Entry: PS51511

Forthcoming changes to the profile format
General information about the entry

Entry name [info] FIP_RBD
Accession [info] PS51511
Entry type [info] MATRIX
Date [info] NOV-2010 (CREATED); OCT-2013 (DATA UPDATE); OCT-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC51511
Associated ProRule [info] PRU00844

Name and characterization of the entry

Description [info] FIP-RBD domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=63;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=58;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3604796; R2=0.0055957; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=4780.27394; R2=20.76152; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=1098; N_SCORE=8.5; H_SCORE=23839; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=740; N_SCORE=6.5; H_SCORE=20144; MODE=1; TEXT='?';
/DEFAULT: M0=-15; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='H'; M=-31,-43,-30, -3, 22,-41, 42,  0, 24, -1,-26, 23,-41,  5,-26,  9, 27,  4,-47,-25;
/M: SY='Q'; M=  2,-45,  3, 13,-42, -6,-32,-30,  3,  0, 21,  2, 18, 37,  4, -6,  2,  2,-50,-37;
/M: SY='E'; M=-10,-48,-25, 43,-39, 18,-30,-42,  0, -3,-33,-29, 18, 20, 20, -2,  1,-39,-43, 13;
/M: SY='G'; M= 22,-42,-32, -8,-40, 27, 15, -3,-30, -9,  8, 25,-41,  6, -6, 18,-26,  7,-51,-36;
/M: SY='Q'; M= -8,-46,-30, 11,-40,  5,-30,-35, -3,  0,-30,-27, 12, 56,-10, 37,-25,-10,-45,  4;
/M: SY='P'; M=-33,-48,-36, -6,  2, -5,  1,-13, 15,  8,-28,-32, 47,-27, 28, 13, -4,-34,-40, 21;
/M: SY='D'; M=  1,-44, 46, 17,-39,-37, 15, -1,-27, 12,-29, 34,-42,-25,  2, 12,-26,-10,-56,-35;
/M: SY='Q'; M= 26,-45, -6, -3,-36,-40,-33, 14, -1, 23, 22,-34, 11, 54,-30,-29,-31,-23,-46,-34;
/M: SY='Q'; M= 19,-46, 26, 15,-46,-37,-30, -9,-22,-36, 12, 12, 10, 42, 20, -2,-27,  8,-53,-38;
/M: SY='G'; M= 19,-43,-33, -5,-45, 39,-33,-39,  1,-14, 30,-25,-38, 35, -6, 26, -1,-36,-48,-38;
/M: SY='D'; M= -5,-48, 37, 12,-49,-38, 15, -9, 28,-44,-37,-22, 36, 24,  6, 14,  7,-38,-53,-38;
/M: SY='Y'; M= 11,-46, 27, -1,-29,-38, 17, -4,-29,-23,-29,  4,  9, 36,-32, -4, 12,-11,-38, 49;
/M: SY='D'; M= 26,-46, 32, 30,-45,-35,-29,-40, 12,-43,-37, 13, 28, 27,-27, -4,-27, -9,-48,  7;
/M: SY='S'; M= 17,-43,-28, 12,-45, -2, 46,-44,-26,-16,-34,-23, 11, 16,  2, 54,-22,-39,-52,-35;
/M: SY='W'; M=-32,-45,-38, -3,-26,-41,-37,-24, -4, 42,-20,  8, 20,-31,-36, 26, -2,-28, 80,-27;
/M: SY='T'; M= 43,-39, -1, 22,-42,-34, 27, -2,-30,-34,-31,  9,-37,-28,-36,-18, 43,  7,-55,-37;
/M: SY='H'; M= 32,-42, 30,-25,-40,-30, 48,-15,-27,-41,-34, 18,-40, -4,  2, 33,  7,-34,-51, 12;
/M: SY='E'; M=-31,-51, 43, 76,-52,-41,-26,-50,-18,-25,-42,-23,  4, 19,-27, 15,-28,-46,-54,-42;
/M: SY='L'; M=-14,-46, 24, 31,-29,-48, 14, 26, -4, 42,-17,-34,-43,-28,-35,-10,-31,-19,-49,-31;
/M: SY='M'; M=  0,-45, 31, 18,-32,-41,-27, -1,-27, 17, 39, 23,-42, 20,  2,-29, -3,-27,-46, 13;
/M: SY='D'; M= -6,-45, 26,  4, -5, 17,-33, 14,-30,  3, 20,  4,-41, 19, -6, -5, 14,-27,-49,-33;
/M: SY='M'; M= 41, 22,-39, -7, -5,-10,-34,-28,  2,-26, 65,-33,-41, 14,  3, -2,-28, -3,-46,-32;
/M: SY='S'; M=-25, 30, 15,-32,-35,-34,-34, -1,-33, 14,-27, 27,-42,-30,-38, 51, 25, -2,-56,-36;
/M: SY='K'; M= -6,-44,-34,  3,-37,-44,-34,  1, 41, 12,-24,-30,-40, 29, 17, -6, 16, 10,-48,-34;
/M: SY='D'; M= -4,-45, 55, 35,-43,-39, 25,-38,-26, 10,-32, 14,-38, 14,-32, -4, 18,-37,-58,-36;
/M: SY='Q'; M=-31,-50, 31, 55,-55,-39,-24,-51, 30,-48,-40, 12,-34, 60,-17,  2, -3,-47,-52,-39;
/M: SY='L'; M=-35,-43,-47,-37,-22,-53,-36, -9,-32, 57, 20,-43,-50, 32, 18,-39, -6, 20,-46,-28;
/M: SY='Q'; M=-33,-48,-32, 30, -6,-49,-32, 28, 20,  2, 35,-34,-41, 50,  7,-33,-31,  9,-45,-30;
/M: SY='E'; M=-30,-47, 20, 49,-46,-39,-27,-14,  8,-15,-35, 17,-36, 20, 23, 25,  3,-38,-53,-38;
/M: SY='A'; M= 48,-41, 27, 44,-46,-34,-33,-38, -4,-17, 19,-28,-36,-22, -6,-21,  5,-32,-51,-40;
/M: SY='L'; M=-38,-42,-13,-46, 18,-57,-43, 27,-48, 65, -5,-50,-53,-44,-47,-46,-33, 16,-42,-23;
/M: SY='Q'; M=-29,-49,-24, 14,-52,-37,-24,-50, 49,-47,-36, 12,-37, 66, 32, 27,-26,-46,-48,-36;
/M: SY='K'; M=-34,-51, 20, 48,-44,-44, 17,-44, 50,-43,-36,-24,-36, 29, 24,-29,-32,-12,-45, 12;
/M: SY='Q'; M=-32,-51,-27, 18,-50,-43,-25,-38, 45,-38, 18,-25,-38, 80, 28,-27,-32, -4,-46,-34;
/M: SY='E'; M=-15,-51, 41, 67,-55,-42,-26,-54, 45,-49,-42,-21,-32, 29,-15,-27,-31,-48,-52,-41;
/M: SY='E'; M=-32,-50, 14, 68,  5, -1,-28,-15,-20,-15,-35,-28,-36, 16,  7, -1,-32,-39,-43,  7;
/M: SY='D'; M=-11, 18, 39, 34,-42,-44, 21, -6,  2,-11, 12,-26,-39, 16,  4,-28,  8,  7,-55,-35;
/M: SY='N'; M=-12,-40,-19,-32,-40,-30,-24, -1,  3,-35, 20, 89,-45,-26,-30,-22,-21, 22,-61,-39;
/M: SY='R'; M= 10,-47, -4, 21, -3,-41,-29,-38, 32,-19,-32,-27,-40, 44, 44, -7,-30, -5,-46,-33;
/M: SY='R'; M=-17,-52, 27, 46,  3,-44,-25,-50,  7,-44,-38,-25,-39, 44, 62,-29,-34,-46,-47,-33;
/M: SY='L'; M=-38,-41,-56,-48,-14,-56,-38, -4,-48, 74, 56,-53,-54,-40,-45,-48,-34,-12,-43,-25;
/M: SY='R'; M=-35,-54,-21, 51,-53,-46,-24,-53, 17,-47,-37,-26,-38, 54, 72,-29,-35,-48,-48,-37;
/M: SY='Q'; M=  6, 18, 39, 11,-48, 10, 31,-38, -3,-41,-35,-22,-39, 41,-29,  0, 11,  6,-56,-37;
/M: SY='Y'; M=-43,-53,-43,-46, 32,-50,-10,-28,-38,-24,-22,-44,-55,-34,-35,-38,-37,-33,  0,116;
/M: SY='I'; M= -2,-44,-55,-50,-21,-54,-48, 68,-47, 28, 45,-48,-47,-43,-49,-41,-30, 26,-47,-28;
/M: SY='D'; M=-38,-50, 96, 10,-57,-34,-23,-56,-25,-56,-52, 48,-39,-24,-33,-25,-27,-54,-73,-43;
/M: SY='S'; M=-26,-41,  2,-28,-44,  6,-29,-42,  1,-16,-35, 33,-39,-23, 39, 40, 39,-37,-54,-38;
/M: SY='I'; M=-37,-44,-57,-52,-16,-60,-48, 63,-50, 56, -4,-52,-51,-45,-50,-47,-32, 14,-45,-27;
/M: SY='L'; M=-38,-43,-57,-50,-14,-59,-43, 41,-50, 71, -1,-54,-54,-43,-48,-48,-34, -6,-43,-26;
/M: SY='M'; M=  1,-40,-44,-35,-27,-43,-36,-12,-36, 38, 50,-37,-45, 36,-36, 16, -1, 26,-48,-30;
/M: SY='R'; M=-10,-46,-30,-25,-44,-41,-28, -9, 23,-37,-30, 37,-43, 36, 58,-26,  3, 16,-51,-36;
/M: SY='I'; M=-31,-44,-57,-53,-23,-60,-58, 73,-49, -7,-10,-49,-48,-48,-52,-42,-27, 61,-51,-31;
/M: SY='M'; M= -1, 33,-54,-47,-23,-50,-39, 34,-43, 22, 88,-45,-47,-39,-44,-40,-30, 30,-49,-28;
/M: SY='E'; M=-33,-53, 35, 93,-56,-46,-25,-57,-14,-49,-46,-25,-28, -8,-24,-28,-32,-49,-54,-45;
/M: SY='H'; M=-36, 28,-22, 24,-46,-41, 87,-52, 25,-45,-34, 28,-40, 16, 33,-27, -2,-48,-59,-27;
/M: SY='H'; M= -5, 38, 21,-26,-35,-35, 54,-40,  1,-41,-34, 47,-42, 12,-29,  0, 22,-18,-48, 34;
/M: SY='P'; M=-38,-64,-39,-27,-58,-40,-42,-46,-35,-56,-42,-45,117,-38,-47,-35,-31,-51,-51,-55;
/M: SY='Q'; M=  8,-43, 15, 27,-50,-33,-27,-45,-19,-45,-37, 14,-36, 56,  5, 34, 29,-39,-53,-38;
/M: SY='I'; M=-38,-45,-57,-52,-16,-60,-47, 62,-50, 60, -3,-52,-51,-45,-50,-48,-33, -1,-44,-26;
/M: SY='L'; M=-39,-41,-56,-48,-12,-58,-40, -4,-50, 79,  0,-56,-56,-42,-47,-49,-35,-11,-43,-25;
/M: SY='E'; M= -6,-52, -9, 84,-55,-44,-25,-53,-12,-47,-40,-28,-30, 48, 10,-26,-32,-47,-50,-42;
/M: SY='I'; M= -5,-43,-42,-41,-29,-46,-44, 59,-39,-16,-16, 21,-45, 16,-42, -1,-25, 47,-52,-33;
/M: SY='P'; M=-11,-48,-36,-26,-44,-14,-37, -1, 53,-36, 20,-30, 58,-25,  8,-29, 11,  0,-48,-39;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_11 which contains 547'085 sequence entries.


Total number of hits 17 in 17 different sequences
Number of true positive hits 17 in 17 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info]
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] FIP-RBD
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
17 sequences

RB6I2_HUMAN (Q8IUD2), RB6I2_MOUSE (Q99MI1), RFIP1_HUMAN (Q6WKZ4), 
RFIP1_MOUSE (Q9D620), RFIP1_RAT   (Q3B7T9), RFIP2_HUMAN (Q7L804), 
RFIP2_MOUSE (G3XA57), RFIP3_DANRE (Q7T005), RFIP3_HUMAN (O75154), 
RFIP3_MOUSE (Q8CHD8), RFIP4_HUMAN (Q86YS3), RFIP4_MOUSE (Q8BQP8), 
RFIP4_XENTR (A4IIE8), RFIP5_HUMAN (Q9BXF6), RFIP5_MOUSE (Q8R361), 
RFP4A_DANRE (Q3LGD4), RFP4B_DANRE (B3DGU2)
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