PROSITE entry PS51776
View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry
| Entry name [info] | RH1 |
| Accession [info] | PS51776 |
| Entry type [info] | MATRIX |
| Date [info] |
01-OCT-2015 CREATED;
13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51776 |
| Associated ProRule [info] | PRU01112 |
Name and characterization of the entry
| Description [info] | RH1 domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=89; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=84; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6321311; R2=0.0054875; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=12700.2861328; R2=4.7751842; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1434; H_SCORE=19548; N_SCORE=10.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=705; H_SCORE=16067; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-33; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='S'; M= -46, -34, -31, 18, -24, -8, -91, -34, -30, -19, 10, -18, 6, -18, 17, 19, -25, -40,-106, -38; /M: SY='W'; M= 22,-100, 11, 16, -28, -5, -17, -42, -48, -40, 6, 1, -18, -34, -55, 5, -26, -26, 44, -42; /M: SY='M'; M= -1, -15, -45, 22, -28, 10, -1, -25, -42, -35, 30, -19, -6, -10, 4, -15, -26, -11, 0, -12; /M: SY='S'; M= -35, -98, 0, 14, -9, 14, -88, -36, -82, -44, -89, -15, -2, -35, 4, 40, 7, -11,-103, -38; /M: SY='C'; M= 10, 38, 0, -8, -21, -38, -91, -81, -54, 8, 23, -85, -2, -40, -93, 35, -11, -2,-105, -89; /M: SY='W'; M= -20, -97, 18, 5, 4, -4, -5, -28, -86, 19, 38, -85, -50, -84, -10, 13, -45, -5, 41, -80; /M: SY='D'; M= -62, 4, 54, 42, -96, -23, -24, -90, -47, -67, 45, 6, -39, -12, -10, 22, -9, -24,-107, -43; /M: SY='D'; M= 6, -94, 48, -22, -39, -54, -26, -94, 31, -96, -90, 7, -13, -74, 10, 31, 22, -43,-104, -34; /M: SY='P'; M= -9, 28, 27, -15, -50, -5, 3, -21, -47, -89, 15, -8, 45, -79, -19, 23, 15, -41, -99, 15; /M: SY='S'; M= 4, -22, 12, -2, 15, 14, -82, -20, -9, -65, 5, 22, 30, -77, -28, 31, -21, -27, -95, -23; /M: SY='S'; M= -4, 9, -53, 26, -17, -7, -30, -37, -35, 5, -28, -15, -23, -42, -28, 55, 10, -29, 7, -83; /M: SY='H'; M= 14, -23, 22, 29, -14, 2, 45, -29, -51, -61, -29, 24, -11, 35, -26, -3, 5, -51,-100, -82; /M: SY='L'; M= -53, -23, -23, 5, -41, -61, -86, 16, -86, 52, 38, -89, 12, -11, -41, -43, 4, 11, -94, -20; /M: SY='T'; M= -14, -87, -36, -34, -80, -50, -16, -25, -35, -3, 55, 10, -87, -77, -44, 38, 63, -3, -98, 1; /M: SY='V'; M= -3, -87, -10, -49, -85, -84, -88, -62, -82, -30, -75, 9, 14, -81, -33, 56, -17, 64,-105, -85; /M: SY='E'; M= -28, -94, 33, 66, -91, -34, -80, -51, -40, -44, 16, -11, 17, -15, -80, -22, -1, 31,-102, -43; /M: SY='D'; M= -86, -98, 89, -18, -31, -43, 15, -30, 4, -15, -30, 15, -90, -71, 42, -78, -79, -91,-107, -83; /M: SY='V'; M= -73, -86,-103, -97, -73,-104,-105, -6, -95, -31, -62, -98, -99, -97, -96, -87, -71, 102,-107, -81; /M: SY='Y'; M= -56,-100, -85, -35, -19, -92, 