PROSITE entry PS51399
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General information about the entry
| Entry name [info] | SEP |
| Accession [info] | PS51399 |
| Entry type [info] | MATRIX |
| Date [info] |
01-AUG-2008 CREATED;
13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51399 |
| Associated ProRule [info] | PRU00732 |
Name and characterization of the entry
| Description [info] | SEP domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=66; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=61; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4773149; R2=0.0089281; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=9002.6689453; R2=1.0923424; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=675; H_SCORE=9740; N_SCORE=8.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=451; H_SCORE=9495; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-47; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='K'; M= -33,-112, 23, 28,-108,-105, 23, -75, 42, -28, 0, -26, 26, -4, 26, -41, -13, -4,-116,-100; /M: SY='V'; M= -23,-107, 13, 24, -57, -38,-101, -9, -25, -40, -89, -4, -8, 10, 2, -51, -7, 57,-117,-100; /M: SY='P'; M= -18, 5, 7, 11, -76, -69, 24, -5, -34, -36, -49, -45, 47, -10, -52, 11, 32, 9, 7, -99; /M: SY='H'; M= -96, 2,-107,-101, -93,-116, 66, 34, -59, -23, -31,-100,-111, -95, 57,-100, -94, 58,-116, -30; /M: SY='P'; M= -67, -5, -47, 2,-103,-105, 25, -5, -2, -36, -92, 37, 41, -47, 6, -24, 35, 24,-119,-100; /M: SY='I'; M= -98,-106,-120,-114, -81,-122,-112, 68,-112, 55, -17,-114,-114,-108,-113,-108, -93, 40,-110, -91; /M: SY='T'; M= -63,-105, -94, -42,-100, -40, 67, -39, 22, -97, -92, -27,-101, -27, 3, -40, 74, 18, -14, -20; /M: SY='F'; M=-102,-105,-120,-114, 77,-119,-104, -4,-112, 57, 26,-114,-117,-111,-110, -68, -97, 17, -94, -74; /M: SY='W'; M=-108,-126,-121,-112, -65,-110, -97, -99,-104, -57, -96,-119,-116,-102,-104,-110,-111,-109, 153, 99; /M: SY='R'; M= -46,-110, -91, -27,-109,-101, -12,-110, 55, -49, -98, 10, -32, 15, 68, 28, -21,-106,-111, -43; /M: SY='N'; M= -74,-107, 66, -4,-116, -70, -82,-114, -40,-116,-107, 99,-104, 24, -91, -39, -40,-113,-128,-105; /M: SY='G'; M= -84,-111, -50,-109,-117, 101, -27,-125,-104,-121,-110, -84,-103,-101,-111, -40,-102,-119,-109,-111; /M: SY='F'; M=-108,-107,-122,-118, 109,-119,-103, 35,-113, -20, -11,-112,-118,-118,-111,-109,-100, -80, -81, 2; /M: SY='T'; M= -28, 38, -96, -32, -36,-100, -99, -3, -43, -62, 1, -88,-101, 34, -39, 48, 67, -6,-116, -98; /M: SY='V'; M= -92,-104,-119,-113, -40,-120,-115, 52,-110, 1, 35,-113,-112,-110,-112,-104, -89, 81,-115, -92; /M: SY='D'; M= -81,-111, 84, 17, 19, -6, -14,-113, -12,-112,-108, 66,-103, -87, -94, -88, -91,-112,-120, -97; /M: SY='D'; M= -68,-113, 101, 9,-119, 6, -32,-116, -89,-116,-112, 8,-101, -31, -39, -16, -54, -55,-129,-105; /M: SY='G'; M= -86,-111, 0, -31, -53, 94, -22,-121,-101, -65,-108, -19,-103, -98,-108, -28,-100,-116,-110,-108; /I: I=-22; MD=-57; /M: SY='P'; M= -50,-120, -27, 54,-117, -35, -54,-110, -26,-115,-105, -99, 102, -55, -99, -26, -94, -49,-114, -59; D=-22; /I: I=-22; MI=0; MD=-57; IM=0; DM=-57; /M: SY='F'; M= -56,-105,-118, -58, 84,-118,-102, -56,-109, 66, -73,-113,-118, -44, -42,-109, -99, -81, -91, -71; /M: SY='R'; M=-100,-114,-100, -89, 3,-111, 11,-101, 1, -42, 44, -63,-109, -36, 99, -97, -98, -40,-103, 14; /M: SY='P'; M= -20,-111, 23, -44,-109, -75, -31,-106, -8, -25, -99, -17, 66, -59, 50, 41, -24,-104, -7,-102; /M: SY='Y'; M=-104,-110,-108,-107, 54,-113, -83, -28, -45, 18, -7, -41,-116, -99, -17, -44, -98, -88, -74, 107; /M: SY='D'; M= -44,-109, 81, 20,-113, -6, -87,-114, -48,-113,-107, 33,-100, 30, -92, 33, -32,-110,-119, -11; /M: SY='D'; M= -68,-112, 102, -25,-111, -49, 4, -48, -91, -53,-107, -1,-102, -89, -98, 11, -90, -21, 42, -99; /M: SY='P'; M= -13,-120, -7, -9,-117, -63, 8,-107, -94,-114, -37, -40, 115, -31,-104, -94, -49, -71,-115,-111; /M: SY='E'; M= 27,-107, -13, 65,-107, -57, -92, -47, -20, -14, -29, -3, -98, 7, 21, 5, -7, -97,-113, -75; /M: SY='N'; M= -55, 19, -77, -93,-109, -20, -21,-107, -86,-112,-102, 108,-104, -87, -94, 10, 40,-105,-126,-104; /M: SY='Q'; M= 55,-105, -11, -12,-107, -96, -33, -23, 22, -64, -4, -90,-101, 55, 17, -21, -8, -32,-109, -33; /M: SY='Q'; M= 21,-109, -17, 34, -45, -99, -22,-102, 11, -48, 2, -32, -23, 74, 5, 13, -56, -36,-110, -62; /M: SY='F'; M=-103, 38, -24, -46, 103,-114,-102, 13,-108, -44, -42,-105,-115,-113,-109, -32, -29, -10, -85, -7; /M: SY='L'; M= -99, -22,-117,-111, 26, -55,-102, 12,-109, 74, 60,-112,-114,-104,-108,-108, -95, -9,-102, -83; /M: SY='E'; M= 12,-110, 31, 68,-114, -99, -87,-110, -4,-108,-101, 24, -97, 42, 36, -26, -90, -51,-114,-102; /M: SY='D'; M= 12,-105, 63, 29,-107, -30, -91, -46, -89,-104, 23, 0, -99, -85, -96, 54, -4, -70,-116, -12; /I: I=-18; MI=0; MD=-45; IM=0; DM=-45; /M: SY='I'; M= -51,-107,-119,-115, -83,-121,-114, 85,-111, 29, 9,-112,-111,-108,-113,-106, -92, 39,-110, -91; /M: SY='M'; M= -24,-107, -6, 6,-100, -12, -88, -51, 33, -3, 51, 49,-103, -5, 39, -36, -32, -97,-110, -14; /M: SY='R'; M= 12,-110, 37, 24,-113, -99, -88,-112, 46,-109,-100, 0, -99, 41, 51, -10, -29,-106,-113,-100; /M: SY='G'; M= -61,-108, -96,-105,-114, 95,-101,-118,-100, -69, -40, -32,-102, -49, -58, 25, -95,-113,-109,-108; /M: SY='E'; M= -57,-112, -48, 57, 40, -72, -35, 26, -84, -89, -89, -97,-104, 21, 40, -96, -96, -10, -94, 53; /M: SY='C'; M= 34, 53,-111, -61, 41, -58,-104, 30,-105, 2, -81,-105,-111,-105,-107, -62, -77, 36, -42, 34; /M: SY='P'; M= -53,-124,-100, -89,-119,-101,-103,-107, -57,-117,-104,-105, 126, -99, -56, -50, -92,-112,-113,-116; /M: SY='P'; M= -6,-107, -93, 23, -71, -66, -28, -42, 2, 4, 33, -93, 41, 18, -12, 35, -40, -39, 2, 34; /M: SY='E'; M= -32,-109, -52, 92,-112, -50, 24,-110, -50,-107,-101, -86, -45, 14, -24, 39, -88, -38,-113,-101; /M: SY='L'; M= -70,-103,-115,-109, 28, -71, 4, 21,-109, 78, -21,-111, -51,-104,-107,-106, -45, -51,-100, -25; /M: SY='Q'; M= -2,-108, -94, 17, -38, -71, -10, -58, 22, 27, 35, -93,-103, 57, 41, -48, -46, -37, -41, -24; /M: SY='Q'; M= -8,-109, 32, -9,-113, -9, 3,-110, 3,-110,-100, 38, 35, 55, 32, 7, -16,-107,-114,-100; /M: SY='Q'; M= -9,-105, -39, -31, -97, -55, -95, -3, 27, -6, -6, -16, -48, 45, 25, -6, -16, 40,-109, -25; /M: SY='Y'; M= -18, -40, 36, 8, 40, -3, -11, -98, -90, -58, -92, -22, 2, -4, 8, -28, -56, -49, -88, 79; /I: I=-20; MD=-50; /M: SY='P'; M= -50,-117, -4, -34, 17,-105, 35,-105, -3, -44, -11, -24, 90, 2, 34, -96, -61,-107,-109, -49; D=-20; /I: I=-20; MD=-50; /M: SY='D'; M= -99,-116, 52, -42,-119, 46, -17, -59, 2, -59,-110, 47,-109, -38, -3, -59, -27,-116,-125,-110; D=-20; /I: I=-20; MI=0; MD=-50; IM=0; DM=-50; /M: SY='Q'; M= -64,-123, -67, -5,-126, -5,-106, -28, -6,-118,-110, -22,-113, 71, -40, -20, 35,-113,-126,-114; D=-20; /I: I=-20; DM=-50; /M: SY='G'; M= -40,-114, 36, 26, -51, 42, -37, -28, -49,-107, 13, -23, 24, 30, -12, -16, -42, -52,-115,-104; D=-20; /I: I=-20; DM=-50; /M: SY='V'; M= -49, -26,-116,-110, 7,-116,-113, 49,-108, 9, 5,-109,-111,-108,-109, -66, -43, 80,-110, -88; /M: SY='H'; M= -37,-108, 60, -6,-108, -95, 65,-107, -86, -71, 6, 52, 45, -2, -30, 18, -11,-106,-121, -44; /M: SY='V'; M= -92,-101, -40, -63, 37,-116,-109, 13,-107, 33, -73, -47,-112,-108,-108,-101, -43, 78,-107, -84; /M: SY='N'; M= -15,-106, 30, 23,-108, -48, -8, -58, 40, -82, -99, 65, -99, 7, 13, 7, -16, -40,-115, -46; /M: SY='V'; M= -49,-101,-112, -59, -82, -71,-105, 24,-105, 50, 41,-108,-110, -35,-105, -22, -88, 68,-110, -90; /I: I=-22; MD=-57; /M: SY='E'; M= -48,-113, -18, 52, -38,-110, 13, 37, -3, -96, -94, -8, -40, -8, -9, -6, -20, -4,-112, 2; D=-22; /I: I=-22; MI=0; MD=-57; IM=0; DM=-57; /M: SY='D'; M= -67,-109, 93, -46,-110, -97, 16, -27, 41,-105, -12, -3, -38, -1, 4, -12, -60, -33,-120, -97; /M: SY='H'; M= -95, 46, -52, -53,-105,-101, 85, -65, 50, -69, -93, 11, -51, 21, 70, -18, -68,-105,-113, -89; /M: SY='H'; M= -50,-103, -92, -57, -98, -34, 67, -60, 8, 4, 13, -32, -26, -13, 56, 14, 52, -52,-112, -90; /M: SY='H'; M= -91,-107, 54, 49, -65, -17, 67, -18, -49,-104, -97, 40, -32, 29, -55, 15, -13, -50,-118, -94; /M: SY='E'; M= -90,-109, 11, 94,-110, -59, -86,-102, -58, -65, -34, -10, -9, 43, -52, -24, -21, -5,-112,-101; /M: SY='D'; M= -42, 22, 72, 16, -96, -99, -88, -3, 12, -25, -34, 16, -8, -36, -54, -12, -1, -29, -24, 35; /M: SY='Y'; M= -52, 48,-108,-105, 63,-109, -84, -42, -99, -50, -83,-104,-114, -13, -32, -99, -96, 6, 69, 105; /M: SY='V'; M= -11,-102, -38, 4, -97,-101, 3, 0, 12, -35, 3, -11, 21, 20, -12, 4, 23, 49,-112, -95; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 27 in 26 different sequences |
| Number of true positive hits | 27 in 26 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 2 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | SEP |
| Version [info] | 6 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
26 sequences
NSF1C_BOVIN (Q3SZC4), NSF1C_CHICK (Q5ZK10), NSF1C_DICDI (Q54BQ5), NSF1C_HUMAN (Q9UNZ2), NSF1C_MOUSE (Q9CZ44), NSF1C_PONAB (Q5RBG3), NSF1C_RAT (O35987), PUX3_ARATH (Q9SUG6), PUX4_ARATH (Q8RWU7), PUX5_ARATH (Q7Y175), PUX6_ARATH (F4IXN6), UBX11_HUMAN (Q5T124), UBX11_MOUSE (Q9D572), UBX11_RAT (Q8R512), UBX1_EMENI (P0C8Q0), UBX1_YEAST (P34223), UBX2A_HUMAN (P68543), UBX2A_MOUSE (Q99KJ0), UBX2A_RAT (D3ZID8), UBX2B_CHICK (Q5ZLK2), UBX2B_HUMAN (Q14CS0), UBX2B_MOUSE (Q0KL01), UBX2B_RAT (P0C627), UBX2B_XENLA (Q0P3R5), UBX3_SCHPO (Q9UT81), UBXN2_CAEEL (Q9N2W5)» more
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| PDB [Detailed view] |
5 PDB
1SS6; 1VAZ; 6OPC; 7R7S; 7R7T |