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PROSITE entry PS51635


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General information about the entry

Entry name [info] PNPLA
Accession [info] PS51635
Entry type [info] MATRIX
Date [info] 01-SEP-2016 CREATED;
01-SEP-2016 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51635
Associated ProRule [info] PRU01161

Name and characterization of the entry

Description [info] Patatin-like phospholipase (PNPLA) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=181;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=176;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2211545; R2=0.0079003; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1048; N_SCORE=10.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=542; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-23; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='L';  M=-53,-57,-71,-64, -5,-40,-57, 23,-64, 78, 17,-67,-69,-58,-63,-61,-18,-25,-58,-40;
/M: SY='S';  M= 18, 43,-56,-54,-15,-52,-57,  1,-53,-25,-42,-47,-58,-51,-57, 52, 27, 45,-67, -7;
/M: SY='M';  M=-54,  9,-73,-66, 60,-72,-56, 35,-64, 52, 61,-65,-68,-61,-62,-62,-50, -5,-51,-30;
/M: SY='D';  M=  0,-59, 60,  3,-67, 28,-46,-66,-11,-67,-60, -5,-52, -4,-48, 58,-11,-60,-72,-57;
/M: SY='G';  M=-17,-62,-51,-61,-69, 94,-57,-75,-56,-72,-62,-37,-55,-52,-62, 17,-51,-68,-62,-64;
/M: SY='G';  M=-16, 45,-53,-62,-69, 92,-58,-75,-57,-71,-61,-39,-57,-54,-64,  0,-52,-67,-63,-65;
/M: SY='G';  M= 24,-60,-53,-59,-64, 83,-59, -2,-56,-61,-54,-41,-56,-53,-62, -1,-18,-26,-63,-61;
/M: SY='T';  M= 28,-54,-56,-52, 37,-53,-52,  9,-49,-23, 37,-47,-57, -6,-11, 26, 48, -4,-57, -4;
/M: SY='R';  M=-25,-63,-56,-47, 39,-63,-46,-46, 28, 24,  3,-50, -5,-41, 68,-15,-19,-47,-53, -1;
/M: SY='G';  M=  1,  4,-50,-17,-69, 92,-57,-75,-55,-71,-61,-39,-55,-52,-62,-14,-53,-67,-62,-64;
/M: SY='I';  M= 17,-60,-13,-61, -6,-65,-59, 62,-61, 29,  7,-61,-63,-57,-62,-54,-46, 25, 23, 24;
/M: SY='Y';  M= 28,-59,-60,-59, 30,-19,-46, 20,-55,-19,-39,-55,-63,-52,-56, 12,-17,  9, 31, 78;
/M: SY='H';  M= -1,-63,-48,-45,-50,-56,113,-20,-48, -4,  5,-40, 23, -5,-47,  1,  2,-25,-71,  7;
/M: SY='I';  M= 37,-57,-65,-60, 13, -9,-61, 43,-59, 32,  6,-59, -5,-57,-62,-48,-19, 18,-60,-45;
/M: SY='G';  M= -2,-62,-49,-52,-69, 85,-53,-71,-21,-68,-58,  0,-55, 38,-54,-35,  0,-65,-62,-61;
/M: SY='V';  M= 40,-53,-65,-59,-45,-59,-64, 24,-58, -3, 18,-59,-61,-57,-60,-20,-15, 69,-69,-50;
/M: SY='L';  M= 31,-56,-66,-60, -5,-62,-57, 26,-60, 58,-26,-61,-64,-56,-61,-50,  1, 10,-57,  6;
/M: SY='Q';  M= 14,-61, 21, -1,-62,-31,-44,-23, 37,-15,-49, 32,-55, 38, 31,  9,-17,-53,-66,-53;
/M: SY='A';  M= 50, 28,-48, 26,  6, -8,  2,-52, -5,-25,-47,-47,-56,-43,-12, -2, 10,-27,-56, 29;
/M: SY='L';  M=-54,-58,-72,-66, -2,-74,-59, 37,-66, 77,-18,-70,-70,-60,-64,-64,-49, -3,-58,-40;
/I:         I=-10; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='D';  M=-36,-93, 22,-10,-26,-15,-75,-37,-68,-50,-80,-21,-17,-17, -2,-23,-74,-83,-95,-80; D=-10;
/I:         I=-10; DM=-25;
/M: SY='H';  M=-74,-90, 16, -6,-90,-80, 22,-88, -3,-48,-78,-19,  4, -8,-25, -9, -8,-85,-98,-78; D=-10;
/I:         I=-10; DM=-25;
/M: SY='N';  M=  8,-83,-23,  5,-82,  1, -3,-75,-69,-23, -2, 20,-80,-18,-74,-64,-69,-38,-92,-78; D=-10;
/I:         I=-10; DM=-25;
/M: SY='P';  M= 19,-65,-53,  3,-22,-59, 24,-25, 24,  8,-43,-53, 44,-11,  0,-48,-26, -7, 26, 28; D=-10;
/I:         I=-10; DM=-25;
/M: SY='R';  M= 14,-64,  2, 47,-20,-58,  3,  4, 30,-18,-48,-14,  7,-34, 47,-45,-47,-50,-64,-51;
/M: SY='H';  M= -8,-62,  1,-45,-20,-62, 39, 17, 14, 30, 27,-48,-14, 36, 16,-49,-14,-20,-61, -1;
/M: SY='D';  M=  5,-61, 35,-18,-14, 34, 24,  9,  7, -6,-45,-10,-12, -9,-50,-19,-46, 14,-66,-50;
/M: SY='D';  M=-27,-61, 50,-16,-18,-58,-47, 21,-20, 21,-38, 22,-60, 24,-51, -2,-43, 18,-63, 17;
/M: SY='Y';  M=-52,-64, 24, -3, 12,-30,-46,-21, -4, 25,  4,  7, 28,-12, 28,-50,-17,-13,-56, 30;
/M: SY='F';  M= -1,-61,-66,-59, 71,-64,-60, 37,-59,-17,  2,-60, 50,-14,-62,-52,-12, 23,-50,-32;
/M: SY='D';  M=-52,-65, 84,-11,-68,-53, 32,-67, 41,-66,-59, 24,-54, -4, 13,-19,-17,-38,-77,-53;
/M: SY='I';  M=  8,-59,-61,-57,-43,-36, -1, 46,-21,  1, 35, -6,-61,-51, 18,-49,  1, 36, 31, -8;
/M: SY='I';  M= -7,-60,-71,-67, 50,-71,-64, 73,-64,  7,-28,-64,-65,-63,-65,-57,-46, 35,-52,  1;
/M: SY='A';  M= 50, 44,-53,-53,-54, 35,-53,-27,-52,-17,-49,-44,-57,-48,-56, 44, -3,-46,-61, 11;
/M: SY='G';  M=-37,-64,-52,-64,-70,100,-59,-78,-57,-74,-63,-38,-56,-55,-65,-37,-56,-72,-61,-65;
/M: SY='T';  M= 13, 41,-48,-50,-56,-49,-55,-21,-48,-51,-48, -3,-53,-48,-54, 47, 75, 12,-73,-54;
/M: SY='S';  M=-13,-53,-44,-46,-63, 19,-48,-63,-46,-66,-58,-33,-52,-38,-50, 97,-26,-55,-69,-55;
/M: SY='A';  M= 54,-53,-57,-54,-52,-13,-58, 40,-53,-40, 36,-48,-55,-50,-57, 16, 33,  9,-66,-52;
/M: SY='G';  M=-37,-64,-52,-64,-70,100,-59,-78,-57,-74,-63,-38,-56,-55,-65,-37,-56,-72,-61,-65;
/M: SY='A';  M= 65,-53,-51,-50,-65, 46,-54,-60,-50,-62,-54,-41,-54,-45,-55, 51,-38,-50,-64,-59;
/M: SY='I';  M=-51,  6,-71,-65,  9,-73,-62, 67,-63, 46, 28,-65,-66,-10,-63,-60,-47, 23,-60,-41;
/M: SY='V';  M= -9,-56,-61,-61,  5,-64,-58, 35,-58, 35, 25, 20,-63,-57,-60,-50, 17, 47,-64,-44;
/M: SY='A';  M= 76, 29,-55,-52,-61, 34,-58,-53,-52,-31,-49,-47,-56,-50,-57,-18,  2,-19,-65,-59;
/M: SY='A';  M= 60, 30,-56,-52,  1, -1,-55,-20,-52, -2,  1,-47,-57,-49,-56, 36,  3,-20,-63,-51;
/M: SY='M';  M= 43,-55,-65,-59,  4,-10,-55,  1,-58, 44, 69,-59,-62,-53,-59,-48,-46,  7,-59,-44;
/M: SY='L';  M=-29, 16,-69,-64, 21,-30, -7, 28,-62, 57,-25,-64,-69,-59,-61,-59,-50,  9, 22, 43;
/M: SY='A';  M= 50, 38,-59,-56, 10, 13,-59,  0,-55,-11,-42,-50,-59,-53,-59, 15,  3, 28,-63,-50;
/M: SY='C';  M= 32, 58,-56,-53,-15,-54,  5, 11,-24,  1,-41,-47,-58,-51,-28, 18, 45, 12,-68,-50;
/M: SY='G';  M=  7,-62, 14, -8,-21, 55, -8,-64,-17,-36,-54, -6,-13, -4, 31, 12,-21,-59,-62, -9;
/I:         I=-3; MD=-8;
/M: SY='R';  M=-26,-78,  1,-55,-61,-70, 17,-30, -2,-39,-15,-16,  2, -8, 36, -8,-10,-65,-69, 34; D=-3;
/I:         I=-3; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='A';  M= 21,-85,-28,-75,-77,-19,-78,-31,-17,-27, -1,-75,-14,-73,-27,-37,-71,-38,-86,-13; D=-3;
/I:         I=-3; DM=-8;
/M: SY='R';  M=-16,-91, 23,-11,-91,-82,-71,-90, 14,-52,-80,-65,-25,-61, 32,-32,-72,-85,-94,-81; D=-3;
/I:         I=-3; DM=-8;
/M: SY='E';  M=-78,-95, -1, 46,-84,-87,-68,-92,  4,-87,-15,-20,-78,-56,  4,-73,-75,-89, 22,-11; D=-3;
/I:         I=-3; DM=-8;
/M: SY='I';  M=-40, -3,-81,-32,-23,-88, -4, 18,  2,-23,  1,-77,-10,-73,-72,-75,-22,-60, 18,  8; D=-3;
/I:         I=-3; DM=-8;
/M: SY='R';  M= -7,-83, -8,-31,-80,-79,-12,-31,-66,-37,-69,-20,-32,-17,  3,-14, -4,  0,-95,-76; D=-3;
/I:         I=-3; DM=-8;
/M: SY='P';  M= -8,-81,-70,-29, -6,-13,-70,-27, 21,-40,  7,-22, 22, -8,-61,-32,-64,-20,-79,-68; D=-3;
/I:         I=-3; DM=-8;
/M: SY='C';  M=-31, 27,-75,-68, 26,-75,-66,-23,  0,  5, 26,-67,-78,-15,-26,  4,-25,-20,-69, -2; D=-3;
/I:         I=-3; DM=-8;
/M: SY='Y';  M=-36,-77,-28,-75, 21,-34,-64,  4,-71, 10, 21,-73,-81,-70,-24,-69,-31,-11, 26, 47; D=-3;
/I:         I=-3; DM=-8;
/M: SY='F';  M=-15,-67, 12, -4, 37, 14,-54,-59,-53, -7,-54, 16,-66,-15, -4, -5, 13,-58,-63, -4; D=-3;
/I:         I=-3; DM=-8;
/M: SY='E';  M=-55,-71, 39, 49,-21,-63, 20,-34, 18,-66,-61,-44, -4,-39, 16,  3,  1,-64,-71, -8; D=-3;
/I:         I=-3; DM=-8;
/M: SY='W';  M=  7, 15, -5, 23,-17,-10, 26,  2, 17, -9,  5,-15,-60, 12,-48,-49,-17,-29, 57,-49; D=-3;
/I:         I=-3; DM=-8;
/M: SY='W';  M=-14,  4, 21,-22,  2, 13,-54,  9, -2, 21, 24,  6,-15,-51,-24,-20,-18,-45, 48,-47; D=-3;
/I:         I=-3; DM=-8;
/M: SY='D';  M=-25,-64, 38, 28,-62,  6, 32,-58,-14,-18,  1,-12, 25, -6, 27, 24,-23,-30,-70,-53;
/M: SY='E';  M=-23,-65, 38, 58,-24,-26,-43,-66, 26,-64,-57, 28, 30, 27,-11,-19,-16,-62,-68,-56;
/M: SY='I';  M=-12,  6,-65,-34,  7,-67,-60, 51,-31, 31, 16,-59,-62,-56,-60,-51, 27, 18, 48, -3;
/M: SY='F';  M=-18,-59,-68,-64, 79,-67,-52, -3,-34, 45,-30,-18,-70,-61,-59,-58,-51,-17, 29, 37;
/M: SY='D';  M=-13,-62, 45, 19,-62,-53, -4,-25, 26,-23,-51,  4, 13, 20,  6, 15, 30,-53,-70,-54;
/M: SY='A';  M= 26,-58, -2,-49,-14, -8,-55, 18,-20, 10,  3,-50,  9, 11,-21,  9, -3, 19, 15,-48;
/M: SY='D';  M= -7,  5, 36,-16, -3,-54,-50,-43,-20, 13,-44,-12, 12,  8,-19, 33, 21, 11,-68,-49;
/M: SY='R';  M= -7,-61,  9,-40,-16,-13,-43,-56, 40,-57,-51, 11,-57, -4, 45, 28,  0,-16,-56, 36;
/M: SY='P';  M=-20,-65, -6, -7, 19, -4,  2,-24, 10,-16,  2,-47, 49, 26, 19,-25,  0,-26,-55, 26;
/I:         I=-7; MD=-19;
/M: SY='W';  M=  5,-65,-32,-61, 15, 14,-63,-18, -3, -4,-48,-57,-66,-58,-21, -9,  7, 19, 51, -3; D=-7;
/I:         I=-7; MD=-19;
/M: SY='G';  M= -9,-74, -2, -4, 13, 15,-63,-18, -2,-37, -4,-15,-70,-56, -1,  7,-28,-62,-74,-60; D=-7;
/I:         I=-7; MD=-19;
/M: SY='Q';  M= -8,  5, -3,-26,  6,-74,-70,-29,-68,-45,-66,-65,-12, 16,-72,  9, -6,-17,-79,-11; D=-7;
/I:         I=-7; MD=-19;
/M: SY='Y';  M=-76,-91,-29, -9, -7, 10,-76,-32,-19,-14,-70,-18,-30,-75,-78,-75,-77,-39,-80, 10; D=-7;
/I:         I=-7; MI=0; MD=-19; IM=0; DM=-19;
/M: SY='R';  M=-65,-77,-69,-59,-59,-78,-61,-22, 25, 16,-51,-63,-76,  5, 44,-34,-23,-15,-72,  4; D=-7;
/I:         I=-7; DM=-19;
/M: SY='R';  M=-57,-70,-63,-21, -3,-71,-59,-10, -4,-12, -3,-58,-15,-53, 40,  5, 22,  2,-68,  9; D=-7;
/I:         I=-7; DM=-19;
/M: SY='W';  M=-61,  3,-68,-22, 41,-34, -1,-29,  0,  3,-48,-62,-72,-11, 15,-30,-29,  1, 66,  7; D=-7;
