PROSITE entry PS51844
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General information about the entry
| Entry name [info] | SH3_LIKE |
| Accession [info] | PS51844 |
| Entry type [info] | MATRIX |
| Date [info] |
22-NOV-2017 CREATED;
26-FEB-2020 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51844 |
| Associated ProRule [info] | PRU01190 |
Name and characterization of the entry
| Description [info] | Myosin N-terminal SH3-like domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=50; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=45; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6695542; R2=0.0069741; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6366.6386719; R2=1.6386719; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1123; H_SCORE=8207; N_SCORE=10.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=550; H_SCORE=7268; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-40; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='D'; M= -39, -16, 73, 35,-103, -72, -30, -27, -4, -51, 5, -43, -95, -29, 1, 27, 42, -74,-114, -26; /M: SY='V'; M= 29,-101, 30, 33,-100, -9, -94, -18, 27, -38, -89, -86, -97, -8, -20, 15, -84, 42,-111, -97; /M: SY='K'; M= -88, -24, -46, -84, -34, 60, -91, -55, 83,-105, -96, -31, -97, -81, 4, -54, -34, -56,-100, 9; /M: SY='T'; M= -21, -99, -11, -42, -98, -96, -91, -90, 55, 2, -16, -21, -96, -20, 3, 38, 62, -12,-110, -94; /M: SY='W'; M= -30, 11, -28, -11, -54, -55, 47, -12, 9, 5, -33, 6, -12, 17, 51, 13, -90, -94, 79, 3; /M: SY='C'; M= -41, 97,-112,-107, -21,-111,-112, -16,-105, -26, -77,-104,-111,-108,-107, -51, -84, 90,-117, -93; /M: SY='W'; M=-104,-123,-129,-111, 50,-105,-124, -95,-103, -93, -97,-122,-110,-104,-106,-110,-112, -24, 173, -36; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='V'; M= -10, -15, 3,-102, -48,-110,-104, 60,-100, -72, -74,-101,-106,-101, -34, -94, -29, 77,-104, 36; /M: SY='P'; M= -20,-113, -89, 35,-110, -23, -96, -96, -24,-104, -33, -95, 106, 0, -15, -19, -87, 7,-109,-105; /M: SY='D'; M= -45,-107, 101, -7, -7, -94, 60,-107, -43, -45,-101, 13, -98, -83, -91, 17, -85, -55,-122, -91; /M: SY='P'; M= 10,-107, 8, 39,-111, -53, -91,-105, 19,-108, -99, -7, 87, -29, -88, 36, -20,-102,-110,-104; /M: SY='E'; M= -46,-106, 38, 61,-106, -37, -24,-103, 60, -19, -95, 34, -94, 18, -19, -85, -19, -43,-111, -97; /M: SY='E'; M= -3,-106, 27, 79,-106, 6, 13,-101, -41, -10, -94, 6, -93, 24, -15, -27, -42, -34,-111, -98; /M: SY='G'; M= 41,-100, -90, 3,-105, 63, -5, -96, -91, -99, 10, -13, -97, 16, -96, 32, -85, 10,-108, -99; /M: SY='W'; M=-104,-116,-116,-106, 72,-107, -96, -91,-100, -86, -89,-111,-111, 