Entry: PS51528

Forthcoming changes to the profile format
General information about the entry

Entry name [info] FLAVIVIRUS_NS3PRO
Accession [info] PS51528
Entry type [info] MATRIX
Date [info] MAR-2011 (CREATED); OCT-2013 (DATA UPDATE); SEP-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC51527
Associated ProRule [info] PRU00860

Name and characterization of the entry

Description [info] Flavivirus NS3 protease (NS3pro) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=180;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=175;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3189375; R2=0.0084890; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=30450.60938; R2=46.76078; TEXT='HScore';
/CUT_OFF: LEVEL=0; SCORE=1023; N_SCORE=11.0; H_SCORE=58975; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=493; N_SCORE=6.5; H_SCORE=53504; MODE=1; TEXT='?';
/DEFAULT: M0=-42; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='S'; M=  32, -65, -55, -59, -76,  19, -59, -74, -58, -77, -69,  43, -66, -52, -63,  85, -43, -66, -82, -69;
/M: SY='D'; M= -60, -76,  75, -47, -83,  53, -56, -84,  37, -84, -75,  56, -68, -54, -55, -51, -58, -81, -86, -72;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='V'; M=   8, -69, -75, -74, -58,  29, -76,  42, -72,  12, -46, -67, -74, -69, -75,  12, -54,  59, -79, -63;
/M: SY='F'; M= -69, -71, -82, -74,  72, -83, -64, -41, -66,  62,  50, -76, -82, -68,  29, -73, -64, -47, -60, -40;
/M: SY='W'; M= -64, -81, -84, -76,  37, -73, -82,  58, -71, -52, -55, -74, -75, -69, -75,  37, -63, -49, 139, -38;
/M: SY='D'; M= -60, -77,  69,  18, -76,  39, -62, -72, -59,  -5, -67, -50,  53, -58, -68, -54,  33, -71, -84, -71;
/M: SY='M'; M= -57, -71, -75, -71, -59,  17, -71,  17, -69,   4,  71, -67,  43, -68, -73, -61,  28,  50, -79, -62;
/M: SY='P'; M=  15, -83, -66, -56, -82, -66, -68, -72, -57, -79, -67, -67, 112, -62,  18, -57,  19, -71, -79, -78;
/M: SY='E'; M= -54, -73,  25,  82, -76, -68, -59, -65, -50, -69, -67, -52, -61, -44, -58,  44,  21,  18, -84, -69;
/M: SY='P'; M=  14, -76, -75, -68,  26, -73, -65,  15, -69,  21, -49, -74,  76, -69, -73, -64, -59,  11, -62,  51;
/M: SY='P'; M=   5, -80, -52,  62, -76, -70, -61, -71,  25,  -4, -63, -62,  77, -48,  21, -59, -59, -69, -77, -71;
/M: SY='E'; M= -60, -81, -45,  78, -83, -71, -58, -76, -48, -76, -68, -58,  77,  49, -57, -54,  29, -73, -80, -73;
/M: SY='C'; M=   7,  63, -64,  29, -63, -72, -68, -47, -58,   9, -53, -63, -72, -59,  20,  13,  20,  47, -83, -66;
/M: SY='H'; M=  19, -72,  22,  27, -63,   6,  73, -68, -58, -64,  47, -51, -66, -52, -61,  23,  20, -65, -75,  36;
/M: SY='Q'; M= -61, -77,  63, -42, -79, -68, -58, -66,  45, -71, -64, -48,  30,  69, -48, -53,  30,   8, -83, -67;
/M: SY='P'; M=  30, -72, -67, -64, -68,  39,  48, -62, -65,  11,  47, -59,  53, -60, -69,  24, -57, -62, -78, -64;
/M: SY='P'; M= -60, -78,  32,  41,  34,   9, -63, -68, -60,  -2, -63, -58,  71, -57, -67,  27, -57, -69, -73, -61;
/I:         I=-22; MD=-57;
