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PROSITE entry PS51650


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General information about the entry

Entry name [info] C2_DOCK
Accession [info] PS51650
Entry type [info] MATRIX
Date [info] 01-JUL-2012 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51650
Associated ProRule [info] PRU00983

Name and characterization of the entry

Description [info] C2 DOCK-type domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=175;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=170;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4855449; R2=0.0083916; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=29089.3359375; R2=4.9380307; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=896; H_SCORE=33514; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=479; H_SCORE=31455; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-45; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='R';  M=-143, -46, -77, -38, -33, -95, -47,  -4,   8, -34,-139,  -4,-153,   4,  86,   7,  -1, -14,-154,  -1;
/M: SY='N';  M=-142,-151, -44,-136, -70, -79,  78,-158,-131,-160,-147, 116,-153, -32, -68,   3, -80,-159,-175,-143;
/M: SY='D';  M= -93,  -4,  72,  23, -63,-149,  38, -87,  -6,  -4, -42,  18, -22,  30, -49, -24,  -2, -22,-167,-144;
/M: SY='L';  M= -99,  -8,-165,-159,  -2,-166,-151,  45,-158,  73,  44,-161,-162,-153,-156,-155,-142,   1,-151, -28;
/M: SY='Y';  M=-151,-159,-153,-155,  49,-159, -34, -52,-148, -50,-130, -61,-163,-145,-146, -53, -40, -57,-114, 127;
/M: SY='I';  M=-142, -42,-165,-160,  28,-167, -38,  74,-157,   7, -38,-157,-159, -64,-158,-151, -68,  65,-154,-133;
/M: SY='Y';  M= -63, -39,-142, -51, -77, -56, -14,-142,  -4, -57,-137, -21,-152, -18,   0,   0,  65, -70,-134,  99;
/M: SY='P';  M= -80,-159,-157,-148, -66, -96,-152,  24,-151,  54, -36,-158,  95,-150,-157,-150, -68, -24,-156,-145;
/M: SY='Q';  M= -55,  -9,  17,  23,-148, -83, -57, -12,  32,   9, -52,  13,-150,  42,  17, -19, -13, -11,  35,-143;
/M: SY='S';  M= -39, -33, -48,  33, -36, -50,  32, -42,   8,-104,  -5, -29,-146,  39,   0,  62,   9, -63,-159, -36;
/M: SY='G';  M=  26,  -7,-154, -56, -54,  48,-153,  19,-151,  34, -53,-146, -20,-149,-155, -79, -21,  22,-156,-145;
/M: SY='N';  M= -27, -30,  31,  33, -47,-143, -18, -59,  40,-154, -41,  65,-146,   2,  -7,  13,   9, -67,-163,-146;
/M: SY='F';  M=-149, -54,-162,-158,  89, -81,-146,  31, -60,  34, -50, -65,-162,-155, -58, -51, -69, -22,-133,  43;
/I:         I=-9; MD=-23;
/M: SY='S';  M= -25,-157,  43,  21, -73,  -2, -22,-158,  16,-106, -42, -34,  20, -35, -24,  51,   0, -87,-164, -46; D=-9;
/I:         I=-9; MD=-23;
/M: SY='K';  M= -25,-157, -50,-135, -67, -25, -14,-157,  62, -65,-148,  25, -22,  14,  15,  44, -46, -78,-159, -16; D=-9;
/I:         I=-9; MD=-23;
/M: SY='Q';  M= -70, -21,  -1, -10,  -2,  23, -22, -77,  12, -57,-148, -62,   8,  54,  27, -34,   3, -53,-160, -48; D=-9;
/I:         I=-9; MD=-23;
/M: SY='K';  M= -15, -55, -44, -51, -47,  15, -15,-103,  52, -73, -42,   2,  10, -27,  14,   3, -11,-159,-166,-155; D=-9;
