PROSITE entry PS51857
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General information about the entry
| Entry name [info] | CSD_2 |
| Accession [info] | PS51857 |
| Entry type [info] | MATRIX |
| Date [info] |
28-MAR-2018 CREATED;
26-FEB-2020 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00304 |
| Associated ProRule [info] | PRU01204 |
Name and characterization of the entry
| Description [info] | Cold-shock (CSD) domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=67; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=62; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.0764334; R2=0.0093635; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=8286.4355469; R2=2.9217715; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1221; H_SCORE=11854; N_SCORE=13.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=473; H_SCORE=9668; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-31; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='M'; M= -34, -79, -36, -13, -71, -48, 0, -61, 23, -29, 71, 19, 7, -3, 54, -45, -45, 5, -82, -65; /M: SY='M'; M= 4, -33, -66, 23, 2, -1, -62, -19, -38, 6, 54, -42, -13, -1, 7, -26, -12, -11, -70, 29; /M: SY='T'; M= -28, -18, -61, 4, -41, -72, -5, -25, 7, -11, -14, -7, -3, 47, 20, 0, 53, -33, -81, -43; /M: SY='G'; M= -34, -78, -67, -77, -84, 96, -73, -90, -72, -54, -76, -53, -71, -69, -79, -3, -68, -83, -77, -79; /M: SY='T'; M= -61, -73, -68, -20, 4, -77, 24, 19, 15, -36, 24, -48, -22, -17, -5, -10, 49, 32, -79, -22; /M: SY='V'; M= -59, 62, -83, -80, -58, -84, -84, 56, -77, -21, -46, -26, -81, -77, -80, -12, -56, 71, -87, -65; /I: I=-28; MD=-70; /M: SY='K'; M= -17, -24, -58, 14, -26, -72, -64, -76, 86, -77, -69, -24, -9, -48, -21, -26, 2, -29, -78, -69; D=-28; /I: I=-28; MD=-70; /M: SY='W'; M= 9, 12, -80, -43, -28, -38, -83, -9, -15, -72, -71, -28, -77, -32, -41, 5, 19, -71, 136, -50; D=-28; /I: I=-28; MD=-70; /M: SY='F'; M= -31, -76, -86, -80, 90, -84, -69, -49, -7, 4, 21, -79, -85, -79, -72, -74, -68, 8, 48, 33; D=-28; /I: I=-28; MD=-70; /M: SY='N'; M= -72, -12, 22, 1, -7, -68, -59, -86, -18, -88, -79, 85, -12, -6, -12, -4, -61, -86, -95, -76; D=-28; /I: I=-28; MD=-70; /M: SY='P'; M= 11, -29, -7, 6, -83, -10, -74, -42, -13, -43, -72, -6, 16, -25, 12, -3, -20, 11, -91, -79; D=-28; /I: I=-28; MI=-70; MD=-70; IM=-70; DM=-70; /M: SY='E'; M= -19, -79, 30, 42, -81, -7, -61, -79, 35, -41, -16, -16, -68, 8, 20, 4, 11, -74, -84, -72; D=-28; /I: I=-28; DM=-70; /M: SY='K'; M= -25, -77, 40, -3, -79, -44, -20, -77, 71, -75, 27, 15, -67, -4, 0, 15, -30, -73, -82, -67; D=-28; /I: I=-28; DM=-70; /M: SY='G'; M= -7, -77, -14, -32, -82, 83, -9, -84, -65, -81, 11, 20, -10, -25, -46, -20, -64, -79, -79, -75; D=-28; /I: I=-28; DM=-70; /M: SY='F'; M= -70, -74, -29, -71, 96, -78, 31, -52, 5, -48, -52, -21, -80, -71, -64, -67, -17, -7, -5, 67; /M: SY='G'; M= -50, -77, -8, -73, -83, 102, -70, -91, -69, -86, -76, -49, -68, -67, -76, -49, -68, -84, -75, -78; /M: SY='F'; M= -71, -72, -81, -18, 114, -80, -67, -8, -74, -25, -51, -73, -82, -26, -73, -11, -64, -53, -45, -24; /M: SY='I'; M= -63, -75, -85, -82, -49, -89, -84, 96, -76, 1, -36, -77, -75, -74, -36, -72, -57, 36, -75, -57; /M: SY='T'; M= -18, 25, -33, 25, -67, -67, -11, 2, 0, -64, -60, 5, -65, 28, 0, 21, 62, -18, -79, 3; /I: I=-18; MD=-45; /M: SY='P'; M= -59, 22, -35, -68, -77, -70, -72, -74, -58, -78, 28, -77, 85, 12, 5, -72, -21, -28, -81, 28; D=-18; /I: I=-18; MI=0; MD=-45; IM=0; DM=-45; /M: SY='D'; M= -4, -24, 62, 41, -78, -22, -8, -39, -40, -19, -69, 10, -56, -35, -66, -2, -16, -1, -91, -72; D=-18; /I: I=-18; DM=-45; /M: SY='D'; M= -38, -80, 72, 21, -47, 16, -61, -15, -25, -55, -22, 29, -34, -57, -3, -10, -15, -74, -90, -73; D=-18; /I: I=-18; DM=-45; /M: SY='G'; M= -43, -4, 27, -36, -36, 64, -15, -64, -59, -81, -73, 25, -16, -40, 25, -9, -4, -43, -83, -73; D=-18; /I: I=-18; DM=-45; /M: SY='G'; M= -19, -84, -1, -19, -89, 57, -72, -88, 4, -88, -79, -48, 24, -10, -8, 26, -65, -57, -86, -81; D=-18; /I: I=-18; DM=-45; /M: SY='K'; M= 8, -76, 18, 40, -77, -16, -62, -43, 45, -65, -66, 4, 0, -8, 4, -5, -35, 12, -82, -70; D=-18; /I: I=-18; DM=-45; /M: SY='D'; M= -66, -80, 92, 36, -85, -67, -56, -81, -5, -82, -78, 35, -68, -51, -5, -9, -58, -31, -96, -72; D=-18; /I: I=-18; DM=-45; /M: SY='V'; M= -28, -7, -84, -78, -8, -84, -76, 29, -74, 36, -7, -79, -81, -74, -22, -71, -58, 68, 4, 4; D=-18; /I: I=-18; DM=-45; /M: SY='F'; M= -75, -76, -82, -77, 107, -82, -62, -54, -73, -47, -53, -75, -6, -5, -33, -71, -29, -59, -43, 57; D=-18; /I: I=-18; MI=0; MD=-45; IM=0; DM=-45; /M: SY='F'; M= -4, -11, -84, -78, 82, -80, -75, -33, -76, 8, -45, -77, -81, -79, -75, -67, -58, 68, -62, -40; /M: SY='H'; M= -65, -79, -55, -54, -69, 1, 138, -84, -26, -70, -56, -44, -69, -12, -26, -10, -18, -82, -94, -21; /I: I=-20; MD=-51; /M: SY='F'; M= -16, -14, -10, -20, 64, -77, -46, 25, -38, -25, -51, -67, -77, 52, -15, -64, -62, 11, 8, 51; D=-20; /I: I=-20; MD=-51; /M: SY='S'; M= -33, -68, -15, -56, -73, -30, -62, -26, 26, -72, -66, -40, -65, -27, -3, 82, 33, -19, -82, -66; D=-20; /I: I=-20; MD=-51; /M: SY='A'; M= 52, -71, 45, 28, -80, -16, -61, -73, 13, -75, -68, 0, -9, 9, -57, 17, -30, -41, -82, -71; D=-20; /I: I=-20; MD=-51; /M: SY='I'; M= -28, -26, -80, -24, 21, -55, -76, 71, -74, 18, 28, -74, -76, -72, -76, -69, -10, 36, -72, -19; D=-20; /I: I=-20; MD=-51; /M: SY='Q'; M= 9, -76, 7, 30, -55, -65, 4, -71, 21, -49, -64, 27, -10, 64, -19, 9, -9, -22, -79, -12; D=-20; /I: I=-20; MD=-51; /M: SY='M'; M= -17, -73, 23, -37, -74, 45, -63, -67, -36, -50, 56, 23, -37, -19, -31, 36, 0, -15, -83, -69; D=-20; /I: I=-20; MD=-51; /M: SY='D'; M= -16, -78, 48, 45, -72, 13, -23, -53, 11, -80, -73, 43, -8, -11, -8, -2, -18, -76, -86, -72; D=-20; /I: I=-20; MD=-51; /M: SY='G'; M= -53,-101, 3, -44,-107, 66, -90,-113, -89,-110,-100, -3, -93, -87, -97, -53, -88,-107,-103,-101; D=-20; /I: I=-20; MI=0; MD=-51; IM=0; DM=-51; /M: SY='F'; M= -39, -81, -88, -86, 81, -88, -71, -6, -81, 18, -35, -15, -91, -83, -47, -42, -47, -32, -58, 42; D=-20; /I: I=-20; DM=-51; /M: SY='R'; M= -55, -78, 24, 22, -77, -49, -16, -68, 41, -72, -66, 13, -70, -18, 63, -11, -12, 14, -83, -67; D=-20; /I: I=-20; DM=-51; /M: SY='S'; M= -39, 22, 17, 1, -76, -56, 1, -70, -60, -27, -67, -28, 13, 10, -66, 59, 54, -46, -88, -70; D=-20; /I: I=-20; DM=-51; /M: SY='L'; M= -65, -70, -84, -76, 2, -85, -70, 7, -77, 80, -7, -82, -10, -72, -75, -75, -61, 16, -71, -53; /I: I=-45; MD=-115; /M: SY='K'; M= -16, -78, 10, 28, -65, -15, -12, -34, 52, -15, -63, -13, -67, 51, 16, -38, 4, -58, -79, -66; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='E'; M= 4, -75, 3, 76, -73, -71, -60, 5, 8, -28, -61, -57, 5, 3, -55, -12, 4, -2, -80, -68; /M: SY='G'; M= -33, -76, -3, -49, -83, 97, -67, -89, -66, -85, -75, 10, -68, -40, -60, -49, -66, -83, -76, -77; /M: SY='Q'; M= -25, -79, 75, 45, -81, -67, -53, -52, -21, -27, -21, -5, -65, 78, -53, -53, -14, -72, -84, -66; /M: SY='R'; M= 2, -11, -7, 42, -75, -45, 19, -24, 39, -71, -17, -37, 12, -21, 45, 9, -6, -49, 3, -54; /M: SY='V'; M= -53, -67, -83, -77, -53, -85, -85, 22, -75, -26, -41, -78, -79, -77, -77, -67, -51, 99, -86, -61; /M: SY='E'; M= -8, -74, -44, 76, -78, -66, -56, -40, -1, -73, -67, 12, -16, 25, -6, 28, 31, -67, -80, -69; /M: SY='F'; M= -52, -73, -84, -81, 112, -54, -62, -50, -76, -43, -51, -75, -33, -82, -73, -71, -66, -28, -40, 59; /M: SY='D'; M= -51, 15, 51, 42, -72, -61, -59, -4, -8, -67, -64, 0, -65, 9, 4, 11, 45, -5, -83, -21; /M: SY='I'; M= -34, -31, -80, -39, 20, -51, -76, 60, -71, 11, 17, -75, -1, -71, -16, -68, -39, 55, 10, -44; /M: SY='E'; M= -39, 48, -11, 51, -71, -22, -30, -7, 11, -53, -61, -56, -66, 4, -16, 30, 20, 27, -82, -67; /I: I=-14; MD=-34; /M: SY='E'; M= -40, -75, 14, 37, -12, -40, -14, -56, 4, -33, -35, 26, 8, 34, 2, 12, 18, -9, -78, -8; D=-14; /I: I=-14; MD=-34; /M: SY='G'; M= -57, -76, 35, -27, -76, 64, -63, 1, -13, -31, -67, 41, -70, -60, -18, 10, -21, -44, -82, -72; D=-14; /I: I=-14; MD=-34; /M: SY='Q'; M= -53,-106, -85, -36,-107, -25, -83,-101, -11,-100, -22, -49, 26, 49, 14, -11, -39,-100,-103, -94; D=-14; /I: I=-14; MI=0; MD=-34; IM=0; DM=-34; /M: SY='N'; M= -24, -80, 21, 8, -83, -4, -17, -80, 14, -30, -72, 48, -4, 16, -7, -16, 20, -77, -90, -75; D=-14; /I: I=-14; DM=-34; /M: SY='K'; M= -16, -79, -22, -4, -82, 44, 3, -84, 63, -73, -49, -1, -69, -4, 35, -32, -63, -79, -79, -70; D=-14; /I: I=-14; DM=-34; /M: SY='G'; M= -25, -78, -26, -60, -78, 62, -64, -50, 39, -32, -34, 11, -71, 28, -1, -9, -26, -75, -77, -28; D=-14; /I: I=-14; DM=-34; /M: SY='P'; M= 1, 3, -37, 15, -39, -72, -31, -31, -7, 6, -30, -24, 72, 15, -65, -20, 9, -14, -80, -48; D=-14; /I: I=-14; MI=0; MD=-34; IM=0; DM=-34; /M: SY='Q'; M= -11, 13, -52, 10, -72, -47, 21, 4, 10, -65, 13, -57, -70, 57, 21, 35, -23, -3, -80, -27; /M: SY='A'; M= 88, -66, -69, -26, -74, -23, -23, -32, -65, -42, -62, -64, -69, -39, -69, -26, -29, -55, -77, -22; /M: SY='V'; M= 25, 4, -37, -26, -33, -33, -69, 1, -11, -18, -56, -63, -73, -19, -6, 7, 33, 35, -77, 15; /M: SY='N'; M= -27, 5, -9, 11, -80, -46, -4, -56, 10, -79, -69, 87, -72, 20, 16, 2, -26, -43, -89, -71; /M: SY='V'; M= -47, -72, -84, -79, -56, -85, -85, 43, -46, -6, -45, -78, -80, -77, -78, -12, -55, 83, -86, -64; /M: SY='T'; M= -13, -11, -65, -2, -63, -42, -55, -7, 11, -64, 21, -28, -44, 9, 29, 13, 36, 10, 25, 1; /M: SY='L'; M= -10, -18, -3, -34, -64, -22, -23, 8, 24, 29, -52, -68, 14, -64, 3, -31, -48, 26, -82, -67; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 213 in 185 different sequences |
| Number of true positive hits | 213 in 185 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 9 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | CSD |
| Version [info] | 3 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
185 sequences
CAPA_PSEFR (P72188), CAPB_PSEFR (P0A106), CAPB_PSESM (P0A105), CHSP1_HUMAN (Q9Y2V2), CHSP1_MOUSE (Q9CR86), CHSP1_RAT (Q9WU49), CS72_SALH5 (P0DV90), CSDC2_HUMAN (Q9Y534), CSDC2_MOUSE (Q91YQ3), CSDC2_RAT (Q63430), CSDE1_CAVPO (P29174), CSDE1_HUMAN (O75534), CSDE1_MOUSE (Q91W50), CSDE1_RAT (P18395), CSP1_ARATH (O65639), CSP1_LACPL (P71478), CSP2_ARATH (Q41188), CSP2_LACPL (P96349), CSP3_ARATH (Q94C69), CSP4_ARATH (Q38896), CSP7_STRCL (Q01761), CSPA_AERHY (Q44078), CSPA_AERSA (Q44317), CSPA_BACAN (Q81TW8), CSPA_BACCE (Q45096), CSPA_BACCR (Q81GQ6), CSPA_BORBR (P0A353), CSPA_BORPA (P0A354), CSPA_BORPE (P0A352), CSPA_CITFR (Q46051), CSPA_ECO57 (P0A9Y1), CSPA_ECOL6 (P0A9Y0), CSPA_ECOLI (P0A9X9), CSPA_KLEAK (Q46664), CSPA_KLEPN (Q48493), CSPA_LISIN (P0A356), CSPA_LISMO (P0A355), CSPA_MICLC (O30875), CSPA_MYCBO (P63849), CSPA_MYCS2 (A0R5E1), CSPA_MYCTO (P9WP74), CSPA_MYCTU (P9WP75), CSPA_PHOLD (Q51929), CSPA_PHOPO (Q52287), CSPA_PSEAE (P95459), CSPA_RHIME (Q9Z3S6), CSPA_RICBR (Q1RHK6), CSPA_RICCN (Q92GV1), CSPA_RICFE (Q4UMU5), CSPA_RICPR (Q9ZCP9), CSPA_RICTY (Q68W69), CSPA_SALEN (P0A9Y5), CSPA_SALTI (P0A9Y3), CSPA_SALTY (P0A9Y2), CSPA_SALVI (Q56178), CSPA_SHEVD (Q9S1B7), CSPA_SHIBO (Q53816), CSPA_SHIFL (P0A9Y4), CSPA_STAA3 (Q2FH36), CSPA_STAA8 (Q2FYN2), CSPA_STAAB (Q2YY16), CSPA_STAAC (Q5HG18), CSPA_STAAM (Q7A2R8), CSPA_STAAN (Q7A5P3), CSPA_STAAR (Q6GH06), CSPA_STAAS (Q6G9F9), CSPA_STAAW (Q7A0X3), CSPA_STAEQ (Q5HPE0), CSPA_STAES (Q8CP90), CSPA_STAHJ (Q4L6A7), CSPA_STAS1 (Q49XK3), CSPA_STIAD (P72366), CSPA_STRDY (Q53984), CSPA_STRP1 (P0C0F1), CSPA_STRP3 (P0DA48), CSPA_STRP6 (Q5X9L4), CSPA_STRP8 (P0A361), CSPA_STRPQ (P0DA49), CSPA_STRPY (P0C0F0), CSPA_VIBCH (Q9KN00), CSPA_YEREN (Q56922), CSPB_BACCE (Q45097), CSPB_BACCL (P41016), CSPB_BACSU (P32081), CSPB_ECOLI (P36995), CSPB_GEOSE (P42016), CSPB_LISIN (P0A358), CSPB_LISMO (P0A357), CSPB_SPOGL (P41018), CSPB_YEREN (P0A363), CSPB_YERPE (P0A362), CSPC_BACAN (P62169), CSPC_BACCE (P62170), CSPC_BACCR (P62171), CSPC_BACSU (P39158), CSPC_BUCAI (P57407), CSPC_ECO57 (P0A9Y8), CSPC_ECOL6 (P0A9Y7), CSPC_ECOLI (P0A9Y6), CSPC_ECOLW (E0J500), CSPC_SALTI (P0A9Z0), CSPC_SALTY (P0A9Y9), CSPC_SHIFL (Q83RI9), CSPD_BACAN (Q81K90), CSPD_BACCE (Q45099), CSPD_BACCR (Q816H3), CSPD_BACSU (P51777), CSPD_ECO57 (P0A970), CSPD_ECOL6 (P0A969), CSPD_ECOLI (P0A968), CSPD_HAEIN (P46449), CSPD_SHIFL (P0A971), CSPD_VIBCH (Q9KSW4), CSPE_BACAN (Q81QK2), CSPE_BACCE (Q45100), CSPE_BACCR (Q81DK5), CSPE_BUCAI (P63237), CSPE_BUCAP (P63238), CSPE_BUCBP (Q89A90), CSPE_ECO57 (P0A974), CSPE_ECOL6 (P0A973), CSPE_ECOLI (P0A972), CSPE_ECOLW (E0J1Q3), CSPE_SHIFL (P0A975), CSPF_ECOL6 (P0A977), CSPF_ECOLI (P0A976), CSPF_STRCO (P48859), CSPG_ECO57 (P0A980), CSPG_ECOL6 (P0A979), CSPG_ECOLI (P0A978), CSPG_SHEVD (Q9S170), CSPG_SHIFL (P0A981), CSPH_ECO57 (P0A984), CSPH_ECOL6 (P0A983), CSPH_ECOLI (P0A982), CSPH_SALTI (P0A1E0), CSPH_SALTY (P0A1D9), CSPH_SHIFL (P0A985), CSPI_ECOL6 (P0A987), CSPI_ECOLI (P0A986), CSPJ_SALTI (P58726), CSPJ_SALTS (E1WGN1), CSPJ_SALTY (P0CL01), CSPS_STRTR (P81622), CSPV_VIBCH (Q9KL16), CSP_AQUAE (O67327), CSP_ARTGO (P54584), CSP_THEMA (O54310), GRP2_NICSY (P27484), LIN28_CAEBR (Q61CX7), LIN28_CAEEL (P92186), LIN28_CAERE (P91599), LIN28_DROME (Q9VRN5), LN28A_CHICK (Q45KJ5), LN28A_DANRE (Q803L0), LN28A_HUMAN (Q9H9Z2), LN28A_MOUSE (Q8K3Y3), LN28A_XENLA (Q8JHC4), LN28A_XENTR (Q5EB47), LN28B_CHICK (Q45KJ4), LN28B_HUMAN (Q6ZN17), LN28B_MOUSE (Q45KJ6), LN28B_XENLA (Q8AVK2), TAPA_PSEFR (P72191), TAPB_PSEFR (P72192), UNR_DROME (B7Z0E2), Y4CH_SINFN (P55390), Y9705_DROME (Q9VVA0), YB3_XENLA (Q00436), YBOX1_BOVIN (P67808), YBOX1_CHICK (Q06066), YBOX1_DANRE (B5DE31), YBOX1_HUMAN (P67809), YBOX1_MOUSE (P62960), YBOX1_RABIT (Q28618), YBOX1_RAT (P62961), YBOX1_XENLA (P21573), YBOX2_HUMAN (Q9Y2T7), YBOX2_MOUSE (Q9Z2C8), YBOX3_HUMAN (P16989), YBOX3_MOUSE (Q9JKB3), YBOX3_RAT (Q62764), YBOXH_APLCA (P41824), YBX2A_XENLA (P21574), YBX2B_XENLA (P45441)» more
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| PDB [Detailed view] |
64 PDB
1C9O; 1CSP; 1CSQ; 1G6P; 1H95; 1HZ9; 1HZA; 1HZB; 1HZC; 1I5F; 1MJC; 1NMF; 1NMG; 1WFQ; 1X65; 2BH8; 2ES2; 2F52; 2HAX; 2I5L; 2I5M; 2L15; 2LXJ; 2LXK; 2YTV; 2YTX; 2YTY; 3AQQ; 3MEF; 3PF4; 3PF5; 3TRZ; 3TS0; 3TS2; 4A4I; 4QQB; 5JX4; 5UDZ; 5YTS; 5YTT; 5YTV; 5YTX; 6A6J; 6A6L; 6KTC; 6KUG; 6LMR; 6LMS; 6SZZ; 6T00; 6Y4H; 6Y6E; 6Y6M; 6Y96; 7F3I; 7F3J; 7F3K; 7F3L; 7ZHH; 7ZHR; 8H1I; 8OPS; 8OPT; 8OST » more |