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PROSITE entry PS51810


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General information about the entry

Entry name [info] ZF_CCHC_FOG
Accession [info] PS51810
Entry type [info] MATRIX
Date [info] 01-SEP-2016 CREATED;
01-SEP-2016 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51810
Associated ProRule [info] PRU01153

Name and characterization of the entry

Description [info] Zinc finger CCHC FOG-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=34;
/DISJOINT: DEFINITION=PROTECT; N1=4; N2=31;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6549518; R2=0.0111699; TEXT='-LogE';
/CUT_OFF: LEVEL=0; SCORE=1553; N_SCORE=20.0; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=345; N_SCORE=6.5; MODE=1; TEXT='R?';
/DEFAULT: M0=-68; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='P';  M=   2,-154,  -3, -18,  -2, -32, -61,  -1,  13,  -4, -24, -26,  42,   4, -47,  16,   4,   4,-156, -48;
/M: SY='P';  M=  -7,-155, -21, -14, -72, -11, -44, -39, -50, -30, -34,  -8,  60,   8,  13,  15,   6,  27,-161, -92;
/M: SY='P';  M=  15,-155,  18, -24, -61, -38, -35, -71,  30,  12, -52,  15,  42,   7, -11,   0, -18, -50,-158, -51;
/M: SY='P';  M=  13,-101, -37, -32,-148, -14,   4, -58,  -7, -10,   0, -40,  62,  43, -72,   7,   5, -11,-156,   0;
/M: SY='D';  M= -26, -96,  57, -68, -41,  24, -46, -54,   8, -34, -13,  29,  11,   6, -91,  16,  -8, -19,-160, -26;
/M: SY='Y';  M= -25, -81,  26, -36,-142,  12,  17, -11,  10, -59, -68, -27,   9,  44,   4, -31, -58,  12,-150,  50;
/M: SY='H';  M= -11, -88,-143,-139,  40,-150,  79, -83,  33, -14, -28, -21,-151,-134,  32,  10,  20, -87,-147,  33;
/M: SY='Y';  M= -47,-156, -77,  26,   8, -62,   5,  12,  15, -39,  11,-142,  14, -84, -27, -53,  20, -53,-136,  85;
/M: SY='C';  M=-141, 157,-161,-161,-152,-157,-161,-158, -76,-149,-149,-147,-171,-164,-162,-144, -78,-146,-181,-162;
/M: SY='K';  M=  12, -20, -25,  28,  12, -76, -58, -89,  40, -40,  -3, -56,   7,  21,  18,  -9,  19, -17,-155, -85;
/M: SY='E';  M=  42,-151,  27,  48, -74, -72,  -7,-143,-109, -24, -25, -29,  26, -40,-143,  21,   8,  -5,-161, -60;
/M: SY='C';  M=-141, 158,-161,-161,-151,-157,-161,-157,-157, -89,-148,-147,-172,-164,-163,-144,-141,-145,-181,-161;
/M: SY='D';  M=-139, -89,  69, -24, -67,  53, -18,-163,  28,-162,-153,  66,-148, -91, -11, -40,-137,-160,-164,-150;
/M: SY='I';  M=-145,-158,-167,-165,-130,-171,-167, 111,-160, -92,-117,-158,-156,-157,-163,-154,-139,   5,-156,-138;
/M: SY='W';  M= -56, -44,-142, -57,-151, -67, -27,-102,  26,-150,-144, -58, -96,  34,  50,  52,  35,   7,  60, -83;
/M: SY='F';  M=-157,-155,-168,-164, 122,-164,-145,-132,-159,-124,-133,-158,-168,-167,-156,-155,-149,-137,-121,  46;
/M: SY='N';  M= -56,  30,-133, -49,-111, -95,  -3,-130, -62,-121, -21,  77,-151, -51,  15,  65,  21,-150,-163,   5;
/M: SY='S';  M=-135,-152,-136, -87, -46,-121, -77,-155,  40,-121, -83,  48,-150, -84,  14,  80, -54,-151,-153,  41;
/M: SY='H';  M= -12,-154,-151,   5, -36,-158,  52,  12, -79,  41,  31, -57,   3, -36,-108, -66, -42,  23,-154,  20;
/M: SY='E';  M= -62,-156,  37,  62,-160,-145, -87,-157,  24,-158,-152,  41,-146, -86,   8,  46, -59, -33,-166,-151;
/M: SY='N';  M= -46,-147, -49,-141,-154, -95,-136,-147,-135, -65,-146,  99,-149,-137,-143,   2,  77, -51,-173,-151;
/M: SY='Y';  M=-153,-157,-161,-159,  67,-164,-135,-127,-155,  52,-123,-159,-167,-152,-152,-154,-147,-133,-124, 100;
/M: SY='Q';  M= -89,-157, -67,  -4, -87,-140, -94,  29, -17,  39, -12, -21,-155,  50,  25, -48,  -6, -14,-152,  20;
/M: SY='A';  M=  88, -66,-152,-145,-152, -61,-154, -37, -86,-141,-138,-146,-150,-145,-151,-127,   1,  37,-161,-151;
/M: SY='H';  M=-151,-163,-135,-136,-150,-153, 153,-168,-140,-151,-136, -31,-152,-129,-134,-141,-149,-168,-185,-119;
/M: SY='K';  M= -86,-160,-140,-126,-157, -79,-140, -83,  97, -14,-142,-134,-148,  59, -11,-139,-141, -54, -63,-146;
/M: SY='Q';  M= -11,-155, -97, -42,-120,-150,-138,-146,  59, -35,  60, -27,-148,  67,  28, -55,  37,-144,-157,-144;
/M: SY='Y';  M= -80,-159,-111,-151,  69,-157,  80,-139,-147, -26,-132,  -8,-162, -99, -77, -67,-146,-101,-125, 104;
/M: SY='Y';  M= -97,-109,-152,-154, -13,-158, -56,-139,-147,-135,-132,-152, -59, -91,-144, -38,-146,-143,-111, 136;
/M: SY='C';  M=-142, 156,-162,-162,-153,-158,-162,-160,-158,-151,-151,-148,-173,-166,-165, -70, -95,-147,-183,-163;
/M: SY='S';  M=  29, -72,-141,-105,-120, -68,-143, -90, -25, -76,-147, -18,  59,  12, -37,  76,  -9,-110,-161,-151;
/M: SY='S';  M=  32,-150,-140,-100,-156,  21,  40,-106,  33,-155,-147, -11,-110, -46, -93,  65,   8, -54,-162,-147;
/M: SY='R';  M= -34,-160,-142, -64,-156, -25,  46,-109,   0, -97,-111, -55, -64, -43,  99, -25,  14,-154,-160, -95;
/M: SY='H';  M=  10, -84, -78, -13, -63, -44,  73, -56, -20, -53, -35,  11,  41,  55,  16, -11,   1, -79, -15, -98;
/I:         E1=0; IE=-255; DE=-255;
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Post-processing [info]

COMPETES_HIT_WITH PS50157; PS51811

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 32 in 7 different sequences
Number of true positive hits 32 in 7 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 5
Feature key [info] ZN_FING
Feature description [info] CCHC FOG-type
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
7 sequences

FOG1_DANRE  (P60622), FOG1_HUMAN  (Q8IX07), FOG1_MOUSE  (O35615), 
FOG1_XENLA  (Q9I9K0), FOG2_HUMAN  (Q8WW38), FOG2_MOUSE  (Q8CCH7), 
USH_DROME   (Q9VPQ6)
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PDB
[Detailed view]
5 PDB

1FU9; 1FV5; 1JN7; 1Y0J; 2L6Z