To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Entry: PS51486

General information about the entry

Entry name [info] REKLES
Accession [info] PS51486
Entry type [info] MATRIX
Date [info] 01-APR-2010 CREATED; 10-MAY-2017 DATA UPDATE; 22-NOV-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC51486
Associated ProRule [info] PRU00819

Name and characterization of the entry

Description [info] REKLES domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=96;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=91;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3533337; R2=0.0063739; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=13283.6904297; R2=4.4532375; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=965; H_SCORE=17581; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=651; H_SCORE=16183; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-23; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='A'; M= 56,-42,-39, -7,-46,-18,-42,-39,-38,  4,  9,  2,-44,-34,-43, 41, 18,-33,-56,-44;
/M: SY='A'; M= 56,-45, -2,-38,-48,  6, 16,-12,-38,-18, 15,-34,-15,-36, -6, 19, 14,-33,-57,-43;
/M: SY='L'; M= -2,-49,-53,-47,  2, -7,-46, 29,-11, 48, 24,-47,  2,-42, -7,  5,-36,-22,-49,-34;
/M: SY='E'; M=-18,-54,-21, 76,-55, 19,-36,-54, 14,-21,-45,-33,-38,-20,  2, -8,  7,-49,-56,-48;
/M: SY='Q'; M= 29,-51,-29, 27,-58,-11,  1,-53,-26,-52,-43, 29,  0, 64,  1, 30,-31,-47,-57,-45;
/M: SY='H'; M=-24,-49,-43, -5,-35, -4, 55, -2,-18, 38,-24,-38,-50,-36, -6, 15, 15, 11,-57,-35;
/M: SY='R'; M=-13,-55, -2,-32,-49, 18,-36,-47, -1,  8,-37, -2, 31, 27, 57,  4,-37,-46,-54,-44;
/M: SY='H'; M= 15,-52, 22, 59,-55,-42, 63,-57,-26,-52,-45,-28,-41,-21, 16, 35,-32,-50,-62,-40;
/M: SY='R'; M=  2,-53,  1, 18,-55,-17,-33,-55, 32,-53,-44, 23,-45,-23, 69,-30, 20,-48,-57,-44;
/M: SY='H'; M=-41,-52, -6,-41,-31,-16, 63,-29,-41, 48, 20,-40, 21,-37, -2, 13,-37,-33,-52,  9;
/M: SY='E'; M= 28,-47,-25, 60,-53, -6,-38,-49,-30,-21,-43, -7,-40,-24,-38, 44, 14,-42,-58,-47;
/M: SY='S'; M=  7,-46, -1, -4,-49,-37,-39,-43,-32,-20,-41,-29, 15,-30, 14, 65, 34,-16,-60,-45;
/M: SY='G'; M= 27,-50,-38,  2,-53, 50,-46, -9,-40,-49,-42,  4, 46,-39,-48,-27, 27,-16,-56,-51;
/M: SY='E'; M= 19,-53,  4, 67,-55,-12,-38,-40,-28,-45,-41,-36,  8, 41,-35,-32,-36, 21,-58,-48;
/M: SY='P'; M=-11, 19,-41,-35,-58,-14,-42,-53,-32,-57,-47,-38, 89,-35, 27, 45,-30,-51,-58,-52;