/M: SY='N'; M= -71, -86, -63,  37,  22,  16, -73, -88, -70, -86, -82,  41, -81, -68, -77,  11,  18, -84, -90, -75; D=-22;
/I:         I=-22; MI=0; MD=-57; IM=0; DM=-57;
/M: SY='H'; M= -83,-101,  32,  14,-100,   5,  63,-106,  35, -99, -89, -67, -86, -68, -68, -77, -83,-102,-106, -82; D=-22;
/I:         I=-22; DM=-57;
/M: SY='L'; M= -61, -70, -75, -68, -51, -80, -70, -37,  14,  64, -39, -71,  27, -66, -66, -65,  28,  36, -76, -59;
/M: SY='P'; M= -62, -79, -51,  42, -80, -68, -60, -75,  54, -78, -68,  27,  83, -49, -50, -54,  28, -73, -80, -73;
/M: SY='D'; M=   5, -74,  96,  19, -82, -62, -54, -78, -53, -79, -75,  40, -65, -53, -62, -50,  29, -73, -95, -70;
/M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='V'; M=   4, -67, -78, -74,  48, -78, -78,  19, -72, -43, -46, -71, -75, -75, -74, -60,  34,  76, -74, -51;
/M: SY='Y'; M= -71, -82, -70, -74, -19, -78, -37, -56, -65, -53, -50, -72, -83, -61, -62, -66, -65, -62, -27, 135;
/M: SY='R'; M= -61, -79, -62, -52, -76, -71, -53, -81, -28, -75, -65, -54, -73, -41, 109,  35, -59, -74, -77, -63;
/M: SY='I'; M= -63, -76, -86, -83, -49, -90, -86, 103, -79, -33, -36, -76, -74, -76, -82, -73, -57,  30, -75, -57;
/M: SY='M'; M= -58, -71, -74, -69,  26, -74, -63,  47,  11, -43,  80, -65, -72, -62, -63,  35, -54,  25, -65,  37;
/M: SY='Q'; M=  55, -70, -68, -56, -70, -65, -64, -49, -50, -59, -55, -62, -71,  60,  47, -52, -55,  52, -78, -65;
/M: SY='R'; M=  27, -74, -61, -52, -76, -65, -59, -74,  42, -74, -64, -55,  29, -47,  76,  14,  20, -67, -77, -67;
/M: SY='G'; M=   9, -71, -62, -69, -80,  85, -67, -83, -65, -82, -72, -49, -67, -61, -71,  53, -56, -75, -76, -74;
/M: SY='W'; M= -65, -74, -87, -80,  37, -85, -79,  59, -77,  45, -38, -80, -80, -75, -78, -74, -61,  37,  78, -46;
/M: SY='C'; M= -68,  78, -85, -79,  75, -82, -68, -43, -76,  54,  59, -77, -84, -76, -75, -73, -64, -48, -62, -41;
/M: SY='W'; M= -57, -81, -67,  25, -63,  73, -71, -73, -65, -68,  61, -62, -69, -61, -71, -59, -70, -76, 121, -54;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='T'; M= -61, -74, -56, -53, -66, -68, -55, -71,  54, -72, -63,  39,  30, -49,  48, -51,  58, -67, -72,  33;
/M: SY='Y'; M= -56, -76, -60, -53, -52, -64, -48, -70,  16, -68, -60, -54, -70,  61,  32,  61, -52, -68, -56,  81;
/M: SY='Q'; M= -60, -84, -54, -36, -86, -68,  65, -77, -42, -70, -57, -49, -67, 125, -41, -50, -63, -78, -75, -57;
/M: SY='I'; M=  36, -72, -74, -67, -60, -74, -74,  65,  15, -47, -47, -67, -72, -62,  30, -60, -56,  44, -77, -62;
/M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='V'; M=  38, -68, -80, -74, -56, -75, -82,  59, -73, -42, -43, -74, -74, -72, -76, -61, -53,  74, -81, -62;
/M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='Y'; M= -60, -73, -78, -76, -36, -82, -60,  19, -71, -44, -44, -76, -80, -70, -71, -67, -57,  76, -53,  95;
/M: SY='M'; M=  43, -71, -75, -71, -55,  34, -66, -49, -67, -52,  80, -67, -72, -64, -70, -57, -60,  31,  76,  34;
