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PROSITE entry PS51799


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General information about the entry

Entry name [info] ZF_C2H2_AKAP95
Accession [info] PS51799
Entry type [info] MATRIX
Date [info] 01-MAY-2016 CREATED;
01-MAY-2016 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51799
Associated ProRule [info] PRU01140

Name and characterization of the entry

Description [info] Zinc finger C2H2 AKAP95-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=24;
/DISJOINT: DEFINITION=PROTECT; N1=3; N2=22;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.5329590; R2=0.0056179; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1152; N_SCORE=10.0; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=529; N_SCORE=6.5; MODE=1; TEXT='R?';
/DEFAULT: M0=-78; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='C';  M=-139, 161,-159,-159,-149,-154,-159,-156,-154,-146,-147,-145,-169,-162,-161,-141,-139,-143,-179,-160;
/M: SY='S';  M=  46,  23,  17,-136,   8, -85,-140,-105,-139, -41,  28, -78,-145, -77,-143,  85, -78, -28,-156,-139;
/M: SY='A';  M=  73,-143,-154,-147,  48,-143,-149, -12,-148,  34,-124,-149, -42,-146,-149,-133,-134,  30,-146,-131;
/M: SY='C';  M=-139, 161,-159,-159,-149,-154,-159,-156,-154,-146,-147,-145,-169,-162,-161,-141,-139,-143,-179,-160;
/M: SY='D';  M=-140,-156,  87,   1,-159, -92, -28,-159,  80,-157,-150, -47,-142, -33,   6,  -1,-134,-155,-161,-145;
/M: SY='F';  M= -59,-148,-157,-153,  69,-157,-141, -26,-150,  28,  44,-151,-157,-149,-149, -17, -23,  50,-133,  66;
/M: SY='R';  M=-145,-155,-143,  10,  58,-156,  44,-137,-124,  28,-128,-140,-154,  42,  74,-142,-142,-140,-138,  44;
/I:         I=-30; MD=-77;
/M: SY='I';  M=-170,-180,-192,-188, -63,-195,-188,  64,-185,   8,-142,-185,-184,-182,-186,-180,-165,  16,-182,-163; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='P';  M=-133,-151,-140,-136,-150,-142,-144, -63,-138, -10,-139,-135,  98,-139,-147,  51,  72,-139,-159,-148;
/M: SY='F';  M=  29, -33,  34, -15,  76,-145,-139,-131,-142, -18,  70,  12, -50,-141,-145,   0,   1, -43,-143, -77;
/M: SY='Q';  M= -71,-152,  16,  40, -78,-145,   6,-136, -72, -16, -28,  48,-147,  67, -89,  18,-132,  24,-148,  53;
/M: SY='H';  M= -18,-154,  18,  38,  42, -38,  51,  -5, -38, -46,-137,  13,   7,  26,  32,  -2,-136, -69,-149, -10;
/M: SY='W';  M= -24,-154,  15,  58,-153,   7,  39, -66,  18,-151, -46, -90,-142,  40, -10,  42, -31, -77,  62,-139;
/M: SY='E';  M= -69,-151,  27,  75, -62, -61, -16, -10,-131,   2, -68,-132,-142,  19,-137,  43,   3,   2,-158,-142;
/M: SY='I';  M=-140,-150,-162,-157,-125,-164,-153,  82,-154,  44,  73,-155,-154,-149,-154,-150,-136,  38,-153,-133;
/M: SY='Q';  M=  -6,-155, -32,  51,-155, -51, -41, -56,   9, -22, -17,  -7,-143, 102,  -9, -21, -36,-146,-154,-142;
/M: SY='Q';  M=  27,-152,  16,  25,-155,-142,-133,-150,  51, -43,-140,   1,-143,  70,  36, -11, -19, -79,-155,-143;
/M: SY='H';  M=-147,-159,-131,-131,-145,-149, 158,-164,-136,-146,-131,-120,-147,-125,-130,-136,-145,-163,-181,-114;
/M: SY='L';  M=-142,-146,-158,-153,  42,-161,-147,   0,-152,  79,  21,-153,-157,-149,-151,-146,  31,  -8,-146,-126;
/M: SY='R';  M= -14,-154,  33,  44,-154, -43,  14,-149,  47,-149,-142,-128,-143,  35,  51, -19,  14, -10,-157, -72;
/M: SY='S';  M=-120,-141,-133,-135,-151, -52,-137,-149,-134,-153,-147, -38,-141,-128,-139, 112,  35,-142,-161,-144;
/M: SY='Q';  M=  -2,-152, -64,   2,-151,-145, -18, -80,  45, -36,  -8, -49,  48,  51,  30,  11,  20,  -7,-155,-143;
/M: SY='F';  M= -58,-150,  65,  37,  65, -60,-137,-138,-137,  -7,  34,-131,-146, -31,-142,  13,  36, -98,-147, -20;
/M: SY='H';  M=-147,-159,-131,-131,-145,-149, 158,-164,-136,-146,-131,-120,-147,-125,-130,-136,-145,-163,-181,-114;
/I:         E1=0; IE=-255; DE=-255;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 28 in 14 different sequences
Number of true positive hits 28 in 14 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Feature key [info] ZN_FING
Feature description [info] C2H2 AKAP95-type
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
14 sequences

AKAP8_CANLF (Q5VK71), AKAP8_HUMAN (O43823), AKAP8_MOUSE (Q9DBR0), 
AKAP8_RAT   (Q63014), AKP8L_HUMAN (Q9ULX6), AKP8L_MOUSE (Q9R0L7), 
ZN326_BOVIN (F1MJM0), ZN326_CHICK (Q5ZJ02), ZN326_DANRE (A2CEZ5), 
ZN326_HUMAN (Q5BKZ1), ZN326_MOUSE (O88291), ZN326_PONAB (Q5RCA4), 
ZN326_XENLA (A2RV70), ZN326_XENTR (Q28F29)
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