/M: SY='P'; M= 15,-54,-42, -6,-54,-14,-48,-38,-40,-48,-41,-43, 92,-42,-49,-32, 33, 11,-59,-53;
/M: SY='E'; M=-11,-53,-23, 70,-55, 11,-37,-49, 31,-50,-45,-33,-39,-21,  1, 13,-34,  1,-56,-48;
/M: SY='K'; M=-41,-56,-30, 18,-56,-48, 49,-58, 86,-54,-42,-26,-41, 12, 10,-35,-37,-54,-53,-39;
/M: SY='K'; M=-42,-58,-36,-21,-57,-50,-32,-58, 74,-54,-42,-29,-45, 43, 68,-35,-39,-53,-51,-42;
/M: SY='M'; M= 51,-45,-44,-39,  0, -1, 48,-37,-40,-14, 55,-36,-47,  4,-42, 27,-32,-21,-53,-35;
/M: SY='S'; M= 27,-45,-43,-39,-44,  7,-42,-33,-38, 11, -5,-34,-47,  5, -6, 57,-10, 12,-56,-42;
/I:         I=-25; MD=-63;
/M: SY='R'; M= -8,-55,-49,-43,-48,-19,-45,-41,-31, 18,-36,-42,-55,  4, 52, 20, 17,-13,-61,-46; D=-25;
/I:         I=-25; MI=0; MD=-63; IM=0; DM=-63;
/M: SY='M'; M=-12, 19,-51,-48,-39,-38,-47,-30,  4, 36, 37, -1,-55,-44,-46,  2, 31,-11,-61,-44; D=-25;
/I:         I=-25; DM=-63;
/M: SY='S'; M= 42,-46,-38, -2, -5,  6,-42,-15, 16,-48,-42,-31,  1,-31,-36, 56,-26,-38,-53,-43;
/M: SY='E'; M=-37,  4, 33, 61,-59,-44, -2,-58, 31,-55,-48, 24,  5, 27,-26, 12,-21,-54,-61,-47;
/M: SY='E'; M=-19,-54, 17, 65,-53,  5, 23,-49, 18,-22,  9,-31,-14,-23,-31,  7, -4,-27,-59,-44;
/M: SY='Q'; M=-34, 18, 14, 41,-58,-12, 24,-56,-10,-53,-45, 37,-43, 59,-31, 33, -2,-52,-61,-44;
/M: SY='Q'; M=-33,  7,-10,  0,-55, 27, 23,-48,-30,-23,-39,  4, -1, 77,-33, 27,-34,-17,-56,-42;
/M: SY='R'; M= -3,-55,-40,-32,-55, 18,-36,-56, 26,-54,-43,-32, 14,-11, 77, -6,  7,-50,-54,-45;
/M: SY='L'; M=  9,-50, 13,-39,-35,-13,-40, 10,  3, 46,-23, 20,-53,-36, 26,-39,-37,-28,-54,-39;
/M: SY='M'; M=  2,-47,-52,-47,-32,-18, 17,  7,-27, 39, 57,-14, -3,-42,-46,  0,-34, 28,-55,-36;
/M: SY='Q'; M=-34, -6,-14,  2,-59,  2, 18,-49,-26,-49,-39, -5,  0, 92,-28, 24, -3,-18,-56,-41;
/M: SY='Q'; M= 21, 16,-36,-30,-53, -5, 32,-47,-27,-18, -7, 31,  2, 66, 24, -1,-35,-29,-57,-41;
/M: SY='A'; M= 51,-45,  0, 12,-55, -8,-41,-48,-35,-50,-44,-32, 24, 11,-41, 40, 20,-40,-57,-48;
/M: SY='F'; M=  3,-50, -7,-42, 43, 13,-44,  0,-41,  8,-30,  0, 13,  7, -7,-15,  3, 13,-47,-31;
/M: SY='Q'; M=-12,-57,-32,  9,-61,-20,-30,-55, 26,-51,-40,-28,-44, 91, 33, 20,-35,-52,-52,-42;
/I:         I=-14; MD=-36;
/M: SY='Q'; M=-16,-62,  7, 25,-61, -5, 37,-59,-25,-53, 14,-34,-49, 60, 40, -2,-43,-56,-62,-44; D=-14;
/I:         I=-14; MI=0; MD=-36; IM=0; DM=-36;
/M: SY='N'; M=-15,-55,  8,-40,-63,  8,-39,-62,  2,-65,-55, 65,-54,-37, -5, 32, -3,-58,-71,-55; D=-14;
/I:         I=-14; DM=-36;
/M: SY='S'; M=  7, 18,-53,-51, 42,-48,-49,-36,-50, 26,-33,-44,-56,-47,-52, 43, 14,-36,-51,-33; D=-14;
/I:         I=-14; DM=-36;
/M: SY='S'; M= -3,-51,-54,-52, 39, 11,-49,-34,-51, 27,-33,-44,-57,-47,-53, 44,-36, -8,-51,-34; D=-14;
/I:         I=-14; DM=-36;
/M: SY='S'; M= 24,-48,-39,-43,-56,  3,-42,-52,-41,-54, 15, 30,-49,-36,-46, 65,  1,-46,-65,-51; D=-14;
/I:         I=-14; DM=-36;
/M: SY='M'; M=-37,-52, 10,-42,-47,  9,-37,-38,-41,-15, 84, 33, 28,-37,-46, 33,-33,-41,-61,-44; D=-14;
/I:         I=-14; DM=-36;
/M: SY='A'; M= 45,-47, 17, -6,-54, -2,-45,-46,-10,-30,-44,-33,-46,-36,-43, 31, 32,-21,-62,-49; D=-14;
/I:         I=-14; DM=-36;
/M: SY='R'; M= 12,-51,-38,-35,-54,-14,-39,-52, 36,-25,-44, 22,-48,-29, 41, 37,  8,-47,-59,-47; D=-14;
/I:         I=-14; DM=-36;
/M: SY='Q'; M=-39,-55, 18, -1,  8,  2, 60,-42, -4, 11, 13,-30,-48, 71,-31, -8,-39,-45,-53,-31;
/M: SY='I'; M=-43,-49,-47,-51,  4,-55, 16, 48,-48, 47,-16, 45,-56,-45,-49,-44,-36, 11,-54,-32;
/M: SY='P'; M=-14,-57,-38,-32,-59,-40,-42,-51, 14,-58,-47, 18, 97,-36,-40, 28, -4,-51,-58,-54;
/M: SY='M'; M=-14,-50,-51,-47,-34,  2,-42, 22,-42, 31, 75, -3, 20,-40,  4,-12,-36, -1,-53,-37;
/M: SY='N'; M=-14,-50,  1, 29,-50, 13,-34,-47, 28,-11, 12, 51,-44,-27,  0,  4, 14,-45,-59,-45;
/M: SY='T'; M=-12,-49, -2,-39,-37,  2,-39, 25,  3, -2,-32, 19,-47,-35, 15, 14, 39,-30,-51, 21;
/M: SY='R'; M= -2,-51,-50,-41,  2,-17,-43,-24, 16, 38,-24,-45, -2,-36, 47,-42,-38, 23,-51,-36;
/M: SY='S'; M=-11,-51,-44,-38, 12,  7,-43, 24, 31,-10,-34,-35, 14,-34, 16, 40,-31,-18,-50,-37;
/M: SY='N'; M=  3,-49,  0,-44,-38,-47,-38,-31,-40, 44, 12, 62,-56,-40, -7,-37, -4,-35,-62,-43;
/M: SY='H'; M=-16,-53,-40,-10,-44, 23, 44,-41,-38, 31,-32, 36,-54,  5,  5,  1,-39,-43,-60,-41;
/I:         I=-29; MD=-75;
/M: SY='N'; M=-14,-57,-35,  5,-60,-44,-38,-56, 12,-29,-48, 43, 24, 34, 15, 33,-35,-54,-63,-51; D=-29;
/I:         I=-29; MI=0; MD=-75; IM=0; DM=-75;
/M: SY='E'; M=-41,-64, 13, 80,-67, 28,-40,-69,-30,-62,-57,-36,-42,  9,-39,-38,-45,-62,-63,-57; D=-29;
/I:         I=-29; DM=-75;
/M: SY='M'; M=-15,-54, 29,-11,-51,-24,-39,-41,-36,-39, 72, 24,-52,-36, 20,  6, 10,-15,-66,-46; D=-29;
/I:         I=-29; DM=-75;
/M: SY='Q'; M=-43, 19,-43,-33,-49,-12,-38,-46, 23, 18,-35,  2,-54, 53, 51, -9,-41,-46,-57,-44;