/M: SY='K'; M= -65, -77, -58, -48, -60, -72,  73, -70,  90,  -3, -57, -51, -68, -45, -34, -60, -60, -70, -67,  46;
/M: SY='N'; M= -60, -74,  59,  17, -82, -58, -48, -79, -47, -80, -70,  85, -68,  66, -54,  16, -52, -78, -89, -69;
/M: SY='G'; M= -53, -75, -55, -67, -81,  88, -62, -86,  15, -85, -73,  60, -69, -60, -64, -49, -62, -82, -77, -75;
/M: SY='V'; M= -52, -64, -72, -70, -58, -78, -79, -29, -68, -46, -48, -65, -71, -71, -72, -53,  71,  85, -88, -63;
/M: SY='F'; M= -74, -71, -87, -82, 115, -83, -68, -45, -79,  24, -46, -78, -86, -86, -76, -75, -67, -51, -44, -23;
/M: SY='H'; M= -65, -75, -51, -55, -69, -67, 133, -79, -56, -69, -57,  43, -68, -50, -55, -52,  41, -76, -99, -44;
/M: SY='T'; M=   8, -61, -58, -60, -68, -66, -68, -59, -58, -64, -60, -48, -60, -62, -66, -36, 111, -51, -87, -66;
/M: SY='M'; M= -61, -71, -74, -63, -52, -74, -58, -41, -63,  53, 104, -67, -74,  56, -62,  10, -58, -47, -73, -54;
/M: SY='W'; M= -73, -92, -93, -78, -37, -75, -76, -64, -70, -60,  57, -87, -79, -68, -72, -78, -79, -75, 164,  62;
/M: SY='H'; M= -69, -81, -53, -53, -68, -71, 149, -86, -58, -68, -54, -43, -70, -47, -52, -59, -68, -86,-103, -37;
/M: SY='V'; M= -54,  54, -79, -75, -56, -82, -83,  21, -73, -43, -45, -72, -77, -76, -76, -61,  29,  88, -88, -63;
/M: SY='T'; M= -52, -61, -57, -61, -67, -68, -68, -58, -57, -63, -60, -47, -59, -62, -66, -35, 115, -50, -88, -65;
/M: SY='R'; M= -62,  77, -65, -58, -69, -72,  50, -73, -40,  -2, -59, -56, -76, -49,  88,  27, -59, -69, -82, -61;
/M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='S'; M=  49, -69, -57,  26, -77,  23, -61, -75, -50, -75, -67, -53, -66, -50,  43,  56, -51, -66, -78, -69;
/M: SY='S'; M=  36, -69,  45, -56, -69, -61, -66, -53, -63,  -1, -58, -56,  40, -60, -68,  48, -50,  33, -83, -67;
/M: SY='L'; M= -65, -70, -85, -78, -43, -87, -73,  47, -78,  77, -31, -82, -81, -72, -77, -75, -61,  16, -73, -55;
/M: SY='W'; M= -57, -71, -65, -65, -59, -65, -62, -54, -56, -56,  79,  38, -70, -57,  20,  39,  34,  10, 102, -53;
/M: SY='W'; M= -64, -82, -82, -74, -48, -74,  45,  39, -70,   1, -53, -74, -76, -67, -72,  20, -65,  10, 142, -41;
/M: SY='N'; M= -61, -76,  25, -48, -80,  17, -51, -80,  39, -79, -68,  71, -70,  49,  52, -52, -57, -78, -81, -68;
/M: SY='G'; M= -50, -77, -63, -70, -82,  98, -69, -89,  22, -85, -74, -50, -67, -63, -66, -50, -67, -83, -73, -76;
/M: SY='R'; M= -62, -80, -56,  19, -78,  16, -56, -82,  67, -77, -67, -52, -68, -42,  83, -58, -62, -77, -75, -66;
/M: SY='R'; M= -59, -72, -61, -58, -63, -68, -58, -56,  25,  29, -53,  42, -73, -51,  62,  35, -54,   8, -79, -62;
/M: SY='V'; M=   5, -70, -80, -75,  27, -78, -65,  17, -72,  12,  49, -75, -78, -70, -72, -66, -57,  60, -61,  60;
/M: SY='S'; M= -52, -70, -52,  15, -76,   9, -57, -73, -48, -74, -66,  30, -65,  34,  34,  58,  51, -67, -82, -67;
/M: SY='P'; M= -66, -82, -72, -61, -66, -73, -68, -55, -67,  36,  47, -75, 109, -67, -74, -67, -60, -61, -76, -70;
