PROSITE entry PS51846
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General information about the entry
| Entry name [info] | CNNM |
| Accession [info] | PS51846 |
| Entry type [info] | MATRIX |
| Date [info] |
20-DEC-2017 CREATED;
20-DEC-2017 DATA UPDATE; 27-MAR-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51846 |
| Associated ProRule [info] | PRU01193 |
Name and characterization of the entry
| Description [info] | CNNM transmembrane domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=184; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=179; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.7000365; R2=0.0064028; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1063; N_SCORE=9.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=594; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-70; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='M'; M= -14, 34, 39, 12, -8, -29,-146, -33,-145, -58, 54, -10, -53, -7, -39, 22, -34, -32,-165, -29; /M: SY='D'; M= -4,-159, 36, -21, 11, 0, -9, 14, -34, 8,-141, -16,-158,-146,-152, 30,-142, -47,-161, -22; /M: SY='M'; M= 6,-152,-154,-148, -13, -12,-148, -18, -8, 23, 77,-146, 28,-145,-148, -4, 34, -13,-157,-141; /M: SY='P'; M= -36,-155, 36, 8,-148, -40,-141,-143,-138, -28, 43, -51, 75,-137, -28, 24, 30, -32, 3, 0; /M: SY='M'; M= -15,-149, -11, -40, 16, -3,-146, 22, -45, 40, 53,-146, -5,-144,-148,-141, 12, 24, 44, -17; /M: SY='W'; M= -45,-153,-152, -37, 39, 10,-147, 11,-144, -4,-131,-146, -38,-145, -20, -24, 33, 12, 114, 44; /M: SY='T'; M= 8, 15, 3, -2, -22,-149, -1, 16,-142, 29, -4, -14, 14,-140,-146, -28, 43, 2, 39, 4; /M: SY='W'; M= -38, 11,-138, 19,-136,-147, 23, 7, -39, -8, 52, 14,-147, 69, -34, 6, 4, -62, 69, 33; /M: SY='I'; M= -13, -1,-158,-154, 2, -3,-151, 59,-152, 48, 37,-151,-154,-149,-153,-144, -20, 26, 18, -21; /M: SY='L'; M= 33, -28,-158,-152, -26, -29,-151, 59,-152, 64,-115,-152, -19,-148,-153,-143,-137, -13,-150,-135; /M: SY='I'; M= 18, 19,-155,-152, 20, 11,-152, 57,-150, 28,-122,-147,-153,-148,-153, -9, -20, 38,-151,-134; /M: SY='I'; M= 24, 32,-154,-151, 36,-150,-150, 72,-149, 26,-121, -11,-153,-147,-152, 21,-133, -9,-149,-131; /M: SY='I'; M= 41, 40,-156,-152, 44, -30,-151, 47,-150, 40, -46,-149,-154,-149,-152, -56, -31, 11,-147,-131; /M: SY='I'; M= 23, 11,-158,-154, 33, -2,-152, 47,-152, 47,-119,-151,-155,-150,-153,-142,-136, 42,-149,-131; /M: SY='L'; M= -9, 67,-159,-152,-124,-157,-147,-115,-153, 88, -7,-155,-160,-148,-152, -26,-138, -42,-152,-135; /M: SY='I'; M= 3,-148,-158,-154, -27,-159,-154, 72,-152, 50,-115,-152,-154,-150,-154,-143, 9, 41,-152,-134; /M: SY='L'; M= 41, 51,-153,-150, 5, 23,-149,-122,-149, 53,-123,-146,-154,-146,-151, -18, -58, 32,-152,-137; /M: SY='W'; M= -38, 8,-159,-155, 37, 8,-150, 25,-153, 63, 14,-152,-157,-149,-153, -38,-139, 13, 64,-127; /M: SY='S'; M= 38,-142,-135,-137,-150, 3, 9,-147,-136, -44,-142, 11,-143,-131,-141, 88, 38,-139,-159,-144; /M: SY='A'; M= 85,-144,-144,-143,-156, 72,-148,-151,-143,-151,-144,-134,-144,-140,-148,-121, -31,-140,-153,-151; /M: SY='F'; M=-143,-148,-161,-156, 75,-162,-146, 27,-153, 51, -20,-155,-159,-153,-152,-149, -27, 41,-136, 33; /M: SY='F'; M= -4, 50,-162,-157, 109,-156,-145, -31,-153, -39, 54,-152,-160,-157,-152,-146,-141, 3,-129, 0; /M: SY='S'; M= 8,-142,-139,-138,-147,-134,-142,-133,-136,-143,-139,-129,-144,-132, -13, 96, 25, 42,-161,-143; /M: SY='G'; M= 58, -1,-145,-147,-151, 80,-145,-147,-144, -45, 56,-134,-146,-140,-149, -3,-137,-141,-153,-148; /M: SY='L'; M= 37,-145,-151,-147, -12, -36,-143, 19,-146, 53, 42,-144,-151,-141,-148, 42, -44, -44,-147, 16; /M: SY='E'; M=-137,-152, -11, 95,-152,-148,-131,-153, -26,-151,-145, 34,-137, 3, -34,-128, 58,-147,-157, 0; /M: SY='F'; M= -11,-146,-155,-151, 60,-156, 13, 32,-150, 54, 12,-147,-153,-148,-150,-141, 45, -5,-145,-124; /M: SY='A'; M= 71,-144,-142,-142,-154, 65,-146,-149,-142,-151,-144,-132,-144,-137,-147, 51,-130, -32,-154,-150; /M: SY='L'; M= -4, 14,-158,-151, 14,-158,-147, 62,-150, 67, -7,-153,-156, 21,-150,-147,-139,-114,-145, 1; /M: SY='M'; M= -15,-146,-153,-146, 25,-152,-141, -8,-144, 9, 109,-144,-150, 21,-144, -21, 33, 36,-151,-129; /M: SY='S'; M= 41,-144,-136,-133,-152, 0, 37,-150, 18,-151,-143,-126,-142, -6, -12, 78, 31,-142,-158,-142; /M: SY='L'; M= -15, -2, -16,-148, 30,-155,-147, 11,-150, 71, -33,-150, -24, -25,-150, 0,-136, 16,-148,-130; /M: SY='W'; M= -29,-151, 45,-131,-148, -15,-136,-149,-125, -19,-143, 39, -25,-130, 64, 39, 34,-146, 69,-140; /M: SY='P'; M= -11,-157, 5, -42,-149, -29,-140, -16, 42, 1, 13,-138, 82,-131, 47, -15,-136,-142,-154,-146; /M: SY='Y'; M= 12,-149, 11, -26, -15,-146,-139, 2,-141, -9, 27, -19,-150, 29,-143, 31,-132, 47, 39, 50; /M: SY='R'; M=-140,-157, 29, 62,-152,-150, -4,-155, 50, -45,-143,-129,-143,-119, 77, -28, -19,-151,-155, -22; /I: I=-10; MD=-26; /M: SY='L'; M=-144,-151,-165,-158,-124,-166,-156, 39,-157, 74,-114,-162,-161,-153,-157,-155,-141, 44, 56,-134; D=-10; /I: I=-10; MD=-26; /M: SY='E'; M=-141,-159, 36, 63,-161,-148, 12,-161, 22,-157,-148, 9,-145, 45, 57, 11,-138,-157,-161,-146; D=-10; /I: I=-10; MI=0; MD=-26; IM=0; DM=-26; /M: SY='Q'; M= -8,-153,-142, 23, -35,-153, -8, 18,-138, 0, 13, 7,-151, 67,-141, -37, -25, 37,-151, 27; D=-10; /I: I=-10; DM=-26; /M: SY='L'; M=-145,-151,-158,-154,-122,-162,-143, -10,-150, 76, 16, -11,-161,-147, -22,-150, -18, 14,-146, 46; D=-10; /I: I=-10; DM=-26; /M: SY='Q'; M= 43,-152, -16, -38,-147,-147, 12, 41, 2,-136, -4,-139,-149, 48, 6, 1, -20, 21,-158,-143; D=-10; /I: I=-10; DM=-26; /M: SY='E'; M= -10,-156, -20, 51,-155, -35,-136, -25, 48, -26,-142, 28,-146, 40, 41,-134, -12,-147,-158,-147; D=-10; /I: I=-10; DM=-26; /M: SY='S'; M= 3, 29, 13, 29,-160, -5,-141,-158, 11,-157,-150,-131,-146, 28, -31, 68, -2,-150,-163,-150; D=-10; /I: I=-10; DM=-26; /M: SY='G'; M=-134,-158, -25, 6,-164, 92, 1,-169, -31,-165,-155, 27,-149, 1,-148,-132,-146,-164,-159,-155; D=-10; /I: I=-10; DM=-26; /M: SY='N'; M= -18,-151, 28, -52,-158, -32,-138,-155, 6,-158,-150, 67, -11,-133, -1, 45, 51,-149,-168,-150; D=-10; /I: I=-10; DM=-26; /M: SY='P'; M= -2,-156, 28, 37,-155,-146,-139, -12, 38,-149, 8, -30, 64, -18, 16, 3, -21, -43,-159,-148; D=-10; /I: I=-10; DM=-26; /M: SY='A'; M= 45,-150,-136, -62,-156, 22, -19,-154, 32,-153,-144, 24,-146, 36, 38, 27, 5,-146,-157,-146; D=-10; /I: I=-10; DM=-26; /M: SY='A'; M= 67,-149, 29, 61,-156, -8, -30,-151, -1, -51,-145,-134, -23,-129,-138, -27, -25,-143,-158,-149; D=-10; /I: I=-10; MI=0; MD=-26; IM=0; DM=-26; /M: SY='K'; M=-145,-160,-142,-131,-153, -30,-139, 10, 79, -33, 12, -16,-151, 28, 63,-141,-142,-145,-156,-145; D=-10; /I: I=-10; DM=-26; /M: SY='K'; M= 42, 15,-144, -39,-149,-146,-144, -6, 54, 0,-136, -42, -13, 15, 25, -5,-136, -10,-157,-146; D=-10; /I: I=-10; DM=-26; /M: SY='H'; M= 44, -14, -37,-142, -14, -37, 54, -32,-140, 7,-132, -14,-153, 21, 6, -37, -29, 24,-153, 23; D=-10; /I: I=-10; DM=-26; /M: SY='A'; M= 69,-149,-143, 8,-150,-142, 30,-141, -1, 6,-136,-140, -10, -18, 22, -63, -2, -29,-158,-145; D=-10; /I: I=-10; DM=-26; /M: SY='K'; M= 19,-155,-138, -51,-154, -31, -5,-153, 75,-149, 36, -13,-147, -6, 72, -64,-138,-148,-154,-143; D=-10; /I: I=-10; DM=-26; /M: SY='R'; M= -11,-152, -26,-141,-133,-157,-143, 16, 30, 50, 8,-146,-154,-136, 53,-144,-139, 21,-151, -4; D=-10; /I: I=-10; DM=-26; /M: SY='I'; M= -17,-152,-152,-148,-132,-155,-147, 71,-143, -7, 16, -16, -14, 17, 2, 2, -41, 33,-150, 26; D=-10; /I: I=-10; DM=-26; /M: SY='E'; M= -6,-151, -19, 57, 44,-149, -3,-138, -26, 14, 37, 7,-147, -20, -38, -8, 28,-138,-149, -16; D=-10; /I: I=-10; DM=-26; /M: SY='P'; M= -1,-160, 33,-131,-157,-146, 81,-153, 2, -45, 8, 25, 83, -3, -2,-138,-139,-154,-165,-143; D=-10; /I: I=-10; DM=-26; /M: SY='P'; M= -30,-154,-159,-150, 25,-159,-152, 19,-147, 46, -3,-156, 61,-149, 9,-149,-140, 38,-152,-136; D=-10; /I: I=-10; DM=-26; /M: SY='R'; M=-141,-156, 52,-132,-155, 6,-138, -47, -30, -58,-144, 39, -6, 14, 62, -25, 8, 10,-164,-147; D=-10; /I: I=-10; DM=-26; /M: SY='R'; M=-143, -1,-137, 21, -16, 6,-138, -30, 41,-152, 7, 27,-151, -17, 75, -45, -40,-151,-157,-145; D=-10; /I: I=-10; DM=-26; /M: SY='Y'; M= -9,-157,-147,-144, 56,-152, 27,-142, 24, 3,-136, 38, -26, -36, 27,-143,-143,-145, 45, 58; D=-10; /I: I=-10; DM=-26; /M: SY='Q'; M= -30,-155,-152,-146, -17, 35,-145, 4,-146, 49,-127,-145,-156, 61,-147, 0,-142, -26,-150, 16; D=-10; /I: I=-10; MI=0; MD=-26; IM=0; DM=-26; /M: SY='H'; M= -9,-150,-133,-137,-156, 22, 71,-156,-135,-156,-146, 59, -11, 18, -20, 58, 22,-151,-165,-143; D=-10; /I: I=-10; DM=-26; /M: SY='W'; M= 35, 20,-150, -25, 23,-150, -5, 15,-142, 13, 9,-145,-152, 39, -34, -38, 20, -33, 50, 14; D=-10; /I: I=-10; DM=-26; /M: SY='C'; M= -5, 71,-158,-154,-135, -38,-154, 23,-150, 46,-123,-151,-158,-150, -20, -6, -22, 47,-160,-142; D=-10; /I: I=-10; DM=-26; /M: SY='L'; M=-144,-151,-158,-147,-128,-163,-147, -23,-149, 81,-114,-156,-160, 60,-148,-150,-141, 25,-153,-136; D=-10; /I: I=-10; DM=-26; /M: SY='C'; M= -38, 84,-154,-155, -14, -28,-154, 44,-152, 24,-127, 11,-158,-152,-155, -29, 10, 39,-160,-141; D=-10; /I: I=-10; DM=-26; /M: SY='T'; M= 9,-144,-140,-143, -35, 55,-145,-140,-140, -19, -1,-129,-143,-139,-146, 39, 80, -32,-156,-143; /M: SY='I'; M=-140,-148,-151,-151, -12,-157,-147, 61,-146, 58,-116, 32,-154,-146, -15,-142, 27, 19,-153,-133; /M: SY='L'; M= 5,-144,-145,-146,-131,-148,-144, 24,-144, 64,-120, 33,-150,-142,-147, 3, 61,-121,-155,-137; /M: SY='L'; M= -34,-148,-159,-154, -21,-160,-151, 59,-153, 73,-112,-154,-156,-149,-153, -22, -19, 15,-150,-132; /M: SY='C'; M= -20, 77,-150,-151, 17, 56,-150, -3,-148, 13, -4,-139,-151,-147,-152, -8, 26, 15,-153,-139; /M: SY='N'; M= 20,-147,-122, -19,-151, 28,-128,-153,-129,-156,-146, 108,-148, -19, -22, 8,-128,-151,-160, -1; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='W'; M= 28, 6,-157,-152, -16, -15,-155, 58,-150, -13, 11,-149,-152,-148,-152, -6,-133, 60, 62,-134; /M: SY='L'; M= 11,-146,-155,-150, 11, -15,-148, 23,-149, 50, 48,-147,-153,-146,-150, -10, 11, 40,-151,-133; /M: SY='A'; M= 64, 6,-148, -27, -12, 41,-152, 17,-145,-134,-133,-141,-148,-144,-150,-130, -39, 52,-154,-143; /M: SY='N'; M=-133,-148, -19, 41,-148, 7,-135,-138,-132, -41, 54, 66, -13, 3,-139, 36, 29, 9,-161,-144; /M: SY='A'; M= 60,-145,-136, 35,-147,-138,-142, -9,-136, -17, 5, 7, 14,-133,-142, 36, 29, -12,-157,-145; /M: SY='T'; M= 47,-144,-143, -24,-138, -5,-146, 20,-142, 19,-129,-137, -10,-140,-147, -10, 69, -32,-153, -2; /M: SY='C'; M= -16, 60,-157,-152, 38, -54, 12, 24,-152, 60,-118,-150,-157,-149,-152, 1,-136, 26,-149,-129; /M: SY='T'; M= 15,-148,-136, 26, 23, -47,-142,-139, -27,-143,-140,-134, 58, -20, -18, 30, 63, -1,-154,-140; /M: SY='I'; M= -33,-152, -24, -51,-133, -13,-146, 51, 13, 39,-123,-145, 31,-140, 22,-142, -35, 20,-151, -4; /M: SY='L'; M= 26, -21,-155, -24, 36, -37,-145, -20,-147, 62, 14,-152,-155,-145, -32,-143,-138, 13, 22, 15; /M: SY='L'; M= 16,-148,-156,-150, 47, -4,-145, 0,-147, 65, 40,-150,-156, -7, -18,-144,-139, -14,-144,-127; /I: I=-9; MD=-22; /M: SY='H'; M= 2,-155, 73, -35,-147, -60, 82,-149,-135, -46, 19, -18,-149, -2, 5, -26, 3, -34,-162, 24; D=-9; /I: I=-9; MD=-22; /M: SY='Y'; M= 18,-155, 9, -4, -21, -7, 11,-150, 10,-150,-143, -29, 34, 28, 18, 20, -62, -31,-149, 43; D=-9; /I: I=-9; MD=-22; /M: SY='L'; M= -4, -7,-156,-153, 24, -34, 37, 42,-152, 58,-120,-149,-156,-148,-153, -11, 2, -28,-152,-132; D=-9; /I: I=-9; MD=-22; /M: SY='F'; M= 11,-151,-159,-156, 79, -6,-147, 22,-153, 23, 12,-151,-158,-152,-153, -24, -46, -8,-137, 31; D=-9; /I: I=-9; MI=0; MD=-22; IM=0; DM=-22; /M: SY='G'; M= -35,-165,-151,-159,-169, 68,-156,-165,-155,-168, -15, 39, 27,-154,-162, -11, -26, -28,-171,-166; D=-9; /I: I=-9; DM=-22; /M: SY='E'; M=-141,-160, 28, 60, 9, -24, -23,-155,-136, -64,-150, -24, 59, 2,-144, 25, 3,-154, 43,-144; D=-9; /I: I=-9; DM=-22; /M: SY='W'; M= 46,-155, -4, -37,-148, 57,-148,-150,-143, 3,-143,-140, -16, -7, -14, -41, -45,-147, 59, -4; D=-9; /I: I=-9; DM=-22; /M: SY='W'; M= -4,-155,-160,-156, -12, 16,-154, 31,-154, 42,-128,-153,-158,-150,-156, 8,-142, 6, 94, 0; D=-9; /I: I=-9; MI=0; MD=-22; IM=0; DM=-22; /M: SY='L'; M= -37,-152,-161,-155, 29, -29,-149, 31,-154, 46, 24,-156, -27, -25,-154,-149,-140, 45,-145, 34; D=-9; /I: I=-9; DM=-22; /M: SY='A'; M= 73,-147, -23,-139,-156, 7,-146, -35, -23,-151,-144, 7, 15,-138,-145, 40, -21, -50,-159,-151; D=-9; /I: I=-9; DM=-22; /M: SY='F'; M= 30,-150,-163,-156, 69,-156,-154, 27,-154, 26, 13,-156,-158,-154,-155,-146,-141, 34, 64,-123; D=-9; /I: I=-9; DM=-22; /M: SY='V'; M= 48,-148,-154, -30, -28, -6,-154, 21,-150, 31,-126,-150,-154,-147,-153, -29,-136, 54,-157,-141; D=-9; /I: I=-9; MI=0; MD=-22; IM=0; DM=-22; /M: SY='I'; M= -15,-151, -18,-153,-130, -61,-157, 68,-153, 28, -15,-152,-155,-150,-155, -18,-136, 55, 64,-135; D=-9; /I: I=-9; DM=-22; /M: SY='S'; M= -13, -3,-151,-148,-140, -8,-148, -8,-147, 21, 43,-142, -9,-142,-150, 67,-130, 41,-160,-143; D=-9; /I: I=-9; MI=0; MD=-22; IM=0; DM=-22; /M: SY='T'; M= 16,-142,-141,-141,-146, -17,-148,-131,-139,-139,-137,-131,-143, -4,-145, -8, 101, 34,-164,-145; D=-9; /I: I=-9; DM=-22; /M: SY='F'; M= 11, 1,-151,-149, 47, -3,-147, -4,-147, 12, -16,-142,-152,-146,-150, 36, 28, 29,-146, 13; D=-9; /I: I=-9; DM=-22; /M: SY='L'; M= 28, -7,-158,-153, -8, 15,-149, -23,-152, 67, 31,-152,-157,-148,-153,-143,-139, 16,-151,-136; D=-9; /I: I=-9; DM=-22; /M: SY='I'; M=-139, 16,-153,-151, 26,-156, 61, 64,-149, 38, -9, -27,-154,-145,-150, 18,-134, 26,-152,-128; /M: SY='V'; M=-139,-147,-163,-156, 37,-162,-153, 25,-154, 57, 13,-158,-158,-152,-153,-150,-136, 69, 36,-127; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='V'; M= -2,-146,-159,-154, -52,-158,-155, 54,-152, 38, 2,-154,-155,-150,-153, -38,-132, 76,-156,-136; /M: SY='F'; M=-145, 8,-163,-158, 105, -51,-148, -39,-155, 31, -13,-155,-161,-159,-153,-150,-140, 37,-131,-110; /M: SY='G'; M= 38, 54,-144,-149,-155, 89,-149,-153,-145,-154,-146,-131,-147,-144,-152, -44, 5, -27,-155,-153; /M: SY='E'; M=-138,-159, 36, 113,-161, -30,-131,-163,-120,-155,-151,-131,-135,-114, -17,-134,-138,-155,-159,-150; /M: SY='I'; M=-141,-150,-162,-157, -12,-164,-150, 79,-154, 45, 40,-155,-156,-150,-154,-150,-136, 39,-146, 24; /M: SY='I'; M= 21, -2,-156,-152, 6, -30,-153, 59,-150, 39, -20,-149,-152,-149,-153,-139, 22, 37,-152,-134; /M: SY='P'; M=-144,-169,-144,-133,-164,-146,-147,-151,-140,-162,-148,-151, 135,-144,-153,-141,-136,-157,-157,-161; /I: I=-45; MD=-115; /M: SY='K'; M= -4,-157,-136,-121,-157,-146,-133,-155, 88,-153,-141,-129,-145, 86, 27, -33,-137,-152,-150, -18; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='T'; M= 56,-142,-138,-138,-144,-136,-139, -32,-133, -50, 11, 17,-144,-133, 17, 48, 67,-132,-155, -1; /M: SY='V'; M= -36,-148,-160,-155, 8,-161,-153, 61,-153, 50,-114,-155,-156,-151,-154,-147, -34, 61,-149, -7; /M: SY='C'; M= 70, 108,-148,-146, -23, 37,-150,-147,-146,-146,-142,-138,-151,-145,-151, -3,-134, -32,-158,-149; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='S'; M= -27,-148,-144, -38,-139, -28,-143, 37,-135, -21, 38, -16,-148, -3, 35, 47, 9, 44,-157,-139; /M: SY='R'; M= -8,-155,-139,-128, -16,-148, 12, 10, 36, -61, -10, -10,-148, 64, 83, -37, -31,-140,-152,-137; /M: SY='Y'; M= -39,-154,-136,-139, -11, -36, 77,-142, 26, -61,-134, 60,-152,-132, -18,-135, -20, -34, 45, 94; /M: SY='P'; M= 55,-151,-141,-141,-156, 59,-146, -37,-141,-152,-144, 15, 76,-140,-149, -23, -36, -43,-155,-152; /M: SY='E'; M=-142,-153, -19, 71, -12,-157,-137, 10,-132, 57,-124,-143,-147, 22, 10,-142, -33,-130,-148, 4; /M: SY='A'; M= 67,-146,-137, -6,-150,-137, 35,-145, 15, -19, -1, 13, -31, 4, 33, 19, -44,-139,-156,-142; /M: SY='V'; M=-135, 15,-158,-154, -19,-161,-158, 65,-151, 0,-119,-150,-153,-152,-154,-141, 35, 78,-158,-136; /M: SY='A'; M= 73,-143,-144,-142,-147, 49,-146,-141,-142, 17,-136,-135,-146,-139,-147, 29, 5,-135,-153,-146; /M: SY='A'; M= 53, 1,-149,-141, -35, -39,-142,-128,-135, 30, 50,-142, -5, -10, 38, -9, -21, 7,-151, -21; /M: SY='R'; M= -31,-150,-142,-142, 16, -11, 19, -11, -19, 36,-128, 40, -31,-135, 43, 17, -35, -33, 13, 22; /M: SY='T'; M= -29,-145,-151,-150, 46, 9,-149, 17,-147, 27, -21,-142,-151,-147,-150, 18, 47, 44,-149,-130; /M: SY='A'; M= 56, -7,-147, -39,-138, -36,-149, 47,-144, 2,-127, 15,-150, -12,-148, -4,-132, 37, 41,-140; /I: I=-45; MD=-115; /M: SY='P'; M= -10, -3,-147,-143, 36, 17, -10, -40, 10, -31,-138, -14, 70,-142, -20, -51, -21, -24, 56, 36; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='P'; M= -15,-153,-156,-149, 37, -34,-151, 48,-150, 44,-122,-153, 75,-149,-154,-145,-137, 13,-148,-133; /M: SY='V'; M=-135,-146,-152,-148,-127,-156,-145, 10,-146, 41, 48,-146,-152, -4,-148, -20, 48, 61,-151, 27; /M: SY='R'; M= -16,-154,-144,-138,-131, -9, -1, 21, -1, -10,-130, -23,-152, 1, 75,-138, -40, -1,-140, 69; /M: SY='W'; M= -36,-151,-161,-154, 67, -37,-153, 37,-152, 40,-122,-155, 8,-152,-154, -47,-140, 30, 90,-120; /M: SY='F'; M= -30, 11,-157,-152, 79,-156,-145, 14,-151, 49, 32,-151, 14,-151,-151, -38, 5, -41,-138, -3; /M: SY='M'; M= -13,-148, -24,-145, -11,-148,-134, -25,-143, 19, 93,-142,-151, -24,-144, 42, -33, 11,-139, 70; /M: SY='W'; M= -51, 6,-151,-142, 35,-156,-140, 9, 39, 39, -21,-145,-154, -17, 27,-143, -12, -7, 54, 44; /M: SY='L'; M= -51,-148,-162,-156, -19,-163,-152, 65,-155, 74, -19,-157,-157,-150,-154,-151,-137, 24,-150,-131; /M: SY='F'; M= 13, 51,-152,-149, 64,-150,-145,-124,-147, 41, 50,-143,-152,-147,-149, -13, 58, -32,-146,-126; /M: SY='Y'; M= -48,-151,-152,-148, 66,-152,-134,-130, -37, 13, 35,-145,-154,-142, -22, -1, 33,-133, 73, 88; /M: SY='P'; M=-144,-169,-144,-133,-164,-146,-147,-151,-140,-162,-148,-151, 135,-144,-153,-141,-136,-157,-157,-161; /M: SY='I'; M= 0,-149,-161,-156, 43,-160,-154, 74,-154, 48,-115,-155,-156,-152,-155,-147,-136, 32,-146,-128; /M: SY='A'; M= 49, -2,-147,-144,-141, -5,-149, 40,-142, -16,-130,-138,-147,-140, -21, 43, 24, 30,-157,-142; /M: SY='W'; M= -10,-160,-156,-145, -1,-151,-140,-139, 5, 4, 5,-151,-155, -4, 28,-146,-147,-144, 139, 80; /I: I=-28; MD=-70; /M: SY='L'; M= -21,-172,-184,-177, 27,-182,-172, -22,-178, 54,-138,-181, -18,-175,-177,-173,-164, -35,-168,-150; D=-28; /I: I=-28; MD=-70; /M: SY='L'; M= -8,-171,-180,-176, 7, -38,-168, -27,-174, 39, 27,-174,-179,-171,-174,-166, -20, -32,-168, -5; D=-28; /I: I=-28; MI=0; MD=-70; IM=0; DM=-70; /M: SY='N'; M=-165,-176, -1, -26,-174,-168,-157,-163,-154, -50, 8, 65,-175, -7, -2, -51, -20, -4,-191,-170; D=-28; /I: I=-28; DM=-70; /M: SY='P'; M= 14,-157,-147,-141, -12, -17, -5, -46, -28, 17,-136, 8, 91,-143,-148, -31, -31,-142, 66, -2; D=-28; /I: I=-28; DM=-70; /M: SY='I'; M= -11,-148,-157,-153, -33,-157,-153, 75,-152, 55,-115,-151,-153,-148,-153, -1, -5, 18,-152,-134; /M: SY='S'; M= 46,-144,-141, -37,-146, 36,-143,-135,-140, -5, 9,-133,-145, -10,-144, 65, -11, 15,-156,-144; /M: SY='R'; M=-140,-153,-135,-128,-148, -59,-132, -37, 66, -6, 36, 45,-147, 40, 69,-134, 1,-143,-154,-140; /M: SY='L'; M= -31,-149,-154,-149,-128, -35,-148, 48, -31, 64, 11, -12, 14,-144, -19, -46,-136, 19,-153,-136; /M: SY='L'; M= -36,-147,-161,-155, 69,-161,-148, 14,-154, 76,-113,-156,-159,-152,-153,-150, -33, -4,-140,-121; /M: SY='D'; M= 4, -8, 71, -17, 7, 52,-138,-148, -37, -16, 19, 29,-146,-137,-143,-130, 17,-145,-158,-142; /M: SY='W'; M= -5, 26,-148,-139, 11, -24,-142, 22, 39, 8,-131,-141, 14, -24, 50, -28,-138, -33, 56, 19; /I: I=-22; MD=-55; /M: SY='M'; M= 6, -2,-151, -23, 25, -4, -14, 24, 10, 8, 46,-145,-154, -7, -18,-141, -32, 10,-146, 32; D=-22; /I: I=-22; MD=-55; /M: SY='L'; M= 8,-152,-152, -7, 39,-154,-147, -12, -28, 56, -8,-151, 40,-144, -15, -16, -33, -49,-149,-133; D=-22; /I: I=-22; MD=-55; /M: SY='G'; M= -18,-156,-140,-140,-159, 76, -3,-161, 50,-160,-149, 12, -10,-135, 20, -27,-141, -56,-156,-151; D=-22; /I: I=-22; MD=-55; /M: SY='H'; M= -45,-156, -2, 30, -10, -12, 37, -14, 25, 26,-132,-140, 16, 28, -17, -51,-140, 7,-156,-139; D=-22; /I: I=-22; MD=-55; /M: SY='E'; M= -48,-161, 33, 62,-163, 11,-140,-162, 44, -57,-152, -5, 11,-128, 9, -11,-141,-158,-163,-153; D=-22; /I: I=-22; MD=-55; /M: SY='H'; M=-152,-164,-156,-154,-149, -35, 52, 16,-151, 4, 8, 17, 32, -20, -7,-150, 8, 14,-169, -29; D=-22; /I: I=-22; MI=0; MD=-55; IM=0; DM=-55; /M: SY='D'; M= -29,-166, 37, 29,-170, 11,-149,-166, 11,-167,-160, -11,-157, -29, 22, 11, -40, -32,-173,-161; D=-22; /I: I=-22; DM=-55; /M: SY='T'; M= -34,-154, 31, 23,-150, -26,-145, -29,-139, -2, 9,-138, 38, 1, -39, 14, 42, 12,-163,-148; D=-22; /I: I=-22; DM=-55; /M: SY='V'; M= 24,-150, 6,-143, 29, -46,-146,-129, -31, -2, 22, -17, -24, -6,-147, 26, -18, 38,-153, -2; D=-22; /I: I=-22; DM=-55; /M: SY='H'; M= -31,-151,-150,-146, 11,-155, 65, 38,-140, 5, 36,-143,-153, -6, 13, -34, -33, 37,-142, 63; /M: SY='S'; M= -42,-144, -42, -4,-149, -61,-136,-146, -14, -38,-142, 46,-142,-128, 15, 74, 68,-140,-161,-144; /M: SY='R'; M=-138,-156, -22, 71,-154,-150,-134,-151, 3, -44,-143,-133, 34,-121, 75, 8, 8, -38,-157,-145; /M: SY='E'; M= 26,-152, 48, 81,-156, -39,-135, -22, -15, -51,-145, -29,-140, -3, -29, 19,-133,-144,-159,-147; /M: SY='E'; M=-139,-159, 42, 94,-161, -24,-132,-161, 30,-155,-149,-129, -16, 26, 17,-134,-138,-155,-158,-148; /M: SY='L'; M=-142,-148,-159,-152,-123,-163,-149, 49, 4, 81, -2,-155,-157,-146,-147,-151,-138, 10,-150,-133; /M: SY='R'; M=-140,-153, -25, -24, -26,-151,-135,-136, 48, 10, 17,-136, 14, -4, 62, -2, -17, 3,-146, 36; /M: SY='E'; M= 18, 16, -22, 59, 2,-146, 11, -22, -25, -25, 51,-135,-143, -10,-137, 21, 27, -17,-153, -14; /I: I=-42; MD=-106; /M: SY='M'; M= -41,-148, -20,-152, 14,-160,-146, 25,-152, 63, 91,-153,-156,-147,-151,-149, -35, 12,-150,-130; D=-42; /I: I=-42; MI=-106; MD=-106; IM=-106; DM=-106; /M: SY='V'; M= -10,-148,-160,-152, -14,-160,-153, 38,-150, 54,-116,-155,-157, -13, -22,-147,-136, 66,-154,-135; D=-42; /I: I=-42; DM=-106; /M: SY='R'; M= -16,-153, 45, 37,-150,-144, 29, -35, 18,-150,-144, -41,-143,-124, 58, 32, 26,-146, 38, -32; /M: SY='E'; M= 13,-151, 24, 72, -23, -2,-138, -21,-134, 23, 33,-136,-144, -16,-140, 4,-135, -16,-155,-141; /M: SY='H'; M= 24,-148, 8, -31,-149, 36, 81, 11,-138,-144, 13, -24,-144,-133,-142, 59, -4,-139,-160,-138; /I: I=-33; MI=0; MD=-84; IM=0; DM=-84; /M: SY='Y'; M= 34,-152, 31, 35, -15, 16, 9,-140,-139, 2, 22,-136,-148, 1,-142, -9, -45, -31,-148, 45; D=-33; /I: I=-33; DM=-84; /M: SY='Q'; M=-136,-155, -42, 46,-155, -24,-134,-151, 59, -17,-141, -11, 39, 65, -17, 18, -24,-149,-154,-145; /I: I=-38; MD=-97; /M: SY='N'; M= 10,-151, 5, 39,-143, 8, 12, -16, -48,-148,-143, 52,-146,-130, -15, 36, -18, -51,-151, 49; D=-38; /I: I=-38; MI=-97; MD=-97; IM=-97; DM=-97; /M: SY='G'; M=-131,-154, 17, 38,-160, 85,-143, -48, -26,-160,-152, -7,-144,-135,-145, 17, -40,-156,-157,-153; D=-38; /I: I=-38; DM=-97; /M: SY='E'; M= 5,-152, 44, 52,-147, -73,-140, -45, -5, -7, -2, -10, -32, -30, 15,-136, -25, 40,-161,-145; D=-38; /I: I=-38; DM=-97; /M: SY='I'; M= -43, -1,-155, -22, 24, -55,-149, 59,-145, 55,-118, -32,-156,-146, 18,-147, -25, -10,-150,-132; /M: SY='D'; M= -8,-150, 53, 27,-155, -53,-137,-146, -1,-151,-146, 52, -13,-130, 0, 11, 48, -1,-166,-148; /M: SY='Q'; M= -31,-157, 8, 16,-157, -48, 73, -42, 60,-151,-141, -36, 5, 73, -56,-132, 14,-151,-159,-140; /M: SY='E'; M= -13,-154, 64, 66,-157, 9, -9, -25,-131, -46,-147, -35,-143, 18,-138, 41,-133,-148,-162,-147; /M: SY='E'; M=-140,-156, 31, 94,-151,-153,-135,-144, -30, 5, 28, -18, -31, -2,-134,-137, -19, -26,-160,-147; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 51 in 51 different sequences |
| Number of true positive hits | 51 in 51 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | CNNM transmembrane |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
51 sequences
CNNM1_CAEEL (A3QM97), CNNM1_HUMAN (Q9NRU3), CNNM1_MOUSE (Q0GA42), CNNM2_CAEEL (Q9GYL2), CNNM2_HUMAN (Q9H8M5), CNNM2_MOUSE (Q3TWN3), CNNM2_RAT (Q5U2P1), CNNM3_CAEEL (A0A131MCZ8), CNNM3_HUMAN (Q8NE01), CNNM3_MOUSE (Q32NY4), CNNM4_CAEEL (Q17586), CNNM4_HUMAN (Q6P4Q7), CNNM4_MOUSE (Q69ZF7), CNNM4_RAT (P0C588), CNNM4_XENTR (A0JPA0), CNNM5_CAEEL (G5ED05), MAM3_YEAST (Q12296), PAEA_ECO57 (P0AE47), PAEA_ECOL6 (P0AE46), PAEA_ECOLI (P0AE45), PAEA_HAEIN (P44717), PAEA_SALT1 (A0A0F6BAS6), UEX_DROME (A0A0B7P9G0), Y107_HAEIN (Q57017), Y1254_SYNY3 (P74078), Y1327_ARATH (Q9ZVS8), Y146_MYCGE (Q49399), Y1559_ARATH (Q84R21), Y159_MYCPN (P75586), Y1733_ARATH (Q8RY60), Y1841_MYCTO (P9WLQ6), Y1841_MYCTU (P9WLQ7), Y1842_MYCTO (P9WFP2), Y1842_MYCTU (P9WFP3), Y2366_MYCTO (P9WFP0), Y2366_MYCTU (P9WFP1), Y2387_MYCBO (P67131), Y2452_ARATH (Q9ZQR4), Y260_SYNY3 (P74409), Y3307_ARATH (Q9LK65), Y4370_ARATH (Q8VZI2), Y4423_ARATH (Q4V3C7), Y4424_ARATH (Q67XQ0), Y5279_ARATH (Q9LTD8), YFJD_ECOLI (P37908), YHDP_BACSU (O07585), YHDT_BACSU (O07589), YJ23_SCHPO (Q9USJ3), YQHB_BACSU (P54505), YRKA_BACSU (P54428), YUGS_BACSU (O05241)» more
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