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Entry: PS51399

General information about the entry

Entry name [info] SEP
Accession [info] PS51399
Entry type [info] MATRIX
Date [info] 01-AUG-2008 CREATED; 10-MAY-2017 DATA UPDATE; 27-SEP-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC51399
Associated ProRule [info] PRU00732

Name and characterization of the entry

Description [info] SEP domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=66;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=61;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4773149; R2=0.0089281; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=8961.0605469; R2=1.4542329; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=675; H_SCORE=9943; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=451; H_SCORE=9617; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-47; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='K'; M= -33,-112,  23,  28,-108,-105,  23, -75,  42, -28,   0, -26,  26,  -4,  26, -41, -13,  -4,-116,-100;
/M: SY='V'; M= -23,-107,  13,  24, -57, -38,-101,  -9, -25, -40, -89,  -4,  -8,  10,   2, -51,  -7,  57,-117,-100;
/M: SY='P'; M= -18,   5,   7,  11, -76, -69,  24,  -5, -34, -36, -49, -45,  47, -10, -52,  11,  32,   9,   7, -99;
/M: SY='H'; M= -96,   2,-107,-101, -93,-116,  66,  34, -59, -23, -31,-100,-111, -95,  57,-100, -94,  58,-116, -30;
/M: SY='P'; M= -67,  -5, -47,   2,-103,-105,  25,  -5,  -2, -36, -92,  37,  41, -47,   6, -24,  35,  24,-119,-100;
/M: SY='I'; M= -98,-106,-120,-114, -81,-122,-112,  68,-112,  55, -17,-114,-114,-108,-113,-108, -93,  40,-110, -91;
/M: SY='T'; M= -63,-105, -94, -42,-100, -40,  67, -39,  22, -97, -92, -27,-101, -27,   3, -40,  74,  18, -14, -20;
/M: SY='F'; M=-102,-105,-120,-114,  77,-119,-104,  -4,-112,  57,  26,-114,-117,-111,-110, -68, -97,  17, -94, -74;
/M: SY='W'; M=-108,-126,-121,-112, -65,-110, -97, -99,-104, -57, -96,-119,-116,-102,-104,-110,-111,-109, 153,  99;
/M: SY='R'; M= -46,-110, -91, -27,-109,-101, -12,-110,  55, -49, -98,  10, -32,  15,  68,  28, -21,-106,-111, -43;
/M: SY='N'; M= -74,-107,  66,  -4,-116, -70, -82,-114, -40,-116,-107,  99,-104,  24, -91, -39, -40,-113,-128,-105;
/M: SY='G'; M= -84,-111, -50,-109,-117, 101, -27,-125,-104,-121,-110, -84,-103,-101,-111, -40,-102,-119,-109,-111;
/M: SY='F'; M=-108,-107,-122,-118, 109,-119,-103,  35,-113, -20, -11,-112,-118,-118,-111,-109,-100, -80, -81,   2;
/M: SY='T'; M= -28,  38, -96, -32, -36,-100, -99,  -3, -43, -62,   1, -88,-101,  34, -39,  48,  67,  -6,-116, -98;
/M: SY='V'; M= -92,-104,-119,-113, -40,-120,-115,  52,-110,   1,  35,-113,-112,-110,-112,-104, -89,  81,-115, -92;
/M: SY='D'; M= -81,-111,  84,  17,  19,  -6, -14,-113, -12,-112,-108,  66,-103, -87, -94, -88, -91,-112,-120, -97;
/M: SY='D'; M= -68,-113, 101,   9,-119,   6, -32,-116, -89,-116,-112,   8,-101, -31, -39, -16, -54, -55,-129,-105;
/M: SY='G'; M= -86,-111,   0, -31, -53,  94, -22,-121,-101, -65,-108, -19,-103, -98,-108, -28,-100,-116,-110,-108;
/I:         I=-22; MD=-57;
/M: SY='P'; M= -50,-120, -27,  54,-117, -35, -54,-110, -26,-115,-105, -99, 102, -55, -99, -26, -94, -49,-114, -59; D=-22;
/I:         I=-22; MI=0; MD=-57; IM=0; DM=-57;
/M: SY='F'; M= -56,-105,-118, -58,  84,-118,-102, -56,-109,  66, -73,-113,-118, -44, -42,-109, -99, -81, -91, -71;
/M: SY='R'; M=-100,-114,-100, -89,   3,-111,  11,-101,   1, -42,  44, -63,-109, -36,  99, -97, -98, -40,-103,  14;
/M: SY='P'; M= -20,-111,  23, -44,-109, -75, -31,-106,  -8, -25, -99, -17,  66, -59,  50,  41, -24,-104,  -7,-102;
/M: SY='Y'; M=-104,-110,-108,-107,  54,-113, -83, -28, -45,  18,  -7, -41,-116, -99, -17, -44, -98, -88, -74, 107;
/M: SY='D'; M= -44,-109,  81,  20,-113,  -6, -87,-114, -48,-113,-107,  33,-100,  30, -92,  33, -32,-110,-119, -11;
/M: SY='D'; M= -68,-112, 102, -25,-111, -49,   4, -48, -91, -53,-107,  -1,-102, -89, -98,  11, -90, -21,  42, -99;
/M: SY='P'; M= -13,-120,  -7,  -9,-117, -63,   8,-107, -94,-114, -37, -40, 115, -31,-104, -94, -49, -71,-115,-111;
/M: SY='E'; M=  27,-107, -13,  65,-107, -57, -92, -47, -20, -14, -29,  -3, -98,   7,  21,   5,  -7, -97,-113, -75;
/M: SY='N'; M= -55,  19, -77, -93,-109, -20, -21,-107, -86,-112,-102, 108,-104, -87, -94,  10,  40,-105,-126,-104;
/M: SY='Q'; M=  55,-105, -11, -12,-107, -96, -33, -23,  22, -64,  -4, -90,-101,  55,  17, -21,  -8, -32,-109, -33;
/M: SY='Q'; M=  21,-109, -17,  34, -45, -99, -22,-102,  11, -48,   2, -32, -23,  74,   5,  13, -56, -36,-110, -62;
