Entry: PS51491

Forthcoming changes to the profile format
General information about the entry

Entry name [info] TAU_MAP_2
Accession [info] PS51491
Entry type [info] MATRIX
Date [info] MAY-2010 (CREATED); OCT-2013 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC00201
Associated ProRule [info] PRU00824

Name and characterization of the entry

Description [info] Tau and MAP proteins tubulin-binding repeat profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=31;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=28;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.3458040; R2=0.0151269; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1362.45777; R2=7.81926; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=341; N_SCORE=8.5; H_SCORE=3513; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=209; N_SCORE=6.5; H_SCORE=2997; MODE=1; TEXT='?';
/DEFAULT: M0=-23; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='I'; M=-11,-32,-24, -9, -4,-50,-18,-23,  7,-30,-14, -1,-31,-25,-15,-19,-26,-17,-16,-13,-57,-20;
/M: SY='Z'; M=-12, -2,-72,  3, 17,-64,-33,-17,-11,-19,-35,-21, -9,-26, 15,-25,-20,-13, -8,-52,-54, 20;
/M: SY='I'; M=-13,-41,-41,-38,-33,  1,-41,-43, 36,-51, -2, -2,-32,-42,-44,-41,-30,-14,  7,-56,-23,-43;
/M:         M=-26,-32,-53,-34,-33,-23,-40,-12,-10,-33,-21,-18,-21,-24,-27,-24,-27,-25,-24,-48,-29,-30;
/M:         M=-10, -8,-32,-11,-13,-36,-22,-12,-26,-27,-37,-28, -3,-24,-16,-26, -1, -7,-32,-36,-25,-14;
/M: SY='Z'; M=-15, -6,-76, -6,  5,-83,-29,-23,-40, -3,-50,-32,-11,  2,  1,-15,-13,-21,-25,-52,-67,  8;
/M: SY='K'; M=-32,-29,-82,-39,-32,-58,-46,-34,-24, 13,-16, 10,-21,-24,-15, -6,-24,-19,-28,-66,-59,-21;
/M: SY='P'; M=-20,-40,-54,-44,-36,-43,-43,-25,-16,-33, -6,-14,-36,  4,-19,-16,-22,-26,-20,-40,-61,-27;
/M: SY='D'; M=-12, 40,-90, 48, 36,-88,-16, -4,-40,-18,-62,-52, 22,-34, 13,-40,-14,-22, -8,-15,-70, 26;
/M: SY='L'; M=-44,-58,-75,-73,-65, 21,-70,-33,  1,-58, 31, -2,-46,-53,-46,-55,-46,-42,-16,-26, -2,-50;
/M: SY='K'; M=-18,-13,-49,-13,-16,-66,-21,-32,-27, 15,-40, -7, -5,-26,-22, -2, -4, -1,-35,-45,-52,-19;
/I:         I=-14; MD=-29;
/M: SY='N'; M=-13, 26,-58, 21,  3,-53,-13,  3,-27,  6,-44,-29, 29,-27, -6,-15,  0, -5,-27,-35,-36,  2; D=-14;
/I:         I=-14; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='I'; M=  4,-34,-15, -9, -8,-34,-11,-42, 28,-46, -6,  2,-32,-28,-36,-44,-24, -6,  6,-31,-46,-34;
/M: SY='Q'; M=-22, -9,-74,-16, -6,-73,-41, -1,-33,  7,-39,-17, -9,-18, 28, 12,-17,-14,-39,-63,-64, 16;
/M: SY='S'; M= 10,  0,-10,-10,-20,-40,  0,-30,-40,-20,-50,-30, 10,  0,-30,-10, 40, 20,-30,-30,-40,-20;
/M: SY='K'; M=-40,-10,-90,-20,-20,-90,-40,-30,-40, 60,-50,  0,  0,-40,-10, 20,-20,-10,-50,-70,-60,-10;
/M: SY='I'; M=-22,-49,  6,-47,-42,-31,-48,-48, 30,-57,-21,-17,-41,-46,-55,-40,-29,-19, 15,-41,-31,-55;
/M: SY='G'; M=  0,-10,-60,-10,-20,-60, 60,-50,-60,-40,-70,-50,-10,-30,-40,-60,  0,-20,  0,  0,-80,-20;
/M: SY='S'; M= 10,  0,-10,-10,-20,-40,  0,-30,-40,-20,-50,-30, 10,  0,-30,-10, 40, 20,-30,-30,-40,-20;
/M: SY='M'; M=-21,-34,-71,-44,-40,-33,-45,-41, -4,-12,  2, 17,-24,-35,-25,-28,-18, -1, -8,-61,-47,-31;
/M: SY='D'; M=-14, 24,-85, 30, 22,-85, -6,-22,-42, -8,-65,-44, 13,-37, -5,-37,-12,-20,-10,-13,-68, 13;
/M: SY='N'; M=-10, 40,-60, 30,  0,-50,-10, 20,-30,  0,-50,-40, 50,-30,-10,-20, 10,  0,-40,-50,-30,  0;
/M: SY='I'; M=-14,-39,-56,-43,-33,-13,-48,-46, 32,-34, 10, 19,-31,-39,-31,-33,-30,-13, 16,-70,-41,-32;
/M: SY='K'; M=-26,  1,-70, -9,-18,-66,-33, -4,-35, 23,-47,-19, 13,-32, -8,  1, -9, -3,-40,-63,-43, -8;
/M: SY='H'; M=-42, -8,-44,-21,-28,-17,-56, 63,-46,-36,-40,-52, 11,-31,  3,-13,-32,-40,-42,-36,  9, -3;
/M: SY='E'; M=-13,-21,-46, -3,  4,-62,-20,-17, -6,-18,-19, -2,-23,-25,  3,-21,-28,-17,-22,-39,-59, -4;
/M: SY='P'; M=  8,-26,-48,-34,-26,-66,-24,-24,-44,-40,-40,-46,-26, 57,-12,-24,  2,-14,-24,-88,-74,-18;
/M: SY='G'; M= -8,-10,-66,-12,-20,-66, 41,-46,-56,-21,-66,-41, -8,-32,-34,-45, -4,-18, -9,-13,-76,-18;
/M: SY='G'; M=  0,-10,-60,-10,-20,-60, 60,-50,-60,-40,-70,-50,-10,-30,-40,-60,  0,-20,  0,  0,-80,-20;
/M: SY='G'; M=  0,-10,-60,-10,-20,-60, 60,-50,-60,-40,-70,-50,-10,-30,-40,-60,  0,-20,  0,  0,-80,-20;
/M: SY='N'; M=-16, 13,-69,  6,  1,-66,-24,  5,-36,  4,-43,-25, 16,-21, 15, -5, -5, -9,-40,-61,-50, 13;
/I:         E1=0; IE=-105; DE=-105;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 72 in 19 different sequences
Number of true positive hits 72 in 19 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 4
Feature key [info] REPEAT
Feature description [info] Tau/MAP
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
19 sequences

MAP4_BOVIN  (P36225), MAP4_HUMAN  (P27816), MAP4_MOUSE  (P27546), 
MAP4_RAT    (Q5M7W5), MTAP2_HUMAN (P11137), MTAP2_MOUSE (P20357), 
MTAP2_RAT   (P15146), TAU_BOVIN   (P29172), TAU_CAPHI   (O02828), 
TAU_GORGO   (Q5YCW0), TAU_HUMAN   (P10636), TAU_HYLLA   (Q5YCV9), 
TAU_MACMU   (P57786), TAU_MOUSE   (P10637), TAU_PANTR   (Q5YCW1), 
TAU_PAPHA   (Q9MYX8), TAU_PONPY   (Q5S6V2), TAU_RAT     (P19332), 
TAU_SPECI   (Q6TS35)
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