6, -16, -77, -78, -73, -83, -96, 53, -13, 8, -48, -82, 15, 113; /M: SY='D'; M= 1, -96, 69, 45, -53, -1, 24,-100, -31, -98, -91, 42, -85, 10, -4, -21, -48, -95,-106, -87; /M: SY='L'; M= -40, -91,-101, -46, -29,-103, -89, 60, -93, 63, 57, -96, -97, -51, -93, -91, -34, -27, -17, -30; /M: SY='A'; M= 93, -81, -86, -79, -30, -70, -88, -83, -82, -86, -81, -79, -86, -78, -86, 23, -28, -40, -95, -88; /M: SY='S'; M= 16, -90, -28, -29, -86, 32, 6, -86, 4, -34, -81, 8, -87, 29, -78, 45, 8, -21, -92, 23; /M: SY='D'; M= 11, 19, 38, 26, -86, -35, -9, 0, -48, 0, -76, 3, -88, -36, -38, 26, -23, 22,-103, -85; /M: SY='I'; M= -82, -92,-104,-100, 3,-107, -98, 83, -97, 26, 27, -97, -96, -94, -98, -92, -77, 43, -92, -73; /M: SY='Y'; M= -16, 5, -29, -90, -36, 75, -74, -92, -84, -89, -83, -3, -92, -82, -36, -37, -83, -91, -72, 89; /M: SY='K'; M= 21, 5, -25, -69, -39, -16, 19, -48, 50, -90, -82, -8, -85, 43, 31, 14, 28, -85, -96, -82; /M: SY='E'; M= -79, -99, 42, 102,-103, -26, -72,-102, -63, -96, -92, -71, -77, 19, -72, -74, -34, -96,-101, -91; /M: SY='F'; M= -88, 12,-105, -99, 93,-103, -88, -9, -97, 56, -19, -98,-103, -98, -95, -93, -83, -10, -74, -53; /M: SY='E'; M= -79, -98, -11, 97, -98, -92, -72, -95, 2, -27, -24, -74, -78, 46, -14, -36, -31, -91, -97, -88; /M: SY='R'; M= -9, -94, -41, -3, -92, -35, -78, -25, 62, -46, -80, -72, -29, -19, 63, 18, -13, -15, -95, -84; /M: SY='L'; M= -50, -89,-103, -96, -64,-103, -90, 57, -95, 67, 58, -98, -98, -89, -94, -92, -79, 14, -92, -73; /M: SY='I'; M= -6, -91, -96, -93, -73, -58, -96, 84, -88, -26, 2, -87, -91, -87, -16, 9, 7, 33, -96, -78; /M: SY='D'; M= 9, -94, 69, 28,-100, 16, 5,-100, -29, -97, -90, 33, -85, -8, 33, 5, -75, -94,-104, -87; /M: SY='R'; M= 15, -20, 9, 9, -90, -31, -21, -20, 16, -29, -12, -9, -87, 25, 52, -19, 13, 0, -98, -83; /I: I=-18; MD=-45; /M: SY='Y'; M= -60, 1, -90, -91, 68, -32, 67, -81, -87, -75, -74, -24, -33, -29, -85, -52, -86, -84, -63, 101; D=-18; /I: I=-18; MD=-45; /M: SY='G'; M= -72, -97, -12, -43,-101, 93, -88,-107, -84, -68, -93, -14, -89, -83, -3, -31, -17,-101, -97, -96; D=-18; /I: I=-18; MI=0; MD=-45; IM=0; DM=-45; /M: SY='P'; M= -20, 10, -42, 36, -94, -9, -12, -1, 18, -59, -27, 27, 50, 3, -10, 5, -15, -30,-100, -89; D=-18; /I: I=-18; DM=-45; /M: SY='D'; M= -7, -96, 71, 66, -40, 21, -76, -99, -47, -64, -91, -41, -2, -9, -79, -2, -77, -94,-101, -46; /M: SY='A'; M= 56, -2, -83, -20, -11, -46, -85, 1, -40, -45, -76, -8, 21, -19, -45, 33, -21, 18, -95, -35; /M: SY='V'; M= 11, -87,-100, -94, 28, -98, -97, 34, -93, 1, -61, -95, -36, -93, -94, -84, -73, 80, -93, -23; /M: SY='Q'; M= 8, -22, 21, 23, -92, -20, 26, -26, 5, -25, -79, 0, -85, 43, -10, 25, 23, -25,-100, -83; /M: SY='G'; M= -45, -93, 23, 30, -97, 60, -77, -99, -47, -97, -88, 21, -17, 0, 38, 7, 15, -93, -98, -89; /M: SY='L'; M= -50, -88, -34, -93, -25,-102, -89, 23, -94, 83, -50, -98, -99, -89, -93, -92, -79, 10, 27, -70; /M: SY='M'; M= -46, -87, -96, -87, -72, -37, -81, 18, -84, -10, 115, -87, -90, 32, -84, -83, -21, 52, -95, -73; /M: SY='P'; M= -49,-100, -35, -32, 28, -58, -32, -88, -34, -92, -84, -33, 111, -42, -87, 16, -7, -90, -91, -35; /M: SY='K'; M= -81, -93, -8, -71, -4, -92, 0, 14, 69, 34, -21, -41, 13, 12, 1, -40, -36, -46, -90, -75; /M: SY='V'; M= -74, -86, -99, -95, -30,-101, -97, 53, -92, 3, 25, -30, -95, -92, -94, -85, -18, 84, -98, -76; /M: SY='V'; M= -33, -88, -98, -38, -71, -39,-101, 66, -92, -27, -58, -93, -94, -92, -95, -84, -71, 85, -99, -78; /M: SY='R'; M= -33, -92, -27, -31, -44, -7, 2, -92, 7, -65, -82, 46, -88, -18, 79, 23, 8, -57, 9, -30; /M: SY='V'; M= 47, -17, -93, -88, -76, -88, -95, 30, -87, -21, -7, -87, -90, -87, -91, -73, 27, 72, -99, -81; /M: SY='L'; M= -84, -87,-101, -94, -19, -40, -85, -51, -95, 91, 8, -99, -28, -88, -92, -93, -81, -59, -88, -70; /M: SY='E'; M= -41, -97, -11, 111,-101, -91, -70,-101, -60, -94, -90, 3, -74, -21, -69, -73, -77, -94, -99, -91; /M: SY='M'; M= -77, 2, -77, 24, -76, -49, 30, -32, -22, 43, 54, 22, -88, 32, -77, 17, 15, -72, -94, -16; /M: SY='L'; M= -84, -87, -26, -92, -25,-102, -85, -50, -94, 90, 33, -98,-100, -87, -92, -93, -80, -16, -89, -70; /M: SY='E'; M= -47, -97, 70, 94, -99, -89, 4, -97, -64, -51, -89, -67, -78, -27, -73, -27, -76, -44,-103, -87; /M: SY='S'; M= 37, -87, -11, 29, -44, -22, -80, 1, -8, -27, -20, -17, -83, 24, -39, 45, 10, -13, -96, -83; /M: SY='F'; M= 23, 36, -92, -45, 49, -90, -83, -62, -87, 47, 25, -87, -94, -7, -87, 3, -10, 10, -84, 5; /M: SY='Y'; M= 46, 36, -86, -39, -38, -85, 45, -17, -42, -12, -69, -81, -90, -80, -32, -11, 15, 43, -89, 46; /M: SY='S'; M= 16, 18, -31, -5, -89, 3, -79, -50, 31, -34, -27, 32, -85, -10, -12, 45, -4, 14, -98, -85; /M: SY='R'; M= -44, -97, 26, 52, -91, -6, -21, -55, 20, -22, -81, -46, -10, 46, 56, -25, -78, -89, -93, -6; /I: I=-19; MD=-47; /M: SY='N'; M= -22, -18, -26, -77, -55, -53, -13, -13, 11, -25, -82, 75, -35, -13, 48, 10, -75, -35,-102, -32; D=-19; /I: I=-19; MI=0; MD=-47; IM=0; DM=-47; /M: SY='E'; M= -21, -98, 47, 52,-100, -21, 1, -47, -41, -55, -87, 12, 7, 45, 20, 4, -78, -57,-103, -88; D=-19; /I: I=-19; DM=-47; /M: SY='E'; M= -5, -25, 10, 50, -95, -3, 24, -34, 0, -93, -85, -25, -43, 22, 45, 22, -21, -89, -98, -34; D=-19; /I: I=-19; DM=-47; /M: SY='L'; M= -6, 7, -24, 41, -72, -57, -6, 8, -25, 52, -64, -35, -17, 9, -27, -8, -77, -69, -89, 22; /M: SY='Q'; M= -25, -28, 21, 21, -89, -25, 12, -30, 20, 1, -77, 38, -43, 47, 19, 9, 2, -50, -98, -82; /M: SY='C'; M= 4, 40, 1, 23, -83, -35, -82, -9, -25, 3, 0, 6, -39, 18, -31, -14, 34, 31,-100, -83; /M: SY='E'; M= -21, -93, 17, 87, -94, -87, 10, -91, 0, -21, -83, -26, -78, 3, -40, -4, 30, -86, -99, -85; /M: SY='L'; M= -5, -89, -89, -1, -5, -95, -84, 24, -78, 47, 15, -33, -93, -4, 28, -45, -76, 40, -91, -29; /M: SY='E'; M= -34, -31, 39, 72, -48, -32, -10, -41, -1, -63, 6, 15, -35, 26, -9, -14, 5, -48, -99, -84; /M: SY='E'; M= -38, -94, 5, 58, -87, -46, -74, -53, -33, 19, 13, -18, -29, 55, 44, -26, -12, -54, -95, -82; /M: SY='L'; M= -31, -25, -93, -12, -9, -97, -21, -18, -42, 81, -52, -92, -97, -23, -87, -4, -77, -19, -89, -72; /M: SY='R'; M= -32, -94, -16, -16, -89, -89, -74, -16, 55, -3, -75, -72, -87, 49, 70, -1, -22, -42, -93, -80; /M: SY='E'; M= 36, -90, 27, 37, 2, -36, 36, -49, 7, -8, 9, 9, -85, -1, 4, -45, -18, -26, -95, -78; /M: SY='E'; M= -6, -94, 60, 67, -25, -85, -73, -44, 6, -61, -85, 15, -81, 26, -7, -33, 3, -58, 2, -83; /M: SY='N'; M= -52, -90, -80, -27, -45, -26, 34, 32, 16, 18, -67, 41, -90, 1, 28, -19, -35, 30, -97, -77; /M: SY='E'; M= 3, -93, 19, 57, -36, -53, -7, -88, 18, -20, -21, 16, -83, 42, 17, -19, -1, -61, -6, -14; /M: SY='Q'; M= -38, -6, -10, -10, -91, -54, 52, -56, -21, -14, 10, -6, -37, 80, 56, 8, -20, -86, -96, -77; /M: SY='L'; M= -14, -88, -47, -90, -62, -51, -86, 4, -91, 84, -6, -95, -98, -14, -59, -50, -79, -31, 10, -72; /M: SY='E'; M= -22, -19, -73, 52, -15, -89, -25, -18, 11, 12, -28, -76, -29, 43, 21, 18, -3, -18, -91, -18; /M: SY='R'; M= 6, -23, -14, 26, -15, -37, -31, -32, -9, 0, -3, 7, -86, -3, 34, 34, 19, -45, 1, -10; /M: SY='Q'; M= -55, -99, 38, 68, -99, -88, 6, -95, 6, -63, -38, -38, -15, 80, 4, -24, -78, -62, -3, -83; /M: SY='Y'; M= -82, 2, -82, -54, 3, -39, -18, -57, 52, 11, -11, -2, -2, -8, 21, -18, -6, -42, -78, 68; /M: SY='E'; M= -51, -14, 0, 69, -92, -22, -29, -32, 7, -29, 7, -17, 19, 25, -14, 0, 6, -29, -97, -44; /M: SY='R'; M= -10, -95, -20, 46, -38, -44, -25, 5, 41, -34, -78, -28, -85, 24, 59, -74, 2, -81, -92, -21; /M: SY='E'; M= -19, -95, -13, 67, -92, -54, 0, -89, 44, -7, -27, -73, -2, 6, 36, -12, -43, -48, -96, -84; /M: SY='K'; M= 26, -92, -42, -11, -90, -5, -6, -27, 57, -29, -79, -20, -15, -66, 55, -17, -11, -46, -94, -40; /M: SY='Q'; M= 37, -91, 9, 43, -96, -35, -28, -90, 25, -63, -82, 7, -16, 48, 12, -17, 4, -40, -97, -86; /M: SY='E'; M= 2, -93, 19, 51, -14, -7, 3, -32, -9, 22, -74, -34, -24, 41, -14, -3, -77, -55, -93, -37; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 25 in 25 different sequences |
| Number of true positive hits | 25 in 25 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | RH1 |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
25 sequences
JIP3_DROME (Q9GQF1), JIP3_DROPS (Q29EP6), JIP3_HUMAN (Q9UPT6), JIP3_MOUSE (Q9ESN9), JIP3_RAT(E9PSK7), JIP4_HUMAN (O60271), JIP4_MOUSE (Q58A65), JIP_CAEEL (P34609), RILP_HUMAN (Q96NA2), RILP_MOUSE (Q5ND29), RIPL1_BOVIN (Q17QG3), RIPL1_DANRE (A0PJT0), RIPL1_HUMAN (Q5EBL4), RIPL1_MOUSE (Q9JJC6), RIPL1_RAT (D3ZUQ0), RIPL1_XENLA (Q0IHE5), RIPL1_XENTR (A0PJP4), RIPL2_BOVIN (A4IFK7), RIPL2_DANRE (A4IGC3), RIPL2_HUMAN (Q969X0), RIPL2_MOUSE (Q99LE1), RIPL2_RAT (Q6AYA0), RIPL2_XENLA (Q6IP02), RIPL2_XENTR (Q0P4J3), RIPL_DROME (O76878)» more
|
| PDB [Detailed view] |
5 PDB
4KP3; 8PR2; 8PR3; 8PR4; 8PTK |