3,-100,-104,-105, -99, 148, 83; /M: SY='I'; M= -43, 26, -31, 24, -88,-111, -6, 65, -13, 0, -75, -97,-102, 10, -19, -94, -41, 51,-109, -91; /M: SY='K'; M= 17, 13, 30, 9,-104, 12, -4,-100, 57, -8, -2, -32, -6, -20, -27, 17, -86, -71,-109, -97; /M: SY='G'; M= 67, -10, -96, -97,-108, 77,-100,-104, -96,-105, -98, -85, -98, -93,-102, 5, -88, -41,-106,-104; /M: SY='E'; M= -47,-106, -1, 84, -38,-100, -88, -82, 36, -71, 10, -25, -91, -73, -7, 7, 12, -24, 34, -95; /M: SY='I'; M= -90,-102,-111, -16, -80,-117,-111, 81,-105, 24, -67,-107,-106,-103,-107,-101, -86, 65,-108, -88; /M: SY='Q'; M= -51,-102, -95, -25, -92,-105, -5, 24, 41, 11, 9, -89, -99, 52, -34, -86, 48, 36,-108, -90; /M: SY='S'; M= -42,-103, 21, 51,-109, -15, -87,-108, 58,-108,-100, -7, -92, -41, -26, 65, -27,-102,-110, -98; /M: SY='D'; M= -37, -12, 38, 38, -97,-100, 11, 32, -19, -31, -88, 18, -45, -82, 29, -2, 34, -24,-111, -16; /M: SY='E'; M= -36,-105, 28, 48, -42, 3, -30, -50, 25, -42, -94, 32, -2, -8, -20, 11, -5, -42,-103, 31; /M: SY='G'; M= -21,-105, 15, 26, -6, 70, -94, -50, 0, -67, -98, 0, 16, -87, -42, -4, -20, -33,-106, -99; /M: SY='D'; M= -89,-107, 66, 42, -51, 43, -88, -59, 21, -59,-100, 17, -16, 11, -37, -23, -27, -54,-112, -99; /M: SY='K'; M= -34,-106, 30, 54,-108, 28, -87, -59, 60,-106, -99, 23, -94, 0, -77, 5, -40, -52,-108, -42; /M: SY='V'; M= 13,-100, 31, -42, 9, 13, -98, 4, -32, -14, -82, -8,-103, -19, -59, -12, -41, 60,-107, -28; /M: SY='T'; M= -87,-100, -40, 21, -96, -45, 14, -15, 47, -52, -39, -84, -95, -83, 3, -48, 74, 28, 6, -29; /M: SY='V'; M= 7, -3,-107,-102, -1,-107, -13, 32, -38, -49, -76,-100,-105, -34,-101, -24, -8, 81,-105, 19; /M: SY='K'; M= -90,-104, -36, 46, 1, -62, 37, -51, 52, -1, -17, -28, -98, 10, -27, -35, -14, 39,-107, -88; /M: SY='T'; M= -46, 44, -98, -20, -88, -55, -96, -18, -90, 47, 14, -93, 7, 4, 10, -42, 65, -12,-109, -92; /M: SY='E'; M= 6,-101, 7, 59, -95, -69, -29, -86, -50, 24, -85, -41, -39, 7, -39, -3, 42, 7,-109, -30; /I: I=-20; MI=0; MD=-51; IM=0; DM=-51; /M: SY='D'; M= -35,-105, 81, 18,-112, -10, -21,-111, -32,-112,-105, 62, -98, -11, -56, 30, -10,-107,-121, -70; D=-20; /I: I=-20; MI=0; MD=-51; IM=0; DM=-51; /M: SY='G'; M= -25,-106, 20, 6,-109, 88, -93,-115, -90,-112,-103, 23, -97, -22, -19, -21, -54,-109,-106, -22; /M: SY='K'; M= 7,-104, -38, 25,-105, -97, -88, -99, 77, -39, -93, 22, -27, 7, 23, -31, 6, -23,-107, -96; /M: SY='T'; M= -88,-101, 30, 22, -96,-103, -38, 25, 26, -31, -25, -84, -96, -24, -21, -17, 68, 27,-113, -94; /M: SY='V'; M= -59,-101, -33, -37, -13,-112,-102, 30, -34, 39, -71,-103,-108, -19, 12, -98, -87, 72,-106, -26; /M: SY='T'; M= -61,-100, 9, 6, -43, -73, -93, -13, 27, -61, 8, -37, -2, 7, -14, 4, 73, 20,-112, -94; /M: SY='V'; M= 13, -6,-108,-103, -82,-108, -16, 38, -37, -10, -74,-103,-106,-100, -34, -93, -31, 81,-106, 22; /M: SY='K'; M= -61, -38, 19, 12,-106, -41, 3, -55, 72, -43, -96, 57, 17, -76, 5, 0, -30,-102,-111, -97; /M: SY='E'; M= -89,-105, -30, 57, -31, -43, -91, 17, 32, -5, -6, -41, 28, -81, -21, 13, 18, -19,-105, -17; /M: SY='D'; M= -49, -13, 92, 47, -43, -94, -84,-111, 4,-109,-104, 17, -95, 9, -86, 21, -50,-106,-117, -38; /M: SY='Q'; M= -63,-107, 67, 28, -50, -97, -11, -58, 18, -41, -94, 17, -16, 73, -45, -9, -4, -22,-113, -95; /M: SY='V'; M= -17, -20,-111,-103, -9,-112,-106, 58, -31, 39, -25,-105, -46, -6,-102, -98, -58, 61,-106, -87; /M: SY='Q'; M= -95,-106, -14, 21, 66,-103, 8, -89, -50, -16, -3, 23, -37, 71, -22, -89, -9, -33, -89, 47; /M: SY='P'; M= -45,-110, -23, 1,-109, -34, -88,-105, 33,-108, -19, 39, 88, 39, -1, 10, -86,-105,-108, -27; /M: SY='M'; M= 22,-101, -13, 1, -94, -98, -87, -81, 27, -52, 100, -30, -98, 37, 12, -38, -19, 11,-105, -15; /M: SY='N'; M= -93, -6, 44, -9,-106, -46, -78,-103, -2, -34, -98, 113,-101, -80, -39, -79, -81, -48,-122,-100; /M: SY='P'; M= -4,-113, 16, -21,-110, -97, -96, -39, -89,-105, -14, -15, 113, -18, -41, -88, -3, -28,-111,-106; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 120 in 120 different sequences |
| Number of true positive hits | 120 in 120 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | Myosin N-terminal SH3-like |
| Version [info] | 3 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
120 sequences
MY18A_HUMAN (Q92614), MY18A_MOUSE (Q9JMH9), MY18A_RAT (D3ZFD0), MYH10_BOVIN (Q27991), MYH10_HUMAN (P35580), MYH10_MOUSE (Q61879), MYH10_RAT (Q9JLT0), MYH11_CHICK (P10587), MYH11_HUMAN (P35749), MYH11_MOUSE (O08638), MYH11_RABIT (P35748), MYH13_CANLF (Q076A3), MYH13_HUMAN (Q9UKX3), MYH14_HUMAN (Q7Z406), MYH14_MOUSE (Q6URW6), MYH15_HUMAN (Q9Y2K3), MYH16_CANLF (F1PT61), MYH1B_CHICK (P02565), MYH1_BOVIN (Q9BE40), MYH1_CANLF (Q076A6), MYH1_HORSE (Q8MJV0), MYH1_HUMAN (P12882), MYH1_MOUSE (Q5SX40), MYH1_PIG(Q9TV61), MYH2_BOVIN (Q9BE41), MYH2_CANLF (Q076A7), MYH2_HORSE (Q8MJV1), MYH2_HUMAN (Q9UKX2), MYH2_MOUSE (G3UW82), MYH2_PIG(Q9TV63), MYH3_HUMAN (P11055), MYH3_MOUSE (P13541), MYH3_RAT(P12847), MYH4_CANLF (Q076A5), MYH4_HUMAN (Q9Y623), MYH4_MOUSE (Q5SX39), MYH4_PIG(Q9TV62), MYH4_RABIT (Q28641), MYH4_RAT(Q29RW1), MYH6_HUMAN (P13533), MYH6_MESAU (P13539), MYH6_MOUSE (Q02566), MYH6_RAT(P02563), MYH7B_HUMAN (A7E2Y1), MYH7B_MOUSE (A2AQP0), MYH7_BOVIN (Q9BE39), MYH7_CANLF (P49824), MYH7_HORSE (Q8MJU9), MYH7_HUMAN (P12883), MYH7_MESAU (P13540), MYH7_MOUSE (Q91Z83), MYH7_PIG(P79293), MYH7_RAT(P02564), MYH8_CANLF (Q076A4), MYH8_HUMAN (P13535), MYH8_MOUSE (P13542), MYH9_CANLF (Q258K2), MYH9_CHICK (P14105), MYH9_HUMAN (P35579), MYH9_MOUSE (Q8VDD5), MYH9_RAT(Q62812), MYO10_ARATH (F4IVR7), MYO11_ARATH (F4HWY6), MYO12_ARATH (F4IRU3), MYO13_ARATH (F4IUG9), MYO14_ARATH (F4JM19), MYO15_ARATH (Q0WPU1), MYO16_ARATH (Q9M2K0), MYO17_ARATH (F4K5J1), MYO1_ARATH (Q9LHE9), MYO1_CAEEL (P02567), MYO1_YEAST (P08964), MYO2A_NAUCA (Q875X3), MYO2B_NAUCA (Q875X4), MYO2_ARATH (F4K0A6), MYO2_CAEEL (P12845), MYO2_LACK1 (Q875Q8), MYO2_SACU7 (Q876G9), MYO2_SCHPO (Q9USI6), MYO2_YEAST (P19524), MYO3_ARATH (F4I507), MYO3_CAEBR (Q60LV4), MYO3_CAEEL (P12844), MYO3_SCHPO (O14157), MYO4_ARATH (F4JIU4), MYO4_CAEEL (P02566), MYO4_YEAST (P32492), MYO51_SCHPO (O74805), MYO52_SCHPO (O94477), MYO5A_CHICK (Q02440), MYO5A_HUMAN (Q9Y4I1), MYO5A_MOUSE (Q99104), MYO5A_RAT (Q9QYF3), MYO5B_HUMAN (Q9ULV0), MYO5B_MOUSE (P21271), MYO5B_RAT (P70569), MYO5C_HUMAN (Q9NQX4), MYO5_ARATH (Q39160), MYO6_ARATH (Q9LKB9), MYO6_BOVIN (E1BPK6), MYO6_CHICK (Q9I8D1), MYO6_HUMAN (Q9UM54), MYO6_MOUSE (Q64331), MYO6_PIG(Q29122), MYO7_ARATH (F4I5Q6), MYO8_ARATH (F4I460), MYO9_ARATH (F4HXP9), MYOH_DICDI (P54696), MYOJ_DICDI (P54697), MYOM_DICDI (Q9TW28), MYS2_DICDI (P08799), MYS9_DROME (Q01989), MYSA_DROME (P05661), MYSN_ACACA (P05659), MYSN_DROME (Q99323), MYSS_CHICK (P13538), MYSS_CYPCA (Q90339), MYS_ARGIR (P24733), OP1_MAIZE (K7U9N8), Y4A0_ENCCU (Q8SS35)» more
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| PDB [Detailed view] |
173 PDB
1B7T; 1BR1; 1BR2; 1BR4; 1D0X; 1D0Y; 1D0Z; 1D1A; 1D1B; 1D1C; 1DFK; 1DFL; 1FMV; 1FMW; 1G8X; 1I84; 1JWY; 1JX2; 1KK7; 1KK8; 1KQM; 1KWO; 1L2O; 1LVK; 1M8Q; 1MMA; 1MMD; 1MMG; 1MMN; 1MND; 1MNE; 1MVW; 1O18; 1O19; 1O1A; 1O1B; 1O1C; 1O1D; 1O1E; 1O1F; 1O1G; 1OE9; 1QVI; 1S5G; 1SR6; 1VOM; 1W7I; 1W7J; 1W8J; 1W9I; 1W9J; 1W9K; 1W9L; 1YV3; 2AKA; 2BKH; 2BKI; 2DFS; 2JHR; 2JJ9; 2MYS; 2V26; 2VAS; 2VB6; 2W4A; 2W4G; 2W4H; 2W4T; 2W4V; 2W4W; 2X51; 2X9H; 2XEL; 2XO8; 2Y0R; 2Y8I; 2Y9E; 3BZ7; 3BZ8; 3BZ9; 3DTP; 3J04; 3L9I; 3MJX; 3MKD; 3MNQ; 3MYH; 3MYK; 3MYL; 4AE3; 4ANJ; 4DB1; 4DBP; 4DBQ; 4DBR; 4P7H; 4PA0; 4PD3; 4PJK; 4ZG4; 4ZLK; 5HMP; 5I4E; 5JLH; 5M05; 5N69; 5N6A; 5O2L; 5T45; 5TBY; 5W1A; 6BIH; 6BNP; 6BNQ; 6BNV; 6BNW; 6FSA; 6QDJ; 6X5Z; 6YSY; 6Z2S; 6Z7T; 6Z7U; 7B1A; 7DHW; 7JH7; 7MF3; 7NEP; 7PLT; 7PLU; 7PLV; 7PLW; 7PLX; 7PLY; 7PLZ; 7PM0; 7PM1; 7PM2; 7PM5; 7PM6; 7PM7; 7PM8; 7PM9; 7PMA; 7PMB; 7PMC; 7PMD; 7PME; 7PMF; 7PMG; 7PMH; 7PMI; 7PMJ; 7PML; 7QIN; 7QIO; 7YV9; 8ACT; 8EFD; 8EFE; 8EFH; 8EFI; 8ENC; 8EXW; 8G4L; 8Q6T; 8QYP; 8QYQ; 8QYR; 8QYU; 8SYF; 8W41; 9F6C » more |