/M: SY='H'; M=   7, -71, -58,  15, -59, -64,  91, -58, -59, -62, -57, -53, -69, -52, -60,  55, -52,  30, -74,  46;
/M: SY='W'; M= -61, -85, -68,  37, -53, -66, -77, -75, -61, -73, -73, -70, -70, -57, -67,  51, -64, -80, 155, -40;
/M: SY='G'; M=  58, -71, -58,  38, -80,  71, -67, -79, -61, -77, -69, -55, -65, -57, -68, -47, -60, -68, -75, -75;
/M: SY='S'; M= -53, -69,  71, -47, -79, -54, -52, -78, -54, -81, -74,  70, -67, -50, -60,  73, -44, -74, -92, -69;
/M: SY='V'; M=  16, -66, -81, -75, -56, -78, -83,  22, -73, -41, -43, -76, -77, -75, -76, -63, -51,  93, -85, -62;
/M: SY='R'; M= -63, -76, -66, -56, -55, -77, -57, -53,  60,   9, -52, -61, -74, -50,  64, -63, -60,  30, -65,  51;
/M: SY='R'; M= -59, -77,  50,  48, -80, -67, -55, -81,  41, -78, -70, -48, -65, -42,  61,  36, -55, -75, -81, -67;
/M: SY='D'; M= -68, -81, 119, -31, -88, -64, -53, -86, -55, -85, -84, -35, -67, -54, -63, -56, -57, -83,-103, -70;
/M: SY='M'; M= -63, -72, -79, -72, -42, -82, -60, -36, -63,  51,  63, -75, -80, -63,  28, -70, -60,  41, -63,  60;
/M: SY='I'; M=  50, -70, -79, -74, -57, -72, -80,  78, -73, -42, -43, -72, -72, -70, -76, -60, -55,  44, -77, -62;
/M: SY='C'; M=   9,  97, -62, -62, -74, -55, -65, -74, -62, -74, -69, -51, -70, -56, -67,  90, -42, -64, -86, -70;
/M: SY='Y'; M= -71, -82, -70, -74, -19, -78, -37, -56, -65, -53, -50, -72, -83, -61, -62, -66, -65, -62, -27, 135;
/M: SY='G'; M= -54, -75, -64, -75,  47,  91, -67, -79, -69, -74, -70,  28, -71, -68, -75, -52, -66, -77, -67, -60;
/M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='P'; M= -57, -81, -63, -55, -82,   6, -66, -76,  14, -82, -70, -60, 105, -59, -64,  48, -53, -76, -79, -77;
/M: SY='W'; M= -76,-101,-103, -80, -40, -74,-103, -73, -72, -71, -74, -96, -79, -72, -76, -82, -88, -88, 179, -27;
/M: SY='R'; M=   6, -74, -55, -49, -78, -62, -53, -77,  42, -76, -65,  43, -69,  45,  67,  36, -53, -72, -78, -65;
/M: SY='F'; M= -69, -71, -86, -79,  70, -86, -70,  30, -78,  70, -34, -81, -83, -76, -76, -76, -64, -39, -60, -41;
/M: SY='D'; M=  18, -77,  73,  16, -83,   9, -62, -77, -58, -79, -72, -50,  71, -57, -67, -52,  20, -72, -86, -74;
/M: SY='D'; M=  31, -72,  58, -48, -79,   7, -59, -78,  37, -77, -70, -47, -66, -50,  30,  46, -52, -70, -81, -68;
/M: SY='K'; M= -58, -74, -57,  16, -70, -68, -60, -64,  60,  19, -57, -55,  40,  35, -46,  27,  21, -64, -76, -65;
/M: SY='W'; M= -68, -86, -81, -65, -48, -73, -79, -63, -63,  11, -60, -75, -74,  56, -66, -66,  28, -71, 155, -38;
/I:         I=-28; MD=-71;
/M: SY='N'; M= -66, -79,  25,  55, -79, -74, -63, -62,  12, -72, -69,  59, -73, -55, -61, -61, -60,  39, -93, -75; D=-28;
/I:         I=-28; MD=-71;
/M: SY='G'; M= -70, -96, -71,  39,-102,  71, -84,-108, -78,-102, -93, -70, -83, -74, -87, -70, -84,-100, -94, -95; D=-28;
/I:         I=-28; MI=-71; IM=-71; DM=-71;
/M: SY='T'; M=  17, -68, -53,  29, -76,  49, -62, -74, -57, -75, -68,  29, -64, -54, -64,  37,  51, -66, -81, -71;
/I:         I=-30; MD=-77;
/M: SY='E'; M= -64, -81,  63,  78, -87, -69, -56, -87, -51, -84, -79,  38, -65, -46, -60,  15, -58, -81, -92, -76; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='E'; M= -61, -76,  55,  73,  47, -69, -57, -75,  16, -69, -69, -51, -63, -46, -54,  27, -56, -71, -73, -56;
/M: SY='V'; M= -52, -65, -77, -74, -56, -81, -82, -23, -71, -43, -45, -71, -75, -74, -74, -59,  42,  96, -88, -62;
/M: SY='Q'; M= -60, -78, -65, -48, -67, -75, -58,  36, -52,  10, -46, -60, -71, 108, -52, -57, -60,  23, -74, -59;
/M: SY='V'; M= -58, -67, -84, -76, -49, -83, -73, -25, -74,  46,  72, -78, -79, -71, -74, -70, -56,  77, -80, -57;
/M: SY='M'; M= -65, -75, -74, -68, -53, -79,  77,  45, -59,  26,  94, -65, -74, -58,  34, -69, -62, -43, -78, -50;
/M: SY='A'; M=  61, -67, -71, -65, -67,   8, -71, -46, -57, -57, -55, -65, -72, -61,  42, -52, -55,  59, -79, -67;
/M: SY='W'; M= -61,  88, -84, -78, -47, -80, -76, -39, -74,  24, -48, -78, -83, -75, -76, -70, -61,  59, 102,  36;
/M: SY='K'; M= -59, -78, -51,  47, -81, -68, -58, -76,  59, -76, -67, -53,  57,  49, -44,  15,  19, -72, -77, -69;
/M: SY='P'; M= -65, -83, -55, -56, -83, -62, -60, -74, -58, -84, -70,  74, 112, -61, -69, -57, -55, -79, -84, -80;
/M: SY='D'; M= -61, -80,  75, -52, -75,  53, -62,  33, -53, -69, -66, -48, -70, -57,  46, -57, -62, -63, -82, -68;
/M: SY='G'; M=  44, -72, -62, -58, -80,  66, -66, -79,  63, -78, -68, -52, -66, -54, -50, -49, -60, -71, -74, -72;
/M: SY='P'; M= -58, -73, -62, -59, -67, -67, -65, -55,  13,  19, -56,  25,  77, -60, -63,  27,  30,   9, -80, -68;
/M: SY='V'; M=  36, -71, -71, -61, -65, -70, -71,  17,  36, -54, -52, -66,  26, -60,  20, -58, -55,  60, -79, -65;
/M: SY='E'; M= -59, -74, -52,  63, -68, -76, -59, -57, -46,  12, -55, -59, -66,  34,  46, -55,  42,  17, -79, -64;
/M: SY='N'; M=   3,  68, -60, -68, -55, -65, -55,  14, -62, -53,  71,  75, -76, -61, -66, -57, -54,   9, -73,  47;
/M: SY='H'; M=  19, -71, -68, -67, -64,  30,  83,  24, -67, -54, -52, -58, -71, -64, -68, -55,  19,  50, -84, -58;
/M: SY='Q'; M= -61, -82, -56, -38, -84, -69, -51, -77,  60, -73, -60, -50, -66, 108,  38, -52, -61, -76, -72, -62;
/M: SY='T'; M= -57, -68, -67, -68, -51, -72, -65,  53, -65,   1, -48, -58, -68, -63, -69,  28,  76, -41, -69,  47;
/M: SY='K'; M= -57, -70, -60, -52, -66, -68, -61, -60,  63,  23, -54, -52, -65,  34, -46,  28,  60, -58, -77, -63;
/M: SY='P'; M= -61, -84, -65, -59, -82,  30, -70, -74, -63, -81, -70, -64, 112, -66, -74, -56,  33, -75, -79, -80;
/M: SY='G'; M=  20, -73, -58, -70, -81,  88, -65, -84, -64, -83, -72,  51, -69, -63, -71, -47, -61, -77, -77, -76;
/M: SY='Y'; M= -60, -74, -73, -68, -48, -76, -60,  46, -57,   1,  48, -66, -75, -59,  45,  26, -56,  21, -64,  60;
/M: SY='F'; M= -66, -72, -83, -79,  83, -82, -64,  30, -74, -39,  47, -76, -81, -76, -73, -71, -61,  41, -50,  61;
/M: SY='K'; M=  27, -70, -58, -53, -74, -61, -62, -63,  60, -70, -63,  29,  39, -52, -49,  28,  21,   7, -80, -68;
/M: SY='I'; M= -60, -70, -72, -73, -54, -80, -76,  81, -69,   4, -42, -63, -68, -69, -75, -55,  76, -30, -78, -59;
