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Entry: PS51522

General information about the entry

Entry name [info] ZF_NANOS
Accession [info] PS51522
Entry type [info] MATRIX
Date [info] 01-FEB-2011 CREATED; 10-MAY-2017 DATA UPDATE; 27-SEP-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC51522
Associated ProRule [info] PRU00855

Name and characterization of the entry

Description [info] Zinc finger nanos-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=55;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=50;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.4555142; R2=0.0061741; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=8011.4443359; R2=2.1657834; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=818; H_SCORE=9783; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=494; H_SCORE=9081; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-49; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='C'; M= -76,  77, -84, -81,  11,  23,  57,  -8,  41, -79, -76, -74, -90, -78, -75,   4,   6,  24, -92,  15;
/M: SY='C'; M= -79, 157, -99, -99, -89, -94, -99, -96, -94, -86, -87, -85,-109,-102,-101, -81, -79, -83,-119,-100;
/M: SY='W'; M= -12,  50, -77,   2, -78,  27, -78, -81,  -6, -85, -81,  43, -89, -75,   6,   7,  -2,  13,  73,  43;
/M: SY='Y'; M= -90, -94, -96, -93,  92, -99, -71,   4, -82, -18, -66, -90,-100, -87,  26, -87, -83, -71, -58,  93;
/M: SY='C'; M= -79, 154, -99, -99, -87, -95, -99,   1, -95, -83, -83, -85,-108,-102,-101, -82, -79, -78,-116, -97;
/M: SY='Y'; M=  -6, -95, -83,  22,  24, -93, -72, -77,   3,   9,  34, -83, -92, -70,  62, -81, -81, -79,  54,  71;
/M: SY='H'; M= -73, -91,  19,   7, -87,  29,  57, -95,  38, -93, -84,  35, -84, -67, -70,  45,   6, -91, -94,  26;
/M: SY='N'; M=  -9, -88, -72, -73, -81, -81, -73, -80,  57, -86, -79,  64,  18, -70, -67,  -3,  42,   4, -90,  43;
/M: SY='G'; M=   3,  29, -75,   9, -89,  65, -76, -97,  29, -93, -84,   7, -86,  41,  -1, -69, -79, -92, -87,  32;
/M: SY='E'; M= -78,  46, -71,  68,  15, -92, -76, -76, -74,  35, -70, -80, -86,  16, -79,  11,  15, -76, -86,  33;
/M: SY='Q'; M=  -2, -93, -70,  51, -92, -83, -74, -84, -69, -16,  45,  18,  55,  62, -75,  24,  -1, -83, -96, -85;
/M: SY='R'; M=  26, -91, -78,  -2,  21,  -3, -75, -87,  10, -83,  44,  18,   6,  13,  63,   0, -75, -84, -90, -77;
/I:         I=-12; MD=-30;
/M: SY='E'; M=  22,  48,  29,  67,-108, -93, -88,-106, -80,-103, -99, -82,  18, -75, -89,   6, -83, -98,-111,-101; D=-12;
/I:         I=-12; MD=-30;
/M: SY='I'; M= -11,-106, -96,  21,   4,-109, -99,  43, -84, -82, -82, -96,-102, -88,  42, -92,  -4,  14,-106, -89; D=-12;
/I:         I=-12; MD=-30;
/M: SY='W'; M=  -1,-100,-100, -94,   6, -98, -83, -71,   6,  -4, -74, -97,-102, -88, -87, -89, -87,  29, 100,  85; D=-12;
/I:         I=-12; MD=-30;
/M: SY='Q'; M=  10, -96, -80,  13, -96, -85,  47, -92, -73, -24,  28, -76, -90,  66,  10,  53, -76, -89,-102, -84; D=-12;
/I:         I=-12; MI=0; MD=-30; IM=0; DM=-30;
/M: SY='S'; M= -66, -84,  13, -74, -92,  22,  27, -90, -75, -93, -86,  16, -82, -71, -81,  81,  57, -84,-103, -83;
/M: SY='H'; M= -87, -99,  21, -68, -87, -88, 149,-104, -75, -87, -73, -59, -87, -65, -70, -76, -84,-103,-121, -56;
/M: SY='C'; M= -73,  73,   9, -78, -89,  -6,  47, -80, -78, -86, -81,  51,  18, -77, -84,  41,  35,  20,-108, -84;
/M: SY='C'; M= -82,  88,-100, -94,  16,-101, -89,  52, -87,  45,  45, -91, -98, -88,  15, -88, -79,  -7, -92, -73;
/M: SY='K'; M= -80, -95, -77, -66,   2, -88, -72, -93,  82, -90, -81, -70, -86, -60,  75,  11, -76, -90, -85,  22;
/M: SY='D'; M= -16, -94,  74,   1, -94,  -6, -75, -98,  59, -97, -90,  42, -84, -67, -66,  -4, -74, -95,  70, -82;
/I:         I=-20; MD=-50;
/M: SY='P'; M=  10, -98,  29,  25,-102,  13, -81,-100,  37, -99, -91, -74,  42, -70,  40,   3, -79, -95,-100, -92; D=-20;
/I:         I=-20; MI=0; MD=-50; IM=0; DM=-50;
/M: SY='D'; M= -88,-102,  70,  26,-105, -91, -78,-105,  35,-104, -97,  35, -91, -71,  36, -78,   5,-101,-112, -93; D=-20;
/I:         I=-20; DM=-50;
/M: SY='G'; M= -70, -98, -86, -97,-104, 103, -92,-112, -91,-107, -96, -71, -89, -88, -98, -70, -89,-105, -95, -99; D=-20;
/I:         I=-20; DM=-50;
/M: SY='D'; M= -81, -96,  44,   3,   2,  -4, -82, -85,  25, -10, -83, -74,   9, -74,  36,   9,   6,  -3, -99, -83; D=-20;
/I:         I=-20; DM=-50;
/M: SY='V'; M= -75, -88,-100, -96, -75,-103,-102,   9, -93,   6, -63, -94, -97, -95, -96, -83,  36,  87,-106, -82; D=-20;
/I:         I=-20; DM=-50;
/M: SY='W'; M=  -5, -90, -91, -90, -79, -93, -97,  43, -87, -74, -74, -82, -88, -88, -92,  -6,  78,  25,  85, -78; D=-20;
/I:         I=-20; DM=-50;
/M: SY='C'; M= -79, 157, -99, -99, -89, -94, -99, -96, -94, -86, -87, -85,-109,-102,-101, -81, -79, -83,-119,-100;
/M: SY='P'; M= -83,-107,  19,  23,-103, -86, -84, -93, -77,-101, -89, -84, 122, -78, -89, -80, -77, -97, -98, -99;
/M: SY='H'; M= -79, -91, -87, -81, -75, -97,  80,  50,  49,  12, -62, -80, -90, -77, -73, -83, -76,  51, -98, -72;
/M: SY='L'; M= -84, -87,-102, -94, -59,-102, -84, -50, -94,  91,  57,-100,-100, -87, -91, -94, -80, -57, -89, -70;
/M: SY='W'; M=  -6, -94, -82, -71,  43, -85, -77, -89,  40, -85, -80, -74, -89,  40,  70,  32, -76, -87,  73, -68;
/M: SY='R'; M=  16, -90, -72,   4,  20, -80, -73, -91,  40, -89, -82,  41, -86,  14,  60,  38, -71, -86, -91, -78;
/M: SY='Y'; M= -82,  38, -85, -81, -60, -93,  62,  20, -79,  -3,  46, -80, -93,  53, -78, -78,  15, -71, -72,  92;
/M: SY='V'; M=   2, -86, -85, -77, -81, -90, -86,  -4,  43, -70,  34, -78, -87,  20,   0, -72,  47,  62, -98, -80;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='C'; M= -79, 157, -99, -99, -89, -94, -99, -96, -94, -86, -87, -85,-109,-102,-101, -81, -79, -83,-119,-100;
/M: SY='P'; M= -79,-101,  51,   4,-101,  36, -78, -99,  12, -99, -89, -71,  78,  21,  39, -74, -79, -97, -97, -90;
/M: SY='H'; M= -81,  38, -92, -89,  12, -99,  77,  58, -83,  -8, -62, -84, -95, -83,  15, -85, -77,  49, -92,  16;
/M: SY='C'; M= -79, 157, -99, -99, -89, -94, -99, -96, -94, -86, -87, -85,-109,-102,-101, -81, -79, -83,-119,-100;
/I:         I=-26; MD=-65;
/M: SY='G'; M= -73, -97, -77,  22,-102,  81,  27,-106,  24,-102, -91, -70, -86,  12, -79,   0, -83,-101, -96, -91; D=-26;
/I:         I=-26; MI=-65; MD=-65; IM=-65; DM=-65;
/M: SY='A'; M=  95, -82, -84, -80, -96, -69, -87, -86, -81, -89, -82,   9, -87, -78, -86,   3, -71, -74, -97, -91; D=-26;
/I:         I=-26; DM=-65;
/M: SY='T'; M= -73, -84, -78, -79, -89, -88, -85, -82, -71, -86, -81, -68, -82, -77,  36,  -1, 107, -74,-106, -85; D=-26;
/I:         I=-26; DM=-65;
/M: SY='G'; M=   2, -93, -82, -92,-100, 103, -88,-106, -87,-102, -91, -68, -86, -84, -94, -66, -84, -98, -91, -95;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='D'; M=   0, -94,  73,  58,  16, -86,  27, -94,  44, -90, -87, -65, -81, -65, -68, -72,   5, -89, -98, -79;
/M: SY='Q'; M= -82, -93,  54, -65,  14, -86, -70, -80,  44,   8,  45,  46, -88,  60, -67, -75, -76, -83, -89,  14;
/M: SY='A'; M=  83, -82, -79, -79, -94,  33, -83, -88, -79, -90, -83,  25, -84, -75, -84,  31, -69, -77, -95, -89;
/M: SY='H'; M= -87, -99, -71, -71, -85, -89, 153,-104, -76, -86, -71, -60, -87, -65, -70, -76, -85,-103,-121, -54;
/M: SY='T'; M= -71, -81, -76, -78, -84, -87,  57, -74, -76, -79, -75, -65, -79, -78, -82, -56, 112,  -3,-107, -79;
/M: SY='E'; M= -80, -94,  18,  50, -79, -93, -80,  49,  -6, -14, -72, -77,  36, -72,  -2, -75,  42, -68, -91,  26;
/M: SY='K'; M=  21, -87, -78, -70, -87, -82, -79, -83,  72,   3, -76, -70, -83, -66,  28,  32,  40, -79, -94, -82;
/M: SY='Y'; M= -86, -99, -81,   8, -48, -95,  67,  19,   0, -72, -68, -82, -94, -73, -75, -82, -82, -76, -58, 119;
/M: SY='C'; M= -80, 149, -93, -93, -88, -93,  73, -97, -91, -86, -84, -80,-105, -94, -94, -81, -80, -86,-119, -89;
/M: SY='P'; M= -84,-105,  41, -70, -98, -86, -84, -87, -80,  -7, -84, -83, 120, -82, -91, -81, -77, -92, -99, -96;
/M: SY='M'; M= -81, -93, -80,  14, -76, -92, -73,   4,  50,  13,  85,   6, -88,  16,  38, -80, -77, -72, -88,  15;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_09 which contains 555'594 sequence entries.


Total number of hits 11 in 11 different sequences
Number of true positive hits 11 in 11 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Feature key [info] ZN_FING
Feature description [info] Nanos-type
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
11 sequences

NANO1_DANRE (E7FDB3    ), NANO1_HUMAN (Q8WY41    ), NANO1_MOUSE (Q80WY3    ), 
NANO1_XENBO (Q90ZZ5    ), NANO1_XENLA (Q07937    ), NANO1_XENTR (Q90ZZ6    ), 
NANO2_HUMAN (P60321    ), NANO2_MOUSE (P60322    ), NANO3_HUMAN (P60323    ), 
NANO3_MOUSE (P60324    ), NANOS_DROME (P25724    )
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PDB
[Detailed view]
2 PDB

5KL1; 5KL8

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