/I:         I=-7; DM=-19;
/M: SY='W';  M=-52,-67,-53, 21, 18,-30,-57, -9,-27, -8,-49,-17, 23,-11, 15,  7, 22, -5, 46,-48; D=-7;
/I:         I=-7; DM=-19;
/M: SY='F';  M=-14,-61,-56,-23, 40,  4,  3, -8, 17, 18,-38,-22,-62, -9, 21,-23,-21,  7,-51, 28;
/M: SY='G';  M=-42, 24,-47,  1,-18, 73, -1,-63,-17,-24,-54, 12,-57,-47,  2,-22, 10,-37,-64,-56;
/M: SY='P';  M= 23,  3,-48,-47,-64, 36,  2,-28,-17,-41,-52, 23, 42, -1, 27, 22,-22,-55,-66,-57;
/M: SY='L';  M=-52,-61,-61,-19, 19,-32,-51, -3,  9, 46, 39,-58,-14, -3, 16,-56,-49, 14, 13,  9;
/M: SY='Y';  M=-53,-62,-25, -6, 56, -6, 60, -2,-54, 18,-36,-50,-63,-51,-54,-21, 13,-43,-43, 61;
/M: SY='P';  M=-30,-66, 50,-13,-66,-21,-47,-64, -4,-66,-58, 12, 67, -5, 21, 24,  7,-62, 37,-56;
/M: SY='G';  M=  4, -5,-16, 10,-58, 56,  3,  3,-14,-32,-52,-17,-11,-44,-53, 38,-43,-52,-62, -3;
/M: SY='H';  M=-48,  6, 26, -3,  4,-34, 46,-12, 17,-30,-48,  8,-57,-41, 12, 29,  2,-19, 31, 28;
/M: SY='N';  M=-47,-62,-11, 22,-52, -6, 36,-25, 12,-34,  0, 38,-56,-38, 31, -6, 22, -3, 29, 15;
/M: SY='F';  M=-10,-59,-31,-60, 54,-66,-57, 19,-22, 37, 40,-61,-16,-57,-22,-55,-15, 16, 48,-32;
/M: SY='M';  M=  7,-61,  6, 38,  1, -4,  7,-15,-43,-27, 40, 24,-11, 12,-18,-16,-22, 11,-63, -9;
/M: SY='W';  M=-25,-65,  5, 14,-61,  5,-47,-63, 42,-40,-53,  3, -8, 38, 35,-18, 14,-60, 70,-49;
/M: SY='M';  M= 13, -1,-15,-20,-12,-17, 23,  8,-22, 29, 32,-50,-59,-12,-18,-45, 32,  6, 16,-44;
/M: SY='V';  M=-24,  1,-70,-64,-36,-70,-61, 47,-62, 39, 48,-64,-65,-59,-62,-56,-14, 50, 14, -7;
/M: SY='R';  M=-13,-67,-43, 38,-59,-60, 24,-35, 29,-55, 15,-44,-56, 34, 71,-46,-50,-26, 22,-16;
/M: SY='K';  M=-13,-62, 32, 27,-62,  1,-43,-63, 39,-38,-54, 26,-53, 16, 20, 13, 13,-58,-66,-13;
/I:         I=-10; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='M';  M=-64,-73, -4,-27, 17,-79,  1, 14,-28, 20, 22,-64,-75,-62,  7,-29, -8,-17,-73,-52; D=-10;
/I:         I=-10; DM=-25;
/M: SY='F';  M= -3,-69, -1,-65, 35,-35,-67, 26,-65,  8, -1,-63,-11,-66,-30,-28, 11,-20,-67,-49; D=-10;
/I:         I=-10; DM=-25;
/M: SY='G';  M=-23,-73,-57,-25,-35, 59,-62,-76, 22,-44,-66,  3,-19,-55,-23,-15,-20,-72,-73,-68; D=-10;
/I:         I=-10; DM=-25;
/M: SY='D';  M= -7,-71, 45, 36,-27, -3, -2,-72,-52,-72,-68, 21,-63,-49,-60,  4,  1,-35,-83,-65; D=-10;
/I:         I=-10; DM=-25;
/M: SY='L';  M= -4,  6,-65,-32,-14,-70,-62, 23,-25, 33,-37,-28,-68,-58, -5,-53, 29,  7,-67, -9; D=-10;
/I:         I=-10; DM=-25;
/M: SY='T';  M=-45,  3,-44,  9, -2,-26,-49,-53,  9,-19,-49, 18, 17, -1, 13,  3, 68,-49, 13,-50;
/M: SY='F';  M=-54,-59,-20,-63, 62,-71,-55, 36,-60, 45, 40,-63,-68,-60,-21,-60,-49, 10,-48, 10;
/M: SY='E';  M=-16,-64,-42, 48, 17,-30, 32, 15, 19,-19,-44,-19,-55, 27, 18,-19,-15,-47,-56, 16;
/M: SY='D';  M=-46,-64, 63, 57,-69,-31,-42,-63,  0,-63,-57, -7,-50, 48,-41, 12, 18,-30,-72,-56;
/M: SY='A';  M= 30, 25, -1,-51,-18,-32, 29, 25,-53, -3,-41,-13, 28,-51,-57,  0, 26,  9,-68,-49;
/M: SY='W';  M= 11,  4,-62,-23,  9,-27,-51, -4,-53, 39,-33,-59,-65,-52,  2, -6,-48,  8, 63, 51;
/M: SY='P';  M=-50,-66,  5, 34,-18,-58,-46,-12, 41,-58,-52,  6, 47, 12, 41,-20,  2,-32,-65,-53;