/M: SY='D'; M= -65, -80,  85, -45, -79, -66, -60,  11, -58, -74, -69,  27,  75, -59, -68, -56,  19, -67, -90, -72;
/M: SY='T'; M= -57, -73,  55,  17,  33,  56, -64, -73, -60, -71, -69, -48, -66, -60, -68, -49,  58, -68, -76, -61;
/M: SY='G'; M= -55, -78, -47,  72, -83,  72, -62, -87,  29, -81, -73, -52, -62, -48, -56, -53, -64, -80, -76, -74;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='K'; M= -58, -73, -51,  43, -76, -69, -58, -75,  70, -74, -66, -50, -62, -43,  37,  16,  51, -68, -78, -66;
/M: SY='V'; M= -56, -70, -74, -71, -58,  29, -76,  41,  14,   2, -47, -65, -73, -68, -67, -60,  19,  63, -79, -63;
/M: SY='Q'; M= -53, -78, -63, -58, -79,  80, -60, -75, -58, -69,  57, -52, -68,  81, -61, -51, -65, -74, -73, -68;
/M: SY='S'; M=  46, -64, -68, -65,  35, -61, -68, -51, -65,  -1, -55, -59, -69, -62, -68,  53,  29,  23, -73, -56;
/M: SY='I'; M= -57, -73, -80, -80, -55,  29, -83,  75, -76, -41, -43, -71, -75, -75, -79, -66, -57,  66, -79, -62;
/M: SY='S'; M=   8,  54, -61, -62, -75,  23, -65, -72, -61, -74, -68, -51,  28, -58, -67,  73,  43, -64, -83, -71;
/M: SY='H'; M= -65, -74, -76, -69, -51, -80,  63,  17, -72,  62, -38, -73,  52, -67, -72, -70, -61,  21, -78, -55;
/M: SY='D'; M= -66, -78, 106, -39, -76, -68, -59,  34, -58, -68, -69, -41, -67, -58, -66, -56,  20, -61, -95, -67;
/M: SY='Y'; M= -72, -77, -75, -75,  82, -80,  49,  14, -70, -47, -49, -70, -82, -69, -67, -69, -66, -54, -39, 100;
/M: SY='P'; M= -57, -83, -63, -55, -85,  47, -64, -78, -59, -82, -69, -59,  97,  56, -66,  12, -59, -79, -77, -76;
/M: SY='P'; M= -64, -83, -54,  40, -82, -72, -58, -79,  55, -78, -67, -57,  73,  35,  53, -59, -60, -77, -76, -70;
/M: SY='G'; M= -51, -77, -67, -77, -75,  95, -73,  33, -71, -71, -65, -53, -69, -68, -78, -52, -66, -64, -74, -73;
/M: SY='T'; M= -49, -63, -52, -58, -71, -58, -59, -66, -55, -71, -65,  52, -63, -55, -62,  66,  85, -59, -87, -67;
/M: SY='S'; M= -42, -66, -57, -59, -76,  32, -61, -76, -59, -79, -71, -45, -64, -51, -63, 101, -39, -69, -81, -68;
/M: SY='G'; M= -49, -74, -63, -73, -80,  96, -70, -83, -67, -81, -72, -49, -66, -66, -75, -47,  41, -76, -76, -75;
/M: SY='S'; M= -44, -65, -59, -59, -66, -54, -60, -63, -60,  19, -60, -49, -66, -51, -63, 101, -39, -60, -80, -64;
/M: SY='P'; M= -64, -86, -64, -53, -83, -68, -67, -73,  36, -81, -69, -65, 115, -60, -61, -59,  17, -75, -79, -78;
/M: SY='I'; M= -63, -76, -82, -76,  36, -84, -80,  78, -75, -40, -43, -76,  52, -76, -79, -70, -58,  46, -71, -54;
/M: SY='I'; M= -63, -73, -79, -76,  37, -84,  63,  68, -74,  13, -40, -71, -77, -72, -74, -70, -59,  49, -73, -48;
/I:         I=-30; MD=-77;
/M: SY='N'; M=  49, -73,  53, -56, -83, -60, -61, -77, -61, -81, -74,  72, -73, -61, -68, -50,  19, -71, -94, -76; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='S'; M= -58, -73, -66, -57, -59, -71, -62,  24,  40,  43, -47, -59, -71,  33,  19,  44, -54, -51, -74, -60;
/M: SY='N'; M=  26, -73,  58, -44, -80, -60, -53, -77,  41, -78, -68,  66, -68,  34,  22, -50, -55, -73, -84, -68;