/I:         I=-9; MD=-23;
/M: SY='K';  M= -81, -23,-159, -69, -44,   7, -21, -37,  42,   3, -39, -34, -79, -38, -44, -47,  20, -66, -13, -61; D=-9;
/I:         I=-9; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='S';  M=   3,  21,-158,-157, -28, -63, -69, -76, -55, -43, -50, -19, -42, -20, -24,  41,  29,  -4,-175,-158; D=-9;
/I:         I=-9; DM=-23;
/M: SY='K';  M= -20,-157,-142, -74,-162, -91, -16,-157,  66,-105,-150,   0, -17,  22,  -4,  45,  16, -52,-164,-151; D=-9;
/I:         I=-9; DM=-23;
/M: SY='A';  M=  53, -40,   9, -34, -67,   2,  32,-154,  -3, -49,-147,   0, -13,  10, -22, -13, -31, -94, -19, -12; D=-9;
/I:         I=-9; DM=-23;
/M: SY='R';  M=-143, -20,-139, -43,-157, -25, -12,-160,  61,-155, -18, -16, -53,  11,  90, -12, -68,-155,-157,-144;
/M: SY='N';  M= -79,-149, -41,-138, -41, -11, -40, -90, -21,-160, -45, 118, -67,-132,-137,  -4, -16,-155,-170,-149;
/M: SY='I';  M=-142,-153,-163,-160,   3, -89,-158,  83,-156,  17, -14, -40,-157, -57,-158,-151, -70,  51,-153, -27;
/M: SY='Q';  M=  17,  -2,-138,  50,  12, -75,-141, -36, -75,  -1, -22, -59,-149,  59, -44, -14,   3,  14,-154, -30;
/M: SY='V';  M= -11,  63,-161,-157, -63,-160,-159,  45,-154,  -3,  19, -65, -63,-154,-156,-146,-135,  78,-161, -57;
/M: SY='T';  M= -25,  11, -67,   6, -76, -88,  -2, -20,  32, -71,   4, -66, -65,   2,  45,  -2,  60,  -4,-160,-143;
/M: SY='V';  M=  -4,  -1,-161,-156, -25, -81,-156,  48,-153, -27,  64,-155, -40,-152,-155,-146, -70,  76,-157, -28;
/M: SY='E';  M= -63,  40,-129,  69,-150, -68,  -3, -56,   2, -43, -58, -66,-145,  56,   0,  27,  -6, -93, -45,  15;
/M: SY='V';  M= -65,-149,-162,-156,  48,-162,-150,  11,-154,  48,   9,-157,-160,-153, -71, -56, -84,  62,-145,  24;
/M: SY='R';  M=-144,  33,-148, -84,-140, -92, -25,  -7,  16,  -1,  41, -71,-155, -34,  85, -75, -42,  -2,  -6,  19;
/M: SY='D';  M= -10, -19,  61,  27,-153, -14, -47,-152,  24, -35, -44,  48, -41, -32,  -3,  -3, -28, -68,-161,  -3;
/M: SY='S';  M=   1, -53,  31,  25,-155,  10, -64, -79,  -9, -52,-146,  47, -62, -16, -20,  49,   4, -45,-163,-148;
/M: SY='D';  M= -44,-157,  91,  21, -58, -35, -23, -78,  -5, -42,-150,   4,   5,  14, -76,  -2, -12, -93,-167,-147;
/I:         I=-20; MD=-51;
/M: SY='G';  M= -47,-156,  36,  19,-154,  55, -41, -48, -10, -26, -24, -19,-148,   7, -48,  10,  10, -64,  22, -68; D=-20;
/I:         I=-20; MD=-51;
/M: SY='N';  M= -77,-158,  30,  32, -83, -11,  -8, -64,  16, -26, -29,  38, -24,   4,   0,  16,   0, -76,-166,-150; D=-20;
/I:         I=-20; MD=-51;
/M: SY='T';  M= -63,-170,   9, -53,  -1, -41,-161,  -5, -18,  -6, -57, -24, -63, -68,  -4,   3,  15, -35,-174,-157; D=-20;
/I:         I=-20; MI=0; MD=-51; IM=0; DM=-51;
/M: SY='S';  M=  13, -26, -30,  16, -26, -58,-153,   8, -74,-100,-148, -18,  22, -17,-153,  40, -23,   3,-165, -30; D=-20;
/I:         I=-20; DM=-51;
/M: SY='I';  M= -97, -49,  16,  -1,-142, -31, -58,  29,  27,  21,   2,  -6,  19,  10, -15, -22,  -8,  10,-158,-142;
