PROSITE entry PS51912
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General information about the entry
| Entry name [info] | DMAP1_BIND |
| Accession [info] | PS51912 |
| Entry type [info] | MATRIX |
| Date [info] |
22-APR-2020 CREATED;
07-APR-2021 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51912 |
| Associated ProRule [info] | PRU01260 |
Name and characterization of the entry
| Description [info] | DMAP1-binding domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=103; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=98; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3147242; R2=0.0054570; TEXT='-LogE'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=15076.8457031; R2=6.7161689; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1409; H_SCORE=24540; N_SCORE=10.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=767; H_SCORE=20228; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-24; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='N'; M= -31, -19, 50, 13, -70, -66, -26, -11, -57, -37, -60, 61, 26, -11, -64, -33, 13, 37, -89, -68; /M: SY='Y'; M= -14, -22, -12, -28, -48, -73, -62, 31, -49, 5, 13, -67, 38, -19, -68, 7, -11, 15, 42, 65; /M: SY='P'; M= -7, -4, -26, -26, -36, -49, -16, -48, -60, -6, -62, -7, 71, -57, -39, 66, 1, -25, -80, -67; /M: SY='T'; M= -2, -36, -15, -16, -24, -12, -13, -56, 12, 16, -55, -4, 16, -57, -5, 25, 46, 1, -79, -63; /M: SY='L'; M= -40, -22, -82, -47, -43, -84, -69, 0, -76, 86, -30, -43, -83, -70, -75, -75, -62, -9, -72, -55; /M: SY='P'; M= -63, -86, -63, -55, -83, -65, -67, -73, -60, -82, -70, 0, 118, -63, -24, 12, -12, -76, -80, -80; /M: SY='E'; M= 3, -76, 43, 68, -40, -51, -23, -68, 10, 0, -63, -13, 18, -30, -34, -15, -35, -30, -80, -36; /M: SY='D'; M= -8, -9, 84, 57, -80, -14, -22, -52, -14, -77, -73, -1, -64, -49, -32, -53, 3, -54, -88, -39; /M: SY='V'; M= -8, -68, -81, -76, -51, -50, -79, 37, -74, 34, -39, -76, -78, -73, -76, -45, -24, 76, -80, -60; /M: SY='Q'; M= -62, -27, -60, -45, -77, -56, -52, -73, 19, -21, -59, -54, -71, 89, 82, -30, -38, -52, -74, -62; /M: SY='E'; M= 1, -24, -4, 53, -69, -31, -20, 0, 13, 10, -25, -3, -67, 15, 22, 8, -38, -30, -78, -65; /M: SY='K'; M= 8, -76, -55, 27, -77, -53, -25, -17, 62, -72, -63, -53, -30, 34, 54, 12, -57, -68, -75, -65; /M: SY='W'; M= -41, -74, -86, -76, -25, -82, -73, -15, -48, 77, -36, -83, -41, -70, -40, -76, -66, -19, 104, -48; /M: SY='Q'; M= 48, -72, 47, -46, -76, -38, -21, -71, 6, -41, -63, 15, -68, 62, 5, 5, -55, -46, -12, -20; /M: SY='E'; M= -13, -9, 16, 77, -39, -69, 6, -39, 9, -73, -67, 33, -63, 45, 0, -54, -40, -44, -81, -67; /M: SY='L'; M= -8, -69, -42, -72, -45, -81, -17, -34, -49, 