/M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='E'; M= -63, -79,  34,  64, -80, -68,  49, -82,  16, -77, -68,  51, -65,  35,  35, -54, -58, -78, -84, -65;
/M: SY='V'; M= -51, -67, -77, -73, -56, -77, -80,  29, -72, -43, -45, -70, -75, -71, -74,  35, -48,  89, -85, -62;
/M: SY='I'; M= -59, -72, -85, -80, -50, -87, -84,  78, -77,   7, -37, -78, -77, -76, -79, -71, -55,  70, -79, -58;
/M: SY='G'; M= -49, -75, -67, -76, -77,  95, -73, -67, -70, -74, -68, -54, -70, -69, -77, -52, -65,  29, -76, -75;
/M: SY='L'; M= -69, -70, -86, -78,  71, -85, -68, -36, -78,  78, -34, -82, -85, -75, -75, -76, -64, -43, -60, -40;
/M: SY='Y'; M= -67, -81, -69, -74, -25,  29, -41, -61, -66, -57, -53, -67, -80, -62, -65, -63, -66, -65, -32, 127;
/M: SY='G'; M= -49, -77, -64, -76, -83, 103, -71, -91, -70, -86, -75, -50, -68, -67, -77, -49, -68, -84, -74, -78;
/M: SY='N'; M= -64, -73, -41,  38, -54, -60, -43, -71, -50, -73, -64, 102, -72, -49, -57, -51, -53, -73, -64,  77;
/M: SY='G'; M= -47, -74, -63, -72, -81,  96, -69, -87, -67, -85, -74, -49, -67, -63, -74,  37, -61, -81, -75, -76;
/M: SY='V'; M= -61, -70, -85, -80,  66, -85, -79,  44, -77,   6, -41, -78, -80, -79, -77, -70, -57,  72, -67, -45;
/M: SY='Q'; M= -62, -75, -65,  25,  40, -78, -59, -44, -55,   2, -49, -67, -75,  56,  20, -63, -60,  49, -62,  48;
/M: SY='I'; M= -61, -71, -74, -72, -48, -81,  47,  53, -70,  31, -41, -67, -74, -67, -71, -61,  45,  33, -72,  36;
/I:         I=-30; MD=-77;
/M: SY='G'; M= -57, -83, -65,  14, -88,  88, -72, -95, -64, -89, -79, -57, -73, -65,  16, -57, -73, -88, -80, -81; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='W'; M= -60, -81,  61,  78, -75,   7, -59, -83, -51, -78, -75, -52, -62, -46, -60,  11, -60, -79,  92, -63;
/I:         I=-28; MD=-71;
/M: SY='N'; M= -68, -85,  22, -68, -92,  56, -67, -94,  13, -95, -84,  69, -80, -66, -69, -60, -68, -92, -94, -84; D=-28;
/I:         I=-28; MI=-71; MD=-71; IM=-71; DM=-71;
/M: SY='P'; M=   2, -83, -73, -65, -80, -75, -74,  21,  27, -74, -69, -66,  52, -63,  20,  21,  18, -64, -87, -76; D=-28;
/I:         I=-28; DM=-71;
/M: SY='Y'; M= -65, -76, -70, -72,  56, -72, -44, -57, -66, -53, -53, -67, -80, -62, -64,  35, -59, -61, -35, 116;
/M: SY='V'; M= -61,  52, -76, -71,  48, -81,  63,  17, -63, -47, -49, -67, -79, -68,  29, -66, -59,  65, -75, -48;
/M: SY='S'; M=  29, -63, -57, -57, -74, -49, -60, -72, -58, -75, -69, -47, -64, -50, -62, 101, -38, -63, -81, -67;
/M: SY='P'; M=  35, -71, -71, -66, -62, -66, -71,  45, -67,  13, -49, -66,  52, -64, -72,  39, -52,  13, -77, -65;
/M: SY='I'; M= -64, -77, -78, -77, -52, -86,  72,  94, -74, -37, -39, -69, -74, -69, -75, -70, -59,  26, -79, -53;
/M: SY='A'; M=  61, -63, -67, -63, -64, -59, -68, -50, -64,  20, -52, -60, -69, -61, -68,  41,  34,  19, -79, -65;
/M: SY='Q'; M= -56, -80,  46, -39, -86,  18, -52, -79, -47, -75, -65, -46, -66, 108, -49,  28, -57, -77, -78, -65;