/M: SY='P';  M=   3, -21, -37,  29,-154,  -5,   9,   7,   0,-150,-143, -33,  72,   5,   1,  23, -55, -62,-157, -28;
/M: SY='N';  M= -42, -56,  14, -17, -73,   7, -21,   6, -18,  44,  38,  46, -67, -24, -38,  -9, -79, -47, -30, -56;
/M: SY='C';  M=   8,  59, -15,   5, -36, -37,-142, -57,  43, -66,  -9,  17,  56,  -4, -14, -50, -60, -13, -28, -24;
/M: SY='C';  M=  17,  85, -58, -83,   6,-152,-151,  45, -74,  10, -17, -85, -36, -65, -45,  17,-135,  19,-155, -30;
/M: SY='I';  M= -31,  10,-153, -84,  50, -95, -60,  65, -81,   3,  -6,  -9, -18, -41, -75,  27, -77, -11,  -1,   0;
/M: SY='Y';  M= -41,-154, -60,-147,  55,-154,  35, -27, -71, -13,  11, -30,  -1, -29,   0, -64,  14, -20, -27,  90;
/I:         I=-9; MD=-22;
/M: SY='G';  M= -42,-156,   3, -41, -71,  72,  -8, -62, -49, -71,-151,  16,  42,-141, -52,  22, -14,-155,-160,-153; D=-9;
/I:         I=-9; MD=-22;
/M: SY='R';  M=  24, -47, -79, -26,-161, -35, -36, -57,  32,-157, -54,   8,  18, -26,  54,  27, -44, -72,-163,-152; D=-9;
/I:         I=-9; MD=-22;
/M: SY='P';  M= -75,-173, -49,-160,  21, -29, -56, -17, -39, -55,   5,-158,  35, -30, -31,  25,  -1, -73, -17, -39; D=-9;
/I:         I=-9; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='G';  M= -65,  -3,  14, -31, -82,  54,-148,-165, -11, -64,-157,  36, -15,   0, -20,   5, -19, -89,-168,-159; D=-9;
/I:         I=-9; DM=-22;
/M: SY='P';  M= -20,-155,  20,  29, -69,   9, -46, -35,  -1, -51, -53,  12,  56,  17, -33,  37, -39, -43,-159,-148;
/M: SY='P';  M= -31, -53, -45,  36, -68, -66,-138, -43,  13,   5,-139,  39,  43,  21,  -3,  27, -16, -39, -22, -53;
/M: SY='F';  M= -28, -39,-149, -44,  44, -14,  17, -15, -21,  20,  35,  -6,  41, -39,  -5, -16, -34, -23,  32,   1;
/M: SY='V';  M= -10,  33, -13,  -6,   6, -95, -47, -30, -24, -10,   5,  -6, -25,   2,  -8,   4,  31,  44,-158, -69;
/M: SY='T';  M= -42, -25,   4,   6, -50, -17,  -1, -62,   2, -46,-143,   8,   4,   0, -21,  51,  55,-143,-156,  11;
/M: SY='E';  M= -49, -36,  -3,  50, -28, -69,  29, -25, -21, -48, -57,-134,-146,  35, -16,  48,  -1,  -2,  22,  15;
/M: SY='Y';  M=  37, -35, -50, -43,  44, -46,  15, -50, -68, -43, -60, -27,-153, -19, -36,   3,  -2, -21,  50,  76;
/M: SY='Y';  M= -36,  17, -28, -13,  40, -49,  21, -28,   7, -80,-137, -20,-151, -14,  22,  22,  13,  -3,  43,  48;
/M: SY='S';  M= -15,  30, -81, -72,  -8, -77,-144, -56, -79,-148,-144, -60, -75,-136,-144,  83,  67, -71,  48, -47;
/M: SY='S';  M=  12,  17, -88, -73,  -2, -94,  -9,  -9, -52, -22,   6,-137, -20,  19,  -2,  48,  44,  12,-156, -29;
/M: SY='V';  M= -26,  47,-155,-152,-137, -84,-158,  25,-150, -39,-126,-148, -69,-151,-154,  18,  18,  84,-164,-143;
/M: SY='Y';  M=  -7, -10, -81, -81,  18, -55,  28, -40,-144,  29,-128, -22,-154,  -8, -69,  11,  23,  12, -12,  69;
/M: SY='Y';  M= -22, -56, -44,-146, -48, -91,  72, -22, -87, -36,-131, -31,  -3,-139,-143,   7, -92,   4, -27, 108;
/M: SY='H';  M= -25,-156, -53, -49,-147, -27, 127, -84, -45, -98, -54,  32, -39,  24, -26, -36, -14, -43,-166,  -3;
/M: SY='N';  M= -28, -58,   1,  44,-152, -48, -37, -58, -41, -57, -24,  76, -75,  18, -84,  29,  10,   7,-163, -71;
/M: SY='K';  M= -29,-154,   1,  -7,-154, -81, -15, -63,  70, -34, -41,  46, -42,  19,  39, -18,   2,-148,-158,-144;
/M: SY='N';  M= -34,  10, -17, -57,-151, -11,   6, -30,   8, -56, -21,  57,-147,  44,   1,  29,  46, -46,-161, -64;
/M: SY='P';  M= -28, -15, -17, -36, -42, -27,-147, -80,-141,-154,  -6, -67, 118, -28,-151, -48, -38, -27,-158,-155;
/M: SY='Q';  M= -14, -33,  -1,  15, -27, -91,  34, -25,  22, -78, -22,  11, -40,  54,  19, -14,  19,   6,-157, -29;
/M: SY='W';  M=-154,-160,-170,-160,  98,-158,-154,-135,-154, -20, -39, -64,-162,-158,-154,-156,-153, -75, 143,  15;
/M: SY='N';  M= -65,   0,   3, -38,  -7,   0,  47, -40, -50, -18,  37,  65,-151, -22, -65,  19, -15, -55, -23,  50;
/M: SY='D';  M=-142,-160,  92,  83,-163, -93, -19,-161,-127, -78, -43,-124,-141,  20,-135, -78, -75,-157,-168,-149;
/M: SY='E';  M=-137, -45, -63,  90,-150,-152,-138, -58,-129, -29,  -5,-135, -48,  -7,-137, -37,  69, -34, -30, -56;
/M: SY='F';  M= -33,-151,-165,-160,  79,-163,-156,  73,-156,  -3,  -5,-156,-158,-157,-157,-150,-139,  38, -35,-121;
/M: SY='K';  M=-142, -38,-137, -81,-155,-151, -40, -23, 103,-151, -21,-130,-145, -54,  46, -80, -25, -62,-153,-143;
/M: SY='I';  M=  -6, -16,-162,-156, -38,-161,-156,  68, -74,  40,  29,-155,-156,-151,-155,-148, -74,  52,-155,-136;
/M: SY='Q';  M=  13, -29,  22,  23, -81, -56,  -1, -41,  21,-103,-144,  21, -23,  61,  13,  23, -23, -70,   6,-144;
/M: SY='L';  M=-144,-150,-162,-156,-123,-165,-151,  49, -53,  81,  -7, -66,-160,-150,-154, -83,-140,  10,-152,-134;
/M: SY='P';  M= -52,-167, -29, -43,-163, -86,-148,-151,-141, -93,-148, -79, 126, -58, -77, -57, -66, -63,-159,-160;
/M: SY='P';  M=  15,  11, -80,  -6,  18, -67,  -4,  19, -86,  21,  -2, -24,  35, -17,-148, -10,  24,  -4,-152, -24;
/M: SY='D';  M= -84, -26,  48,  39, -83,-147,  24,  -5,  14, -69,-143,  32,  41,  36, -11,  -8, -44, -34,-162, -71;
/M: SY='L';  M= -52,-151,  16, -15,-133, -78, -15,  21, -29,  60,   5, -59, -47,   8, -90, -10,  -5,   1, -33, -62;
/I:         I=-12; MD=-30;
/M: SY='F';  M= -97,-153, -14, -14,  47, -37,  30, -31, -42, -45,  13,  33,  17,  -6, -31,  -8,  42,   2,-153, -18; D=-12;
/I:         I=-12; MI=0; MD=-30; IM=0; DM=-30;
/M: SY='P';  M= -26, -50,  49,  32,-155, -57, -16,-152,  23, -54,-146,   2,  54,  25,  -5,  -4,   5, -60,-160, -19;
/M: SY='N';  M= -64, -57,  20,   2,-156,  30,   3, -85,  46,-102, -58,  49,-146,  14,  25,  19, -23,-153, -34, -57;
/M: SY='H';  M=  16,  35, -15,-138, -40, -82, 109, -29, -81, -21, -49, -38, -65, -14,-140,  28, -19, -61, -13,  38;
/M: SY='H';  M= -60,-159,-135, -47,-141, -60, 145, -22,-137, -86,-133,-126,-150, -31, -44, -48,-145, -84,-167,  25;
/M: SY='L';  M= -89,-149,-164,-157,   6,-165,-151,  38,-157,  81, -59,-160,-161, -65,-155,-154,-140,  20,-150,-131;
/M: SY='L';  M=-144, -11,-156, -76,  44,-161, -38, -23, -22,  63,-119, -39,-160, -55,  36,-149,-140,  30,-147, -28;
/M: SY='F';  M=-151,-151,-166,-160, 114,-162,-148,  21,-156, -14,  45,-156, -63,-161, -68,-153,-144, -28,-128,-106;