/M: SY='R';  M=-10,-65, 11, 12,-27,-25,  3, -9,  9,-32,-51, 32, 51,-38, 53, -4,-45,-55,-67,-53;
/M: SY='T';  M=-47,-57, 12,-13, 25,-19,  7,  0,-51,  5,-40, 22,-16,-50,-55, -3, 46, 24,-61, 12;
/M: SY='G';  M= 17, 28,-21,-56, 21, 35,-56,-16,-56, 15,-41,-50,-15,-12,-59, 17,-45, 15, 12, -3;
/M: SY='C';  M=-28, 40,-61,-56,  6,-38, 26, 37, 14, 10,  8,-54,-64,-50, 12,-52,-20, 26,-55, 39;
/M: SY='P';  M=-49,  7,-23, 10,-56,-61, -1, 38,-19,-29,-43,-16, 75, -7, -1,-10,-13, 14,-68,-55;
/I:         I=-5; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='C';  M=-42, 60,  1,-73,-82,-79,-79,-43,-77,-82,-79,-67,-86,-17,-82, 22, 10,-39,-97,-18; D=-5;
/I:         I=-5; DM=-13;
/M: SY='Y';  M=-31,-79,-69,-36,  3,  9,-63,-64,-31, -5,-60,  2,-79, 12,-68,-10,-23,-34,-68, 31; D=-5;
/I:         I=-5; DM=-13;
/M: SY='D';  M=-65,-79, 48,-49,-24,  2,  0,-79,  0,-46,-69, 35,-13,-17, 29,-56,-60,-78,-84,-65; D=-5;
/I:         I=-5; DM=-13;
/M: SY='L';  M=-62,-71,-74,-27,-16,-40,-70, 35,-72, 46,-37,-20,-76,-68,-73,-31,-19, -4,-73,-55; D=-5;
/I:         I=-5; DM=-13;
/M: SY='T';  M=-22,-69,  5,-55,-69,-14, 25,-26,  6,-38,-58,-12,-24,-14,-58, -5, 44,  0,-84,-63; D=-5;
/I:         I=-5; DM=-13;
/M: SY='V';  M=-30,-69,-72,-69,-54,-76,-70, 31,-26,-13, -1,-26,-72,-65,-19,-26, 23, 41,-77, -9; D=-5;
/I:         I=-5; DM=-13;
/M: SY='S';  M=-12,  2,-62,-59,-69,-35,-62,-12,-53,-37,-61,  4, 16,-10, 17, 43,-19,-32, 32,-64; D=-5;
/I:         I=-5; DM=-13;
/M: SY='P';  M= 12,  1,-63,-21,-22,-13,  1,-26, -9,  0, -2,-58, 15, -9,-20,  5, -2,-56,-72,-18; D=-5;
/I:         I=-5; DM=-13;
/M: SY='P';  M=-18,-70,-61,-59,-69,-13,-65,-59,-60,-21,-10,-18, 64,-60,-67, 15, 47,-30,-79,-68; D=-5;
/I:         I=-5; DM=-13;
/M: SY='R';  M=-18,  0, -4,-59, 43,-69,-61,  2,-49,-53,-53,-15,-71,-57, 44,  3, -1,  5,-67,-48; D=-5;
/I:         I=-5; DM=-13;
/M: SY='W';  M=  1,-63,-23,-64,  4,-25,-68, 22,-29, 26,-37,-64,-68,-63,-64,-56, -1, 42, 52,-47; D=-5;
/I:         I=-5; DM=-13;
/M: SY='F';  M=  4,  9,-54,-52, 73,-54, 23,-48,  7,-30,-46, -8,-14,-50,-50, 37, 28,-47, 16,-30;
/M: SY='T';  M=-16, 28, 44,  9,-64, -6, 10,-62,-40,-61,-56,-13,-18, -2, 14, 40, 50,-55,-74,-55;
/M: SY='N';  M=-22,  5, 34,  2,-67, 16,  5,-66, 25,-64, -4, 41,  6, 25, 29,  7,-44,-63,-70,-55;
/M: SY='P';  M= 20,-62, 15, 36, -9,-57,-49, -8, -7,  8, -9,-49, 46, -8,-50,-20, -3,-19,-59, 14;
/M: SY='N';  M=-47, -5, 39,-13,-63, 14,-42,-35,-18,-27,-52, 67, -7, 37, -3, -2,  9,-30,-73,-56;
/M: SY='A';  M= 37,  5,-56,-15,-12,-22, 24, 15,-54, 22,-36,-16,-60,-51,-56,-22, 19, 16,-60, 16;
/I:         I=-23; MD=-58;
/M: SY='S';  M= 23,-59,-60,-57, 17,  6,-55, 16,-53, 22,-38,-52,-62,-52, -3, 31,-23, -2, 15, 14; D=-23;
/I:         I=-23; MD=-58;
/M: SY='N';  M=-50, -1,-20, 23,-56,-57, -7, -6,  8,-53, 17, 50, 37,  3,  2,-22, 13,  3,-67,  7; D=-23;
/I:         I=-23; MD=-58;
/M: SY='Y';  M=-47,-62, 20,-19,-46,-13,  1,-56,-19,-55, 17, 21, 12,  7,-14, 31, 35,-55,-54, 60; D=-23;
/I:         I=-23; MD=-58;
/M: SY='P';  M=-24,-64, 25, 10,-15,-62, 23,  3,-45, 14,-42,-47, 37, -5, 14,-21, 25,-10,-65, -4; D=-23;
/I:         I=-23; MD=-58;
/M: SY='T';  M=-32,-70,-67,-67, 28,-41,-65, 17,-64,-31,-11, -1,-70,-11,-68,-53, 51,-24, 45, 15; D=-23;
/I:         I=-23; MI=0; MD=-58; IM=0; DM=-58;
/M: SY='H';  M= 24,-63,-52,-21, 11,-10, 51,-62,-49,-61,-55,-13, 35,-48,  0, 33, 19,-57, 23,-49; D=-23;
/I:         I=-23; DM=-58;
/M: SY='P';  M=-50, 27, 17, -1,-18,-58,-50,-59,-45,-36,  1,-47, 66,-15, 14, 26, 22,-57,-64, 19; D=-23;
/I:         I=-23; DM=-58;
/M: SY='N';  M=-25,-62, 54,  7,-64,-50,  5,-64, 28,-64, -9, 65,-55, -5, 21,-18, 10,-61, 29,-52;
/M: SY='F';  M=  2, -5,  8, 21, 37, 30,  2,-19,-50,-24, 23,-47,-12, 16,-54,-45,-21, 17,-57, -7;
/M: SY='K';  M= -8,-62, 17, 37,-52,-58,-47, -6, 39,  9,-44, -8,  0, -4, -5,  2,-44, -1,-62,  6;
/M: SY='L';  M=-32,-58,-70,-62, 11,-69,-60, 39,-61, 48, 38,-64,-66, -3,-61,-28,-46, 42, 29,-39;
/M: SY='W';  M=  0,-68,-29,-54,-38,-56, -3, 23,  1,-15,-46,-55,-61,-48,-10, 30,-49,-47,132, 18;
/M: SY='D';  M=-28,-62, 56,  4,-64,-32,-43,-59, 13,-21,-53, 12,-18, 36, 28, 33, -7,-31,-71,-54;
/M: SY='A';  M= 75,-51,-59,-53,  0,-45,-59,  1,-54,-44,-42,-53,-58,-51,-57, -1,-39, 37,-61,-17;
/M: SY='C';  M=  5, 69,-67,-64,-42,-66,-66, 52,-62, 18,-30,-20,-66,-61,-65,-53,-43, 55,-69,-50;
/M: SY='R';  M=-21, 22,-10,-18,-47,-64,-46,  7,-11, 12,  3,-49,-63,-39, 79,-50,-19, -8,-60, 14;
/M: SY='A';  M= 67, 66,-55,-50,-59,-43,-54,-25,-49,-32, 20,-46,-57,-46,-14, 45,-37,-42,-67,-56;
/M: SY='S';  M=-31,-51,-44,-45,-60,-41,-48,-57,-44,-61,-55,-32,-50,-39,-50, 92, 54,-49,-71,-53;
/M: SY='C';  M=  9, 88,-55,-15,-52, -4,-55, 19,-53,-13, 41,-12,-60,-50,-58, 43,-15,-41, 25,-53;
/M: SY='A';  M= 62,-53,-53,-50, 27,  9,-52,-54,-49,-54,-51,-44,-55,-46,-21, 54,-18,-46,-57, -7;
/M: SY='I';  M= 25,-58,-64,-25, 31,-61,-60, 48,-58, 18,  4,-59, -5,-56,-61,-22,-17, 22, 26, -2;
/M: SY='P';  M=  4,-72,-53,-44,-71,-24,-57,-60,-50,-69,-57,-55,114,-52,-61,  0, -8,-61,-67,-68;
/M: SY='G';  M= -5,-59,-57,-61, 18, 63,-57,  9,-57, -4,-43,-46,-58,-56,-61,-18, 27,  5,-56, 11;
/M: SY='Y';  M=-26,-62,-64,-64, 32, 10,-47, 40,-59, 21,-32,-58,-66,-57,-60,-53,-13,  6,-39, 78;
/I:         I=-9; MD=-22;
/M: SY='F';  M=-29, 56,-69,-65, 79, -2,-54, -8,-62, 17, 37,-60,-70, -8,-61,-56,-53,-22,-44, 22; D=-9;
/I:         I=-9; MD=-22;
/M: SY='P';  M= 10,-66,-14, 19,-67, 26,-51,-29, 13,-63,-55,  1, 59,-42, 28,-16,-19,-28,-67,-61; D=-9;
/I:         I=-9; MD=-22;
/M: SY='P';  M= 14,-69,-19,-20,-19,-56,-57,-25,-14,-21,-52,-56, 94,-51,-22,  4,-46,-28,-67,-61; D=-9;
/I:         I=-9; MD=-22;
/M: SY='I';  M=-29,-67,-66,-61,  5,-31, 25, 43,-24,-17,-41,-58,-67,-12,  6,  2,-19, 27,-63, 17; D=-9;
/I:         I=-9; MD=-22;
/M: SY='P';  M=-66, 20,-66, 11,-21,-79,-68,-63,  2,-22,-63,-69, 44,-60,  4,-30,-26, -2,-79,-14; D=-9;
/I:         I=-9; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='D';  M=-26, -1, 46,-55,-86,  0,-11,-78,-65,-82,-76,-55, 45,-16,-72, -8,-14,-37,-92,-77; D=-9;
/I:         I=-9; DM=-22;
/M: SY='S';  M= 17,-66, 11, -6,-62, 13, 15,-26, -6,-36,-57,-48,  1,-49,-21, 29,-17,-30,-69, 10; D=-9;
/I:         I=-9; DM=-22;
/M: SY='F';  M=-28,-63,-28,-52, 40,-62,  0, -4,  8,  4,-42, -2,  9, 20,-50,  1, 10,  6,-55, 29; D=-9;
/I:         I=-9; DM=-22;
/M: SY='D';  M=-51,-65, 37, 14, 13,  5,  7,-63,-15,-36,-55, 16,-59, 10, 35, -8, 25,-60,-66, -8; D=-9;
/I:         I=-9; DM=-22;
/M: SY='G';  M=-22,-63,  4,  6,-65, 64,-53,-21,-47,-37,-56, 10,-12,-46,  5, 24,-22,-30,-68,-60; D=-9;
/I:         I=-9; DM=-22;
/M: SY='C';  M=-14, 59,  3,-17, 20,-24, 47,  1,-20,-49,-45, 26,-16, 35, 11,-45,-16, -1,-61, 14;
/M: SY='W';  M=-49,-61,-51,-47,-15,-58,-48,-43, 23, 25,  0, 34,-61, -6, 45,  7,  3, -6, 73,-43;
/M: SY='W';  M=  2,-62,-67,-62, 47,-63,  0,-35,-59, 39,-33,-63,-68,-56,-58,-22,-51, -7, 88, 68;
/M: SY='V';  M=-27,-58,-63,-56,-43,-30,-61, 40,-12, 20,  6,-57,-15,  9,-21,  0,-42, 58,-66,-48;
/M: SY='D';  M=-54,  4,112,-20,-75,-18,-42,-74,-43,-72,-70,-24,-55,-43,-52,-43,-45,-70,-89,-59;
/M: SY='G';  M=-36,-64,-51,-61,-70, 97,-58,-77,-24,-73,-62,-37,-55,-53,-61, -8,-54,-71,-61,-64;
/M: SY='G';  M= 23,-60,-16,-55,-63, 80,-53,-69,-53,-67,-59, -7,-55,-49,-59, 28,-46,-61,-61, -4;
/M: SY='V';  M=-49,-58,-67,-25, -5,-72,-58, 38,-61, 46,-25,-65,-66,-58,-62,-57,-16, 54,-56, 32;
/I:         I=-45; MI=0; MD=-115; IM=0; DM=-115;
/M: SY='V';  M= 21,-55, -4, -3,-47,-55,-54,-11,-49, 24, -5,-12,-58,-47, -7, 28, 16, 32, 21,-49;
/M: SY='N';  M= 20,-56, 50,-15,-57,-46,-42,-50,-44, -3, 37, 70,-57,-42,-50, 12, -2,-25,-74,-54;
/M: SY='N';  M= -9,  5, 31,-43,-63,-14,-39,-25,-40,-62,  0, 95,  2,-42,-18,-14, -8,-29,-78,-58;
/M: SY='N';  M=-52,-60,  5,-20, 21,-59,-45, 35,-48, 31,-35, 60,-62, 12,-18,-47, -4,-36,-58, 15;
/M: SY='P';  M=-54,-79,-54,-43,-74,-56,-57,-61,-50,-72,-58,-61,124,-54,-63,-51,-46,-67,-67,-71;
/M: SY='I';  M=-16,  7,-60,-58, 21,-33, -1, 50,-24,  5, 35,-51,-59,-54,-57,  9, 41, 10,-62,-42;
/M: SY='S';  M= 24,-58, 13,-15,-49,-23, 30, -5, -6, 12,-43, 17,-57,-15,-49, 34,  6,-45, 16, 13;
/M: SY='F';  M= 19,  8, 17, 18, 30,-59,-51, -5,-22, 27,-38,-13, 15, -9,-27,-48,-46,  2,-58, -6;
/M: SY='W';  M= 40,  5,-63,-24, 31,-56,-58, 10,-56, 29, 32,-57,-61,-53,-59, -1,-18,  9, 51,-39;
/M: SY='I';  M= -2, -9,  8,-47,-14,-27,  2, 44, 17,-26,  7,  4,-14,-45, 34,-12,  1,-17, 25,-46;
/I:         E1=0; IE=-380; DE=-380;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 170 in 170 different sequences
Number of true positive hits 170 in 170 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] PNPLA
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
170 sequences

463L_IIV6   (Q91F63), CAPE_ECOLX  (Q6XGD4), CAPV_ECOTW  (P0DTE9), 
CAPV_PSEU5  (P0DX85), CAPV_VIBCH  (Q9KVG8), COTR_BACSU  (O06996), 
LPAI_ARATH  (F4HX15), NTE1_ASPCL  (A1C9L6), NTE1_ASPFU  (Q4WA15), 
NTE1_ASPNC  (A2R350), NTE1_ASPOR  (Q2UDH2), NTE1_ASPTN  (Q0CNC7), 
NTE1_CANAL  (Q5A368), NTE1_CANGA  (Q6FKJ1), NTE1_CHAGB  (Q2H0D3), 
NTE1_COCIM  (Q1DLC7), NTE1_CRYNB  (P0CP37), NTE1_CRYNJ  (P0CP36), 
NTE1_DEBHA  (Q6BQK9), NTE1_EMENI  (Q5BAE9), NTE1_ENCCU  (Q8SVN8), 
NTE1_EREGS  (Q756Z0), NTE1_KLULA  (Q6CWC2), NTE1_LODEL  (A5E708), 
NTE1_NEOFI  (A1D9Y2), NTE1_NEUCR  (Q7S8J1), NTE1_PHANO  (Q0UJ42), 
NTE1_PICGU  (A5DHA3), NTE1_PICST  (A3LYZ4), NTE1_PYRO7  (A4QVZ8), 
NTE1_SCHPO  (Q9USJ4), NTE1_USTMA  (Q4PF83), NTE1_YARLI  (Q6CF18), 
NTE1_YEAST  (Q04958), PAT01_SOLTU (Q2MY50), PAT02_SOLTU (Q2MY60), 
PAT03_SOLTU (Q2MY48), PAT04_SOLTU (Q2MY42), PAT05_SOLTU (Q3YJT5), 
PAT06_SOLTU (Q2MY45), PAT07_SOLTU (Q2MY44), PAT08_SOLTU (Q2MY43), 
PAT0_SOLTU  (P07745), PAT10_SOLTU (Q2MY41), PAT11_SOLTU (Q2MY40), 
PAT12_SOLTU (Q2MY39), PAT13_SOLTU (Q2MY38), PAT14_SOLTU (Q2MY37), 
PAT15_SOLTU (Q2MY36), PAT16_SOLTU (Q41487), PAT17_SOLCD (Q8LPW4), 
PATA2_SOLTU (Q2MY59), PATA3_SOLTU (Q2MY58), PATB1_SOLTU (P15476), 
PATB2_SOLTU (P15477), PATD2_SOLTU (Q2MY56), PATD3_SOLTU (Q2MY55), 
PATJ1_SOLTU (Q2MY54), PATM1_SOLTU (P11768), PATM2_SOLTU (Q2MY52), 
PATM3_SOLTU (Q2MY51), PATT5_SOLTU (P15478), PLA2_CAEEL  (Q20500), 
PLP1_ARATH  (O23179), PLP1_ORYSI  (B8AQW7), PLP1_ORYSJ  (Q84QY3), 
PLP1_PLAFO  (W7K139), PLP2_ARATH  (O48723), PLP2_ORYSI  (A2YW91), 
PLP2_ORYSJ  (Q6ZJD3), PLP3_ARATH  (O23181), PLP3_ORYSI  (B8B7E7), 
PLP3_ORYSJ  (Q8H5D4), PLP4_ARATH  (Q9FIY1), PLP5_ARATH  (O23180), 
PLP6_ARATH  (O80959), PLP7_ARATH  (Q9SV43), PLP8_ARATH  (Q8H133), 
PLP9_ARATH  (Q93ZQ3), PLPL1_HUMAN (Q8N8W4), PLPL1_MOUSE (Q3V1D5), 
PLPL2_BOVIN (Q2KI18), PLPL2_CAEEL (Q11186), PLPL2_HUMAN (Q96AD5), 
PLPL2_MOUSE (Q8BJ56), PLPL2_RAT   (P0C548), PLPL3_HUMAN (Q9NST1), 
PLPL3_MOUSE (Q91WW7), PLPL4_HUMAN (P41247), PLPL5_HUMAN (Q7Z6Z6), 
PLPL5_MOUSE (Q32LZ8), PLPL6_CAEEL (Q21534), PLPL6_HUMAN (Q8IY17), 
PLPL6_MOUSE (Q3TRM4), PLPL6_PONAB (Q5RDS0), PLPL7_CAEEL (Q02331), 
PLPL7_HUMAN (Q6ZV29), PLPL7_MOUSE (A2AJ88), PLPL7_RAT   (Q5BK26), 
PLPL8_HUMAN (Q9NP80), PLPL8_MOUSE (Q8K1N1), PLPL8_RABIT (Q5XTS1), 
PLPL8_RAT   (D3ZRC4), PLPL9_CRIGR (A0A3L7I2I8), PLPL9_HUMAN (O60733), 
PLPL9_MOUSE (P97819), PLPL9_RAT   (P97570), PLPL_ASPCL  (A1CRG6), 
PLPL_ASPFU  (Q4WJS4), PLPL_ASPNC  (A2Q8F7), PLPL_ASPOR  (Q2UKE6), 
PLPL_ASPTN  (Q0CUP0), PLPL_CANAL  (Q5AM72), PLPL_CHAGB  (Q2HA54), 
PLPL_COCIM  (Q1DXR6), PLPL_CRYNB  (P0CP53), PLPL_CRYNJ  (P0CP52), 
PLPL_DEBHA  (Q6BXC8), PLPL_EMENI  (Q5BGC2), PLPL_LODEL  (A5DUA8), 
PLPL_NEOFI  (A1D4C8), PLPL_NEUCR  (P0C584), PLPL_PHANO  (Q0V4Z6), 
PLPL_PICGU  (A5DIR3), PLPL_PYRO3  (P0CT18), PLPL_PYRO7  (A4R8V2), 
PLPL_YARLI  (Q6C8W4), PT1K2_SOLTU (Q3YJT4), PT2K1_SOLTU (Q3YJT3), 
PT2K2_SOLTU (Q3YJT2), PT2K3_SOLTU (Q42502), PT2K4_SOLTU (Q3YJT0), 
PT3K1_SOLTU (Q3YJS9), RSSA_ECOLI  (P0AFR0), RSSA_SHIFL  (P0AFR1), 
SDP1L_ARATH (Q9M1I6), SDP1_ARATH  (Q9LZA6), SUHR_RHIME  (P15715), 
SWS_DROAN   (B3MRI9), SWS_DROER   (B3NY03), SWS_DROGR   (B4JLX2), 
SWS_DROME   (Q9U969), SWS_DROMO   (B4L535), SWS_DROPE   (B4H3U8), 
SWS_DROPS   (B5DKS8), SWS_DROSE   (B4IL64), SWS_DROVI   (B4M709), 
SWS_DROWI   (B4N1W9), SWS_DROYA   (B4Q0P3), TEG_PRIM2   (P30420), 
TGL3_SCHPO  (Q9Y7P3), TGL3_YEAST  (P40308), TGL4_SCHPO  (O14115), 
TGL4_YEAST  (P36165), TGL5_SCHPO  (Q9Y827), TGL5_YEAST  (Q12043), 
Y1063_MYCTO (P9WIY8), Y1063_MYCTU (P9WIY9), Y1092_MYCBO (P67099), 
Y2565_MYCTO (P9WIY6), Y2565_MYCTU (P9WIY7), Y2594_MYCBO (P0A643), 
Y3479_MYCTU (O06342), Y4II_SINFN  (P55492), YJJU_ECOLI  (P39407), 
YL446_MIMIV (Q5UQP2), YL620_MIMIV (Q5UR65), YLBK_BACSU  (O34731), 
YQHO_BACSU  (P54513), YR571_MIMIV (Q5UR46)
» more

PDB
[Detailed view]
5 PDB

1OXW; 4PK9; 4PKA; 4PKB; 6AUN