/M: SY='G'; M=  47, -70, -65, -69, -79,  84, -70, -79, -66, -78, -69, -53, -67, -64, -73, -45,  16, -69, -75, -75;
/M: SY='D'; M= -58, -76,  56,  50, -80, -64, -54, -81,  38, -79, -72,  29, -64, -43,  32,  40, -53, -75, -84, -68;
/M: SY='P'; M= -60, -77, -67,  16, -65, -78, -71,  37,  13, -54, -52, -68,  62, -59,  29, -64, -57,  56, -80, -66;
/M: SY='K'; M= -56, -76, -51,  43, -80,  18, -59, -76,  55, -76, -67, -51,  29,  44, -46,  13,  33, -72, -77, -69;
/M: SY='Q'; M=  38, -76,  56,  49, -78, -66, -57,   8, -48, -69, -64, -52, -65,  57,  20, -52, -58, -63, -80, -67;
/M: SY='E'; M= -58, -73, -47,  84, -65, -78, -62, -49, -53,  20, -54, -63, -64, -48, -61, -59,  20,  40, -81, -66;
/M: SY='P'; M=   6, -74,  48,  30, -68, -70, -65, -54, -60,  20, -56, -59,  62, -59, -67, -57,  19,  19, -83, -68;
/M: SY='N'; M= -55, -68,  25,  16, -73, -58, -54, -63, -53, -71, -66,  85, -67, -52, -60,  41,  31,  16, -90, -69;
/M: SY='P'; M= -61, -74, -57, -59,  38, -63, -61, -67, -59, -71, -65,  60,  87, -62, -68,  16,  42, -68, -76, -61;
/M: SY='E'; M= -61, -76,  33,  74, -71, -76, -58, -61, -45,  -2, -60, -56, -65, -46,  43, -57,  20,  18, -82, -67;
/M: SY='P'; M=  14, -75, -64,  29, -62,  30, -67,  12, -64, -60, -57, -66,  57, -62, -70, -58, -58,  40, -70,  36;
/I:         E1=0; IE=-255; DE=-255;
» More

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_10 which contains 546'790 sequence entries.


Total number of hits 44 in 44 different sequences
Number of true positive hits 44 in 44 different sequences
Number of 'unknown' hits
Number of false positive hits
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotic viruses
Maximum number of repetitions [info] 1
Feature key [info] DOMAIN
Feature description [info] Peptidase S7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
44 sequences

POLG_DEN1B  (P27909), POLG_DEN1S  (P33478), POLG_DEN1W  (P17763), 
POLG_DEN26  (P29990), POLG_DEN27  (P29991), POLG_DEN28  (P14337), 
POLG_DEN2J  (P07564), POLG_DEN2N  (P14340), POLG_DEN2P  (P12823), 
POLG_DEN2Q  (Q9WDA6), POLG_DEN2T  (P27914), POLG_DEN3C  (Q99D35), 
POLG_DEN3I  (Q5UB51), POLG_DEN3M  (Q6YMS3), POLG_DEN3P  (P27915), 
POLG_DEN3S  (Q6YMS4), POLG_DEN4D  (P09866), POLG_DEN4H  (Q2YHF2), 
POLG_DEN4P  (Q58HT7), POLG_DEN4S  (Q5UCB8), POLG_DEN4T  (Q2YHF0), 
POLG_JAEV1  (P27395), POLG_JAEV5  (P19110), POLG_JAEVJ  (P32886), 
POLG_KUNJM  (P14335), POLG_LANVT  (P29837), POLG_LIV    (P22338), 
POLG_MCFA   (P33515), POLG_MVEV5  (P05769), POLG_POWVL  (Q04538), 
POLG_STEVM  (P09732), POLG_TBEVH  (Q01299), POLG_TBEVS  (P07720), 
POLG_TBEVW  (P14336), POLG_WNV    (P06935), POLG_YEFV1  (P03314), 
POLG_YEFVA  (Q6DV88), POLG_YEFVC  (Q6J3P1), POLG_YEFVE  (Q074N0), 
POLG_YEFVF  (Q89277), POLG_YEFVI  (Q98803), POLG_YEFVN  (Q1X881), 
POLG_YEFVT  (Q9YRV3), POLG_YEFVU  (Q1X880)
» More

PDB
[Detailed view]
14 PDB

2FP7; 2GGV; 2IJO; 2M9P; 2M9Q; 2WHX; 2WV9; 2WZQ; 2YOL; 3E90; 3L6P; 3LKW; 3U1I; 3U1J
» More

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission