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PROSITE entry PS51905


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General information about the entry

Entry name [info] ZF_UBZ1
Accession [info] PS51905
Entry type [info] MATRIX
Date [info] 13-NOV-2019 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51905
Associated ProRule [info] PRU01253

Name and characterization of the entry

Description [info] Zinc finger UBZ1-type profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=27;
/DISJOINT: DEFINITION=PROTECT; N1=3; N2=25;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2411482; R2=0.0073204; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2682.5251465; R2=0.6256983; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1197; H_SCORE=3431; N_SCORE=11.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=582; H_SCORE=3047; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-22; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='W';  M=-42, 43,-42, 14,-37,-48, 43,  4,-36,-44,-40, -9, 38, 34,-40,-20,-42,-46,120,-25;
/M: SY='K';  M=-40,-52,-39,-26,  4,-50,-34,-40, 73,  5, 35,-31,-45,-21, 48,-37,-36,-40,-46,-33;
/M: SY='V';  M=-31,-47,-29, 30,-45,-45,-36,-10, 19,-37,-33, 29,-43, 37,-13, 10, 18, 39,-58,-41;
/M: SY='C';  M=-37,146,-57,-57,-47,-52,-57,-54,-53,-45,-45,-43,-68,-60,-59,-40,-37,-42,-77,-58;
/M: SY='P';  M=-41,-66,-36, 25,-61,-45,-43,-51,-35,-59,-47,-46,114,-36,-47,-38,-35,-54,-55,-58;
/M: SY='M';  M=-40,-48,-52,  6, 35,-59,-43, 48,-47, 36, 69,-50,-51,-42,-48,-48,-37,  5,-44,-24;
/M: SY='C';  M=-37,146,-57,-57,-47,-52,-57,-54,-53,-45,-45,-43,-68,-60,-59,-40,-37,-42,-77,-58;
/M: SY='Q';  M=-31,-53, 27, 28,-59, 30,-32,-56, 29,-54,-45, -9, -4, 58,-25, 24,-32,-53,-54,-44;
/M: SY='E';  M= -2,-49,-25, 61,-44,-47,-36,-35, 38, 15,-32,-34,-40,-21,-25,  8,-32,  5,-53,-42;
/M: SY='Q';  M=-35,-53,-38, 12,-43,  3,-35, 23,-25, -7, 34,-35,-45, 64, 33,-12,-14,  1,-51,-37;
/M: SY='F';  M=-51,-48,-62,-58,108,-58,-39,-25,-53,-17,-26,-52,-62,-62,-50,-49,-43,-30,-15, 43;
/M: SY='P';  M=-38,-63,-37, 12,-60,-42,-43,-50,-36,-59,-46,-44,111,-36,-47, 11,-32,-53,-55,-56;
/I:         I=-24; MD=-61;
/M: SY='P';  M= 27,-53,-49,-41,-50,-44,-50,-33,-45, -8,-37,-48, 79,-44,-51, 11,-33, 19,-59,-51; D=-24;
/I:         I=-24; MD=-61;
/M: SY='H';  M=-37,-54, 38, 15,-58,  5, 51,-58,-14,-56,-47, 31,-45, 30,-35, 22, 12,-54,-67,-43; D=-24;
/I:         I=-24; MD=-61;
/M: SY='Y';  M=-50, 47,-63,-63, -1,-65,-46, 19,-58,-38,-39,-57,-68,-56,-59,  3,-46,  7,-40, 70; D=-24;
/I:         I=-24; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='D';  M=-33,-50, 66, 31,-57,-37,-31,-54,-28,-55,-49, 24, 24, 11,-36, 40,  7,-50,-64,-46;
/M: SY='Q';  M=-40,-56, 17,-19, 42,-47,-29,-47, 39,-42,-36,-28,-46, 80, 32,-32,-38,-48,-42,-26;
/M: SY='Q';  M=-32,-52, 42,-20,-58, 26,-30,-38,-26,-51,-42, 28,-42, 76,-30, 18, 11,-49,-57,-43;
/M: SY='A';  M= 38,-46, 29,-32,-41,-30, 27, 21, 13, -3,-29,-33,-46, -2,-36,-10,-31, 20,-56,-38;
/M: SY='F';  M=-48,-46,-59,-56, 98,-58,-41,-22,-52, 24,-22,-51,-59,-57,-50,-46,  1,-27,-21, 25;
/M: SY='E';  M=-38,-55,-21, 75,-40,-54,-31,  6,-22,  8,-32,-37,-40, 29, 20,-36,-37,-36,-47, 15;
/M: SY='D';  M=-19,-54, 56, 41,-56,-20,-31,-57, 33,-53,-46,-24,-41,-20, 51,-31,  4,-50,-58,-44;
/M: SY='H';  M=-45,-57,-29,-29,-43,-47,138,-62,-34,-44,-29,-18,-46,-23,-28,-35,-44,-61,-79,-12;
/M: SY='V';  M=-32,-44,-57,-52,-27,-59,-54, 39,-49, 18, 41,-51,-52,-49,-51,-42,  6, 69,-57,-34;
/M: SY='H';  M=-41,-53, 43, 50, 46,-45, 50,-47,-28,-25,-39, 35,-44, 24,-33,-33,-36,-47,-49,-26;
/M: SY='C';  M=-26, 78,-39,-41,-45,  8,-41,-41,-38,-40, 38,-27,-43,-36,-44, 53, 54,-35,-61,-43;
/M: SY='H';  M=-45,-57,-29,-29,-43,-47,138,-62,-34,-44,-29,-18,-46,-23,-28,-35,-44,-61,-79,-12;
/I:         E1=0; IE=-255; DE=-255;
» more

Post-processing [info]

COMPETES_HIT_WITH PS50157; PS51801; PS51906; PS51907; PS51908

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 32 in 24 different sequences
Number of true positive hits 32 in 24 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] ZN_FING
Feature description [info] UBZ1-type
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
24 sequences

CACO1_BOVIN (Q2KJ21), CACO1_HUMAN (Q9P1Z2), CACO1_MOUSE (Q8CGU1), 
CACO1_PONAB (Q5RD60), CACO1_RAT   (Q66HR5), CACO2_BOVIN (O18737), 
CACO2_HUMAN (Q13137), CACO2_MACFA (Q4R914), CACO2_PONAB (Q5R7H1), 
CACO2_XENTR (Q6DF48), SPNF_DROME  (Q9V9Y9), TANK_HUMAN  (Q92844), 
TANK_MOUSE  (P70347), TAXB1_BOVIN (Q2KJE0), TAXB1_HUMAN (Q86VP1), 
TAXB1_MOUSE (Q3UKC1), TAXB1_PONAB (Q5R4U3), TAXB1_RAT   (Q66HA4), 
TAXB1_XENTR (Q6P3P1), TBKB1_HUMAN (A7MCY6), TBKB1_MOUSE (A2A9T0), 
TBKB1_RAT   (Q6DG50), TXB1A_DANRE (Q1LWB0), TXB1B_DANRE (Q6P132)
» more

PDB
[Detailed view]
9 PDB

2M7Q; 2MXP; 4BMJ; 4XKL; 4Z4K; 4Z4M; 5AAQ; 5AAS; 5YT6