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Entry: PS51470

General information about the entry

Entry name [info] FG_GAP
Accession [info] PS51470
Entry type [info] MATRIX
Date [info] 01-DEC-2009 CREATED; 01-APR-2016 DATA UPDATE; 27-SEP-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC51470
Associated ProRule [info] PRU00803

Name and characterization of the entry

Description [info] FG-GAP repeat profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=61;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=61;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.6799066; R2=0.0073510; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=928; N_SCORE=8.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=520; N_SCORE=5.5; MODE=1; TEXT='R?';
/DEFAULT: M0=-19; D=-250; I=-250; B1=-200; E1=-200; MI=-155; MD=-155; IM=-155; DM=-155;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-155; BD=-155;
/M: SY='Q'; M= -18, -23,   1,   6, -33, -17,  10, -12, -12, -18, -25,  36, -28,  40,  -4,  -5,  -8, -22, -35, -26;
/I:         B1=-25; BI=-155; BD=-155;
/M: SY='R'; M= -10, -21,  -6, -13, -17,   0, -12,   0,  -6,   7,   0,  -7,   6, -13,  15,   2,   6,  11,  -9,   0;
/I:         B1=-50; BI=-155; BD=-155;
/M: SY='D'; M=  -9, -24,  19,  -1, -13,  -8, -21,  11, -13,   8, -14, -14,   7, -19,  -8,   3,  10,   2,  -3, -18;
/I:         B1=-70; BI=-155; BD=-155;
/M: SY='T'; M=  -3, -30,   2,   8,   0, -23,   9,  -6,  -3,  10, -15,  -8,   9,  10,  -5,  -9,  10,   1, -31,  -3;
/M: SY='G'; M=   2, -10, -18,  10, -21,  16,   9, -10,   1, -13, -10,  -3,   1,  -9,   0,  12,   6, -12, -32,  -3;
/I:         B1=-100; BI=-155; BD=-155; I=-44; MD=-27;
/M: SY='S'; M=  -6, -41,   9, -21, -21,  19,   8,   0, -14, -25, -33,  13,   6,  -7, -23,  30,  -7, -18, -68, -13; D=-44;
/I:         I=-44; MD=-27;
/M: SY='W'; M=  -7, -71,  -7, -16,  -5, -26,  36, -46,  -1, -40, -43, -28,  30,   8, -42,  20,  -4, -29,  40, -34; D=-44;
/I:         I=-44; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='E'; M= -22,  -2, -17,  33,  20,  30,  -6, -45, -42, -26, -26, -18, -14, -19, -34,  -8, -36, -43, -32, -33; D=-44;
/I:         I=-44; DM=-27;
/M: SY='E'; M= -28, -67,  14,  28, -13,  28,   1, -18,  -9, -41, -17,  12,   0,  25,  -1,   1, -21, -51, -68, -32; D=-44;
/I:         I=-44; DM=-27;
/M: SY='Q'; M= -29, -67, -14,   4, -10, -34,  28, -39,  32, -28,  10, -25,  36,  49,   5,  -8, -18, -22, -59,  19; D=-44;
/I:         I=-44; DM=-27;
/M: SY='G'; M=  -8, -49,  13,  20, -25,  24,  -1,  -5, -25, -27,  18, -15,  21,  -5,   3,   6,  12, -13, -64, -14;
/M: SY='Y'; M=  -1, -60,   2, -31,  16,  34,   7, -20, -45,   0,  34,  35, -13, -48, -42,   5, -30, -49,   7,  36;
/M: SY='S'; M=  16,  50, -18,  -9, -62,   7, -21, -52, -16, -46,  19, -26, -33,  46,   4,  53, -17, -53, -67, -44;
/M: SY='W'; M= -38, -67, -53, -19,   4, -16,  10, -53, -23, -31,  20, -21, -39,  44,  30,   4, -13, -55,  87,  69;
/M: SY='F'; M= -25, -18, -68, -31,  96, -39, -54, -16, -61,  29,   4, -62, -69, -20, -39, -45, -36, -29, -39, -18;
/M: SY='G'; M= -37, -64, -52, -64, -70,  99, -59, -77, -57, -73, -62, -38, -56, -55, -65, -37, -56, -56, -61, -65;
/M: SY='Y'; M=  -1, -44, -51, -32,  50, -24, -10, -11, -44,  -4,  -2, -53, -63,   8, -17,  12,  -9,   2,  33,  67;
/M: SY='S'; M=  28, -41, -29, -19, -60, -32, -50, -49, -45, -58, -53, -23, -37, -35, -42,  79,  41, -19, -70, -55;
/M: SY='V'; M=   8, -56, -68, -62, -38, -53, -61,  31, -61,  48,  25, -62, -64, -58, -62, -22, -20,  51, -65, -46;
/M: SY='A'; M=  41,  20,  22, -20, -31, -46,  36, -49, -21, -14, -46, -42, -56,   6,  11,  21,  18,   3, -69, -50;
/M: SY='G'; M=   9, -59, -54, -34,  18,  30, -31,  -5, -40, -11, -20, -18,  -8,   9,  -1,  25,   0,  15, -12,  -7;
/I:         I=-17; MD=-10;
/M: SY='H'; M=  -1, -63, -40, -34, -27,  13,  42, -29, -43,   9, -24,   0, -64,  -1, -50,  -2,  19,  11, -69,   1; D=-17;
/I:         I=-17; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='D'; M= -74, -88,  88, -11, -92, -72,   3, -92, -52, -90, -87, -30, -36, -38, -68, -63, -65, -89,-106, -57; D=-17;
/I:         I=-17; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='L'; M= -49, -47, -99, -92,  -8, -99, -89,  14, -90,  25,  -5, -93, -95, -88, -68, -86, -59,  12, -87, -68; D=-17;
/I:         I=-17; DM=-10;
/M: SY='N'; M= -64, -84,  49, -52, -89, -59, -62, -87, -56, -60, -83,  61, -82, -45, -60, -31, -18, -77,-105, -59; D=-17;
/I:         I=-17; DM=-10;
/M: SY='G'; M= -37, -77, -21, -36, -80,  43, -16, -77,   0, -63,  -6,   2, -56,  42,  -1, -13, -53, -55, -78, -69; D=-17;
/I:         I=-17; DM=-10;
/M: SY='D'; M= -46, -73,  80, -31, -80, -45, -49, -77, -15, -80, -73,  56,  19, -44, -41, -39, -36, -76, -91, -68; D=-17;
/I:         I=-17; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='G'; M= -42, -70, -30, -59, -64,  78, -37, -81, -23, -78, -68, -32, -63, -35, -19,  12, -25, -75, -71, -69; D=-17;
/I:         I=-17; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='Y'; M= -65, -80, -73, -34,  10, -70, -20, -23,  -1,   9, -15, -16, -81, -37, -31, -21, -52, -33,  22,  47; D=-17;
/I:         I=-17; DM=-10;
/M: SY='P'; M= -12, -67,  -2, -26, -55, -14,   1, -39, -52, -65, -28,  31,  49,   8, -60, -22,  48, -25, -79, -63; D=-17;
/I:         I=-17; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='D'; M= -51, -67,  90,  -5, -72, -19, -23, -71, -12, -59, -66,   2, -57,   3, -16,  24, -25, -58, -82, -39; D=-17;
/I:         I=-17; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='L'; M= -36, -58, -71, -65,  17, -72, -63,  44, -64,  52, -10, -67, -32, -62, -64, -59, -46,  51, -60, -33;
/I:         I=-76; MI=0; MD=-47; IM=0; DM=-47;
/M: SY='L'; M=  25, -55, -51, -60, -14, -63, -61,  26, -60,  49,   7, -62, -64, -41, -61, -38, -22,  46, -63, -45;
/M: SY='V'; M=  15, -55, -67, -62, -16, -56, -66,  39, -60,   8,  15, -60, -63, -59, -62, -30,  -1,  69, -67, -47;
/M: SY='G'; M=  -8,  75, -54, -62, -67,  87, -59, -73, -56, -69, -60, -41, -59, -56, -40, -14, -38, -65, -65, -65;
/M: SY='A'; M=  82, -31, -39, -48, -63,   5, -55, -53, -41, -51, -35, -46, -54, -46, -43,  25, -20, -27, -64, -58;
/M: SY='P'; M= -53, -74, -55, -34,   2, -58,  22, -45, -46, -23, -50, -59, 111, -29, -44, -52, -41, -11, -21, -31;
/M: SY='G'; M= -39, -62, -46, -43,   9,  46,   1, -48,  -5,  14,   6, -13, -60,   4,  41,  -9,  -1, -52,  20,   2;
/M: SY='Y'; M=  24, -61,   2,  15,   9, -15,   5, -34, -34, -36, -47, -34, -46,   6, -20,  24, -13, -11,  54,  58;
/I:         I=-33; MD=-21;
/M: SY='H'; M=  -6, -63,  14,  -5,  20,  17,  31, -29,  -2, -28,  11,   5, -29, -23, -35,  10, -12, -16,  -5,  30; D=-33;
/I:         I=-33; MD=-21;
/M: SY='W'; M= -17, -74,  -9,  -7, -24, -17,  -3, -30, -15, -38, -61,  14, -36,  -5, -22,   5,  -3, -14,  42, -12; D=-33;
/I:         I=-33; MD=-21;
/M: SY='R'; M=  -4, -76, -36, -21, -44, -20, -17, -19, -43, -30, -60, -34,  -2, -12,  14,  -5,  -3,   9, -83, -67; D=-33;
/I:         I=-33; MD=-21;
/M: SY='C'; M= -22,  26, -34, -36, -46, -21, -43, -55, -47, -30, -71, -29, -53,   6, -48, -37, -13, -13, -89, -12; D=-33;
/I:         I=-33; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='Y'; M= -40, -66,  29,   6,   8, -43, -23, -41,  -9,   2, -33,  20, -63,  20,  -1, -29,   9, -31, -54,  55; D=-33;
/I:         I=-33; DM=-21;
/M: SY='W'; M= -47, -69, -20,  19, -30, -30,  25, -42, -19, -13, -26,  -2,  13,  24,  44,  -2, -17, -41,  97, -21; D=-33;
/I:         I=-33; DM=-21;
/M: SY='T'; M=  12, -58, -25, -20, -37,   0,  -8, -18,   3, -31,  -6,  -6,  -3,  25,  17,  25,  34,   3, -65, -26;
/M: SY='G'; M= -39, -65, -29, -56, -67,  90, -54, -74, -38, -62, -43, -39, -57,  -7,  28, -39, -55, -56, -61, -35;
/M: SY='P'; M=  31, -27, -17, -44, -48,   3, -27, -11,  -5, -17,   4, -40,  47,  24,  12,   9,   8, -17, -65, -54;
/M: SY='V'; M= -21,  71, -70, -65, -12, -62, -68,  28, -62,   7, -17, -63, -67, -46, -64, -47, -37,  74, -71, -48;
/M: SY='Y'; M= -12, -62, -62, -60,  45, -43,  -7,   9, -42,  11, -34, -58, -67, -39, -30,  -9, -36,   9,   1,  89;
/M: SY='I'; M= -16, -60,   3, -27, -38, -50,  -3,  32,   7,  19, -12, -30, -60,   5,   9,  -4,   4,  28,  17, -14;
/M: SY='C'; M=  -9,  75, -36, -33,  42, -64, -36,  10, -31,   7,  -8, -43, -67, -29, -57, -43, -21,  19, -46,  62;
/M: SY='P'; M= -33, -62,   6, -11, -39, -18,  24, -19, -13, -13, -19,  34,  41,  22,  11,  14,  20, -40, -63,  15;
/M: SY='Q'; M=   3, -33, -13, -30, -37,  28, -28,  -4, -23,  -8, -25,  10,  18,  28, -43,  18,  -4,  12,  16, -17;
/M: SY='N'; M= -11, -60,  19,  12, -44,  -3,  26, -36,   3, -52, -29,  38,  -6,  22,   8,  29,  21, -28, -70, -47;
/M: SY='Q'; M=  -8, -60,  -2,   0,   5,  -1, -14, -16,   4,  12,  10, -13,  -3,  36, -13,  13,  10, -12, -15, -38;
/I:         E1=-100; IE=-155; DE=-155;
/M: SY='Q'; M=  -9, -19,   2,   2, -15,  12,   1,  -7,   2,  -8, -11,  14, -12,  14,  11,   9,   1, -21, -33, -26;
/I:         E1=-70; IE=-155; DE=-155;
/M: SY='G'; M= -11, -30,  -4, -15,  15,  15,  -7,  -2, -13,  -3,   0,  -1,   4,  -7,   8,   2,   5,   0, -29, -11;
/M: SY='C'; M=  -1,  17,  -3,   5,  -4,  -8, -16,   5, -10,   2, -15,   2,   6,   6,  -8,   5,   8, -12,   4,  -5;
/I:         E1=-30; IE=-155; DE=-155;
/M: SY='P'; M=  -5,  -4,   7,   1,   5,  -6, -11, -16,  -3,  -3,  -6,   0,  22,   5,   6,   8,   4, -15, -15, -15;
/I:         E1=-15; IE=-155; DE=-155;
/M: SY='P'; M=  -6,  10,   0,   2,  -6, -14,  -8, -11,  -1,  -8,   0,  -4,  16,  11,   6,  12,   2, -14,   6,   4;
/I:         E1=0; IE=-155; DE=-155;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_09 which contains 555'594 sequence entries.


Total number of hits 423 in 62 different sequences
Number of true positive hits 423 in 62 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.69 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 7
Feature key [info] REPEAT
Feature description [info] FG-GAP
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
62 sequences

INA1_CAEEL  (Q03600    ), ITA10_HUMAN (O75578    ), ITA11_HUMAN (Q9UKX5    ), 
ITA11_MOUSE (P61622    ), ITA1_DROME  (Q24247    ), ITA1_HUMAN  (P56199    ), 
ITA1_MOUSE  (Q3V3R4    ), ITA1_RAT    (P18614    ), ITA2B_HUMAN (P08514    ), 
ITA2B_MOUSE (Q9QUM0    ), ITA2B_PAPCY (P53711    ), ITA2_BOVIN  (P53710    ), 
ITA2_DROME  (P12080    ), ITA2_HUMAN  (P17301    ), ITA2_MOUSE  (Q62469    ), 
ITA3_BOVIN  (F1MMS9    ), ITA3_CRIGR  (P17852    ), ITA3_DROME  (O44386    ), 
ITA3_HUMAN  (P26006    ), ITA3_MOUSE  (Q62470    ), ITA4_DROME  (Q9V7A4    ), 
ITA4_HUMAN  (P13612    ), ITA4_MOUSE  (Q00651    ), ITA4_XENLA  (Q91687    ), 
ITA5_DROME  (Q9W1M8    ), ITA5_HUMAN  (P08648    ), ITA5_MOUSE  (P11688    ), 
ITA5_XENLA  (Q06274    ), ITA6_CHICK  (P26007    ), ITA6_HUMAN  (P23229    ), 
ITA6_MOUSE  (Q61739    ), ITA7_HUMAN  (Q13683    ), ITA7_MOUSE  (Q61738    ), 
ITA7_RAT    (Q63258    ), ITA8_CHICK  (P26009    ), ITA8_HUMAN  (P53708    ), 
ITA8_MOUSE  (A2ARA8    ), ITA9_HUMAN  (Q13797    ), ITA9_MOUSE  (B8JK39    ), 
ITAD_HUMAN  (Q13349    ), ITAD_MOUSE  (Q3V0T4    ), ITAD_RAT    (Q9QYE7    ), 
ITAE_HUMAN  (P38570    ), ITAE_MOUSE  (Q60677    ), ITAL_BOVIN  (P61625    ), 
ITAL_HUMAN  (P20701    ), ITAL_MOUSE  (P24063    ), ITAM_HUMAN  (P11215    ), 
ITAM_MOUSE  (P05555    ), ITAV_BOVIN  (P80746    ), ITAV_CHICK  (P26008    ), 
ITAV_HUMAN  (P06756    ), ITAV_MOUSE  (P43406    ), ITAX_HUMAN  (P20702    ), 
ITAX_MOUSE  (Q9QXH4    ), PAT2_CAEBR  (A8X3A7    ), PAT2_CAEEL  (P34446    ), 
PHLD_BOVIN  (P80109    ), PHLD_HUMAN  (P80108    ), PHLD_MOUSE  (O70362    ), 
PHLD_RAT    (Q8R2H5    ), PLDG_DICDI  (Q86AV9    )
» more

UniProtKB/Swiss-Prot
False negative sequences
10 sequences

CRAC1_HUMAN (Q9NQ79    ), CRAC1_MOUSE (Q8R555    ), CRAC1_XENTR (Q0V9M0    ), 
ITFG2_BOVIN (Q27969    ), ITFG2_HUMAN (Q969R8    ), ITFG2_MOUSE (Q91WI7    ), 
ITFG2_PONAB (Q5RBH8    ), TIP_HUMAN   (Q8TB96    ), TIP_MOUSE   (Q99KW9    ), 
TIP_RAT     (Q8R4E1    )
» more

PDB
[Detailed view]
58 PDB

1JV2; 1L5G; 1M1X; 1TYE; 1U8C; 2VC2; 2VDK; 2VDL; 2VDM; 2VDN; 2VDO; 2VDP; 2VDQ; 2VDR; 3FCS; 3FCU; 3IJE; 3K6S; 3K71; 3K72; 3NID; 3NIF; 3NIG; 3T3M; 3T3P; 3V4P; 3V4V; 3VI3; 3VI4; 3ZDX; 3ZDY; 3ZDZ; 3ZE0; 3ZE1; 3ZE2; 4CAK; 4G1E; 4G1M; 4MMX; 4MMY; 4MMZ; 4NEH; 4NEN; 4O02; 4UM8; 4UM9; 4WJK; 4WK0; 4WK2; 4WK4; 4Z7N; 4Z7O; 4Z7Q; 5E6R; 5E6S; 5E6U; 5ES4; 5HDB
» more

View entry in original PROSITE format
View entry in raw text format (no links)
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