Entry: PS51497

Forthcoming changes to the profile format
General information about the entry

Entry name [info] UMA
Accession [info] PS51497
Entry type [info] MATRIX
Date [info] JUN-2010 (CREATED); OCT-2013 (DATA UPDATE); OCT-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC51497
Associated ProRule [info] PRU00830

Name and characterization of the entry

Description [info] UMA domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=48;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=44;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3741412; R2=0.0063080; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2953.71540; R2=14.69104; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=972; N_SCORE=8.5; H_SCORE=14898; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=655; N_SCORE=6.5; H_SCORE=12562; MODE=1; TEXT='?';
/DEFAULT: M0=-25; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='M'; M=-51,-57,-72,-64,-33,-70,-53, 17,-61, 63, 92,-66,-66,-54,-59,-61,-48, 12,-61,-40;
/M: SY='D'; M=-49,-66, 92, 46,-72,-28, -8,-71,-38,-68,-64,-29,-51, 25,-46, 20,-43,-67,-79,-57;
/M: SY='D'; M=-22,-66, 80,-38,-72, 74,-50,-75,-50,-72,-66,-31,-55,-48,-58,-39,-50,-70,-72,-62;
/M: SY='V'; M=-43,-57,-72,-67,-40,-74,-73, 62,-64,-24,-27,-65,-65,-64,-66,-56,-40, 83,-70,-47;
/M: SY='P'; M=-53,-78,-15, -3,-74,-56,-55,-62,-48,-71,-58,-57,120,-13,-60,-50,-47,-67,-67,-69;
/M: SY='F'; M=-58,-58,-75,-70,108,-71,-58,-10,-66,-14,-35,-65,-72,-74,-64,-60,-51, 29,-34,-12;
/M: SY='K'; M=-28,-60,-43, 36,-57,-60,-47,-21, 62,-34, 51,-42,-51,-11,  8,-42, 37, -1,-65,-51;
/M: SY='I'; M=-52,-60,-72,-67, 11,-74,-63, 66,-65, 51, 28,-66,-66,-61,-65,-61,-33, 23,-59,-40;
/M: SY='N'; M=  7,-56,  3,-47,-61, 28, 50,-39,-46,-60,-52, 55,-56,-42,-51, 55,-36,  3,-73,-52;
/M: SY='P'; M=-18,-70, 27, 57,-70,-57,-49,-60,  6,-64,-57,-47, 86, -8,-16,-46,-46,-15,-68,-62;
/M: SY='R'; M=-28,-65,-46, -7,-62,-19, 47,-62, 56,-47, 34,-39,-55, 26, 63,  1,-47,-59,-64,-48;
/M: SY='F'; M=-33,-59,-70,-66, 85,-69,-50,-13,-63, 40,-30,-65,-23,-64,-61,-59,-52, -4,-36, 53;
/M: SY='K'; M= 27,-10,-45, 23,-60,-29,-47,-54, 48, -2,-47,-43,-54, 33, 22, 15,-22,-24,-63,-53;
/M: SY='P'; M=  7, 52,-49,-47,-62, -3,-52,-56, -6,-35,-52, 14, 61,-18, 10, 20, 36,-28,-69,-59;
/M: SY='P'; M= -3,-64, 23,-41,-58,-54,-50, -9, 23,-54, 16, -4, 76,-12,-29,  8,-13,  1,-65, -3;
/M: SY='P'; M=  2,-63, 24, -6,-62,-25,-46,-37,-41,-36,-53,  4, 60, 37, -1, 45,-21,-39,-66,-13;
/M: SY='K'; M= 17,  8,-46,  2,-31,  9,-49,-31, 42,-31,-51, -8, 20,  4, 31, 16,-11,-54,-64,-54;
/M: SY='V'; M=-41,-58,-13,-31, -5, 23,  8,-18, -7,-23,-10, -9,-59,-23,-52, 33,-16, 51,  1, 13;
/I:         I=-21; MI=0; MD=-53; IM=0; DM=-53;
/M: SY='Y'; M=-63,-77,-37,-29, -2,-70,  0,-69,-58,-45,-62, -2,-74, 31,-26, 17, 24,-68,  5, 44; D=-21;
/I:         I=-21; DM=-53;
/M: SY='Q'; M=-23,-68, 20, 14,-70,  8, 11,-62,-17,-63,-56,-29, 19, 62, -2,  0, 17,-15,-72,-58; D=-21;
/I:         I=-21; DM=-53;
/M: SY='L'; M=-31,-57,-67,-61, 21,-69,-56, 14,-60, 63, 38,-24,-67,  1,-59,-57,-20, 23,-58,-39;
/M: SY='P'; M=-34,-70, 27,  0,-46,-54,-51,-42,-45,-65,-56,  3, 99, 16,-54, -6, 13,-41,-69,-62;
/I:         I=-19; MD=-47;
/M: SY='M'; M=-10,-71,  5,-66,  1,-40,-69, 28,-69,  8, 34,-66,-19,-36,-72,-18,-56, 19,-74,-56; D=-19;
/I:         I=-19; MI=0; MD=-47; IM=0; DM=-47;
/M: SY='G'; M=-30,-67, 17, -5,-61, 41, -1,-54,-50, 17,-49, 16,-63, 37,-10,-24,-53,-15,-71,-58; D=-19;
/I:         I=-19; DM=-47;
/M: SY='F'; M= 21,-63,-67,-63, 32,-62,-59, 29,-60, 23, -1,-60,-67,-58,-26, 17,-13,-37, 27, 18; D=-19;
/I:         I=-19; DM=-47;
/M: SY='T'; M=-19, 16,-19,-43,-29,-57, 46,-12, 17, 10,-41,-41,-24, 31,  9, 15, 49,-24,-68,-47;
/M: SY='I'; M=-35,-60,-66,-60,  4,-69,  2, 48,-12, 44,  4,-60,-65,-30,-24,-28,-47, 25,-53, 36;
/M: SY='K'; M=-49,  5,-42,-39,-57,-52,-44,-60, 58,-63,-53, 47, 55, -9, -2, -3, 26,-58,-61, 22;
/M: SY='D'; M=-44,-61, 59, 15,-64,-51,-44,-62,-12,-40,-56, -5,-11,-36, 45, 44, 34,-57,-73,-55;
/M: SY='P'; M=-22, 41,-59,-25,  1,-43,-55, 12,-54, 44,-32,-30, 47, 30,-57,-22,-15,  1,-62,-47;
/M: SY='S'; M= 28,-57, 20,-16,-55,-18, -1,-37,-45,  9, -1,-12,  6, 16,-18, 49,-20,-30,-66,-23;
/M: SY='Q'; M= -9,-63, 27, 60,-66,-33,-15,-64, -5,-62,-55,-37,-50, 60,-11, 29, 12,-59,-67,-24;
/M: SY='I'; M= -8,-59,-22,-61, 14,-46,-61, 60,-60, 25,-11,-19,-31,-58,-62,-17,-15, 36,-60, -8;
/I:         I=-16; MD=-40;
/M: SY='D'; M=-25,-63, 52, 49,-51,-43,-47,-16,-32, 30,-42,  4,-57,-23,-12,-34,-47,  5,-68,-14; D=-16;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='K'; M=-23,-65,  7,-12,-61,-59,-14,-56, 32,  7,-17, -4,  2,  4, 25, 25,  2,-37,-71,-56; D=-16;
/I:         I=-16; DM=-40;
/M: SY='E'; M= 26,-61, 21, 58,-66,-51,-15,-61,  0,-61,-55, 10,  3,  8, 21, 12,-16,-26,-69,-57;
/M: SY='Y'; M=-27,-63,-56, 21, 33,-66,-41,-37,-32, 32,  5,-60,-34,-49,-53,-24,-37,-12,-37, 85;
/M: SY='Q'; M=-50,  4, 35, 40,-68,-54, 32,-67,  9,-65,-56, 51,-55, 60,-15,-19, -4,-65, 20,-53;
/M: SY='Y'; M=-59,-70,-59,-62, 11,-32, 11,-46,-54,-42,-39,-59,-71,-50,-52,-54,-55,-51,-18,124;
/M: SY='D'; M=-49, -2, 89,-31,-66, -5,-21,-68,-43,-67,-63, 10,-56,-43, -4, 16, 26,-63,-79, -9;
/M: SY='F'; M=-63,  2,-75,-71,109,-71,-54,-38,-66,-31,-40,-65,-74,-74,-64,-62,-56,-17, 31, 37;
/M: SY='Q'; M=  8,-60,  6, -6,-62,-31, 26,-53,-39,-34,-49, -3,-55, 60,  7, 27, 37, -2,-71,-52;
/M: SY='L'; M=-30,-58,-64,-56,-38,-69,  1,-25,-56, 65,-25,-60,-66, 24,-21,-54, 15, 28,-65,-45;
/M: SY='E'; M=-48,-69,-21,103,-71,-31,-43,-68,-31,-64,-60,-46,-45,-24,-41,-46,-49,-27,-69,-62;
/M: SY='R'; M=-42,-69,-45,-15,-64,-29, 41,-68, 25,-40,-52, 30, -8,  0, 86,-46,-51,-64,-68,-51;
/M: SY='S'; M=  7,-17,-47,-22, -3,-31,-48,-58, -2,-45,-52,-16,-54, 44,  5, 63, 34,-52,-66,-51;
/M: SY='V'; M= 34,-55,-66,-60,-46,-61,-65, 17,-59, -1, 30,-60,-63,-58,-62,-29, -5, 69,-70,-51;
/M: SY='L'; M= 24,-59,-65,-54,-10,-63,-56, 10,-57, 60,-27,-62, -9, 37,-57,-52,-49, -3,-61,-45;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_11 which contains 547'085 sequence entries.


Total number of hits 14 in 14 different sequences
Number of true positive hits 14 in 14 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] UMA
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
14 sequences

MB12A_BOVIN (Q3T0N1), MB12A_CHICK (Q5ZJX7), MB12A_DANRE (Q7SXX7), 
MB12A_HUMAN (Q96EY5), MB12A_MOUSE (Q78HU3), MB12A_RAT   (Q6P777), 
MB12A_XENLA (Q7ZYJ7), MB12B_HUMAN (Q9H7P6), MB12B_MOUSE (Q6KAU4), 
UBA1L_HUMAN (F5GYI3), UBAP1_HUMAN (Q9NZ09), UBAP1_MOUSE (Q8BH48), 
UBAP1_RAT   (Q5XIS7), UMAD1_HUMAN (C9J7I0)
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