Entry: PS51676

General information about the entry

Entry name [info] FF
Accession [info] PS51676
Entry type [info] MATRIX
Date [info] JUN-2013 (CREATED); OCT-2013 (DATA UPDATE); OCT-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC51676
Associated ProRule [info] PRU01013

Name and characterization of the entry

Description [info] FF domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=56;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=56;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4295199; R2=0.0045070; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=1347; N_SCORE=8.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=904; N_SCORE=6.5; MODE=1; TEXT='RR';
/DEFAULT: M0=-43; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='Y'; M=-117,-132, -46,-105,-107,-128,-105,  32,  44, -58,-107,-110,-124,  54,  72,-112, -15,-110,-112,  73;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='R'; M= -18,-127, -20,  44,-121,-125,  44,  -3,  47,  -6,  10,-108,-119, -14,  48, -53,  15, -19,-131,-113;
/M: SY='E'; M= -20,-129,   6,  75,-128, -55,-109, -69,  53, -18,-116,-106,-115,   7,  43,-107,   4,-121,-130,-119;
/M: SY='A'; M=  57,  -4,  -3,   8, -46,-113,-114,   3,  36, -40,  14,  35,-120, -43, -19,   2, -30, -68,  13,-117;
/M: SY='K'; M= -26,-129,  -2,   5,-124,-123, -18,   3,  82, -77, -34,-105,-119, -97,  60, -27, -41, -33,  -4, -49;
/M: SY='E'; M= -14,-129,  33,  66,-131,-118,   1, -18,  24,-125,-118,  16, -22,  51,   6,  20, -62,-122,-133,-119;
/M: SY='E'; M=  37,-125,  36,  49,-121, -63, -10, -14,  10, -16,-113,  36,-119,  23, -55,  -5,-107, -47,-129,   6;
/M: SY='F'; M=-123,-125, -55,-128, 110,-134, -31,   0, -14,  -7,-100,-125,-134,-129, -23,-124,-116,   3,-100,  24;
/M: SY='K'; M=-115, -31,-107,  38, -11,-126,-109, -38,  77, -12,-111,-107,-119,  53,  46,-111, -56, -42,  -3,-113;
/I:         I=-25; MD=-63;
/M: SY='E'; M= -12,-128,  42,  51,-128,-120,-112, -67,  37, -35, -14, -23,-118,  24, -13,  21,  24,-121,  25,-119; D=-25;
/I:         I=-25; MD=-63;
/M: SY='M'; M= -23,  42,-134,-128,  21,-133,-120,   8,-124,  57,  75, -33,-133, -29, -30,-123, -22, -56,  25,  -9; D=-25;
/I:         I=-25; MI=0; MD=-63; IM=0; DM=-63;
/M: SY='L'; M=-119,-123,-136, -48,  19,-137,-121, -41,-128,  88,  22,-134,-134,-123,-126,-128,-116, -22,  53,-101;
/M: SY='E'; M= -64,-128,  36,  60, -21,-122,-109,-118,  55, -24,-115,   4,-117,  31,  10, -12,-109,   6,-130,-116;
/M: SY='E'; M=-110,-128,  48,  72,-127, -33,-108,-120, -44, -72,-118,  15,-116,  25,  16,  21,  -4,   9,-134, -28;
/M: SY='H'; M=  19,  49,-119,-114,-111,-121,  65, -16,  12,  26,  45, -18,-125,-108,  31,   1,   3, -50,-129,  -1;
/M: SY='Q'; M= -12,-127,  14,  26,-124,   1,  33, -64,  31, -49,-114,  18,  14,  39, -13,  20, -65,   8,-131, -15;
/M: SY='F'; M= -49,-126,-113,  37,  45,-126, -22,  25,  17, -49,-106, -24,   3,   8,  20,   7, -28,  30,-122, -40;
/I:         I=-14; MD=-36;
/M: SY='D'; M= -19, -20,  48, -35,-119,-122, -33,  34, -38, -26,  26,  13,   8, -48, -63,  40, -53,  -6,-135,  -2; D=-14;
/I:         I=-14; MI=0; MD=-36; IM=0; DM=-36;
/M: SY='T'; M=-122,-134,-127,-126,-132, -53,  40,  -3,  28, -74,-121, -42,-132,-124,-122, -18,  70,  16,-150,-127; D=-14;
/I:         I=-14; MI=0; MD=-36; IM=0; DM=-36;
/M: SY='S'; M=  26,-131,  -3, -53, -46,-120,-121,-121, -60, -27,-120,-117,  51, -39,-125,  54,  -7, -21,-131,  31; D=-14;
/I:         I=-14; DM=-36;
/M: SY='N'; M= -65,-127,  24,   0,  10,   8,  27,-124,  -4, -72,  10,  43, -48,   3, -12,  24,  34,-122,-129,  14; D=-14;
/I:         I=-14; DM=-36;
/M: SY='T'; M=  14, -29, -50,  -1,-119,-115,-118,   1, -19, -52,-112, -42,-117,   8,-114,  54,  73, -34,  69,-114;
/M: SY='T'; M= -40,-122, -21, -27,-122,-117,   5, -59,   8, -15,-112,  33,  31,   7,  21,  29,  69, -54,-133, -44;
/M: SY='W'; M=-125,-141,-143,-129,  37,-128,-132, -12, -11, -38,   7,-137,-131,-122,-122,-129,-129, -59, 164,  44;
/M: SY='E'; M= -63,-128,  27,  58,-129, -54,-109,-127,  14, -48,  -4,-103,  19,  32,  32,  49,  -4,-123,-132,-120;
/M: SY='E'; M= -37,-129,  46,  72,-130,-121,-107,-123,  29, -36,-117,   4,-115,  55, -18, -22,   3, -24,-133,-120;
/M: SY='I'; M=  39,-121,-126, -30,  43, -57,-124,  52,-121,  -1, -99,-120,-125, -35,-124, -37,  18,  38,-121, -14;
/M: SY='K'; M= -23, -31, -38,  21, -58,-121, -26,  -2,  43, -14,  31,-109,-120,  38,  25,  34, -46,  -4,-124,  19;
/M: SY='H'; M=   4, -14,  39, -10,-129,-117,  53, -66,  42,-124, -27,   5,  40,  35,  19,   5, -33, -33,-134,-116;
/M: SY='K'; M= -26,-126,-118,  10, -10,-128,   5,  34,  46,  -4,  45,-115,-123,-107,  26, -35,  -9,  22,  33, -10;
/M: SY='I'; M=-118,-125,   5,-126,  45,-136,  -7,  62,-127,  54,   1,-126,-131,-124,-127,-124,-113,  18,   1, -11;
/M: SY='S'; M= -38, -27, -54,  46,-122,  13,-112, -34,  22, -74,  47, -22,-118,  25, -30,  53,-105,  14,-130, -38;
/M: SY='N'; M= -26, -25,  39,  56,  10, -34, -44, -23,   5,-121,  -3,  60, -45,  -9, -27,   8,  -6, -63,-132,-115;
/M: SY='D'; M= -68,-129,  97,  38,-128,-118,  26,-128, -10, -19, -23,  13,-118,-102, -21,   1, -44,-126,-141, -28;
/M: SY='P'; M=-115,-133,  24,  30,-126,-122, -29, -21,  22,   2,-113, -22,  87,  17,   8, -15, -60, -65,-131,-121;
/M: SY='R'; M=  -6, -11, -16,  31, -36, -43,-109, -57,  30, -70,-115,-107, -47,  -1,  85,  -1, -54, -18,-129,-116;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='Y'; M= -63,  29,  -4,-122,  83, -56,-107,-112, -29,-106,-108,-120,-132,-118,  19, -52, -25,-115,  74,  93;
/M: SY='K'; M=   5,-127,  -2,  22,-119, -31,-110,  11,  38, -14,-110,   1, -45,  34,  36,  12, -13,-112,-125,  16;
/M: SY='A'; M=  52, -29,   3,  19,-119,-116,  -1, -62,  22, -20, -21, -10,  13,  17, -30, -20, -23,  -8,  36,   1;
/M: SY='M'; M=-115,-124, -27, -10,  26, -71,-120,  47,-123,  47,  61, -53,-128,-119,-124, -36, -56,  33,-121,   9;
/I:         I=-17; MD=-44;
/M: SY='D'; M=  -9,-130,  61,  18,-129, -27,  16, -49,-112, -13,-119, -25, -34,  15, -21,  37,  -5, -13,-141,-122; D=-17;
/I:         I=-17; MI=0; MD=-44; IM=0; DM=-44;
/M: SY='N'; M=-120,-132,  40,-109,-129,-121,-114,-125,  43,  15,-119,  67,  33,-111, -39,  18,-111,-126,-141,-126; D=-17;
/I:         I=-17; DM=-44;
/M: SY='E'; M=-114,-131,  31,  76,-125,   3,  -9,  18, -55, -26,  41,-110, -30,-102,  -6, -27,   0, -66,-135,-120; D=-17;
/I:         I=-17; MI=0; MD=-44; IM=0; DM=-44;
/M: SY='S'; M= -12,-133, -56,  33,-132,-125, -13,-127,  29, -20,-122, -47, -48,  15,  12,  49, -27, -27,  -5,-125; D=-17;
/I:         I=-17; DM=-44;
/M: SY='D'; M= -58,-135,  66,  58, -51,-127,   6, -63,  -5,-128, -40,-107, -23,  10, -29, -43,  21, -11,  -2,-122; D=-17;
/I:         I=-17; DM=-44;
/M: SY='R'; M=  29,   7,-118,-109,-130, -57, -13,-132,  17, -74,-119, -17,  11,   3,  86, -29,-116,-126,-131, -24; D=-17;
/I:         I=-17; DM=-44;
/M: SY='K'; M=-115,-129, -37,  64,-121,-125,-108, -59,  65,  24,  15,   4,-118,  27,  24,-111,-112,-117,-128,-116;
/M: SY='Q'; M=   8, -28,  41,  39,-125, -41, -20, -21,  30,  -9,-112, -17,-118,  58,   1, -21, -11, -27,-132,-117;
/M: SY='L'; M=  10,  37,-130, -65, -21, -72,-125,  29, -12,  55,   5,-124,-129,-121,-122,-116,  -5,  43,-128,-110;
/M: SY='F'; M=-124,-125,-135,-132, 109,-134,-115,  23,-127, -16,-100,-127,-134,-131,-126,-122,  -5,-101,   2,  65;
/M: SY='E'; M=-114,-129,  29,  66, -55, -29,-105,-123,   0, -16,-116,  59,-119,  39,  19, -46,-110, -33, -11,   6;
/M: SY='D'; M=  -5,-129,  72,  53, -15,-118, -30, -50,  20,-126,-120,   2,-117,  56,  -3,  -9, -50,-124,-133,-117;
/M: SY='H'; M= -67, -21, -23,-116,  35,-128, 102,-110, -11,   6,-102,-112,-129,-111, -51,-116, -61, -19,  29,  93;
/M: SY='I'; M=-114,   4,-132,-124,-103,-136,-126,  70,   2,  45,  13,-125,-128,  16,-121,-121, -57,  44,-128,-110;
/M: SY='E'; M= -31,-129,  16,  59, -14, -30,  35,-119,  31, -19,-113, -17, -47,  37,  26, -21, -52,  -2,-130,-114;
/M: SY='E'; M= -16,-127,  39,  40,  28, -26,   7, -27,  25, -71,-115,  22,-119,  40,   2,   2,  -9, -35,-128,-111;
/I:         E1=0; IE=-380; DE=-380;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_11 which contains 553'231 sequence entries.


Total number of hits 105 in 23 different sequences
Number of true positive hits 105 in 23 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.22 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 6
Feature key [info] DOMAIN
Feature description [info] FF
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
23 sequences

DRE4_SCHPO  (Q09685    ), PR35B_ARATH (F4JCC1    ), PR40A_ARATH (B6EUA9    ), 
PR40A_HUMAN (O75400    ), PR40A_MOUSE (Q9R1C7    ), PR40B_HUMAN (Q6NWY9    ), 
PR40B_MOUSE (Q80W14    ), PR40C_ARATH (Q9LT25    ), PRP40_SCHPO (O14176    ), 
PRP40_YEAST (P33203    ), RG190_DROME (Q9VX32    ), RHG05_HUMAN (Q13017    ), 
RHG05_MOUSE (P97393    ), RHG35_CANLF (P83509    ), RHG35_HUMAN (Q9NRY4    ), 
RHG35_MOUSE (Q91YM2    ), RHG35_RAT   (P81128    ), TCRG1_HUMAN (O14776    ), 
TCRG1_MOUSE (Q8CGF7    ), TCRGL_HUMAN (Q5VWI1    ), TCRGL_MOUSE (Q3B807    ), 
URN1_YEAST  (Q06525    ), YO61_CAEEL  (P34600    )
» more

UniProtKB/Swiss-Prot
False negative sequences
3 sequences

RGGA_ARATH  (O23523    ), RGGB_ARATH  (O23593    ), RGGC_ARATH  (Q9LVT8    )

		
PDB
[Detailed view]
17 PDB

1UZC; 2B7E; 2CQN; 2DOD; 2DOE; 2DOF; 2E71; 2JUC; 2K85; 2KFD; 2KIQ; 2KIS; 2KZG; 2L9V; 2LKS; 3HFH; 4FQG
» more

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission