94, -38, -69, -49; /M: SY='N'; M= -30, -41, -9, 11, -49, -41, -19, -55, 29, -59, -49, 76, -53, -20, 60, -23, -14, -32, -66, -50; /M: SY='K'; M= 39, -54, 1, -19, -53, -39, -24, -44, 63, -28, -30, 1, -38, -11, 21, 1, -20, -41, -59, -34; /M: SY='A'; M= 84, -38, -51, -44, -55, -17, -51, -32, -46, -14, -30, -37, -40, -36, -43, 0, -18, -35, -59, -52; /M: SY='A'; M= 79, -20, -44, -43, -37, -29, -51, -41, -27, -48, -31, -43, -40, -32, -12, -2, 12, -4, -59, -36; /M: SY='A'; M= 30, -50, 9, 22, -54, -2, -2, -36, 14, -37, -12, 21, -50, 26, 26, 8, -17, -28, -62, -47; /M: SY='E'; M= -16, -40, 21, 90, -55, -41, -23, -56, -22, -48, -53, 15, -42, -5, -25, -19, -22, -45, -64, -44; /M: SY='M'; M= -28, -53, -55, -58, 8, -63, -45, 27, -53, 44, 102, -57, -59, -48, -33, -54, -39, -8, -53, -10; /M: SY='R'; M= -5, -59, -30, -10, -33, -42, -16, -21, 54, -35, -44, -30, -52, 16, 68, -4, -13, -30, -57, -30; /M: SY='E'; M= 11, -57, 22, 56, -46, -6, 8, -42, -1, -38, -25, 2, -47, 17, 5, 15, -3, -44, -52, -29; /M: SY='R'; M= -28, -46, -27, -24, -58, -45, -36, -54, 17, -41, -33, -19, -56, -14, 100, -22, -41, -56, -59, -46; /M: SY='I'; M= -17, -54, -65, -50, -2, -66, -59, 57, -58, 42, -2, -49, -60, -44, -59, -39, -24, 45, -57, -24; /M: SY='R'; M= 7, -33, -12, 18, -18, 2, -4, -22, 1, -9, -14, 4, -52, 18, 40, 5, 1, -17, -58, -9; /M: SY='Q'; M= 23, -31, 15, 24, -53, -27, -12, -44, 30, -19, -18, 1, -23, 32, 10, 13, 1, -32, -51, -44; /M: SY='R'; M= 1, -49, -46, -26, -12, -44, -14, 5, 2, 34, 13, -14, -57, -2, 46, -15, -9, -9, -13, -4; /M: SY='L'; M= -16, 17, -30, -44, 6, -14, -46, 28, -41, 55, -2, -41, -37, -43, -41, -29, -18, 14, -56, -29; /M: SY='G'; M= 3, -36, -5, -1, -53, 41, 3, -18, 2, -32, -35, 1, 24, 10, 4, 2, -7, -8, -17, -36; /M: SY='E'; M= -9, -58, 22, 32, -31, 5, -8, -32, 18, -21, -19, 13, 12, 23, 10, 3, -15, -25, -61, -29; /I: I=-3; MD=-13; /M: SY='W'; M= 28, -32, 7, 12, -34, -10, -5, -28, -2, 0, -22, -2, -15, -14, -3, 7, 6, -17, 43, -30; D=-3; /I: I=-3; MD=-13; /M: SY='A'; M= 24, -25, -17, -16, -25, 9, -11, -17, -7, 6, -12, -13, -22, -7, -3, 1, -3, -3, -39, -14; D=-3; /I: I=-3; MD=-13; /M: SY='A'; M= 14, -25, -17, 4, -37, 1, -16, -6, -8, -16, 0, -18, -25, 3, 11, 1, -9, -15, -65, -20; D=-3; /I: I=-3; MD=-13; /M: SY='K'; M= -1, -43, -10, -16, -42, -17, -27, -42, 0, -17, -32, -8, -17, -9, -4, -7, -35, -45, -76, -27; D=-3; /I: I=-3; MD=-13; /M: SY='D'; M= -28, -40, -4, -27, -12, -39, -49, -38, -57, -25, -60, -26, -14, -18, -27, -24, -26, -57, -56, -59; D=-3; /I: I=-3; MI=0; MD=-13; IM=0; DM=-13; /M: SY='R'; M= -10, -50, 13, 28, -36, 28, -30, -35, 6, -21, -32, 5, -12, 12, 38, -9, -3, -43, -60, -28; D=-3; /I: I=-3; DM=-13; /M: SY='P'; M= 19, -45, -59, -44, -9, -49, -30, 24, -51, 28, 40, -46, 42, -45, -49, -28, -19, 33, -58, -28; /M: SY='W'; M= -1, -51, 4, 10, 4, -39, 4, -25, 3, -6, -5, 3, -17, 14, -3, -7, 22, -19, 81, 0; /M: SY='I'; M= 4, -18, -63, -59, -8, -46, -62, 67, -56, -6, -2, -44, -58, -33, -59, -16, -21, 54, -60, -41; /M: SY='G'; M= -11, 3, -12, -26, 0, 44, -12, -38, -9, -39, -14, -22, -52, 25, 24, 35, 0, -33, -42, -13; /M: SY='T'; M= -35, -45, -40, -44, -50, -40, -37, -42, -37, -39, -32, -2, -43, -44, -48, -15, 105, -32, -71, -48; /M: SY='F'; M= -43, -37, -67, -63, 86, -58, -53, 47, -59, 11, 1, -53, -38, -62, -59, -45, -32, -2, -2, 18; /M: SY='H'; M= -42, -63, 30, -25, -52, -52, 133, -68, -40, -50, -40, -10, -52, -19, -30, -37, -42, -67, -83, -13; /M: SY='S'; M= 38, -50, -29, -25, -59, 33, -30, -57, -21, -54, -51, -21, -41, -15, -25, 69, -20, -48, -61, -37; /M: SY='F'; M= -16, -55, -65, -54, 78, -54, -31, 11, -58, 35, 5, -56, -64, -55, -56, -49, -29, -9, 49, 35; /M: SY='C'; M= 45, 109, -56, -50, -7, 20, -56, -46, -45, -37, -39, -45, -59, -53, -57, -12, -23, -21, -46, -33; /M: SY='Q'; M= 2, -55, -41, -16, 16, -25, 24, -27, -21, 32, -4, 6, -57, 32, -2, -1, -18, -9, -5, 25; /M: SY='R'; M= -10, -60, 18, 6, -31, -25, 2, -55, 28, -37, -29, -1, -52, 23, 64, 0, -12, -51, -5, 0; /M: SY='I'; M= -29, -26, -63, -57, 13, -65, -35, 54, -55, 38, 34, -33, -60, 10, -55, -49, -27, 25, 20, -4; /M: SY='L'; M= -21, -26, -66, -59, -16, -67, -54, 28, -59, 70, -11, -63, -64, -54, -58, -51, -30, 19, -23, -18; /M: SY='R'; M= -16, -25, -13, -18, -45, -13, 7, -41, 26, -28, -41, -3, -40, 26, 75, -4, -11, -32, -60, -40; /M: SY='R'; M= -8, -36, 4, 36, -30, -37, -9, -33, 22, -22, -12, -17, -37, 41, 46, 4, -10, -43, -57, -7; /M: SY='H'; M= -2, -45, 2, 12, 32, -27, 74, -32, -30, -15, -16, 7, 5, -19, -29, -24, -24, -17, -32, 49; /M: SY='W'; M= 25, -17, -30, -9, 8, 33, 18, 3, -22, -36, -35, -19, 31, -30, -23, -13, -32, -26, 42, 22; /M: SY='Y'; M= -5, -29, 12, 11, 16, -15, 8, -14, 12, -1, -31, -5, 16, 9, 3, -13, -11, -18, -19, 25; /M: SY='E'; M= 2, -38, 6, 34, -22, -29, 21, -21, 6, 7, -9, 1, -12, 1, 26, -14, -14, -13, -5, -16; /I: I=-5; MD=-23; /M: SY='L'; M= 13, -39, -48, -37, -9, -10, -21, 20, -50, 21, -25, -35, -53, -39, -26, -2, -24, 5, -23, -7; D=-5; /I: I=-5; MI=0; MD=-23; IM=0; DM=-23; /M: SY='G'; M= -18, -50, 24, -18, -70, 45, -25, -33, -23, -36, -53, 10, 6, -31, -16, -26, -45, -42, -57, -60; D=-5; /I: I=-5; DM=-23; /M: SY='Y'; M= -22, -29, -42, -38, 13, -13, -18, 13, -43, 25, -19, -9, -26, -30, -16, -19, -25, -2, 11, 28; D=-5; /I: I=-5; DM=-23; /M: SY='P'; M= -5, -55, 29, 17, -43, -6, -26, -39, 8, -42, -42, 10, 36, -12, -17, 5, -14, -28, -28, -52; D=-5; /I: I=-5; DM=-23; /M: SY='P'; M= 3, -48, -12, 2, -18, -20, -13, -33, 2, -47, -33, -9, 53, 3, 15, 19, -12, -44, -64, -27; D=-5; /I: I=-5; DM=-23; /M: SY='N'; M= -22, -43, 27, 2, -55, 18, 11, -51, -9, -33, -38, 39, 9, 17, 3, 2, -14, -42, -68, -27; D=-5; /I: I=-5; DM=-23; /M: SY='F'; M= -16, -60, -50, -26, 78, -43, -34, -24, -30, -1, 1, -33, 21, -37, -34, -35, -11, -17, 36, 6; D=-5; /I: I=-5; DM=-23; /M: SY='R'; M= -13, -43, -9, 11, -39, -20, -14, -20, -2, -21, -37, -2, -40, 20, 47, 22, 32, -11, -40, -23; /M: SY='I'; M= -13, -56, -42, -30, -22, -55, -49, 58, -40, 35, 13, -55, -5, -26, -21, -35, -15, 28, -57, -22; /M: SY='L'; M= -4, -21, 0, -22, 7, -40, -43, 30, -10, 35, 25, -33, -23, -29, -26, -33, -11, 5, -35, 24; /M: SY='D'; M= -26, -58, 74, 23, -52, -15, -24, -27, -27, -22, -31, -6, -12, 11, -22, 13, 18, -40, -26, -33; /M: SY='D'; M= -4, -37, 41, 39, -45, 1, -31, -34, -24, -32, -20, -1, 19, 9, -3, 28, -3, -34, -65, -44; /I: I=-9; MD=-47; /M: SY='D'; M= 17, -58, 30, 19, -48, -14, 5, -34, 9, -23, -37, 8, -14, 16, 4, 0, 13, -32, 15, -31; D=-9; /I: I=-9; MI=0; MD=-47; IM=0; DM=-47; /M: SY='D'; M= -3, -52, 68, 41, -42, -29, -6, -24, -17, -31, -35, -11, -32, 8, 3, -10, -21, -41, -38, -36; D=-9; /I: I=-9; DM=-47; /M: SY='Q'; M= 9, -13, -5, 1, -48, -20, -13, -18, 7, -13, -18, -13, -24, 68, 18, 4, 5, -24, -14, -17; /M: SY='R'; M= 0, -57, 20, 15, 6, -27, -4, -8, 6, 10, -5, -17, -42, 17, 20, -11, 2, -20, 16, 1; /M: SY='R'; M= 22, -56, -1, -5, -17, -14, -3, -17, 1, 0, -10, -1, -18, 26, 32, 0, -8, -8, -6, -24; /M: SY='L'; M= -16, -41, -49, -22, 15, -56, -11, 41, -45, 48, 20, -45, -60, -30, -25, -30, -16, 14, -21, 0; /M: SY='I'; M= -2, -9, -31, -11, -9, -41, -34, 42, -18, 37, 21, -39, -32, -18, -16, -29, -23, 13, -3, -12; /M: SY='K'; M= 12, -46, 9, 7, -35, -17, 5, -39, 50, -36, -19, -2, -48, 23, 32, 0, -24, -22, -21, -21; /M: SY='E'; M= -13, -50, 34, 44, -38, -27, 7, -36, 0, -28, -22, -4, -26, 33, 37, 3, -7, -35, -29, -41; /M: SY='W'; M= 18, 0, -14, -20, -3, -46, -20, 35, -50, 22, 1, -32, -58, -21, -25, -29, -21, 30, 49, 1; /M: SY='L'; M= -4, 3, 2, -18, 3, -28, -40, 18, -27, 33, 17, -37, -41, -18, 6, -20, -10, 13, 11, 8; /I: I=-1; MD=-5; /M: SY='R'; M= 5, -40, 5, 17, -20, -28, 3, -47, 29, -29, -19, -5, -27, 11, 35, 5, -11, -40, 14, -8; D=-1; /I: I=-1; MD=-5; /M: SY='E'; M= -10, -64, 28, 38, -41, 0, -13, -47, 10, -36, -40, -3, -26, 19, 8, -11, -17, -45, 28, 10; D=-1; /I: I=-1; MD=-5; /M: SY='W'; M= -23, -3, 3, -24, -6, -30, 18, -13, -21, 27, 12, -30, -37, -7, -13, -25, -27, -3, 31, 20; D=-1; /I: I=-1; MD=-5; /M: SY='W'; M= -5, -27, -18, -7, -2, 0, -35, -30, -12, 1, -31, 16, -2, -28, 8, -3, -27, -23, 28, -31; D=-1; /I: I=-1; MD=-5; /M: SY='E'; M= -22, -59, -11, 12, -28, -28, -8, -47, -22, -12, -37, -7, -36, -10, 1, -20, -36, -28, -6, -20; D=-1; /I: I=-1; MD=-5; /M: SY='D'; M= -19, -68, 6, 1, -53, -41, -22, -40, -24, -53, -60, -32, -13, -13, -5, -16, -24, -35, -62, -23; D=-1; /I: I=-1; MD=-5; /M: SY='H'; M= -23, -65, -36, -3, -29, -20, 9, -42, -43, -24, -43, -29, -23, -39, -37, -35, -39, -31, -39, -18; D=-1; /I: I=-1; MI=0; MD=-5; IM=0; DM=-5; /M: SY='R'; M= -18, -70, -6, -24, -37, -23, -22, -48, -12, -38, -68, -23, -16, -5, 1, -31, -42, -36, -45, -42; D=-1; /I: I=-1; DM=-5; /M: SY='P'; M= -16, -35, -10, -9, -26, -37, -39, -39, -17, -27, -56, -20, 5, -30, -21, -6, -21, -23, -33, -24; D=-1; /I: I=-1; DM=-5; /M: SY='L'; M= 4, -26, -14, 15, 7, -4, -21, 11, -17, 21, -18, -23, -20, -14, -14, -4, -5, -2, 3, -11; D=-1; /I: I=-1; DM=-5; /M: SY='W'; M= -8, -50, 38, 3, -14, -16, -5, -16, 9, 7, -19, 10, -5, 6, 0, -6, -9, -24, 46, -7; /M: SY='E'; M= 8, -35, 21, 28, -16, -11, -25, -12, -9, -11, -28, 8, 13, -5, -7, 1, 21, -23, 6, -15; /M: SY='D'; M= -7, -30, 33, 12, -33, -17, -3, -36, 32, -13, -24, 14, -11, 4, 3, 1, 8, -29, 14, 3; /M: SY='R'; M= 1, -23, 13, 16, -19, -13, -21, -24, 30, -26, -22, -5, -1, 10, 31, -6, 9, -8, -47, -29; /M: SY='W'; M= -7, -47, 25, 22, 11, -8, -38, -10, 12, -9, -6, -25, 2, 6, -22, -15, -6, -7, 43, 22; /M: SY='P'; M= -1, -57, 11, 15, 13, -32, 7, -19, 5, 13, -1, -14, 19, 12, 4, -3, -6, -18, -6, -17; /M: SY='P'; M= 1, -10, -5, -2, -13, -33, -28, 5, -12, 14, -18, -12, 42, 0, 5, -24, -14, 12, -9, 1; /I: I=-15; MD=-77; /M: SY='R'; M= 3, -28, 17, 12, -16, -22, -2, -31, 31, -30, -41, 0, -10, 19, 39, -4, -5, -27, -38, -23; D=-15; /I: I=-15; MI=-77; IM=-77; DM=-77; /M: SY='Q'; M= 0, -52, 15, 21, -5, -21, -20, -18, 11, 4, -3, 0, -36, 31, -5, -4, 12, -13, 10, -12; /M: SY='L'; M= 14, -38, -12, -16, 10, -33, -16, 28, -23, 30, 13, -24, -40, -24, -13, -26, -19, 22, 6, -18; /M: SY='Q'; M= 6, -8, -16, -7, -4, -27, 5, 2, 6, 17, 8, -11, -33, 29, 28, -16, -17, -10, -17, -6; /M: SY='W'; M= 8, -52, 10, 10, -17, -1, -4, -28, 8, -18, -33, 16, -18, 12, 6, 26, 3, -28, 33, -7; /M: SY='F'; M= 7, -30, -21, 15, 18, -23, -8, 4, 1, 5, 2, -17, -28, 18, 9, -14, -3, -4, 8, 13; /M: SY='I'; M= -5, -29, -20, -15, 10, -38, -34, 61, -12, 15, 5, -34, -28, -25, -24, -23, -21, 9, -10, -10; /M: SY='S'; M= -1, -34, 21, 14, -19, -11, -22, -24, 4, -7, -8, 10, -21, 1, -3, 48, -15, -28, -45, -24; /M: SY='W'; M= -5, -32, 13, 10, -9, -12, -21, -30, 17, -13, -8, 17, -28, 2, 31, -2, -13, -22, 51, 13; /M: SY='W'; M= 31, 15, -18, -27, -5, -39, -33, -5, -5, 12, -7, -27, -17, 22, -11, -11, -21, -1, 78, -8; /M: SY='K'; M= -2, -9, -20, 5, -32, -23, -29, -23, 63, -16, -20, 0, -33, -2, 19, -12, -14, -14, -12, -3; /M: SY='N'; M= 15, -48, 26, 25, -24, -10, -22, -25, -6, -38, -32, 50, -29, 1, -4, 18, -7, -23, -15, -18; /M: SY='E'; M= -14, -12, 23, 25, -25, -15, 1, -25, 15, -4, -10, 2, -16, 25, 11, 17, -21, -25, -36, -1; /M: SY='M'; M= 4, -8, -21, -22, 5, 30, -27, -16, -18, 30, 34, -4, -31, -16, -7, -25, -18, -14, 5, -8; /M: SY='L'; M= -13, -7, -1, -8, -6, -37, -22, 19, -4, 26, -6, -7, -32, -16, 17, -13, -8, 21, -18, -14; /M: SY='P'; M= -6, -20, 15, -8, -34, -4, -25, -23, -1, -6, 6, 9, 29, -14, 14, 18, 28, -24, -62, -29; /M: SY='P'; M= -4, -27, -5, 2, -23, -25, 15, -24, -13, -22, -19, -1, 78, -4, 13, -11, -17, -26, -33, -14; /M: SY='E'; M= 10, -23, 31, 36, -32, 2, 8, -35, -2, -9, -33, 12, -17, 9, 0, 0, -16, -22, -42, -16; /M: SY='D'; M= -6, -44, 37, 30, -20, -2, 9, -26, 0, -15, -9, -5, 9, 21, -3, -13, -8, -17, -4, -3; /M: SY='Y'; M= 16, -36, 3, 15, 0, -23, -23, 6, -14, 12, -13, -31, -15, -17, -23, -3, -8, 10, -43, 36; /M: SY='Q'; M= 8, -57, 15, 11, -7, -29, -13, -2, -3, 7, -20, -9, 14, 30, -6, -9, -13, 2, 16, -11; /M: SY='E'; M= 13, -27, 15, 18, -14, -7, -21, -14, 8, 2, -17, -10, 9, 7, 17, 0, -6, -26, -20, -21; /M: SY='E'; M= 5, -16, 14, 20, -12, -5, 15, -9, 0, 3, -18, 0, -30, -5, 14, 11, -12, -19, -9, -10; /M: SY='A'; M= 22, -21, 4, 5, -21, -6, -10, -16, 0, 9, -3, -9, -9, 21, 3, 1, -5, -6, -37, -19; /M: SY='D'; M= 8, -30, 20, 0, -21, -14, -3, 2, -6, -3, -15, 12, -10, 11, 15, 3, 4, -15, -12, -11; /I: I=-1; MD=-6; /M: SY='N'; M= 18, -49, 12, 15, -19, -7, -6, -17, -5, -16, -23, 19, -4, 7, 9, 1, 3, -13, -14, 0; D=-1; /I: I=-1; MD=-6; /M: SY='Q'; M= 5, -18, 9, 9, -5, -7, 11, -10, -4, -11, -23, 2, 7, 14, 7, 5, -7, -15, -4, 10; D=-1; /I: I=-1; MD=-6; /M: SY='R'; M= 6, -44, 0, 11, -3, 1, 5, -13, 0, 9, -31, -8, -2, 7, 26, -16, -25, -27, -19, 0; D=-1; /I: I=-1; MD=-6; /M: SY='R'; M= -11, -10, 10, 17, -25, -23, -31, -19, -12, -3, -25, -23, -8, 4, 23, -16, -30, -14, -33, -24; D=-1; /I: I=-1; MD=-6; /M: SY='E'; M= -30, -44, 8, 30, -46, -40, -2, -54, -2, -45, -30, -14, 1, 13, 14, -21, -22, -42, -12, -28; D=-1; /I: I=-1; MD=-6; /M: SY='E'; M= -30, -66, -6, 1, -2, -33, -11, -30, -32, -12, -18, -15, -10, -31, -16, -28, -28, -30, -4, -21; D=-1; /I: I=-1; MD=-6; /M: SY='W'; M= 3, -44, -35, -25, -39, -47, -12, -11, -30, -35, -35, -42, -4, -24, -34, -44, -40, -21, 34, -44; D=-1; /I: I=-1; MI=0; MD=-6; IM=0; DM=-6; /M: SY='H'; M= -14, -58, -12, 7, -56, -44, 8, -42, -17, -52, -54, -28, -38, 4, 6, -39, -30, -37, -36, -30; D=-1; /I: I=-1; DM=-6; /M: SY='A'; M= 16, -59, -22, -15, -9, -54, -64, -3, -18, 6, -11, -47, -52, -22, -34, -33, -5, -24, -11, -40; D=-1; /I: I=-1; DM=-6; /M: SY='L'; M= 17, -20, -50, -49, 9, -29, -62, 13, -44, 22, 5, -46, -53, -40, -36, -43, -19, 15, -9, -17; D=-1; /I: I=-1; DM=-6; /M: SY='W'; M= 31, -22, -20, -13, -19, -16, -10, -10, -8, 0, -34, -20, -38, -4, -7, -19, -27, -9, 46, -20; D=-1; /I: I=-1; DM=-6; /M: SY='P'; M= 1, -64, 19, 21, -42, -16, 13, -37, 2, -31, -43, -12, 22, 9, 18, -15, -2, -40, 21, -2; D=-1; /I: I=-1; DM=-6; /M: SY='V'; M= -1, 26, -48, -24, 33, -38, -39, 30, -47, 33, -6, -39, -49, -49, -27, -36, -24, 36, -22, -3; /M: SY='Y'; M= 0, -25, -42, -32, 26, -37, -6, 4, -30, 15, -10, -29, -55, -30, -9, -19, -36, 0, 10, 83; /M: SY='E'; M= 18, -47, 2, 44, -46, -25, -9, -38, 19, -30, -33, -9, -18, 29, 24, -5, -7, -16, -14, -13; /M: SY='R'; M= 28, -17, 0, 31, -32, -16, 3, -16, -2, -3, -15, -18, -51, 15, 31, -1, -13, -29, -28, -26; /M: SY='Y'; M= -31, -60, -49, -36, 41, -53, -21, -27, -42, 7, -18, -50, -64, -38, -37, -46, -37, -8, 34, 105; /M: SY='Q'; M= 4, -20, 8, 47, -51, -37, 5, -27, 5, -15, -20, -9, -30, 59, 17, -23, -15, -28, -9, -31; /M: SY='Q'; M= 20, -32, 20, 35, -47, -32, -10, -39, 23, -33, -26, 19, -32, 37, 20, -10, -7, -33, -61, -30; /M: SY='R'; M= 8, -39, -27, 19, -5, -35, 15, -11, -1, 3, 14, -18, -29, 15, 34, -18, -9, -2, -11, 19; /M: SY='K'; M= -40, 13, -39, -30, -18, -40, -32, -22, 53, 50, 10, -26, -57, -15, 11, -33, -28, -27, -19, -33; /M: SY='R'; M= 8, -41, 15, 7, -43, -15, -11, -23, 35, -17, -37, -6, -37, 27, 50, -12, -22, -33, -28, -30; /M: SY='E'; M= 11, -47, 14, 37, -33, -30, -15, -39, 23, -16, -17, 0, -43, 29, 30, 7, 0, -37, -61, -46; /M: SY='R'; M= 8, -31, -2, 14, -30, -29, 26, -43, 12, -10, -25, 26, -47, 26, 42, -3, -21, -37, -8, 12; /M: SY='N'; M= -7, -23, -7, -10, -41, 48, 6, -54, 4, -47, -24, 65, -23, 4, 2, -1, -37, -56, -30, -40; /M: SY='A'; M= 30, 1, -46, -8, -9, -34, -16, 2, -9, 26, -11, -35, -41, 3, -11, -9, -24, 12, 29, 11; /M: SY='L'; M= -20, -19, -49, -46, 2, -64, -34, 37, -40, 43, 36, -51, -51, -24, -13, -37, -25, 33, -2, 5; /M: SY='D'; M= -33, -44, 95, 3, -38, -7, -16, -42, -34, -44, -43, -15, -39, -29, -46, 8, 12, -56, -76, -51; /M: SY='F'; M= -32, -41, -43, -56, 97, -58, -17, -19, -46, -12, -6, -56, -15, -46, -38, -42, -34, -26, -12, 57; /M: SY='D'; M= 8, -57, 76, 18, -55, 3, -24, -51, -37, -56, -56, 29, -15, -10, -30, 21, -18, -53, -70, -31; /M: SY='D'; M= -23, -61, 96, 21, -56, -19, -23, -54, -38, -26, -14, -11, -37, -17, -33, -16, -24, -54, -74, -28; /M: SY='L'; M= -15, -34, -33, -38, -22, -49, -49, 19, -41, 60, 55, -56, -39, 10, -49, -31, -43, 4, -24, -26; /M: SY='I'; M= -13, -44, -44, 5, -13, -38, -52, 48, -46, 46, 12, -37, -28, 4, -32, -30, -39, 6, -29, -26; /M: SY='H'; M= -6, -45, -23, -15, -9, -29, 37, 6, -25, 27, 11, -15, -37, -2, 12, -1, 8, -3, 19, 18; /M: SY='R'; M= -5, -38, -6, 10, 5, -38, 5, -3, 10, 28, -15, -5, -55, 4, 29, -21, -17, -27, 5, 14; /M: SY='A'; M= 50, 40, -42, -31, -24, -37, -52, -36, -40, 10, -14, -36, 24, -46, -35, -5, 36, -8, -4, -33; /M: SY='V'; M= 10, -5, -8, -25, -15, -50, 7, 8, -20, 24, -26, -11, -37, -32, -3, -22, -5, 33, -10, 33; /M: SY='R'; M= 7, -38, 13, 32, -32, -34, 2, -27, 9, -5, -14, 4, -15, 28, 34, -7, -9, -25, -19, -29; /M: SY='L'; M= 20, -27, -49, -30, -19, -36, -31, 19, -41, 56, 19, -40, -51, -30, -21, -42, -23, 3, -36, -8; /I: I=-6; MD=-28; /M: SY='L'; M= -15, -38, -58, -50, 33, -50, -31, 10, -33, 63, 21, -49, -47, -24, -28, -42, -43, -5, -8, -29; D=-6; /I: I=-6; MI=0; MD=-28; IM=0; DM=-28; /M: SY='E'; M= -9, -37, -3, 22, -63, -28, -34, -43, -2, -24, -45, -15, -27, 11, 22, -10, -15, -26, -44, -39; D=-6; /I: I=-6; DM=-28; /M: SY='Q'; M= -6, -45, 7, 25, -54, -20, -5, -48, -2, -43, -25, 19, -54, 29, 7, -8, -4, -18, -72, -46; D=-6; /I: I=-6; DM=-28; /M: SY='N'; M= -20, -33, 31, -18, -6, -12, 30, -47, -30, -48, -50, 49, -1, -5, -5, -6, -29, -39, -69, -2; D=-6; /I: I=-6; DM=-28; /M: SY='P'; M= -1, -52, -3, 20, -59, -26, -11, -32, -19, -62, -47, -21, 73, -4, -10, 0, -10, -44, -69, -61; D=-6; /I: I=-6; DM=-28; /M: SY='W'; M= 2, -27, 33, 41, -38, -26, 5, -34, -8, -26, -37, -3, 3, 13, -1, -15, -27, -40, 51, -45; D=-6; /I: I=-6; DM=-28; /M: SY='V'; M= -8, -42, -34, -18, -4, -48, -49, 36, -25, 28, -13, -21, -46, -33, -32, -21, -16, 48, -18, -14; D=-6; /I: I=-6; DM=-28; /M: SY='R'; M= 24, -14, -28, -23, -18, -11, -4, -16, 0, 29, -29, -27, -52, 9, 43, -20, -25, -15, -57, -20; D=-6; /I: I=-6; DM=-28; /M: SY='E'; M= 24, -44, 14, 26, -26, -8, 3, -28, 16, -27, -29, 11, -6, 19, 13, -5, -9, -32, -58, 0; /M: SY='K'; M= 13, -57, -5, 14, -7, -33, 25, -25, 32, -17, -11, -15, -36, 22, 31, -1, -4, -29, -21, -1; /M: SY='W'; M= -21, -2, -45, -4, 11, -43, -16, 16, -44, 28, -6, -45, -8, -8, -35, -47, -29, 10, 72, 58; /M: SY='Q'; M= -4, -45, 10, -14, -41, -19, 14, -34, -5, -29, -43, -18, -10, 61, 59, 0, -14, -26, -19, -25; /M: SY='Q'; M= 4, -48, 16, 21, -47, -7, -5, -45, 10, -25, -33, 30, -13, 37, 21, 20, -17, -35, -61, -14; /M: SY='R'; M= -34, -29, -27, -15, -31, -17, 7, -35, 27, -18, -37, 2, 5, 30, 71, -14, -18, -44, -3, -20; /M: SY='Y'; M= -31, -32, -63, -60, 72, -42, -20, 19, -55, 0, -12, -58, -37, -56, -52, -52, -30, -1, 62, 74; /M: SY='R'; M= -26, -34, 38, 4, -36, -33, 6, -60, 35, -51, -49, -15, 24, 28, 51, -5, 1, -52, -61, -23; /M: SY='H'; M= -4, -31, -35, 3, 9, -51, 91, -21, -42, -9, -30, -35, -57, -37, -37, -27, -30, 11, 2, 69; /M: SY='I'; M= -4, -45, -51, -50, -6, -65, -48, 61, -43, 24, 0, -59, -59, -55, -47, -51, -39, 55, -45, -40; /M: SY='L'; M= -43, -22, -65, -44, 27, -65, -27, 15, -57, 61, 57, -49, -47, -34, -56, -45, -37, 13, -34, -16; /M: SY='V'; M= -36, -3, -63, -22, -32, -53, -65, 50, -57, -4, -13, -59, -45, -45, -59, -44, -34, 77, -65, -43; /M: SY='D'; M= -90,-127, 222, -30,-107, -83, -73,-135, -64,-132,-130, -38, -79, -75, -66, -77, -81,-111,-168,-105; /M: SY='E'; M= -77,-127, 21, 202,-128,-116, -73,-130, -51,-105,-110, -58, -79, -37, -59, -66, -73,-100,-126, -67; /M: SY='Y'; M= 22, -24, -46, -56, 75, -40, -17, -22, -52, -25, -17, -43, -62, -52, -51, -21, -40, -22, -26, 83; /M: SY='Q'; M= -33, -67, -37, -5, -72, -50, -20, -58, -23, -54, -41, -33, -49, 121, -24, -23, -37, -60, -55, -44; /M: SY='D'; M= -50, -64, 109, -1, -68, -48, -11, -66, -37, -58, -63, -11, -50, -14, -37, -39, -40, -49, -83, -40; /M: SY='T'; M= -25, -2, -47, -48, -31, -53, -24, 19, -45, 4, -3, -10, -49, -34, -51, 5, 83, 2, -65, -26; /M: SY='N'; M= -33, -52, 50, -29, -59, -16, -10, -51, -31, -51, -53, 82, -51, -30, -35, 43, 10, -55, -74, -43; /M: SY='P'; M= -3, -48, -26, 16, -29, -31, 33, -22, -6, -11, -25, -19, 73, 3, 2, -13, -6, -21, -39, -10; /M: SY='L'; M= 24, -12, -26, -30, -31, -49, -33, 28, -31, 29, 1, -41, -28, 22, -27, -6, 0, 25, -45, -43; /M: SY='Q'; M= -10, -65, -30, -7, -68, -43, -1, -55, -21, -41, -15, -31, -31, 114, -5, -27, -38, -44, -41, -44; /M: SY='W'; M= -8, -60, -38, 13, 27, -45, 3, -16, -29, 9, 1, -31, -58, 1, -23, -29, -29, -28, 84, 75; /M: SY='R'; M= 9, -58, 13, 39, -44, -31, -10, -45, 12, -20, -25, -11, -33, 25, 48, -6, -5, -18, -29, -41; /M: SY='W'; M= -30, -36, -67, -52, 8, -58, -57, 55, -59, 54, 25, -62, -62, -44, -59, -56, -31, 5, 56, -33; /M: SY='L'; M= -24, -49, -45, -59, 22, -66, -56, 43, -42, 54, 7, -60, -62, -41, -57, -52, -25, 34, -54, -30; /M: SY='R'; M= -1, -41, 6, 25, -27, -39, -11, -49, 39, -34, -22, -5, -30, 24, 50, 4, -7, -40, -14, -27; /M: SY='L'; M= 22, -22, -40, -9, -19, -37, -11, -14, 2, 38, 10, -33, -45, -6, 17, 4, -8, -5, -19, -22; /M: SY='L'; M= -23, -54, -53, -59, 1, -54, -10, 40, -58, 64, 7, -61, -63, -53, -39, -46, -44, 4, 27, -24; /M: SY='A'; M= 47, 30, -46, -32, 24, -26, -22, -12, -31, -14, -24, -19, -43, -45, -27, 16, 17, 3, -17, 16; /M: SY='G'; M= 15, -45, -9, 12, -50, 37, -12, -46, 14, -26, -29, 3, 2, 15, 12, 11, -2, -37, -60, -30; /M: SY='E'; M= 0, -21, 24, 27, -53, 26, 3, -38, 16, -36, -36, 13, 20, -5, -3, 2, -6, -27, -63, -44; /M: SY='H'; M= -1, -28, 1, 1, 0, 25, 53, -52, 2, -45, -39, 23, -24, 0, 21, 7, 2, -40, -16, -12; /I: I=-3; MD=-14; /M: SY='N'; M= 0, -17, 16, 1, -9, 8, 17, -33, 2, -44, -40, 27, 12, 11, 6, 7, 6, -25, -63, -27; D=-3; /I: I=-3; MD=-14; /M: SY='N'; M= 0, -44, 9, -4, -38, -14, 0, -37, -7, -37, -27, 52, -4, 13, 3, 6, 6, -43, -67, -12; D=-3; /I: I=-3; MI=0; MD=-14; IM=0; DM=-14; /M: SY='L'; M= -25, -34, -65, -50, 11, -67, -56, 38, -58, 58, 9, -61, -63, -50, -45, -45, -14, 28, -56, -32; D=-3; /I: I=-3; DM=-14; /M: SY='F'; M= -40, 60, -59, -57, 73, -60, -51, -1, -53, -6, 31, -32, -59, -39, -55, -25, 43, 4, 4, 1; /M: SY='V'; M= 24, 26, -62, -48, -6, -50, -56, 27, -45, 12, 46, -55, -47, -51, -15, -42, -35, 54, -39, -30; /M: SY='V'; M= -1, -26, -64, -59, -22, -51, -65, 32, -57, -15, -15, -58, -60, -58, -59, -39, -18, 83, -66, -44; /M: SY='G'; M= -14, -59, -36, -44, -39, 95, -53, -71, -52, -67, -57, -33, -51, -49, -59, -27, -31, -64, -56, -59; /M: SY='D'; M= -38, -63, 111, -15, -70, -41, -37, -67, -28, -66, -65, -19, -50, -37, -46, -27, -32, -57, -85, -53; /M: SY='P'; M= -8, -63, 55, 3, -33, -31, -46, -28, -23, -50, -50, -17, 81, -42, -34, -12, -18, -1, -45, -20; /M: SY='D'; M= -23, -33, 74, -17, -45, -42, 24, -49, 48, -54, -12, 39, -50, -32, -9, -20, -33, -54, 24, -43; /M: SY='Q'; M= -37, -66, -30, -11, -71, -50, -31, -57, -23, -53, -27, -33, -49, 121, -19, -23, -28, -53, -55, -44; /M: SY='S'; M= 39, 17, -37, -25, -56, -20, -45, -47, -34, -44, -31, -24, -49, -23, 7, 72, 11, -31, -64, -50; /M: SY='I'; M= -38, -60, -68, -66, -32, -72, -47, 97, -61, -4, -19, -58, -57, -58, -64, -49, -30, 11, -57, -40; /I: I=-15; MI=0; MD=-77; IM=0; DM=-77; /M: SY='Y'; M= -47, -46, -45, -55, 24, -51, -16, -29, -41, -27, -6, -29, -47, -26, -46, -44, -41, -38, -14, 119; /M: SY='G'; M= 17, -55, -18, 3, -50, 47, -27, -61, -12, -51, -49, -21, -31, 6, 32, 42, -15, -54, -36, -51; /I: I=-15; MI=0; MD=-77; IM=0; DM=-77; /M: SY='W'; M= -47, -53, -67, -38, 93, -55, -24, -30, -54, -32, -40, -24, -43, -59, -29, -30, -35, -40, 118, 5; /M: SY='R'; M= -15, -62, -45, -30, -30, -43, -32, -51, -7, -38, -36, 2, -36, 18, 94, -21, -9, -44, -19, -37; /M: SY='G'; M= -25, -55, -17, -42, -37, 84, -21, -54, -43, -31, -35, -7, -27, 0, -38, -8, -29, -34, -58, -40; /M: SY='A'; M= 80, -30, -44, -44, -29, 4, -52, -46, -46, -38, -44, -35, -42, -43, -51, 15, -14, -15, -59, -52; /M: SY='D'; M= -14, -58, 68, 17, -29, -44, -7, -39, 3, -15, -34, 15, -50, -2, 11, 11, 4, -33, -14, -31; /M: SY='P'; M= -1, -59, -28, -32, -17, -11, -36, 28, -49, -9, -12, -42, 72, -37, -36, -8, -19, 28, -58, -9; /M: SY='E'; M= -3, -50, 25, 31, -13, -3, 13, -34, 1, -33, -8, 3, -25, 21, 22, 14, -2, -30, -37, -8; /M: SY='N'; M= -5, -5, -10, -26, 9, -17, -5, 1, -35, 9, -11, 62, -43, -33, -16, -3, 16, -10, -57, 15; /M: SY='F'; M= -25, -40, -62, -51, 60, -13, -26, 44, -45, 25, 24, -40, -61, -49, -44, -43, -16, -12, -40, 41; /M: SY='L'; M= -9, -54, 1, 2, 5, -17, -12, 10, -22, 39, 18, -9, -47, 2, -8, -8, -1, -7, -33, -34; /M: SY='N'; M= -2, -58, 27, 30, -50, -7, 8, -39, 11, -34, -27, 36, -50, 30, 36, -4, -17, -31, -64, -39; /I: I=-15; MI=0; MD=-77; IM=0; DM=-77; /M: SY='F'; M= 17, -54, -43, -25, 76, -49, -30, -4, 4, 13, 18, -30, -43, -30, -19, -40, -39, -18, 14, 0; /M: SY='R'; M= 4, -19, -3, 24, 16, -15, -7, -9, 11, -23, -40, -11, 9, 9, 35, -9, -23, -24, -41, 11; /M: SY='E'; M= -3, -12, 21, 30, -27, -5, 19, -40, 25, -34, -32, 10, -21, 27, 19, 7, -3, -39, -47, -33; /M: SY='D'; M= -4, -59, 58, 22, -37, -22, 9, -30, 4, -22, -14, -15, -24, 9, 35, -5, -9, -39, -63, -12; /M: SY='F'; M= -7, 13, -24, -31, 75, -39, 0, -11, -37, -15, -20, -33, -28, -22, -25, -16, -6, -13, 1, 53; /I: I=-5; MD=-27; /M: SY='P'; M= -2, -20, 4, 6, -6, 7, -7, -42, -3, -46, -49, 2, 66, 11, -10, 6, -18, -26, -61, -32; D=-5; /I: I=-5; MD=-27; /M: SY='D'; M= -3, -13, 26, -3, -52, 15, -2, -33, 0, -39, -43, 26, 8, 11, 8, -7, -12, -22, -47, -52; D=-5; /I: I=-5; MD=-27; /M: SY='A'; M= 25, -20, -6, -24, -47, -22, -18, -37, -23, 0, -31, -13, -11, -7, -9, -5, 11, -26, -55, -35; D=-5; /I: I=-5; MI=0; MD=-27; IM=0; DM=-27; /M: SY='K'; M= 0, -33, -4, 14, -46, -36, 18, -23, 38, -30, -31, 7, -15, 19, 34, 6, 19, -32, -61, -33; /M: SY='V'; M= -23, -16, -21, 2, -26, -48, 11, 15, 0, -3, -8, -26, -19, 8, 25, -6, 22, 33, -60, -7; /M: SY='I'; M= -26, -17, -33, -37, 21, -45, 11, 49, -26, 8, -12, -31, -42, -31, -13, -40, -16, 31, -32, 46; /M: SY='T'; M= -13, -55, -8, 8, -20, -48, 18, -18, 25, -13, -12, -4, -9, 0, 28, 8, 31, -2, -50, 2; /M: SY='L'; M= -43, -26, -65, -58, -10, -67, -51, 0, -58, 79, 22, -63, -51, -41, -40, -38, -22, -22, -54, -36; /M: SY='E'; M= -3, -37, 24, 47, -56, -13, -29, -32, -13, -32, -48, 23, -7, -4, -10, 18, 31, -23, -29, -22; /M: SY='Q'; M= -24, -27, -4, 30, -38, -30, 0, -17, 13, -38, -37, -16, -37, 52, 30, -21, 40, -9, -29, -14; /M: SY='N'; M= -14, 6, 4, -39, -58, -34, -30, -43, -34, -52, -51, 101, -40, -19, -35, 23, 6, -48, -75, -53; /M: SY='Y'; M= -38, -62, -57, -49, 61, -33, 15, -24, -48, -30, -35, -53, -58, -28, -7, -37, -46, -39, 64, 100; /M: SY='R'; M= -31, -65, -46, -28, -39, -53, -26, -57, -5, -53, -46, -40, -58, -24, 107, -44, -48, -58, -30, -44; /M: SY='S'; M= -23, 22, -33, -29, -1, -34, -34, -47, -26, -36, -43, 5, -49, -22, -42, 87, -4, -42, -6, -17; /M: SY='T'; M= 4, -16, -13, -31, -39, -1, -4, -33, -31, -33, -32, 8, -7, -8, 9, 34, 62, -15, -36, -41; /I: E1=0; IE=-255; DE=-255;» more |
Post-processing [info]
| PROMOTED_BY | PS51217 |
Numerical results [info]
| Total number of hits | 261 in 261 different sequences |
| Number of true positive hits | 261 in 261 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 9 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 96.67 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | N_Hulo |
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | UvrD-like helicase ATP-binding |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
261 sequences
ADDA_ACET2 (A3DH19), ADDA_ALKMQ (A6TVN2), ADDA_ALKOO (A8MJ41), ADDA_ANOFW (B7GM51), ADDA_BACAH (A0RAX7), ADDA_BACAN (Q81TW1), ADDA_BACC0 (B7JDU4), ADDA_BACC1 (Q73C23), ADDA_BACC2 (B7IL84), ADDA_BACC4 (B7HGP9), ADDA_BACC7 (B7HZR5), ADDA_BACCN (A7GM37), ADDA_BACCQ (B9ITE9), ADDA_BACCR (Q81GP9), ADDA_BACCZ (Q63EM2), ADDA_BACHK (Q6HM43), ADDA_BACLD (Q65LJ9), ADDA_BACMK (A9VJ02), ADDA_BACP2 (A8FBR1), ADDA_BACSU (P23478), ADDA_BACVZ (A7Z368), ADDA_CALS4 (Q8RCZ0), ADDA_CARHZ (Q3AA35), ADDA_CLOAB (Q97GV3), ADDA_CLOB1 (A7FPG0), ADDA_CLOB6 (C3L047), ADDA_CLOB8 (A6LPC4), ADDA_CLOBA (B2UX57), ADDA_CLOBB (B2THC8), ADDA_CLOBH (A5HYY0), ADDA_CLOBJ (C1FSA8), ADDA_CLOBK (B1IEN0), ADDA_CLOBL (A7GAJ8), ADDA_CLOBM (B1KUZ8), ADDA_CLOD6 (Q18AN9), ADDA_CLOK1 (B9DZK4), ADDA_CLOK5 (A5N628), ADDA_CLONN (A0PY67), ADDA_CLOP1 (Q0TV46), ADDA_CLOPE (Q8XPE2), ADDA_CLOPS (Q0SWW4), ADDA_DESAP (B1I493), ADDA_DESHD (B8FXD7), ADDA_DESHY (Q24WW8), ADDA_DESRM (A4J4E3), ADDA_ENTFA (Q836J8), ADDA_EXIS2 (B1YKM8), ADDA_GEOKA (Q5L263), ADDA_GEOTN (A4IKW7), ADDA_HELMI (B0TDI0), ADDA_LACAC (Q5FJX0), ADDA_LACCB (B3WEJ1), ADDA_LACDA (Q1GAA9), ADDA_LACDB (Q04AN7), ADDA_LACGA (Q043G6), ADDA_LACH4 (A8YVK0), ADDA_LACJO (Q74JA6), ADDA_LACLA (Q9CJI9), ADDA_LACLM (A2RH77), ADDA_LACLS (Q033I1), ADDA_LACP3 (Q038V7), ADDA_LACP7 (A9KTE6), ADDA_LACPL (Q88U41), ADDA_LATSS (Q38X69), ADDA_LEUCK (B1MZM2), ADDA_LEUMM (Q03W49), ADDA_LEVBA (Q03NA7), ADDA_LIGS1 (Q1WRS0), ADDA_LIMF3 (B2GEY4), ADDA_LIMRD (A5VHK2), ADDA_LIMRJ (B2G532), ADDA_LISIN (Q929A9), ADDA_LISMF (Q71X99), ADDA_LISMH (B8DF44), ADDA_LISMO (Q8Y511), ADDA_LISW6 (A0AL18), ADDA_LYSSC (B1HN90), ADDA_MOOTA (Q2RL77), ADDA_NATTJ (B2A610), ADDA_OCEIH (Q8ERW5), ADDA_OENOB (Q04GY7), ADDA_PEDPA (Q03D71), ADDA_PELTS (A5D1P3), ADDA_RUMCH (B8I2Y2), ADDA_STAA1 (A7X0I2), ADDA_STAA2 (A6U074), ADDA_STAA3 (Q2FIA8), ADDA_STAA8 (Q2FZT5), ADDA_STAA9 (A5IRE5), ADDA_STAAB (Q2YWW4), ADDA_STAAC (Q5HHB7), ADDA_STAAE (A6QFH8), ADDA_STAAM (Q99VC3), ADDA_STAAN (Q7A6H4), ADDA_STAAR (Q6GIC1), ADDA_STAAS (Q6GAV9), ADDA_STAAT (A8Z073), ADDA_STAAW (Q8NXE9), ADDA_STACT (B9DIS2), ADDA_STAEQ (Q5HQJ4), ADDA_STAES (Q8CPT9), ADDA_STAHJ (Q4L4Y3), ADDA_STAS1 (Q49WA6), ADDA_STRA1 (Q3K1I4), ADDA_STRA3 (Q8E5T9), ADDA_STRA5 (Q8E061), ADDA_STREM (B4U2H1), ADDA_STRGC (A8AY33), ADDA_STRMU (Q8DT76), ADDA_STRP1 (Q9A0H3), ADDA_STRP2 (Q04KF8), ADDA_STRP3 (P0CZ52), ADDA_STRP4 (B5E4P5), ADDA_STRP6 (Q5XCW6), ADDA_STRP8 (Q8P1J2), ADDA_STRPB (Q1JCJ8), ADDA_STRPC (Q1JMH5), ADDA_STRPD (Q1JHM1), ADDA_STRPF (Q1J7E4), ADDA_STRPG (A2RFA8), ADDA_STRPI (B1IBR6), ADDA_STRPJ (B8ZQ32), ADDA_STRPM (Q48UB8), ADDA_STRPN (Q97QP9), ADDA_STRPQ (P0CZ53), ADDA_STRPS (B2IPX3), ADDA_STRPZ (B5XKR4), ADDA_STRR6 (Q8DPR6), ADDA_STRS2 (A4W0M7), ADDA_STRS7 (C0MGY6), ADDA_STRSV (A3CNT9), ADDA_STRSY (A4VUD2), ADDA_STRT1 (Q5LY80), ADDA_STRT2 (Q5M2T7), ADDA_STRTD (Q03IZ8), ADDA_STRU0 (B9DRV0), ADDA_SYMTH (Q67MD5), ADDA_SYNWW (Q0AXU8), ADDA_THEP3 (B0KDB7), ADDA_THEPX (B0K213), ADDB_ACET2 (A3DH20), ADDB_ALKMQ (A6TVN9), ADDB_ALKOO (A8MJ51), ADDB_ANOFW (B7GM52), ADDB_BACAH (A0RAX6), ADDB_BACAN (Q81TW2), ADDB_BACC0 (B7JDU3), ADDB_BACC1 (Q73C24), ADDB_BACC2 (B7IL83), ADDB_BACC4 (B7HGP8), ADDB_BACC7 (B7HZR4), ADDB_BACCN (A7GM36), ADDB_BACCQ (B9ITE8), ADDB_BACCR (Q81GQ0), ADDB_BACCZ (Q63EM3), ADDB_BACHK (Q6HM44), ADDB_BACLD (Q65LK0), ADDB_BACMK (A9VJ01), ADDB_BACP2 (A8FBR0), ADDB_BACSU (P23477), ADDB_BACVZ (A7Z367), ADDB_CLOB8 (A6LPC3), ADDB_CLOBA (B2UX56), ADDB_CLOBB (B2THC7), ADDB_DESAP (B1I494), ADDB_DESHD (B8FXD8), ADDB_DESHY (Q24WW7), ADDB_DESRM (A4J4E2), ADDB_EXIS2 (B1YKM7), ADDB_GEOKA (Q5L264), ADDB_GEOTN (A4IKW6), ADDB_HELMI (B0TDI1), ADDB_LISIN (Q929A8), ADDB_LISMF (Q71X98), ADDB_LISMH (B8DF43), ADDB_LISMO (Q8Y510), ADDB_LISW6 (A0AL19), ADDB_LYSSC (B1HN89), ADDB_MOOTA (Q2RL78), ADDB_NATTJ (B2A611), ADDB_OCEIH (Q8ERW6), ADDB_PELTS (A5D1P4), ADDB_STAA1 (A7X0I1), ADDB_STAA2 (A6U073), ADDB_STAA3 (Q2FIA9), ADDB_STAA8 (Q2FZT6), ADDB_STAA9 (A5IRE4), ADDB_STAAB (Q2YWU2), ADDB_STAAC (Q5HHB8), ADDB_STAAE (A6QFH7), ADDB_STAAM (Q99VC4), ADDB_STAAN (Q7A6H5), ADDB_STAAR (Q6GIC2), ADDB_STAAS (Q6GAW0), ADDB_STAAT (A8Z072), ADDB_STAAW (Q8NXF0), ADDB_STACT (B9DIT7), ADDB_STAEQ (Q5HQJ5), ADDB_STAES (Q8CPU0), ADDB_STAHJ (Q4L4Y2), ADDB_STAS1 (Q49WA5), ADDB_SYMTH (Q67MD4), GAJB_BACC5 (P0DW48), GAJB_BACC6 (J8HQ06), HELD_BACSU (O32215), HELD_ECOLI (P15038), HMI1_YEAST (Q12039), PCRA_BACSU (O34580), PCRA_GEOSE (P56255), PCRA_LEUCI (Q9S3Q0), PCRA_STAA8 (Q53727), PCRA_STAAC (Q5HEL7), PCRA_STAAM (P64318), PCRA_STAAN (P64319), PCRA_STAAR (Q6GFF2), PCRA_STAAS (Q6G828), PCRA_STAAW (Q8NVT1), PCRA_STAEQ (Q5HN29), PCRA_STAES (Q8CRT9), RECB_BORBU (O51578), RECB_BUCAI (P57529), RECB_BUCAP (Q8K9A9), RECB_BUCBP (Q89AB3), RECB_CHLMU (Q9PLT8), RECB_CHLPN (Q9Z7G7), RECB_CHLTR (O84645), RECB_ECOLI (P08394), RECB_HAEIN (P45157), RECB_MYCS2 (A0QS29), RECB_MYCTO (P9WMQ2), RECB_MYCTU (P9WMQ3), REP_BUCAI (P57654), REP_BUCAP (O51889), REP_BUCBP (Q89A21), REP_ECOLI (P09980), REP_HAEIN (P44804), REP_SALTY (Q9L6S1), SRS2L_ARATH (D1KF50), SRS2_SCHPO (Q10213), SRS2_YEAST (P12954), UVRD1_MYCBO (P0A5A4), UVRD1_MYCLE (Q9CD72), UVRD1_MYCTO (P9WMQ0), UVRD1_MYCTU (P9WMQ1), UVRD2_MYCBO (P64321), UVRD2_MYCLE (P53528), UVRD2_MYCTO (P9WMP8), UVRD2_MYCTU (P9WMP9), UVRD_ECOLI (P03018), UVRD_HAEIN (Q02322), UVRD_MYCCT (P45612), UVRD_MYCGE (P47486), UVRD_MYCPN (P75437), UVRD_RICBR (Q1RIP8), UVRD_RICCN (Q92HZ6), UVRD_RICFE (Q4ULN5), UVRD_RICPR (Q9ZD95), UVRD_RICTY (Q68WT1), UVRD_SALTY (Q05311), Y340_MYCPN (P75438), YJCD_BACSU (O31626)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
9 sequences
FBH1_CHICK (F1ND48), FBH1_HUMAN (Q8NFZ0), FBH1_MOUSE (Q8K2I9), HELZ2_HUMAN (Q9BYK8), HELZ2_MOUSE (E9QAM5), JHS1_ARATH (A0A1P8ASY1), MAA3_ARATH (B6SFA4), YR568_MIMIV (Q5UR49), ZNFX1_CAEEL (E9P860)» more |
| PDB [Detailed view] |
39 PDB
1PJR; 1QHG; 1QHH; 1UAA; 1W36; 2IS1; 2IS2; 2IS4; 2IS6; 2PJR; 3K70; 3LFU; 3PJR; 3U44; 3U4Q; 4CEH; 4CEI; 4CEJ; 5LD2; 5MBV; 6SJB; 6SJE; 6SJF; 6SJG; 6T2U; 6T2V; 6WVK; 6ZCA; 6ZFB; 7MR0; 7MR1; 7MR2; 7MR3; 7MR4; 8B1R; 8B1T; 8B1U; 8SM3; 8U7I » more |