/M: SY='T';  M= -89,-146, -65,  23, -41, -91, -52, -60, -35, -29,  26, -64,-144, -61, -38,  38,  84,   6,-158,  -2;
/M: SY='F';  M=-148,  -4,-165,-160, 103,-163,-150,  34, -75,   9,-123,-156,-162,-161,-155,-152,-142,  27,-132, -14;
/M: SY='Y';  M=  -7,-156, -73,-140,  34,-151, -29, -76,   3, -53,-134, -69,-155,  12,  57,  -6, -45, -24,-130,  94;
/M: SY='H';  M= -32,-157,  36, -32, -60, -41, 135,-161,-135,-151,-139,  28, -68, -34, -68, -18,-141, -93,-175,-126;
/M: SY='C';  M=  13,  67,-155,-149,-139, -56,-152,  39, -15, -35,  -5,-148,-155, -69,  33, -60, -67,  62,-160, -51;
/M: SY='S';  M= -32,   5,   5, -45, -46, -52,  41, -38, -30, -67,-143,  -7,  11,  -7, -39,  80,  -1, -17,-162,-143;
/I:         I=-4; MD=-10;
/M: SY='C';  M=   4,  90, -53, -17, -64, -80,   0, -32, -32, -50,-139, -34, -41, -55, -40,  34,  16,  36,-165, -47; D=-4;
/I:         I=-4; MD=-10;
/M: SY='K';  M= -33, -65,  31,  -1, -92, -39, -16, -60,  55, -64,  -2,  10, -38,  46,  25,  -9, -21, -91,-160, -64; D=-4;
/I:         I=-4; MD=-10;
/M: SY='E';  M= -80,-161,  22,  43,-160, -25,   0, -37,  28, -77,   3,  18,  -4,   8, -26,  -3,  10, -54,-166, -59; D=-4;
/I:         I=-4; MD=-10;
/M: SY='K';  M= -14,-159,  -4, -14,-165,  -4,-145, -91,  45,-106,-154,  36, -34,   2, -23,  39,  -8, -82,-168,-156; D=-4;
/I:         I=-4; MD=-10;
/M: SY='K';  M= -35,-165, -43, -38, -72, -10, -61, -40,  56, -28, -14, -41, -37,  12, -25,  -3,   6, -54,-166, -53; D=-4;
/I:         I=-4; MD=-10;
/M: SY='K';  M= -47,-175, -35,   7,-176, -19, -39, -40,  40,-115,-166,   8,   0, -26, -91,  15, -56,-109,-179, -85; D=-4;
/I:         I=-4; MD=-10;
/M: SY='K';  M=  -5,-173, -19, -75, -68, -35, -58, -87,  30, -39,-164, -39, -60, -45,-155,   5,  24, -66, -19,-167; D=-4;
/I:         I=-4; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='D';  M= -46,-176,  62,  28,-180, -42, -56, -93, -19,-103, -50,   4,-165, -16, -31, -40, -43, -83,-187,-168; D=-4;
/I:         I=-4; DM=-10;
/M: SY='S';  M= -37,-166, -35, -15, -35, -27,-151, -89,  27, -46,-155,  15,  27,  25, -22,  32, -63, -35,-169,-157; D=-4;
/I:         I=-4; DM=-10;
/M: SY='S';  M=  -6, -65,   3,  11, -67, -73, -47, -30, -15, -35, -21,  -6,  -6,   8,   4,  22, -16,  17,-169,-153; D=-4;
/I:         I=-4; DM=-10;
/M: SY='E';  M=-143, -40,   2,  72, -44, -52,-141, -52,  -9, -33,  -5, -19, -24,   7,  28, -29,  12, -36, -15,-148; D=-4;
/I:         I=-4; DM=-10;
/M: SY='T';  M= -26,-154, -17,  15,  13, -21, -47, -29,  38, -42,  -3,  -7, -64,  30,  -6,  -5,  41, -30,-156, -52; D=-4;
/I:         I=-4; DM=-10;
/M: SY='P';  M= -55,  10, -41, -29, -37, -86,  -4,  -6,   1,  18,-133, -22,  78, -26, -12, -44,   0,  10,-156, -13; D=-4;
/I:         I=-4; DM=-10;
/M: SY='F';  M= -65, -42,-160, -79,  76,-161, -23,  60,-153,  16, -33,-152,-157, -27,-153, -43, -19,  39,-142,-122;
/M: SY='G';  M=  49, -34,-145,-149, -21,  87, -50, -98,-145, -74, -56,-134,-148,-143, -45, -53,-141,-100,-149,   2;
/M: SY='Y';  M=-147, -26, -48,-150,  70,-156,  32, -40, -45,   3,  40, -22,-158, -77, -69, -27, -45, -28,  14,  91;
