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PROSITE entry PS51490


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General information about the entry

Entry name [info] KHA
Accession [info] PS51490
Entry type [info] MATRIX
Date [info] 01-APR-2010 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51490
Associated ProRule [info] PRU00823

Name and characterization of the entry

Description [info] KHA domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=83;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=78;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.5729909; R2=0.0088077; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=10850.1416016; R2=2.6952662; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1298; H_SCORE=14349; N_SCORE=14.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=446; H_SCORE=12052; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-23; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='R';  M=-46,-62,-42,-29,-57,-55,-34,-61, 36,-56,-44,-35,  7,-21, 96,-40,-43,-56,-55,-44;
/M: SY='V';  M=-35, 65,-61,-57,-35,-62,-62, 26,-54, -5,-24,-54,-58,-56,-57,-44,  3, 73,-67,-43;
/M: SY='T';  M=-32,-45,-42,-42, -1,-20,-48, 14, -4,-38,-37,-31,-44,-40,-43, 36, 73,  1,-60,-40;
/M: SY='I';  M=-10,-51,-63,-59,-30,-64,-61, 69,-56, 22,-17,-57,-56,-54,-58,-49,-36, 48,-57,-38;
/M: SY='H';  M=-42,  7,-45,-44, 61,-48, 82,-39,-43,-10,-31,-36,-54,-39,-41, 32,-37,-41,-33, 62;
/M: SY='C';  M=-37, 70,-45,-15,-48, 18,-44,-40, 20,-14, 41,-40, 49,-37, 21,-12,-37, -2,-57,-47;
/M: SY='N';  M=-43,-55,-31,-34, 21,-14, 54,-50,-32,-49,-40, 67, 58, 31,-10,-33,-35,-53,-50, 23;
/M: SY='H';  M=-41,-57,-29, 35, -5, 21, 92,-55,-29,-28,-38, 15, -9,  0, 19,-35,-42,-54,-54, 17;
/I:         I=-19; MD=-47;
/M: SY='P';  M=-28,-74,-55,-45,-73,-58, 10,-62, -6,-69,-58,-54, 81, 13,-53,  5,-48,-32,-72,-64; D=-19;
/I:         I=-19; MD=-47;
/M: SY='W';  M=-64,-80,-21,-61,-15,-64,  5,-77,-60,-76,-71, 36,-76,  2,-64, 12,-59,-80, 84,-52; D=-19;
/I:         I=-19; MI=0; MD=-47; IM=0; DM=-47;
/M: SY='E';  M=-69,-84,-59, 28,-18,-82,  6,-67,-57,-19,-62,-67,  3,-13,-10,-66,-22,-36,-82,-65; D=-19;
/I:         I=-19; DM=-47;
/M: SY='H';  M=  5,-52,  6,-33,-53, 48, 58,-58,-13,-54,-44,-26,-45, 36, -4, 36,-34,-52,-55, -4;
/M: SY='R';  M=-38,-54, 33,-10,  2,-12,-37, -6, -5,-45,-41, -3, -9,-29, 62, 22,-11, -1,-56,-39;
/M: SY='S';  M=-34,-53, 27, 11,-54, 21, 24,-48,  0,-49,  3, -3,  0, 16, 26, 32, -6, -8,-60,-43;
/M: SY='H';  M=  8, 29,-34, 22,-46,-21, 53,-40,  9,  6,-35, 23, 19,-31,  2, -1,-35, -3,-60,-40;
/M: SY='G';  M=-14,-54,-41,-46,-59, 83,-46,-63,  9,-60,-50,-29,  9,-40,-11,-28, -2,-57,-53,-53;
/M: SY='K';  M=  9, 18,-39,-27,-51,-47,-40,-41, 79,-46,-39,-32,-45,-24, 27,-34,-34, 17,-54,-44;
/M: SY='V';  M=-38,-46,-62,-55,-24,-63,-53, 15,-55, 59,-12,-59,-59,-52,-54,-50,-35, 60,-55,-35;
/M: SY='V';  M=-37, 19,-62,-57, 10,-63,-56, 48,-54, 23, 38,-55,-56,-53,-54,-48,-34, 60,-54,-33;
/M: SY='W';  M=-43,-53,-47,-45, 23,-49, 35,-12,-44, 32,-28, 28, 40,-43,-47, -5,-10,-12, 88,-26;
/M: SY='L';  M=-41,-48,-61,-54,-23,-63,-50, 31,-52, 64, 20,-58,-59,-48,-17,-52,-38, 35,-52,-33;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='P';  M=-43,-67,-43,-32,-62,-45, 23,-53, -7,-61,-47,-46,114,-41,-47,-16,-36,-57,-58,-55;
/M: SY='D';  M=-15,-54, 56, 26,-54,  9, 45,-57, -7,-55,-48, 23,-44, 16,-35, 12,  3,-54, 49,-40;
/M: SY='T';  M=-25,-41, -1,-35,-50,-34,-38,-45,-34,-50,-44, 24,-40,-32,-40, 68, 69,-38,-64,-44;
/M: SY='M';  M=-43,-51,-64,-57, 14,-61,-49, 58,-52, 36, 78,-55,-54,-47,-52,-52,-39,  0, 51,-26;
/M: SY='E';  M= 12,-56, 51, 71,-61,-45,-33,-58, -8,-55,-49,-29, 10, 32,-32,-11,-35,-52,-60,-49;
/M: SY='E';  M=-39,-57, 18, 79,-57,-16,-32,-56, 21,-18,-45,  2,-39, 23,  3,-34,-38,-52,-57,-47;
/M: SY='L';  M=-45,-47,-63,-55, 13,-64,-47,-10,-56, 79, -7,-61,-62,-50,-53,-55,-41, -2,-47,-29;
/M: SY='L';  M=-42,  8,-59,-51, 16,-61,-48,  8,  5, 64, 15,-55,-58,-47,-45,-51,-39, 21,-49,-30;
/M: SY='K';  M= -7, 28, -7, 20,-54,-43,-35,-49, 48,-50,-43, 16,-44, 28, 27, 23, -5,-13,-58,-45;
/M: SY='I';  M= 20,-48,-54,-48,-33,-52,-50, 56, -5, 17, 43,-46,-50,-43,-46,-10,  0, 23,-54,-37;
/M: SY='A';  M= 74, 32,-47,-42,-51, 22,-49,-13,-43,-43,-39,-39,-46,-40,-48, -6,-32, -3,-55,-49;
/M: SY='S';  M= 19,-48,-31, 18,-56, 36,-37,-55,-31,-55,-47, 18,-43,  7,  6, 58,-27,-48,-57,-48;
/M: SY='K';  M=  5,-53,-31, 40,-52,-47, 16,-19, 49,-27,-38,-32,-43, 40, 20,  3,-35, -8,-55,-42;
/M: SY='K';  M=-40,-56,-32,  5,-57,-48,-34,-56, 82,-53,-42,-27,-42, 44, 33,-32,  2,-51,-52,-43;
/M: SY='F';  M=-49,-49,-62,-57, 83,-61,-41,-19,-55, 50,-18,-57,-63,-55,-52,-52,-43,-26,-26, 44;
/M: SY='G';  M=-31,-55,-34, 14,-60, 76,-41,-62,  3,-59,-48,  2,-44, 41,-38,-27, -9,-57,-53,-51;
/M: SY='M';  M=-39, 28,-50,-48, 44,  7,-45,  6, 14, 13, 47, 14,-54,-44,-42,-42,-37, 30,-47,-28;
/M: SY='H';  M= 23,-52, 14,-29,-46,-41, 53,-46,-28,-46,-38,-30,  3, 46, 27, 25, -9,-10,-53, 21;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='P';  M= 48,-51,-43,-37,-54, 18,-45, -6,-11,-27,-40, -9, 70, -6,-45, -5,-34,-38,-55,-50;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='T';  M= 15,-44,-38,-35,  1,-41,-41,-39, 37, -7,-36,  0,-44,-32, -8, 33, 53,-17,-55,-39;
/M: SY='R';  M=-40, 22,-39, -9,-51,-24,-36,-48, 50,-25,-39,-33,-48,  3, 73,-35, 11,-13,-55,-42;
/M: SY='V';  M=-36,-47,-62,-56,-27,-64,-58, 45,-54, 34, 13,-57,-57,-53,-55,-48,-33, 69,-58,-36;
/M: SY='F';  M=-41,-48,-61,-56, 49,-62,-46,  6,-53, 44, 12,-57,-60,-52,-52,-50,-37, 48,-39, 34;
/M: SY='N';  M=-34,-45,  8,-37,-10,-10,-34,-38,-35,  1, 32, 66,-46,-34,-41, 29, 47,-38,-61,-40;
/M: SY='E';  M= 30,-50,  8, 52,  3,-19, 13,-45, 31,-16,-40,-33,-42,-26,-30,-12, -7,-20,-54,-40;
/M: SY='D';  M=-40,-56, 77, 56,-62,-43,-30,-61,  3,-58,-53, 35,-41,  9,-32, -4,-33,-57,-68,-48;
/M: SY='G';  M= 15,-52,-38,-46,-60, 83,-43,-62,-42,-60,-50, 27,-46,  7,-48,-25,-41,-56,-54,-53;
/M: SY='A';  M= 71,-43,-43,-40,-54, 33,-45,-48,-37,-49,-42,-35,-44,-36,  1, 12,  2,-36,-54,-49;
/M: SY='E';  M=-39,-58,-17, 85,-55,-53, 25,-52,  3,-24,-43,-34,-38, 25, 20,-35,-39,-19,-57,-45;
/M: SY='I';  M=-37,-51,-63,-59,-29,-66,-64, 79,-55,-13,-16,-55,-54,-54,-58,-48,-33, 62,-57,-36;
/M: SY='D';  M=-41,-56, 87, 42,-56,-45,-33,-52,-30, -7,-47,-21,-43, 14,-38, -5, -1,-50,-68,-46;
/M: SY='D';  M=-42,-58, 97, 40,-65,-44,-31,-63,-29,-60,-57,-17,-42, 16,-37, -9,-35,-59,-73,-48;
/M: SY='I';  M=-16,-49,-62,-56,-27,-62,-57, 62,-54, 29, 29,-55,-55,-51,-55,-48,-34, 53,-55,-35;
/M: SY='D';  M= 24,-50, 60,  6,-55,-38, 16,-52,-27,-50, 18, 41,-46,-28, 27, 15,-31,-47,-65,-44;
/M: SY='V';  M= 16, 55,-54,-10,-33,-53,-50,-12,-48, 24, 55,-51,-54,-46,-50,-41,-34, 56,-59,-39;
/M: SY='I';  M=-42,-53,-63,-60,-26,-67,-60, 85,-56, 27,-12,-56,-54,-53,-58,-51,-36, 27,-52,-34;
/M: SY='R';  M=-42,-59,  0,  4,-55,-51, 19,-60, 14,-53,-43,-31,-49, 14, 93, -5,-40,-54,-56,-40;
/M: SY='D';  M=-46,-60, 97, 30,-67,-11,-34,-66,-33,-64,-61, 11,-46,-31,-42,-35,-38,-62,-78,-52;
/M: SY='N';  M=-37,-54, 33, -2,-62, 59,-35,-64,-37,-65,-54, 74,-49,-36,-45,-29,-37,-62,-66,-55;
/M: SY='D';  M=-11,-60, 94,  3,-66,-45, 23,-63,-33,-60,-55,-20,-47, 40,-39,-34,-39,-60,-75,-47;
/M: SY='H';  M=-43,-55,-41,-36,-47,-52, 84,-16, 33,-39, 39, -1,-10,-31, 20,-37, 17,  7,-65,-34;
/M: SY='L';  M=-47,-50,-65,-57,-21,-67,-49,  5,-59, 79, -9,-64,-64,-51,-56,-58,-43,-19,-52,-34;
/M: SY='Y';  M=-48,-55,-12,-55, 65,-61,-37, 13,-52,-10,-27,-53,-62,-52,-51,-49,-43, 23,-24, 80;
/M: SY='V';  M=  5,-48,-63,-56, 39,-59,-54, 15,-55, 32, 23,-57,-59,-54,-55,-47,-38, 51,-50,-30;
/M: SY='V';  M=-35,-48,-54,-51, 17,-53,-52, 31,-50, 19,-25,-45,-54,-47,-52, 35, 19, 40,-56,-35;
/M: SY='S';  M=-34,-52, -9, 22,-46,-20,-38,-45,  0,-29,-43, -1, 17,  8,-38, 41, 36,-16,-55, 19;
/M: SY='D';  M=-39,-60, 39, 25,-64, 39, 11,-64, 13,-61,-53, -4, 10, 23,-37,-10, -9,-60,-63,-51;
/M: SY='E';  M=-43,-62, 34, 51,-65,  7,  6,-65,-10,-60,-53,-33,-47, 36, 18,-11, -4,-60,-65,-51;
/M: SY='W';  M=-12,-57, 16,  3,-14, -1, 10, -2,-12,-50,-46,-36, -1, -1,-45, 30, 16,-21, 34,-44;
/M: SY='F';  M=-22,-59, 24,-14, 46,-18, 18,-46, 26,-26,  7,-10,  8, 15,-38,-43,-44,-23,-52,-32;
/M: SY='R';  M=-48, 16, 11,  1, -4,-56,-39,-48, 11, -9,-42,  8,  8,  8, 36,-43,-16,-24,-52, 30;
/M: SY='D';  M=-11,  6, 34,  5,-52,-23,-44,-18, 13,-19, 26, 13,-52,-38, -7,-38, 12,  5,-67,-49;
/M: SY='P';  M=-11,-59,  4,-14,-15, -2, 11, -8,-45,-14,-46,-41, 35,-44,-12, 25,  9,-46,-65,-49;
/M: SY='K';  M=  6,-61,  7,  9,-55,  6,-47,-54, 14, -2,  1,  4,-57,-40, -9,-15,-46,-52,-63,-10;
/M: SY='Q';  M=-24,-59,  3,-41,-61,-14,  3,-56,-40,-28, -1, 11,-55, 38, -2, 21, 32,-53,-71,-52;
/M: SY='W';  M=-49,-64,-48,  5,-60,-59,-52,-56,  1,-58,  4, -4, 21,-42, 23, -2, 33,-28, 48,-53;
/M: SY='F';  M= -1,-63,-12,-22, 23,  4,-55,-19,-23, -6,-47,-12, 12,-51,-13,-21, -5,-48,-61,-47;
/M: SY='D';  M=-28,-68, 19, -5,-12,-22,  4,-61,-15,-32,-57,  0,  6,-47,-11, 15,-48,-27,-74,-55;
/M: SY='D';  M=-24,-69, 16,  2,-63, -3,  7,-26,-21,-10,  5,-48,  6, -1,-55,-16,-16,-55,-74,-58;
/M: SY='S';  M=  0,-68,-13,-51,-64,-58, 11,-64,-22,-40,-58,-13, 14,  2,-56, 16, 11,-61,-73, -3;
/M: SY='E';  M= -1,-72,-51, 16,-77,-62,  9,-69,-54,-72,-65,  8, -6,  7,-59,  7,-15,-32,-84,-67;
/M: SY='Q';  M=-68,-77,-17,-61,-11,-78,-62,-55,-60, 20,-50, -1,-79, 26,-16,-63,-13,-59,-77,-59;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 20 in 20 different sequences
Number of true positive hits 20 in 20 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] KHA
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
20 sequences

AKT1_ARATH  (Q38998), AKT1_ORYSI  (P0C550), AKT1_ORYSJ  (Q0JKV1), 
AKT2_ARATH  (Q38898), AKT2_ORYSJ  (Q75HP9), AKT3_ORYSJ  (Q8H569), 
AKT5_ARATH  (Q9SCX5), AKT6_ARATH  (Q8GXE6), GORK_ARATH  (Q94A76), 
KAT1_ARATH  (Q39128), KAT1_ORYSJ  (Q6K3T2), KAT2_ARATH  (Q38849), 
KAT2_ORYSJ  (Q5QNI1), KAT3_ARATH  (P92960), KAT4_ORYSJ  (Q652U9), 
KAT6_ORYSJ  (A2ZX97), KCTD9_HUMAN (Q7L273), KCTD9_MOUSE (Q80UN1), 
KOR1_ORYSJ  (Q653P0), SKOR_ARATH  (Q9M8S6)
» more

PDB
[Detailed view]
12 PDB

7CAL; 7FCV; 7T4X; 7WM1; 7WM2; 7WSW; 7XUF; 8JEC; 8JET; 8JEU; 8WTZ; 8WUI