/M: SY='F'; M=-103,  38, -24, -46, 103,-114,-102,  13,-108, -44, -42,-105,-115,-113,-109, -32, -29, -10, -85,  -7;
/M: SY='L'; M= -99, -22,-117,-111,  26, -55,-102,  12,-109,  74,  60,-112,-114,-104,-108,-108, -95,  -9,-102, -83;
/M: SY='E'; M=  12,-110,  31,  68,-114, -99, -87,-110,  -4,-108,-101,  24, -97,  42,  36, -26, -90, -51,-114,-102;
/M: SY='D'; M=  12,-105,  63,  29,-107, -30, -91, -46, -89,-104,  23,   0, -99, -85, -96,  54,  -4, -70,-116, -12;
/I:         I=-18; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='I'; M= -51,-107,-119,-115, -83,-121,-114,  85,-111,  29,   9,-112,-111,-108,-113,-106, -92,  39,-110, -91;
/M: SY='M'; M= -24,-107,  -6,   6,-100, -12, -88, -51,  33,  -3,  51,  49,-103,  -5,  39, -36, -32, -97,-110, -14;
/M: SY='R'; M=  12,-110,  37,  24,-113, -99, -88,-112,  46,-109,-100,   0, -99,  41,  51, -10, -29,-106,-113,-100;
/M: SY='G'; M= -61,-108, -96,-105,-114,  95,-101,-118,-100, -69, -40, -32,-102, -49, -58,  25, -95,-113,-109,-108;
/M: SY='E'; M= -57,-112, -48,  57,  40, -72, -35,  26, -84, -89, -89, -97,-104,  21,  40, -96, -96, -10, -94,  53;
/M: SY='C'; M=  34,  53,-111, -61,  41, -58,-104,  30,-105,   2, -81,-105,-111,-105,-107, -62, -77,  36, -42,  34;
/M: SY='P'; M= -53,-124,-100, -89,-119,-101,-103,-107, -57,-117,-104,-105, 126, -99, -56, -50, -92,-112,-113,-116;
/M: SY='P'; M=  -6,-107, -93,  23, -71, -66, -28, -42,   2,   4,  33, -93,  41,  18, -12,  35, -40, -39,   2,  34;
/M: SY='E'; M= -32,-109, -52,  92,-112, -50,  24,-110, -50,-107,-101, -86, -45,  14, -24,  39, -88, -38,-113,-101;
/M: SY='L'; M= -70,-103,-115,-109,  28, -71,   4,  21,-109,  78, -21,-111, -51,-104,-107,-106, -45, -51,-100, -25;
/M: SY='Q'; M=  -2,-108, -94,  17, -38, -71, -10, -58,  22,  27,  35, -93,-103,  57,  41, -48, -46, -37, -41, -24;
/M: SY='Q'; M=  -8,-109,  32,  -9,-113,  -9,   3,-110,   3,-110,-100,  38,  35,  55,  32,   7, -16,-107,-114,-100;
/M: SY='Q'; M=  -9,-105, -39, -31, -97, -55, -95,  -3,  27,  -6,  -6, -16, -48,  45,  25,  -6, -16,  40,-109, -25;
/M: SY='Y'; M= -18, -40,  36,   8,  40,  -3, -11, -98, -90, -58, -92, -22,   2,  -4,   8, -28, -56, -49, -88,  79;
/I:         I=-20; MD=-50;
/M: SY='P'; M= -50,-117,  -4, -34,  17,-105,  35,-105,  -3, -44, -11, -24,  90,   2,  34, -96, -61,-107,-109, -49; D=-20;
/I:         I=-20; MD=-50;
/M: SY='D'; M= -99,-116,  52, -42,-119,  46, -17, -59,   2, -59,-110,  47,-109, -38,  -3, -59, -27,-116,-125,-110; D=-20;
/I:         I=-20; MI=0; MD=-50; IM=0; DM=-50;
/M: SY='Q'; M= -64,-123, -67,  -5,-126,  -5,-106, -28,  -6,-118,-110, -22,-113,  71, -40, -20,  35,-113,-126,-114; D=-20;
/I:         I=-20; DM=-50;
/M: SY='G'; M= -40,-114,  36,  26, -51,  42, -37, -28, -49,-107,  13, -23,  24,  30, -12, -16, -42, -52,-115,-104; D=-20;
/I:         I=-20; DM=-50;
/M: SY='V'; M= -49, -26,-116,-110,   7,-116,-113,  49,-108,   9,   5,-109,-111,-108,-109, -66, -43,  80,-110, -88;
/M: SY='H'; M= -37,-108,  60,  -6,-108, -95,  65,-107, -86, -71,   6,  52,  45,  -2, -30,  18, -11,-106,-121, -44;
/M: SY='V'; M= -92,-101, -40, -63,  37,-116,-109,  13,-107,  33, -73, -47,-112,-108,-108,-101, -43,  78,-107, -84;
/M: SY='N'; M= -15,-106,  30,  23,-108, -48,  -8, -58,  40, -82, -99,  65, -99,   7,  13,   7, -16, -40,-115, -46;
/M: SY='V'; M= -49,-101,-112, -59, -82, -71,-105,  24,-105,  50,  41,-108,-110, -35,-105, -22, -88,  68,-110, -90;
/I:         I=-22; MD=-57;
/M: SY='E'; M= -48,-113, -18,  52, -38,-110,  13,  37,  -3, -96, -94,  -8, -40,  -8,  -9,  -6, -20,  -4,-112,   2; D=-22;
/I:         I=-22; MI=0; MD=-57; IM=0; DM=-57;
/M: SY='D'; M= -67,-109,  93, -46,-110, -97,  16, -27,  41,-105, -12,  -3, -38,  -1,   4, -12, -60, -33,-120, -97;
/M: SY='H'; M= -95,  46, -52, -53,-105,-101,  85, -65,  50, -69, -93,  11, -51,  21,  70, -18, -68,-105,-113, -89;
/M: SY='H'; M= -50,-103, -92, -57, -98, -34,  67, -60,   8,   4,  13, -32, -26, -13,  56,  14,  52, -52,-112, -90;
/M: SY='H'; M= -91,-107,  54,  49, -65, -17,  67, -18, -49,-104, -97,  40, -32,  29, -55,  15, -13, -50,-118, -94;
/M: SY='E'; M= -90,-109,  11,  94,-110, -59, -86,-102, -58, -65, -34, -10,  -9,  43, -52, -24, -21,  -5,-112,-101;
/M: SY='D'; M= -42,  22,  72,  16, -96, -99, -88,  -3,  12, -25, -34,  16,  -8, -36, -54, -12,  -1, -29, -24,  35;
/M: SY='Y'; M= -52,  48,-108,-105,  63,-109, -84, -42, -99, -50, -83,-104,-114, -13, -32, -99, -96,   6,  69, 105;
/M: SY='V'; M= -11,-102, -38,   4, -97,-101,   3,   0,  12, -35,   3, -11,  21,  20, -12,   4,  23,  49,-112, -95;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_09 which contains 555'594 sequence entries.


Total number of hits 25 in 24 different sequences
Number of true positive hits 25 in 24 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Feature key [info] DOMAIN
Feature description [info] SEP
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
24 sequences

NSF1C_BOVIN (Q3SZC4    ), NSF1C_CHICK (Q5ZK10    ), NSF1C_DICDI (Q54BQ5    ), 
NSF1C_HUMAN (Q9UNZ2    ), NSF1C_MOUSE (Q9CZ44    ), NSF1C_PONAB (Q5RBG3    ), 
NSF1C_RAT   (O35987    ), PUX3_ARATH  (Q9SUG6    ), PUX4_ARATH  (Q8RWU7    ), 
PUX5_ARATH  (Q7Y175    ), PUX6_ARATH  (F4IXN6    ), UBX11_HUMAN (Q5T124    ), 
UBX11_MOUSE (Q9D572    ), UBX11_RAT   (Q8R512    ), UBX1_EMENI  (P0C8Q0    ), 
UBX1_YEAST  (P34223    ), UBX2A_HUMAN (P68543    ), UBX2A_MOUSE (Q99KJ0    ), 
UBX2B_CHICK (Q5ZLK2    ), UBX2B_HUMAN (Q14CS0    ), UBX2B_MOUSE (Q0KL01    ), 
UBX2B_RAT   (P0C627    ), UBX2B_XENLA (Q0P3R5    ), UBX3_SCHPO  (Q9UT81    )
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PDB
[Detailed view]
2 PDB

1SS6; 1VAZ

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