82, -33, -77, -81, -68, -34, -71, -34, 9, -73, -55; /M: SY='E'; M= -27, -79, 73, 79, -79, -70, -56, -8, -17, -52, -70, -2, -62, -23, -56, -56, -37, -70, 20, -69; /M: SY='Q'; M= -62, -75, -18, 25, -59, -28, -58, -16, -39, 56, -45, 5, -72, 69, 0, -22, -60, -55, -75, -60; /M: SY='E'; M= 6, -78, 44, 76, -79, -42, -55, -78, 31, -39, -68, -30, -35, 31, -13, -54, -59, -73, -79, -32; /I: I=-29; MD=-75; /M: SY='L'; M= -71, -75, -85, -79, -8, -88, -69, -31, -77, 76, -38, -83, -44, -73, -20, -41, -28, -31, -70, 24; D=-29; /I: I=-29; MI=0; MD=-75; IM=0; DM=-75; /M: SY='Y'; M= -5, -76, -63, 19, -36, -69, -60, -29, 4, -27, -25, -13, -74, -32, -17, 54, -25, -21, -69, 56; D=-29; /I: I=-29; DM=-75; /M: SY='E'; M= -65, -81, 65, 70, -33, -43, -27, -35, -52, -37, -72, 29, -66, -4, -28, -21, -35, -52, -88, -70; D=-29; /I: I=-29; DM=-75; /M: SY='G'; M= -55, -10, 31, 37, -84, 84, -67, -90, -63, -85, -77, -51, -68, -22, -71, -53, -67, -84, -3, -76; D=-29; /I: I=-29; DM=-75; /M: SY='D'; M= -64, 5, 97, -3, -73, -12, -57, -71, -59, 15, -67, -9, -70, -21, -65, 3, -57, -71, -90, -26; D=-29; /I: I=-29; DM=-75; /M: SY='I'; M= -64, -76, -85, -82, -48, -88, -81, 97, -78, 29, -5, -76, -75, -73, -80, -36, -59, -14, -73, -56; /M: SY='T'; M= -30, -61, -57, -60, -68, -67, -68, -59, -57, -64, -60, -47, -59, -61, -66, -6, 113, -51, -88, -66; /M: SY='Q'; M= -40, -81, -24, 61, -78, -71, -23, -34, -9, -10, -29, -55, -11, 98, -19, -35, -60, -43, -76, -64; /M: SY='K'; M= -62, -78, -54, -6, -81, -70, -56, -79, 101, -77, -65, -48, -63, 55, -27, -55, -58, -75, -72, -65; /M: SY='G'; M= -50, -77, -59, 18, -83, 99, -69, -90, -66, -85, -75, -51, -67, -62, -74, -50, -67, -83, -74, -77; /M: SY='Y'; M= -71, 24, -71, -73, 44, -78, 38, -58, -67, -53, -51, -69, -82, -63, -64, -66, -30, -62, -34, 122; /M: SY='N'; M= -40, -75, 29, 64, -73, -44, -54, -1, 7, -31, -19, 70, -66, -23, -55, -55, -55, -3, -6, -68; /M: SY='K'; M= -63, -75, -58, -46, -48, -71, -58, -67, 95, 16, -57, -5, -67, 4, 1, -34, -39, -67, -73, -63; /M: SY='K'; M= -58, -75, -54, 16, -75, -67, -57, -45, 83, -25, -15, -50, -64, 25, 11, 33, -12, -68, -75, -65; /M: SY='K'; M= -65, -78, -62, -49, -68, -75, -57, -67, 78, 21, -56, -56, -70, -44, 75, -61, -61, -66, -73, -62; /M: SY='A'; M= 42, -5, -28, -57, -66, -51, -61, -40, 14, 21, -55, -1, -70, 12, 35, 23, 13, -57, -76, -38; /M: SY='K'; M= 38, -73, -13, 10, -44, -43, -25, -50, 50, -9, -24, -13, -68, 3, 46, -7, -57, -64, 7, -63; /M: SY='L'; M= -67, -71, -85, -78, -42, -87, -71, 49, -78, 81, -6, -82, -82, -71, -76, -76, -62, -34, -72, -54; /M: SY='L'; M= -67, -70, -84, -78, 51, -85, -70, 20, -78, 75, -33, -80, -83, -74, -76, -74, -29, -3, -65, -45; /M: SY='E'; M= 33, -75, 4, 55, -28, 3, 7, -76, -5, -50, -65, -54, -65, 32, 46, -14, -40, -69, -77, -65; /M: SY='P'; M= -5, -81, 28, 36, -83, -12, -62, -77, 6, -80, -71, -57, 89, -29, -6, 10, -37, -75, -80, -75; /M: SY='Y'; M= 28, -8, -74, -73, 81, -72, 11, -39, -69, -51, -53, -33, -80, -69, -68, -42, -63, -57, -42, 92; /M: SY='L'; M= -20, -73, -71, -26, -15, 36, -9, 26, -15, 48, 2, -65, -74, 32, -66, -31, -61, -10, -73, -58; /M: SY='P'; M= -43, -76, -64, -9, 24, -12, 7, -31, -2, -6, 31, -25, 56, 29, -18, -3, -1, -20, -65, 38; /M: SY='Q'; M= 29, -71, -24, -26, -28, -24, -8, -25, 23, 27, -17, 22, -26, 33, -43, -2, -13, -19, -73, -1; /M: SY='Q'; M= 3, -28, 31, 13, -41, -67, 2, -7, 26, -20, -15, -38, 27, 52, -15, 3, 15, -48, -79, -64; /I: I=-7; MD=-19; /M: SY='Q'; M= -5, -85, -23, -33, -86, -57, -25, -77, -25, -19, -72, 8, 28, 44, -50, -11, 40, -48, -94, -79; D=-7; /I: I=-7; MD=-19; /M: SY='Q'; M= -12, -33, 3, -35, -51, 3, -17, -81, -25, -60, -14, 6, -6, 26, -41, -36, -1, -9, -98, -83; D=-7; /I: I=-7; MD=-19; /M: SY='E'; M= -36, -99, -8, 9, -98, -28, -26, -22, 8, -91, -86, -43, -91, 5, -50, -12, -9, -12,-106, -91; D=-7; /I: I=-7; MI=0; MD=-19; IM=0; DM=-19; /M: SY='K'; M= -30, -98, -80, -25,-101, -34, -84, -98, 19,-100, -92, 7, 8, -14, -28, 8, 1, -64,-104, -43; D=-7; /I: I=-7; DM=-19; /M: SY='E'; M= -25, -96, -1, 19,-100, -59, -10, -92, -28, -96, -89, 5, 14, -21, -34, 10, -14, -29,-106, -91; D=-7; /I: I=-7; DM=-19; /M: SY='P'; M= 12, -89, -27, -23, -92, -24, -32, -40, -5, -52, -80, -15, 21, -8, -7, 7, 11, -80, -97, -85; D=-7; /I: I=-7; DM=-19; /M: SY='A'; M= 27, -71, 1, 23, -71, -65, -15, -14, -12, -63, -3, -9, 3, 22, 12, 21, 18, 25, -81, -66; /M: SY='Q'; M= -13, -76, -5, -16, -35, -8, 33, -32, 37, -70, -62, -5, 17, 58, 13, 9, -8, -20, 8, 0; /M: SY='R'; M= -32, -74, 14, -12, -67, -34, -14, -24, 27, -14, -59, 21, -11, 32, 35, 13, 18, -4, -12, 0; /M: SY='Q'; M= -16, -40, -1, 39, -39, -69, 28, -50, 8, -48, -1, 8, -3, 59, 37, -15, -26, -27, -73, 18; /M: SY='H'; M= -24, -73, -29, -1, -64, -22, 38, -3, 6, 21, -9, 22, -20, 32, 22, -8, 4, 1, -78, -36; /M: SY='K'; M= -10, -16, -58, 7, -72, 8, -4, -13, 34, -19, -60, 9, 17, 29, 22, 19, 0, -20, -78, -66; /M: SY='S'; M= 3, -73, 36, -11, -75, -7, 3, -14, -19, -46, -64, 8, 4, 19, 31, 39, 23, -51, -82, -66; /M: SY='R'; M= -24, -74, -18, -42, -26, -32, 1, -22, 13, 24, -53, 6, 20, -55, 53, 5, 4, -1, 7, -60; /M: SY='E'; M= -18, -75, 34, 43, -74, 8, -26, -27, -12, -30, -8, 12, 13, 22, 0, 6, 9, -18, -9, -67; /M: SY='T'; M= 11, -71, -13, 20, -72, -14, 32, -33, 8, -16, -60, 5, 4, 20, -15, 19, 47, -32, -81, -64; /M: SY='E'; M= -12, -75, 29, 32, -77, 15, -13, -31, 