/M: SY='A';  M=  74,  30,-143,-141,-153,  12,-145,-148,-141, -61,-143, -80, -84,-137,-146,  65,  -4,-138,-157, -66;
/M: SY='W';  M= -22, -39, -67, -73,  74,-153,  17, -17, -28,-133,-135, -76,-157,-147,-147, -11, -42, -11, 123,  67;
/M: SY='L';  M= -54,-150,-162,-154,   8,-162,-149,  28,-153,  70,  37,-157,-159, -38, -70, -89, -89,  29,  29, -15;
/M: SY='P';  M=-144,-165, -51, -34, -81,-148, -11, -91,  30,-112, -51, -19, 112, -30,  34,-140, -47,-155,-157,-152;
/M: SY='L';  M= -63, -36, -52,-155,  -9,-164,-149,  38,-156,  86, -16, -75,-160,-150,-154,-153,-141, -51,-150,-132;
/M: SY='M';  M= -20, -39,-154,-149,  33, -33, -56,  -5, -28,  28,  84, -26,-154, -17, -88, -13, -15,  -6,  63,  35;
/I:         I=-16; MI=0; MD=-40; IM=0; DM=-40;
/M: SY='K';  M= -54,-165,  14, -20,-166, -44,  14,-163,  47, -63, -20,  45, -12,  24, -12,  -3, -41, -84,-171,-155; D=-16;
/I:         I=-16; DM=-40;
/M: SY='D';  M= -28,-153,  55,  42,-153, -59,  28, -43,  28, -35, -45,  41,   6, -25, -20,   0,  12,-147,-162, -70;
/M: SY='D';  M= -28, -31,  65, -13, -76,  34,  12, -54,   3, -51,-146,  52,-146,  33, -23,  11, -72,-152,-162,-146;
/M: SY='G';  M= -45,-155, -36, -55,-155,  69,  22, -92,  15,-106,-144, -19,-148,  30,  51,  -6, -81,  -9, -35, -65;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='T';  M=  28,  -6, -41, -53, -48,-150, -16,   5,   8,  24, -11, -29,-151, -19, -44, -20,  51,  -5,-158, -30; D=-28;
/I:         I=-28; DM=-70;
/M: SY='F';  M=  -8, -31, -58, -72,  50, -93, -29,  20, -33,   9, -24, -12, -67,  10, -22,-136,  49,  28,-147,   5;
/M: SY='I';  M= -89, -33, -29, -52, -32,-158,-151,  68,-148,  40,  20, -23, -62, -38, -62, -21,   9,  31, -31,-135;
/M: SY='Q';  M=   8, -14, -19,   4, -66,   3, -20, -48,  19, -47,-140, -11,  36,  53,  16,   9,   8, -15,-157,-145;
/M: SY='D';  M= -89,-155,  93,  24,-160,  -6, -49, -33,  -3, -92,-152,  52, -45, -15,-136,  10,-133,-153,-169,-148;
/M: SY='G';  M= -40, -59,  21,  -1,   3,  80,   2, -70, -21, -45, -35, -80,-147,   2, -69,   4, -54,-151,-152, -35;
/M: SY='E';  M= -32, -10,  31,  37,-145, -62,  20,  -7,  -9, -45, -28,  -5,   8,  30, -32,  12,  13,   7,  11,  10;
/M: SY='H';  M= -75,-155, -49, -46,  -4,-152, 114,  -3, -17,  16, -13, -18,-152,  12, -88, -27, -48, -38,-149,  54;
/M: SY='P';  M= -88,-153,  38,  33, -30, -68, -31,  -5,  -5, -86, -22,  10,  50,   4, -43,  23,  40, -25,  -2,-144;
/M: SY='L';  M=-141, -17,-158,-152,  -9,-161,-149,  32, -16,  68,  -6, -63, -42, -53,-149, -72, -28,  40,-151, -34;
/M: SY='P';  M=  13, -28, -21, -77,  16, -44, -10, -20, -26,   4,  -9, -28,  62,  12, -48,  19, -19,  -5,-149,  17;
/M: SY='V';  M=  -5,-148, -89, -73, -37, -44,-151,  45, -64,  35,  15,-148,-153, -16, -84,  10, -35,  59,-155,-137;
/M: SY='Y';  M=  -8, -20, -15,  13,  26,-100,  58, -25, -93, -24, -31,   9, -21,-136,-142,   8,  -3, -40, -35,  87;
/M: SY='K';  M=  -7,-153, -81, -27,-141, -87, -17, -14,  81,  12,-133, -17,  -9, -48,  -9, -28, -13, -29,-148,  27;
/M: SY='Y';  M=  -6,  37,  19,  -3, -40,   8, -12,  -5, -59, -13, -25,  -1,  30, -72, -13, -30,   0,   1,  -3,  49;
/M: SY='D';  M= -27, -67,  65,   7, -53, -31,  15, -45, -14, -14, -13,  -8,  58,  16, -89,  19, -21, -62,-161,-145;
/M: SY='P';  M= -81,-153,  16,  19,-152,  18,  15, -56,  20, -42, -58,  27,  34,   0, -14,  28,  15, -13,-159, -66;
/M: SY='Y';  M= -20,-153,  -7, -80, -13, -72,  15, -37,  25,  -5, -46,  20,  44, -10, -30,  24,  -4, -13, -16,  52;
/M: SY='P';  M= -10,-152,  15,  -7, -41, -32, -12, -33,  30,   8, -30,  -1,  31, -10, -14,   4,  19, -28, -40,  26;
/M: SY='S';  M= -13, -19,   3, -36, -17,  18, -68, -61,   6, -31,  24,  24,  -7,  13, -82,  44, -27, -26, -27,  44;
/I:         I=-18; MD=-45;
/M: SY='Y';  M= -25,-156,  13,  20,   7, -86,  20, -11, -14,  11, -32,   5, -15, -10, -61,  10,  -5, -31, -28,  37; D=-18;
/I:         I=-18; MD=-45;
/M: SY='P';  M= -17,-160,  -9,  -6, -12,-155, -53,  14, -13, -26, -25, -33,  36,  35,-147,  14,   0,  -8,-160,  -2; D=-18;
/I:         I=-18; MD=-45;
/M: SY='D';  M= -15, -58,  21, -14, -74, -31,  -3,  -1, -43, -25, -21,  -3,  21,  17, -33, -22,   6, -91,-166,   7; D=-18;
/I:         I=-18; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='S';  M=  12,-160,   2, -35,-154,-154, -66, -21,   9,  13,   5,  17, -38, -70,  -2,  27, -34, -85,-168, -54; D=-18;
/I:         I=-18; DM=-45;
/M: SY='S';  M=  -2, -56,  -6, -94,-157,  31,-148,-152,  19, -54, -13, -23, -73,-140, -23,  49,  30, -26, -25, -61; D=-18;
/I:         I=-18; DM=-45;
/M: SY='S';  M=  -9, -13, -65, -43,  12, -10, -18,  19,   7,  -7,-136, -22,  -5, -14,  -4,  21, -25,  10,-155, -13; D=-18;
/I:         I=-18; DM=-45;
/M: SY='Y';  M= -68,  22,  13, -87,  32,  -1,-128,-143,-139,-140, -25,  16,  12, -44,  -8,  22,-137,-145, -19, 103;
/M: SY='L';  M= -66,-150,  -3, -17,   9, -52,   7,  -1,  21,  56,  10,-142,-152, -33, -42,  -1,  -2,   2,-151, -52;
/M: SY='S';  M= -14,-150, -26,  22, -51,  -4,  18, -15,  25, -81, -58,  16, -21,  17, -22,  47,  19, -23,-155,  -6;
/M: SY='L';  M=   2, -16,   6, -34,  11, -22,-145,   8, -39,  52,  34, -23,-152, -67, -53, -58,  31, -16,-153,-135;
/I:         I=-10; MD=-24;
/M: SY='P';  M=  -8, -22, -43, -42, -79, -43, -20,-156,   4,-161,-151,  36,  88,   7, -71,  23,  -8, -88,-164,-155; D=-10;
/I:         I=-10; MD=-24;
/M: SY='W';  M=   2, -65, -78,   4, -81,  22, -48, -29, -21, -76, -64, -10,  24,-145,-152,  40, -25, -36,  41, -11; D=-10;
/I:         I=-10; MD=-24;
/M: SY='T';  M= -18,  -2,   4, -88, -29, -13,-159,-169,  -9, -85,-164,   9, -28, -39, -14,   4,  21,-101,  -7, -11; D=-10;
/I:         I=-10; MD=-24;
/M: SY='K';  M= -12, -59,-165, -40, -70, -67, -26,-163,  10, -30,-161,  -4,   5,-159,  -6, -46, -11, -18,-176,   8; D=-10;
/I:         I=-10; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='S';  M= -85,-172,  11,   4,-174, -32,  21,-168, -24,-169,  -3, -35,  19,  21,-155,  23,  15, -49,-181,-163; D=-10;
/I:         I=-10; DM=-24;
/M: SY='N';  M= -40,  20,   5, -11, -28, -12,-149, -80,   1,   5,  -2,  22, -39, -14,   6,  -3, -12, -46,-167, -66; D=-10;
/I:         I=-10; DM=-24;
/M: SY='M';  M= -24, -61, -13, -10,  -8, -12,  -6,   9,   9,   4,  26, -11, -27,   0, -19,  18,  10,  23,-153,  -8;
/M: SY='S';  M= -25,-151,  -4,  14, -66, -18, -19, -35,  42, -90, -53,  -8, -15,   7,  12,  49,  10,  10, -31,-143;
/M: SY='W';  M= -19,-154,   2, -27,  18,   1, -12, -50,  10,  16, -16, -33, -16,-138, -30,  26, -33, -43, 105,   8;
/M: SY='V';  M= -20, -27, -19, -36,  -3, -37, -37,  -4,   4,  26,  16, -63, -14,  -1, -69,   5,  -8,  38,  10,  23;
/M: SY='D';  M=  -8,-153,  56,  23, -40, -63, -53, -26,   5,  -4,  -5,  12, -11,  16,   9, -10,   9, -24,-157, -16;
/M: SY='N';  M= -20, -53, -11, -22,-149,  36,  -5, -23, -11, -25,-141,  56,  36,  -8,-141,  24,  10, -33,-157, -15;
/M: SY='H';  M= -53,  25, -16,  -9,-149,  26,  60, -17,  34, -13, -19,  -7,   3,   4, -37,  11,  20, -40,-159,-141;
/M: SY='K';  M= -20,-153,  -9, -19,-151, -60,-135, -15,  77, -29,  -2,  32,-146, -28,  41,  18, -49,-144,-156,-143;
/M: SY='P';  M=   5,  -9,  63,  19,-156,  -8, -18, -50, -89,-153,  -2,  15,  67, -23, -19,  -4, -11, -81,-162, -51;
/M: SY='T';  M= -45,   9,-146, -48,  -9, -94, -36,  27,  -3,  25,-127, -30,-150, -16, -27,  26,  49,  19,-151,  15;
/M: SY='F';  M= -66, -52, -59, -74,  89,-161,-146,  15, -73,  45, -15,-153,-159,-152,  -6,-149, -31,   7,-136, -13;
/M: SY='T';  M= -37, -56,  -9, -54, -16, -93,  18, -34,  44, -41, -30,  23,-145,   3,  17,  19,  60, -17,  -8, -56;
/M: SY='I';  M= -34,  20, -51,-152,  -2, -59,-154,  68, -50,   1, -47,-150, -87, -42, -29, -53, -49,  61,-153, -12;
/M: SY='R';  M= -32, -35,   5,   4, -46, -20, -24, -16,  14, -68,   1,  24, -27, -33,  54,  53, -27, -37,-158,-143;
/M: SY='T';  M= -31, -46,-145,-144,   5, -77, -47,   3, -86,  20,-129,-136,   1, -58,-147,  17,  86, -12,-152,  18;
/M: SY='R';  M= -78, -57, -16,  -9,   0,-149,  33, -50,  28,  17, -45,  34, -35,  27,  34,  -7,  -9, -15,   8,   6;
/M: SY='L';  M= -31, -50,-155,-150,  14, -47, -56,   4, -40,  65,   8,-149, -17,-146, -86,  14,   2,  18,-150, -58;
/M: SY='C';  M= -33, 105,  -8,-149, -21, -60, -21,  16, -54,   0, -53, -28,-157,-148, -33,   7, -82,  48,-160, -16;
/I:         E1=0; IE=-380; DE=-380;
» more

Post-processing [info]

PROMOTED_BY PS51651

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 24 in 24 different sequences
Number of true positive hits 24 in 24 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] C2 DOCK-type
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
24 sequences

DOC10_HUMAN (Q96BY6), DOC10_MOUSE (Q8BZN6), DOC11_DANRE (B0R034), 
DOC11_HUMAN (Q5JSL3), DOC11_MOUSE (A2AF47), DOCK1_HUMAN (Q14185), 
DOCK1_MOUSE (Q8BUR4), DOCK2_HUMAN (Q92608), DOCK2_MOUSE (Q8C3J5), 
DOCK3_HUMAN (Q8IZD9), DOCK3_MOUSE (Q8CIQ7), DOCK4_HUMAN (Q8N1I0), 
DOCK4_MOUSE (P59764), DOCK5_HUMAN (Q9H7D0), DOCK5_MOUSE (B2RY04), 
DOCK6_HUMAN (Q96HP0), DOCK6_MOUSE (Q8VDR9), DOCK7_HUMAN (Q96N67), 
DOCK7_MOUSE (Q8R1A4), DOCK8_HUMAN (Q8NF50), DOCK8_MOUSE (Q8C147), 
DOCK9_HUMAN (Q9BZ29), DOCK9_MOUSE (Q8BIK4), SPK1_ARATH  (Q8SAB7)
» more

PDB
[Detailed view]
7 PDB

3L4C; 6TGB; 6TGC; 7CLX; 7CLY; 7DPA; 8JHK