/M: SY='Q'; M= -6,-54, 23,-35, 52,-14,-40,-42,-39,-16, 18,-36,-52, 56,-41, 20, -6,-43,-47,-29;
/M: SY='Q'; M=-41,-60, 35, 25,-56, 22,-39,-13,-35, -9,-41,  1,  5, 61,-39,-36,-41,-16,-60,-48;
/I:         I=-13; MD=-33;
/M: SY='V'; M=-17,-57,-57,-57,-47,-20,-57,-31,-56, 22,-37, -5, -8,-53,-59, 21,  2, 27,-70,-52; D=-13;
/I:         I=-13; MD=-33;
/M: SY='A'; M= 48,-56,-57,-53,-64,-45,-59,-16,-54,-57,-53,-48,-59,-49,-58, 45,-38,-14,-71,-60; D=-13;
/I:         I=-13; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='R'; M=-12,-74,-62,-54,-73,-64, 12,-69,-40,-71,-62,-54,  9,-47, 52, 17,-54,-29,-79,-62; D=-13;
/I:         I=-13; DM=-33;
/M: SY='N'; M=-53,-59,-45,-55,-50,-56,-46,-41,-47, 24, 13, 63,-65,-48,-10,-35, 11,-25,-74,-53; D=-13;
/I:         I=-13; DM=-33;
/M: SY='N'; M=-46,-64,-43,-52,-67, 48,-49,-69, 19,-36,-59, 53,-60,-46,-46,-14,-47,-67,-70,-62; D=-13;
/I:         I=-13; DM=-33;
/M: SY='T'; M=-20,-56, -9,-53,  1,-62, 11, 19,-54, 18,-34,-46,-57,-53,-58,-40, 56,-32,-65,-43; D=-13;
/I:         I=-13; DM=-33;
/M: SY='G'; M= 15,-53,-44, -8,-59, 41,-51,-56,-46,-28,-51,-10,-51,-43,-53, 30, 32,-49,-65,-56; D=-13;
/I:         I=-13; DM=-33;
/M: SY='D'; M= 21,-55, 35, 18,-62, -3,-45,-56,-42,-56, 14,  1,-16,-39,-49, 20, 18,-50,-69,-55; D=-13;
/I:         I=-13; DM=-33;
/M: SY='N'; M=-43,-53,  4,-38,-57,-21,-33,-56, -4,-29,-50, 84,-54,-33, 17, 16, -2,-56,-72,-52; D=-13;
/I:         I=-13; DM=-33;
/M: SY='G'; M= -9,-54,-42,-52,-60, 79,-48,-59,-47,-61,-52, 14,-50,-44,-54, 16,-41,-19,-58,-56;
/M: SY='E'; M=  2,-56, 35, 55,-54,-50,-42, 22, 11,-46,-44,-34,-43,-29,-37,  5,  7,-37,-62,-49;
/M: SY='Q'; M=  2,-53,  1,-31,-61,  0,-35,-56,-33,-58,-48, 52, 11, 57,-38, 39, -3,-52,-63,-50;
/M: SY='S'; M=-27,-51,-36,-29,-60,-36,-36,-56,-31,-56,-47,-27,-46, 73,-34, 78,-24,-51,-60,-45;
/M: SY='I'; M=-46,-54,-66,-60,-26,-67,-53, 62,-58, 50, 56,-59,-59,-51,-57,-56,-42,-11,-54,-35;
/M: SY='N'; M=-37,-49,-39,-48,-43,-47,-45, 40,-43,-34,-33, 59,-52,-42,-49, 22, 26, 31,-66,-45;
/M: SY='M'; M=-36,-49,-65,-57,-34,-63,-54, 11,-53,-16, 82,-57,-57,-51,-53,-49,-35, 73,-64,-39;
/M: SY='S'; M=  0, 22,-31,-39,-56,-32,-36,-54,-36,-58,-50, 61,-48,-32,-42, 70,  4,-48,-68,-50;
/M: SY='M'; M=-42,-50,-65,-58,-28,-64,-51, 26,-55, 43, 73,-59,-59,-50,-54,-53,-39, 43,-57,-36;
/M: SY='E'; M=-42,-62, 19, 96,-65,-56,-34,-66,-23,-58,-55,-36,-37,-16,-33,-38,-41,-58,-63,-54;
/M: SY='I'; M=-46,-54,-66,-61,  5,-69,-57, 62,-59, 49, 10,-60,-60,-55,-59,-56,-41, 15,-52,-34;
/M: SY='N'; M=-44,-49, 17,-35,-59,-32,-24,-58,-29,-65,-52,108,-54,-31,-38,-26,-28,-60,-78,-53;
/M: SY='G'; M=-30,-57,-45,-56,-64, 91,-51,-71,-50,-67,-56,-31,-49,-47,-57, -2,-47,-64,-55,-58;
/M: SY='I'; M=-40,-52,-59,-58,-35,-65,-63, 71,-54,-20,-22,-50,-53,-54,-58,-42, 40, 42,-61,-41;
/M: SY='M'; M=-39,-51,-47,-39,-43,-55,-46, -6, 46,-10, 56,-39,-49,  5,-31,-37, 40, 28,-59,-42;
/M: SY='Y'; M=-53,-63,-52,-55,  0,-59,-18,-38,-47,-34,-31,-53,-65,-42,-44,-47,-47,-43, -8,121;
/M: SY='Q'; M=-10,-50,-36, -3,-56,-42,-39,-49,-32,-30,-42,-30,-44, 67,-36, 48, 51,-44,-61,-45;
/M: SY='G'; M=-30,-58,-45,-57,-64, 93,-52,-72,-51,-67,-56,-31,-49,-48,-58,-30,-49,-65,-55,-59;
/M: SY='V'; M=-33,-48,-60,-56,-37,-20,-62, 18,-54,-23,  8,-53,-57,-54,-56,  3,-32, 79,-66,-43;
/M: SY='L'; M=-48,-51,-64,-56,-23,-67,-49,-14,-54, 78,-10,-63,-65,-50,-11,-58,-44,-22,-52,-35;
/M: SY='F'; M=-18,-51,-63,-59, 84,-61,-49,-20,-55,-24,-30,-55,-62,-60,-55,-47, -7, 41,-32, 34;
/M: SY='A'; M= 79,-45, -7,-40, -7,-33,-50,-47,-44,-48,-43,-43,  6,-41,-49,-25,-34,-35,-55,-48;
/M: SY='Q'; M=-24,-56,-33,-32,-53,-13, 20,-49,-26,  4,-38, 63,-53, 66, 30,-33,-39,-51,-61,-43;
/M: SY='P'; M= 22,-55, 29,-34,-57,  8,-45,-44, 19,-51,-45, -9, 40,-38,  6, -7,-36, 14,-62,-51;
/M: SY='P'; M= -1,-63,-41, 11, -9, 16, 18,-58,-40,-59,-50, -3, 73, 27,-47,-13,-42,-57,-59,-50;
/M: SY='P'; M=  8,-55,-46,-47,-53, 31,-50,-14,-44,-15,-42, 13, 38,-45, -7, -7, 23, -5,-63,-53;
/M: SY='S'; M=-20,-53,-49,-46,-48,-50, 15, 16,-42,-25,-37,-41, 18,-42, 10, 44, 13, 26,-65,-46;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_11 which contains 556'196 sequence entries.


Total number of hits 13 in 13 different sequences
Number of true positive hits 13 in 13 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] REKLES
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
13 sequences

ARI3A_DANRE (A2BEA6    ), ARI3A_HUMAN (Q99856    ), ARI3A_MOUSE (Q62431    ), 
ARI3A_XENLA (Q6GQD7    ), ARI3A_XENTR (Q5XGD9    ), ARI3B_HUMAN (Q8IVW6    ), 
ARI3B_MOUSE (Q9Z1N7    ), ARI3C_HUMAN (A6NKF2    ), ARI3C_MOUSE (A6PWV5    ), 
CFI1_CAEEL  (O02326    ), DRI_CIOIN   (Q4H3P5    ), DRI_DROME   (Q24573    ), 
DRI_STRPU   (Q8MQH7    )
» more


View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission