Entry: PS51496

General information about the entry

Entry name [info] CVC
Accession [info] PS51496
Entry type [info] MATRIX
Date [info] JUN-2010 (CREATED); OCT-2013 (DATA UPDATE); JUN-2010 (INFO UPDATE).
PROSITE Doc. [info] PDOC51496
Associated ProRule [info] PRU00829

Name and characterization of the entry

Description [info] CVC domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=54;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=49;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.9688087; R2=0.0082100; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-4790.41176; R2=25.51471; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=918; N_SCORE=8.5; H_SCORE=17050; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=674; N_SCORE=6.5; H_SCORE=12407; MODE=1; TEXT='?';
/DEFAULT: M0=-14; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A   B   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y   Z
/I:         B1=0; BI=-105; BD=-105;
/M: SY='K'; M=-18,  0,-67,  0, -1,-68,-18,-11,-18, 55,-38,  8,  9,-18,  8, 36,  2,  3,-28,-42,-48, -1;
/M: SY='C'; M=-18,-28, 28,-35,-38,-50,-32,-18,-13,-18,-41,-24,-23,-21,-31,  0, -3,-12,-11,-52,-25,-33;
/M: SY='W'; M=-70,-60,-90,-80,-90,  0,-80,-30,-60,-40,-20,-50,-50,-70,-60, 20,-30,-60,-80,180,-10,-70;
/M: SY='G'; M= 10,  0,-40,  0,  0,-60, 60,-30,-30,-20,-50,-40,  0,-10,-20,-40, 10,  0,-20,-80,-60,-10;
/M: SY='R'; M= -7, -2,-45, -6, -6,-55,  7, -1,-25, 13,-43,-21,  3, -8, -1, 14,  0, -5,-26,-37,-50, -2;
/M: SY='S'; M= 10, 10,  0,  0,  0,-40, 10,-10,-20,  0,-40,-20, 10, 10,-10,-10, 20, 20,-10,-30,-30,-10;
/M: SY='T'; M= 10,  6,-13,  0, -4,-40,  6,-14,-11,  0,-31,-16,  6,  6,-10,-10, 20, 29, -6,-43,-30,-10;
/M: SY='I'; M= -6,-27,-28,-27,-22,-13,-24,-28, 42,-18, 15, 19,-17,-24,-26,-20,-13,  0, 39,-69,-28,-22;
/M: SY='M'; M=-20,-30,-60,-40,-30,  0,-40,-30, 20, 10, 40, 80,-20,-30,-10,-10,-20,-10, 20,-50,-30,-20;
/M: SY='A'; M= 30,  0,-30,  0,  0,-40, 10,-20,-10,-20,-20,-20,  0, 10,-10,-20, 10, 10,  0,-70,-40,  0;
/M: SY='E'; M=  0, 30,-70, 40, 50,-70,  0,  0,-30,  0,-40,-30, 20,-10, 30,-20,  0,-10,-20,-90,-50, 40;
/M: SY='Y'; M=-40,-40,  0,-50,-50, 70,-60,  0,-20,-50,-20,-30,-20,-60,-50,-50,-30,-30,-30,-10,110,-50;
/M: SY='G'; M= 10,  0,-40,  0,  0,-60, 60,-30,-30,-20,-50,-40,  0,-10,-20,-40, 10,  0,-20,-80,-60,-10;
/M: SY='L'; M=-20,-40,-70,-50,-40, 20,-50,-30, 20,-40, 70, 40,-40,-30,-20,-40,-40,-20, 20,-20,-20,-30;
/M: SY='Y'; M=-40,-40,  0,-50,-50, 70,-60,  0,-20,-50,-20,-30,-20,-60,-50,-50,-30,-30,-30,-10,110,-50;
/M: SY='G'; M= 10,  0,-40,  0,  0,-60, 60,-30,-30,-20,-50,-40,  0,-10,-20,-40, 10,  0,-20,-80,-60,-10;
/M: SY='A'; M= 30,  0,-30,  0,  0,-40, 10,-20,-10,-20,-20,-20,  0, 10,-10,-20, 10, 10,  0,-70,-40,  0;
/M: SY='M'; M=-20,-30,-60,-40,-30,  0,-40,-30, 20, 10, 40, 80,-20,-30,-10,-10,-20,-10, 20,-50,-30,-20;
/M: SY='V'; M=  0,-30,-20,-30,-20,-20,-20,-30, 40,-30, 20, 20,-20,-20,-30,-30,-10,  0, 50,-80,-30,-20;
/M: SY='R'; M=-20,-10,-40,-20,-20,-50,-40, 20,-20, 40,-40,-10,  0,  0, 10, 70,-10,-10,-30, 20,-50,  0;
/M: SY='H'; M=-20, 10,-40,  0,  0,-20,-30, 80,-30,-10,-30,-30, 20,-10, 30, 20,-10,-20,-30,-30,  0, 20;
/M: SY='C'; M= -1, -6, 33,-16,-19,-45, -4,-18,-23,-19,-48,-31, -6, -4,-26,-18, 15,  6,-13,-46,-22,-26;
/M: SY='L'; M=-15,-35,-49,-39,-35, 15,-39,-30, 41,-29, 44, 29,-29,-30,-25,-29,-29, -9, 31,-41,-20,-30;
/M: SY='P'; M= 10,-10,-40,-20,-10,-60,-10,-10,-30,-20,-30,-30,-10, 70,  0,  0, 10,  0,-20,-70,-60,-10;
/M: SY='L'; M=-20,-40,-70,-50,-40, 20,-50,-30, 20,-40, 70, 40,-40,-30,-20,-40,-40,-20, 20,-20,-20,-30;
/M: SY='P'; M= 10,-10,-40,-20,-10,-60,-10,-10,-30,-20,-30,-30,-10, 70,  0,  0, 10,  0,-20,-70,-60,-10;
/I:         I=-5; MI=0; MD=-11; IM=0; DM=-11;
/M: SY='E'; M= -2, 32,-66, 41, 42,-70, -2, -1,-29,  5,-44,-31, 23,-15, 25,-15,  0, -5,-25,-82,-50, 33;
/M: SY='T'; M= 10,  5,-14,  0, -5,-40,  5,-15,-11,  0,-31,-15,  5,  5,-10,-10, 20, 29, -5,-44,-30,-10;
/M: SY='I'; M= -7,-30,-27,-30,-27,  2,-27,-30, 55,-23, 20, 20,-20,-27,-30,-23,-17,  0, 43,-65,-23,-27;
/M: SY='L'; M=-15,-35,-58,-42,-35, 13,-42,-29, 27,-32, 52, 32,-32,-27,-21,-33,-31,-11, 23,-32,-21,-28;
/M: SY='K'; M=-11, 11,-61, 11,  7,-58, -7,  0,-21, 36,-41, -4, 17,-16,  8, 20,  4,  0,-26,-46,-40,  3;
/M: SY='S'; M= 10, 10,  0,  0,  0,-40, 10,-10,-20,  0,-40,-20, 10, 10,-10,-10, 20, 20,-10,-30,-30,-10;
/M: SY='A'; M= 27,  0,-31,  0, -1,-41, 13,-21,-11,-18,-22,-21,  0,  8,-11,-21, 11, 12, -1,-70,-41, -1;
/M: SY='K'; M=-13,  9,-69, 11, 14,-63,-15, -8,-21, 31,-33, -3, 11,-18, 14, 13, -3, -4,-24,-55,-48, 11;
/I:         I=-15; MD=-32;
/M: SY='D'; M=  5, 21,-46, 25, 23,-54, 12, -6,-24, -4,-39,-30, 16, -9,  7,-19,  5,  0,-19,-68,-42, 15; D=-15;
/I:         I=-15; MI=-32; IM=-32; DM=-32;
/M: SY='G'; M=  8, 14,-40, 14, 10,-51, 28,-10,-24, -7,-44,-30, 13, -7, -6,-22, 10,  3,-18,-66,-43,  0;
/I:         I=-13; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='L'; M= -9,-18,-39,-23,-19,  0,-24,-15, 10,-16, 24, 19,-16,-11,-10,-17,-16, -8,  9,-26,-18,-15; D=-13;
/I:         I=-13; DM=-27;
/M: SY='M'; M= -7, -9,-38,-10, -4,-17,-19, -8,  4, -5, 10, 17, -7,-13,  2,-10,-11, -6,  6,-40,-25,  0; D=-13;
/I:         I=-13; DM=-27;
/M: SY='E'; M=  4, 17,-55, 23, 25,-65, 24,-11,-30, -8,-45,-35, 12,-11,  8,-26,  4, -4,-23,-81,-54, 16;
/M: SY='S'; M= 10,  5,  1, -3, -4,-41,  7,-13,-19, -6,-38,-22,  5,  7,-13,-13, 18, 17, -9,-39,-30,-12;
/M: SY='C'; M=-16,-39, 63,-46,-48,-46,-29,-35, -6,-53,-37,-31,-36,-29,-52,-35, -2,-17,  4,-85,-13,-48;
/M: SY='A'; M= 30,  0,-30,  0,  0,-40, 10,-20,-10,-20,-20,-20,  0, 10,-10,-20, 10, 10,  0,-70,-40,  0;
/M: SY='P'; M= 10,-10,-40,-20,-10,-60,-10,-10,-30,-20,-30,-30,-10, 70,  0,  0, 10,  0,-20,-70,-60,-10;
/M: SY='W'; M=-70,-60,-90,-80,-90,  0,-80,-30,-60,-40,-20,-50,-50,-70,-60, 20,-30,-60,-80,180,-10,-70;
/M: SY='L'; M=-20,-40,-70,-50,-40, 20,-50,-30, 20,-40, 70, 40,-40,-30,-20,-40,-40,-20, 20,-20,-20,-30;
/M: SY='L'; M=-20,-40,-70,-50,-40, 20,-50,-30, 20,-40, 70, 40,-40,-30,-20,-40,-40,-20, 20,-20,-20,-30;
/I:         I=-5; MI=0; MD=-11; IM=0; DM=-11;
/M: SY='G'; M=  9,  0,-40, -1, -1,-60, 56,-28,-30,-18,-50,-39,  0,-10,-19,-35,  9,  0,-20,-76,-60,-10;
/M: SY='M'; M=-20,-30,-60,-40,-30,  0,-40,-30, 20, 10, 40, 80,-20,-30,-10,-10,-20,-10, 20,-50,-30,-20;
/M: SY='H'; M=-20, 10,-40,  0,  0,-20,-30, 80,-30,-10,-30,-30, 20,-10, 30, 20,-10,-20,-30,-30,  0, 20;
/M: SY='K'; M=-20, -2,-64, -4, -4,-66,-24, -4,-20, 56,-40,  6,  8,-16, 10, 46, -2, -2,-30,-28,-50,  0;
/M: SY='K'; M=-20,  0,-70,  0,  0,-70,-20,-10,-20, 60,-40, 10, 10,-20, 10, 40,  0,  0,-30,-40,-50,  0;
/M: SY='S'; M= 10, 10,  0,  0,  0,-40, 10,-10,-20,  0,-40,-20, 10, 10,-10,-10, 20, 20,-10,-30,-30,-10;
/M: SY='M'; M= -7,-22,-45,-28,-24, -7,-26,-26, 18,-14, 24, 28,-18,-19,-17,-21,-13,  2, 17,-46,-26,-20;
/M: SY='E'; M=  1, 19,-62, 25, 32,-62, 11, -9,-26, -4,-37,-25, 13,-12, 15,-24,  1, -7,-18,-84,-51, 23;
/I:         E1=0; IE=-105; DE=-105;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2015_08 which contains 320'201 sequence entries.


Total number of hits 13 in 13 different sequences
Number of true positive hits 13 in 13 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] CVC
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
13 sequences

HM10_CAEEL  (P41935), VSX1_BOVIN  (Q9GMA3), VSX1_CARAU  (Q90277), 
VSX1_CHICK  (Q9IAL2), VSX1_DANRE  (O42250), VSX1_HUMAN  (Q9NZR4), 
VSX1_MOUSE  (Q91V10), VSX1_XENLA  (Q0P031), VSX2_CHICK  (Q9IAL1), 
VSX2_DANRE  (O42477), VSX2_HUMAN  (P58304), VSX2_MOUSE  (Q61412), 
VSX2_ORYLA  (Q9I9A3)
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