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PROSITE entry PS51252


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General information about the entry

Entry name [info] ANTISTASIN
Accession [info] PS51252
Entry type [info] MATRIX
Date [info] 01-AUG-2006 CREATED;
01-OCT-2013 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51252
Associated ProRule [info] PRU00582

Name and characterization of the entry

Description [info] Antistasin-like domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=26;
/DISJOINT: DEFINITION=PROTECT; N1=3; N2=24;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.7698648; R2=0.0045043; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=1273; N_SCORE=8.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=873; N_SCORE=6.7000; MODE=1; TEXT='RR';
/DEFAULT: M0=-35; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='C';  M= -61, 144, -77, -75, -73,  -9, -77, -79, -10, -71, -69, -64,  -6, -76,  -6, -62, -61, -68, -95, -80;
/M: SY='P';  M= -59, -77, -56,  39, -72, -27, -61, -10,   7,   2, -60, -12,  69,   4,  15,  30, -10, -64, -78, -69;
/M: SY='D';  M=  12, -77,  42,  41, -81, -65,  24, -77,  34, -77, -68,  32,  37,  29,  -7, -52, -13, -73, -83, -68;
/M: SY='I';  M= -16, -71, -75, -70,  20, -78,  14,  48, -61,  35,  18, -67, -75, -64,  33, -18,  18,   7, -73, -53;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='N';  M=   7, -74, -52,  39, -12, -67,   7, -15,  -9, -26, -59,  53,  -2,  -5,  41, -54,  -4,  -1, -77,  -8;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/I:         I=-24; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='R';  M=  -3,  18, -15, -16, -74,  -2, -62, -74,  23, -74, -66, -54,  27,   5,  57,   5,  42, -69,  40, -66;
/M: SY='M';  M= -62, -73, -67, -17, -58, -77, -63,  33,  47,  19,  66,   3, -72,   6,   7, -64, -58,  27, -76, -59;
/M: SY='Y';  M=  20, -76,  22,  35,  29,   1, -58, -17,   5, -64, -62, -57, -68,  34,  -5, -55,  -3, -64,  41,  42;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/M: SY='P';  M=   0, -80, -55,  49, -78, -68, -63, -25,   4, -30, -65, -62,  90, -52,  -6,   4, -10, -68, -78, -73;
/M: SY='Y';  M= -64, -73,  14, -63,  65,  -7,  64, -63, -63, -58,  15,  38, -75, -61, -64,  18, -19, -65, -57,  65;
/M: SY='G';  M= -50, -77, -61,  -2, -83, 101, -70, -90, -67, -85, -75, -50, -67, -64, -75, -50, -68, -84, -74, -78;
/M: SY='F';  M= -73, -75, -75, -75,  93, -79,  10, -53, -67, -14, -50,  -5, -83, -70,  -5, -69, -65, -58, -40,  90;
/M: SY='Q';  M=  16, -73,  -6,  39, -70, -68, -58, -60,  31,   8,  13,  -7, -67,  48,  18,  -8, -57,   1, -77, -64;
/M: SY='R';  M= -60, -72, -62, -55,   8, -72, -59, -61,  27,  -4,   6,  -2, -70,  23,  66, -16,  54, -18, -75, -58;
/M: SY='D';  M= -63, -78, 104, -38, -85,  19, -54, -85, -54, -84, -80,  35, -68, -54, -11, -16, -56, -82, -96, -71;
/M: SY='E';  M= -58, -75,   7,  53, -73, -69,   8, -67,  23,  -9, -62,  -6,  27, -47,  30,  31,  -9,  -7, -81, -66;
/M: SY='N';  M= -65, -76,  57,  23, -19, -65,  63, -75,  -9, -24, -65,  72, -70, -48,  29, -55, -57, -75, -84,   0;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='G';  M= -51, -76,  -4, -69, -82,  94, -66, -88, -63, -85, -74,  14, -68, -63,  -7,  -9, -64, -82, -76, -76;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='P';  M=  12, -78, -12,  58, -76, -66, -58, -71,  -9, -74, -66,  12,  67,  28, -15, -14, -15, -21, -77,  -8;
/M: SY='T';  M=   0, -67, -70, -69, -55, -72, -71,  51, -67,   4, -47, -61, -69, -66, -71,  12,  67,  24, -76,  12;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/M: SY='Q';  M=   0, -76,  11,  35, -73, -70, -57, -26,  48,  -1, -58, -53, -65,  59,  25, -54,  17, -64, -77, -64;
/M: SY='C';  M= -61, 154, -81, -81, -71, -77, -81, -78, -77, -69, -69, -67, -92, -85, -83, -64, -61, -66,-101, -82;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 37 in 14 different sequences
Number of true positive hits 37 in 14 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 6
Feature key [info] DOMAIN
Feature description [info] Antistasin-like
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
14 sequences

ANTA_HAEGH  (P16242), ANTA_HAEOF  (P15358), ANTA_HIRME  (P80302), 
ANTA_HYDVU  (P38977), BDEL_HIRME  (P82107), CRIM1_CHICK (Q8AWW5), 
CRIM1_DANRE (Q7T3Q2), CRIM1_HUMAN (Q9NZV1), CRIM1_MOUSE (Q9JLL0), 
GUAM_HIRNI  (P46443), KCP4_PINMG  (H2A0N9), PIGU_HIRNI  (P81499), 
THBI_THETS  (P82354), THST_THETS  (Q9NBW4)
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PDB
[Detailed view]
8 PDB

1BX7; 1BX8; 1C9P; 1C9T; 1EJA; 1HIA; 1SKZ; 3BG4