PROSITE entry PS51781
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General information about the entry
| Entry name [info] | SH3B |
| Accession [info] | PS51781 |
| Entry type [info] | MATRIX |
| Date [info] |
01-NOV-2015 CREATED;
22-NOV-2017 DATA UPDATE; 27-MAR-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51781 |
| Associated ProRule [info] | PRU01117 |
Name and characterization of the entry
| Description [info] | SH3b domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=66; /DISJOINT: DEFINITION=PROTECT; N1=1; N2=66; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1614432; R2=0.0073224; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1139; N_SCORE=10.5; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=593; N_SCORE=6.5; MODE=1; TEXT='R?'; /DEFAULT: M0=-27; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='E'; M= 25, -74, -55, 45, -18, -6, -60, -31, 21, -71, -65, -56, -10, 29, -55, 32, 6, -65, -72, 20; /M: SY='T'; M= 5, -72, 40, 34, -76, 4, -59, -70, 28, -71, 4, 13, -9, 3, -54, -17, 49, -34, -83, -69; /M: SY='T'; M= -20, -67, -54, 18, -67, -29, -60, -19, -4, -65, 2, 28, -64, -53, -60, 50, 67, -4, -80, -6; /M: SY='A'; M= 51, -70, -61, -22, -61, -1, -57, -66, 37, -29, -60, -21, -68, 22, -7, 21, -55, -36, -65, 51; /M: SY='T'; M= -57, -70, -61, -20, -6, -69, 13, 23, -13, -32, 4, 23, -69, -16, -2, 23, 57, 6, -71, 37; /M: SY='V'; M= -55, -70, -77, -73, 19, -77, -75, 53, -19, -43, -45, -69, -75, -69, -71, 30, -51, 71, -74, 4; /M: SY='T'; M= -27, -67, -60, -61, -66, 4, -63, 2, 16, -62, -1, 9, -66, -56, -16, 50, 60, 11, -79, -14; /I: I=-26; MD=-65; /M: SY='A'; M= 34, -73, 4, -21, -66, 34, -68, 5, -67, -33, -60, -12, 13, -65, -72, -3, -21, 23, -76, 19; D=-26; /I: I=-26; MI=0; MD=-65; IM=0; DM=-65; /M: SY='D'; M= -7, -71, 54, 26, -73, 4, -59, -68, -54, -12, 4, 11, -24, -5, -13, 11, 52, -64, -84, -67; /M: SY='W'; M= -9, -75, 20, -1, 34, 25, -62, -68, -22, -68, 4, 33, 42, -59, -65, 22, -57, -33, 67, -8; /M: SY='L'; M= 38, -68, -73, -17, -53, -72, -70, 28, -27, 54, 4, -70, -73, -64, -69, -59, 20, 1, -75, -60; /M: SY='N'; M= -63, -73, 16, 16, -14, -61, -50, 6, -51, -70, -64, 94, -13, -52, 3, -21, -15, -67, 41, 20; /M: SY='V'; M= -58, -69, -81, -77, -3, -3, -75, 31, -74, 40, 43, -74, -77, -72, -75, -67, -4, 62, -76, -56; /M: SY='R'; M= -67, -82, -64, -53, -66, -77, -52, -75, 15, -31, 9, -58, -75, -42, 107, -62, -65, -71, -70, 24; /I: I=-30; MI=0; MD=-77; IM=0; DM=-77; /M: SY='S'; M= 6, -68, 25, 31, -75, -60, -2, -69, -19, -72, -66, -48, -63, 2, -15, 65, 48, -27, -84, -66; /M: SY='G'; M= -10, -76, -18, 34, -78, 72, -65, -22, 35, -75, -68, -52, -65, -54, -18, -26, -23, -29, -76, -72; /M: SY='P'; M= 34, -81, -15, -54, -83, -10, -67, -73, -16, -79, -68, -12, 106, 0, -68, -55, -57, -72, -79, -78; /M: SY='G'; M= -54, -72, 31, 11, 15, 58, -61, -75, -16, -32, -68, 31, -67, -57, -64, 35, 7, -71, -77, -64; /M: SY='T'; M= 32, -69, -8, -19, -62, -66, 25, 0, -58, 15, -53, 27, -70, -58, 14, -13, 40, 3, 40, -60; /M: SY='S'; M= 6, -71, 41, 7, -73, -58, 38, -73, -54, -37, -65, 26, -4, 36, -58, 61, -13, -69, -82, -10; /I: I=-30; MI=0; MD=-77; IM=0; DM=-77; /M: SY='Y'; M= 21, 9, -64, -28, -9, -3, -23, -2, -15, -60, 19, -3, -71, -58, -63, 43, 0, -58, 37, 72; /M: SY='P'; M= -34, -78, 27, 12, -81, 5, -60, -77, 37, -79, -70, 7, 75, -9, -7, 7, 11, -74, -81, -72; /M: SY='I'; M= -58, -73, -67, 0, -60, -9, -70, 58, 12, -5, -47, -8, -71, 25, -21, -26, -10, 45, -78, -62; /M: SY='I'; M= -10, -71, -77, -73, -55, -31, -75, 62, -67, 12, 7, -69, -74, -67, 3, 8, -20, 53, -78, -60; /M: SY='G'; M= 11, -71, 4, -26, -60, 55, -3, -19, -63, -35, -61, -54, -68, -62, -69, -16, 52, -20, -69, 48; /I: I=-30; MD=-77; /M: SY='T'; M= -58, -74, -62, -1, -76, -71, -65, -7, 22, -69, -64, -55, -69, 46, 3, 41, 55, 0, -85, -69; D=-30; /I: I=-30; MI=-77; IM=-77; DM=-77; /M: SY='I'; M= 0, -70, -83, -78, 33, -36, -77, 57, -76, 35, -39, -76, -78, -74, -77, -68, -58, 52, -71, -52; /M: SY='N'; M= -31, -75, 14, 7, -70, -66, 2, -66, 40, 1, -60, 41, 34, 19, 15, 13, -55, -24, -78, -9; /M: SY='K'; M= 15, -73, 5, -17, 4, 25, -61, -67, 54, -17, -61, -54, -11, 8, -21, 14, -19, -27, -71, -4; /M: SY='G'; M= -51, -78, -65, -26, -78, 98, -71, -89, -67, -84, -75, -53, -69, -65, -29, -51, -69, -84, 67, -71; /M: SY='D'; M= -57, -74, 60, 45, -76, -3, -57, -19, -52, -44, 4, -10, -64, 39, -59, 33, 31, -66, -84, -67; /M: SY='K'; M= -8, -74, -58, 17, -9, -5, 4, 20, 47, -64, -59, -16, -10, -16, 19, 6, 22, -30, -73, -5; /M: SY='F'; M= -37, 9, -81, -77, 57, -81, -73, 45, -74, 10, -43, -74, -78, -75, -75, -18, -11, 56, -65, 16; /M: SY='T'; M= -59, -73, 6, -11, -71, -66, 24, -70, 44, -71, -2, 29, 41, -3, -15, -2, 61, -66, -79, 0; /M: SY='I'; M= -61, -73, -72, -70, -49, -79, -67, 61, 19, 4, -43, 17, -75, -65, -29, -64, -9, 49, -70, 40; /M: SY='I'; M= -60, -73, 25, 6, -12, -2, -66, 37, -28, 37, -46, -63, -73, -63, -68, -2, 2, 14, -71, 21; /M: SY='W'; M= -22, 36, 56, 22, -16, 39, -63, -75, -24, -74, -70, -17, -68, 3, -19, 11, -25, -23, 72, -63; /M: SY='F'; M= -44, -72, -16, 24, 37, -70, -61, -19, 31, -59, -58, -57, -69, -10, 1, 36, 14, 28, -68, 21; /M: SY='D'; M= -28, -73, 60, 10, -72, -6, -58, -27, 30, -33, 38, 24, -67, -3, -55, 18, -21, 7, -84, -66; /M: SY='N'; M= 1, -70, -57, -20, 16, 37, -60, -66, 28, -35, -62, 41, -68, -57, -58, 19, 31, -20, -70, 19; /I: I=-14; MD=-37; /M: SY='N'; M= -78, -94, 2, -24,-101, 17, -75, -99, -19,-100, -90, 56, -88, 23, -77, -26, 4, -96,-105, -91; D=-14; /I: I=-14; MI=0; MD=-37; IM=0; DM=-37; /M: SY='H'; M= 11, -94, -81, -83, -94, -35, 51, -35, -5, -48, -82, 27, -93, -80, -82, -74, 8, -38,-109, -85; D=-14; /I: I=-14; DM=-37; /M: SY='D'; M= -58, -76, 53, 0, -71, 41, -61, -2, 24, -69, -64, 19, -6, -5, -59, -23, -11, 11, -78, 2; /M: SY='W'; M= -74, -96, -94, -76, -39, -75, -85, -24, -70, -33, -66, -89, -79, -1, -72, -78, -82, -77, 169, 44; /M: SY='Y'; M= 34, -71, -20, -68, -9, -69, -4, 36, -66, -26, -50, 18, -74, -65, -69, -57, 8, 32, 37, 62; /M: SY='Q'; M= -24, -77, -56, 35, 16, 0, -3, -66, 54, 6, -57, -56, -68, 59, -13, -58, -61, -67, -66, 22; /M: SY='V'; M= -58, -71, -82, -79, -49, -85, -79, 70, -75, -38, -40, -76, -76, -75, -77, -67, -12, 76, -74, 28; /M: SY='Q'; M= -58, -75, 16, 29, -72, -68, 7, -22, 34, -68, 4, 5, -65, 58, 8, 14, 34, -33, -78, -8; /M: SY='Y'; M= -65, -75, 23, -64, 9, -35, 5, -56, -62, 20, -52, 11, -76, -61, -15, -12, 24, -32, 59, 85; /M: SY='N'; M= -4, -73, 2, 2, -75, 33, 17, -77, 37, -77, -68, 38, 14, -51, -24, 33, 6, -72, -78, -10; /I: I=-19; MD=-47; /M: SY='N'; M= -39, -84, 24, -24, -78, -32, -67, -84, 15, -39, -78, 45, -80, -63, -67, 38, -14, -82, 22, 16; D=-19; /I: I=-19; MI=0; MD=-47; IM=0; DM=-47; /M: SY='G'; M= -23, -80, -65, -30, -87, 84, -72, -91, -31, -88, -78, 11, -73, -67, -21, -28, -3, -84, -82, -81; D=-19; /I: I=-19; DM=-47; /M: SY='E'; M= -13, -73, -52, 52, -71, -68, -58, -28, 46, -42, -61, -54, -64, 29, 13, 23, 24, -6, -75, -5; /M: SY='T'; M= -57, -71, -58, 2, -68, -6, -62, 11, 45, -65, -60, -11, -65, -52, 36, -16, 70, -27, -77, -10; /M: SY='G'; M= 17, -75, -15, -19, -72, 85, -66, -34, -66, -76, -68, -53, -68, -13, -71, -26, -63, -39, -70, 23; /M: SY='W'; M= -71, -85, -81, -77, 19, -77, -56, -17, -69, -55, -55, -80, -82, -67, -69, -72, -71, -7, 132, 106; /M: SY='V'; M= -58, 35, -83, -78, -52, -85, -80, 62, -73, 11, 16, -76, -78, -74, -21, -69, -55, 72, -81, -59; /M: SY='P'; M= 26, -71, -19, -54, -18, -60, 14, -68, 3, -36, -63, 40, 47, 19, 8, 40, -8, -32, -79, -64; /I: I=-30; MD=-77; /M: SY='T'; M= -8, -84, -76, -76, -86, 11, -79, -31, -73, -34, -77, -12, -20, -9, -22, 32, 44, -75, -96, -83; D=-30; /I: I=-30; MI=-77; IM=-77; DM=-77; /M: SY='K'; M= -56, -75, -16, -27, -76, 44, 54, -27, 55, -74, -64, 24, -67, 24, -48, 24, -56, -18, -79, -64; /M: SY='W'; M= -70, -82, 46, -59, 52, -30, -55, -66, -59, -61, -61, -17, -77, 20, 12, -65, -67, -70, 105, 81; /M: SY='L'; M= -61, -70, -76, -71, -14, -29, 48, 23, -18, 53, -39, -69, -77, -68, -69, -66, 12, 47, -77, -54; /M: SY='W'; M= -54, -71, -60, 11, -61, -30, 39, -7, -23, -18, 4, -55, -67, 1, -62, 50, 48, 3, 68, 4; /M: SY='N'; M= -60, -72, 32, -53, -15, -63, -56, -27, 20, -34, 37, 66, 28, -10, -20, 5, 32, -20, -83, -64; /M: SY='T'; M= 16, -70, 22, 1, 39, -14, -65, -1, 19, 7, -55, -56, -68, -59, -11, -26, 47, -54, -72, -55; /M: SY='S'; M= -2, -78, 20, -24, -73, -39, -65, -21, 29, -74, -68, 14, 17, -11, -60, 30, 5, -5, -81, 19; /I: E1=0; IE=-255; DE=-255;» more |
Post-processing [info]
| COMPETES_HIT_WITH | PS50002 |
Numerical results [info]
| Total number of hits | 57 in 45 different sequences |
| Number of true positive hits | 57 in 45 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 2 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 96.61 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 4 |
| Feature key [info] | DOMAIN |
| Feature description [info] | SH3b |
| Version [info] | 2 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
45 sequences
ALE1_STACP (O05156), BCN5_CLOPF (P08696), BLYA_BACSU (O31982), CWL_CLODR (P0DX27), DPP6_LYSSH (P39043), ENLYS_BPSH5 (B8QIR1), LSTP_STASI (P10547), LSTP_STAST (P10548), LYS_CLOPE (P26836), LYTA_STAAU (P24556), LYTD_BACSU (P39848), LYTH_STAA3 (Q2FG95), LYTH_STAA8 (Q2FXU3), LYTH_STAAB (Q2YT98), LYTH_STAAC (Q5HFD1), LYTH_STAAM (Q7A2R2), LYTH_STAAN (Q7A588), LYTH_STAAS (Q6G8T7), LYTH_STAAU (O32421), LYTH_STAAW (Q7A0Q6), LYTH_STAEQ (Q5HNS0), LYTH_STAES (Q8CP02), LYTH_STAHJ (Q4L6X7), LYTH_STAS1 (Q49Y70), LYTO_STAA8 (Q2FX77), P60_LISGR (Q01835), P60_LISIN (Q01836), P60_LISIV (Q01837), P60_LISMO (P21171), P60_LISSE (Q01838), P60_LISWE (Q01839), SPKD_SYNY3 (P54735), TAGH_BACAN (Q81K31), TAGH_BACCZ (Q630Y3), Y1605_HAEIN (P44272), Y260_TREPA (O83284), YFHK_BACSU (O31579), YGIM_ECO57 (P0ADU0), YGIM_ECOL6 (P0ADT9), YGIM_ECOLI (P0ADT8), YGIM_SHIFL (P0ADU1), YRAI_BACSU (O07909), YRAJ_BACSU (O07934), YRVJ_BACSU (O32041), YWSB_BACSU (P96729)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
2 sequences
LYS_BPB30 (Q8HA43), PH_STAA8(Q2FYD8) |
| PDB [Detailed view] |
6 PDB
1R77; 4LXC; 5LEO; 5NMY; 6RJE; 6RK4 |