31, -47, -65, 25, -66, 21, 27, 7, -11, -34, -80, -67; /M: SY='L'; M= -27, -71, 2, -30, 25, -29, 9, -52, -24, 30, -4, -36, -15, -31, 27, 28, 19, 7, -74, -55; /M: SY='R'; M= -10, -77, -1, 30, 7, -53, 51, -35, 32, -29, -28, -6, -22, 21, 53, -34, -31, -32, -76, -57; /M: SY='D'; M= -11, 36, 45, 17, -73, -48, 20, -72, 31, -39, -66, 17, -30, -51, -11, 37, 13, -33, -4, -37; /M: SY='E'; M= -59, -76, 28, 51, -32, -14, 26, -41, -12, 6, -36, -24, -41, 6, 27, 27, -12, -66, -77, -2; /M: SY='E'; M= -46, -77, 13, 63, -45, -55, -3, -17, 17, -41, -64, -20, -65, -8, 51, 20, -37, -30, -76, -6; /M: SY='H'; M= -22, -75, -59, 24, -3, -71, 54, 15, -6, 17, -51, 24, -22, 14, -27, -4, -17, -35, 20, 39; /M: SY='C'; M= -19, 52, -5, -8, -67, -66, 25, -25, -25, -18, 4, 19, -3, -8, 37, 34, 15, -11, -80, -6; /M: SY='E'; M= -13, -11, -32, 46, -74, -38, 8, -73, 5, -40, -16, 26, 8, 6, 24, 46, 8, -69, -80, -40; /M: SY='D'; M= -21, -78, 56, 45, -76, -29, -9, -27, 43, -37, -32, -7, 4, -1, 2, -13, -37, -52, -13, -34; /M: SY='G'; M= 11, 13, -18, 5, -67, 30, -64, 2, -11, -27, -58, -13, 1, 0, 24, -19, -18, 25, -76, -4; /M: SY='H'; M= -20, -75, -17, -23, -4, -48, 73, -42, 18, -15, 0, 21, -15, -2, -10, 11, -58, -28, -63, 68; /M: SY='T'; M= -18, -14, -40, 14, -12, -35, -19, -2, 29, 11, -54, -31, 3, 10, -1, -15, 50, -15, -76, -30; /M: SY='E'; M= 8, -73, -3, 53, -70, -65, -57, -28, 6, -26, -30, 5, -11, 30, -5, 32, -11, -12, -76, 0; /M: SY='K'; M= 29, -71, -34, -1, -65, -35, -28, -18, 49, 21, -13, -9, -21, -9, 2, -7, -27, 2, -76, -64; /M: SY='V'; M= -18, -71, -15, -6, -67, -22, 42, -49, -42, -30, -56, -6, 15, 8, -1, 40, 4, 51, -84, -63; /M: SY='Q'; M= -36, -76, 1, 34, -42, -26, -12, -50, 43, -22, -29, 4, -66, 71, 2, 20, -32, -38, -77, -63; /M: SY='A'; M= 44, -70, 0, 33, -74, -15, -61, -30, -1, -23, -62, 10, 6, 4, -25, 29, -5, -23, -79, -69; /M: SY='A'; M= 29, -28, -17, -26, -28, -35, -65, 21, -60, 28, -2, -22, -8, -61, 25, -24, -35, 23, -72, 13; /I: I=-25; MD=-63; /M: SY='Q'; M= -32, -83, 27, -17, -41, -41, -70, -3, 4, 12, -64, -18, -44, 30, -23, 17, -14, -31, -88, -72; D=-25; /I: I=-25; MI=0; MD=-63; IM=0; DM=-63; /M: SY='R'; M= 3, -72, -27, -28, -19, -40, -61, -37, -17, 44, -8, 4, -21, -21, 53, -24, -14, 0, -73, -11; /M: SY='L'; M= 18, -72, -26, -59, -63, 6, 14, -25, 23, 36, -51, 3, 20, -9, 5, -24, 9, -43, -76, -33; /M: SY='K'; M= -29, -76, -33, 23, -48, -13, -30, -34, 52, -37, -41, 26, 23, 43, 17, -7, 1, -33, -77, -66; /M: SY='H'; M= -8, -29, 5, 22, -8, 0, 46, -61, -6, -36, -11, -39, -22, 23, -23, 31, 4, 13, -75, 10; /M: SY='L'; M= -2, -74, -45, -9, -59, -38, -36, 15, 38, 41, 0, -51, 40, -23, -27, -62, -18, -6, -7, -34; /M: SY='P'; M= -5, -73, 3, 29, -67, -27, 4, -12, 2, 18, -7, -34, 36, -26, -15, 36, -15, -17, -79, -65; /M: SY='T'; M= -2, -70, -57, 17, -33, -48, -5, -28, -20, -15, -27, 16, -9, 7, 30, 23, 48, 11, -80, -63; /M: SY='Q'; M= -12, 0, -27, 27, -43, -32, -56, -52, 27, -17, -61, 9, -12, 59, 31, 23, -26, -38, -75, -14; /M: SY='H'; M= -24, -73, -8, 22, -68, -24, 69, -46, -26, -24, 54, 43, -31, 23, -11, -10, 17, 0, -84, -59; /M: SY='P'; M= 10, -74, -12, -34, -77, 43, 4, -53, -29, -46, -66, 12, 53, -21, 16, 34, -10, -44, -80, -70; /M: SY='I'; M= -18, -73, 24, -37, -40, -73, -67, 42, -36, -1, 20, -23, 17, 6, -15, -5, 6, 39, -79, -29; /I: I=-28; MD=-70; /M: SY='P'; M= -29, -18, -24, -32, -45, -93, -91, -54, -21, -51, -23, -14, 12, -19, -33, 4, -27, -33, -7, -92; D=-28; /I: I=-28; MI=0; MD=-70; IM=0; DM=-70; /M: SY='P'; M= 5, -28, -2, -19, -2, -41, 30, -70, -4, -55, -63, 42, 61, 37, -28, 6, 5, -51, -75, 12; /M: SY='M'; M= 0, -73, -63, -27, -26, 17, -59, -31, -3, -34, 54, -17, 11, 27, 40, 17, 10, -21, -73, -3; /M: SY='P'; M= -37, -23, 22, 8, -37, -67, 37, -65, 26, -21, -62, 21, 60, -4, 11, 7, -24, 0, -82, -65; /M: SY='S'; M= 13, -67, 27, -55, -70, -35, -23, -29, -59, -2, -60, -4, 4, -4, -64, 65, 41, -32, -83, -66; /M: SY='T'; M= 10, -69, -21, -41, -2, -17, -27, -48, 42, -14, -59, 38, -3, -26, -20, -18, 51, -6, -77, -33; /M: SY='E'; M= -40, -75, -40, 46, -43, 26, -60, -31, 5, -47, -66, -9, 12, -22, 42, 36, -1, -35, -78, -68; /M: SY='R'; M= -27, 19, -2, 26, -43, -24, -19, -10, 6, -26, -7, 23, -68, -34, 45, -8, 34, 7, -81, -64; /M: SY='S'; M= -2, -70, -7, -10, -24, -27, 1, -35, 13, -31, -63, 21, 17, 2, -31, 65, 6, -21, -80, -64; /M: SY='S'; M= -13, -70, -14, 13, -15, -4, 20, -27, -26, 7, -56, -36, -5, -9, -13, 44, 32, 5, -18, -61; /M: SY='N'; M= -28, 4, -39, -14, -24, -19, -12, -59, 1, -12, -7, 52, -21, 27, -17, 50, -17, 12, -80, -31; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 20 in 20 different sequences |
| Number of true positive hits | 20 in 20 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | DMAP1-binding |
| Version [info] | 2 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
20 sequences
DI2BA_DANRE (Q6NVJ5), DIP2A_HUMAN (Q14689), DIP2A_MOUSE (Q8BWT5), DIP2B_HUMAN (Q9P265), DIP2B_MOUSE (Q3UH60), DIP2C_HUMAN (Q9Y2E4), DIP2_DROME (Q9W0S9), DNMT1_BOVIN (Q24K09), DNMT1_CHICK (Q92072), DNMT1_HUMAN (P26358), DNMT1_MOUSE (P13864), DNMT1_PARLI (Q27746), DNMT1_RAT (Q9Z330), GNPTA_DANRE (Q5RGJ8), GNPTA_HUMAN (Q3T906), GNPTA_MOUSE (Q69ZN6), GNPTG_BOVIN (Q58CS8), GNPTG_HUMAN (Q9UJJ9), GNPTG_MOUSE (Q6S5C2), YO093_YEAST (Q12275)» more
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| PDB [Detailed view] |
3 PDB
7S05; 7S06; 8V9U |