PROSITE entry PS52035
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General information about the entry
Entry name [info] | PEPTIDASE_M14 |
Accession [info] | PS52035 |
Entry type [info] | MATRIX |
Date [info] |
24-JAN-2024 CREATED;
24-JAN-2024 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
PROSITE Doc. [info] | PDOC52035 |
Associated ProRule [info] | PRU01379 |
Name and characterization of the entry
Description [info] | Peptidase family M14 domain profile. |
Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=290; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=285; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2143202; R2=0.0063441; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1385; N_SCORE=11.0; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=676; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-30; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='Y'; M= -22, -79, 21, 18, -47, 5, 12, -41, 25, -73, -66, -16, -41, 18, 29, 8, -11, -50, -71, 46; /M: SY='Y'; M= -72, -86, -69, -45, -37, -77, 48, -3, -37, -61, -56, -37, 61, -63, -66, -67, -66, -65, -45, 109; /M: SY='H'; M= -34, -80, -40, -59, 13, -73, 106, -70, -59, -46, -30, 15, -76, 37, -12, -60, -24, -47, -65, 70; /M: SY='T'; M= -57, -72, -4, -21, -77, -62, 12, -73, -2, -77, -69, 51, 38, -54, 10, 48, 51, -54, -88, -69; /M: SY='Y'; M= -60, 15, -11, -28, 9, -79, -23, -54, -45, 32, 8, -9, -82, -8, -41, -69, -66, -59, 56, 95; /M: SY='E'; M= -10, -76, 19, 59, -53, -33, -58, -79, 0, -78, -71, 24, 5, 29, -56, 42, -3, -74, -83, -71; /M: SY='E'; M= -13, -77, 46, 54, -51, -32, -60, -52, -33, -70, -13, -16, -66, 36, 6, -7, 20, 7, -85, -69; /I: I=-33; MI=0; MD=-84; IM=0; DM=-84; /M: SY='M'; M= -42, -4, -83, -79, -29, -58, 34, 66, -76, 27, 73, -74, -48, -71, -76, -56, -24, -6, -79, -57; D=-33; /I: I=-33; DM=-84; /M: SY='Q'; M= -28, -77, 6, 36, -62, -46, 3, -32, -31, -25, 13, 1, -71, 46, 11, -11, -15, 17, -71, 45; D=-33; /I: I=-33; DM=-84; /M: SY='A'; M= 30, -25, 13, 19, -77, -38, 11, -33, 12, -57, 13, 10, 19, 19, 4, 20, -7, -52, -82, -68; /M: SY='W'; M= -10, -81, -22, -10, 48, -75, 9, -41, -13, -2, -20, -73, -77, -65, -31, -30, -36, -31, 125, 46; /M: SY='M'; M= -44, -71, -82, -76, -30, -82, -66, 29, -73, 58, 89, -76, -78, -68, -73, -71, 9, -28, -71, 4; /M: SY='R'; M= -10, -78, 36, 16, -75, -34, -19, -31, 29, -24, -32, 8, -70, 32, 52, -5, -34, -43, -80, -28; /M: SY='Q'; M= -9, -75, -6, 11, -38, -14, -21, -34, 12, 16, -28, -10, -12, 43, 24, 7, -2, -22, -77, -34; /M: SY='L'; M= -29, -71, -83, -76, 6, -84, -72, 24, -58, 57, 47, -77, -80, -70, -12, -71, -18, 38, -74, -39; /M: SY='A'; M= 48, -70, -4, 21, -71, -47, -28, -17, -43, -45, -37, 13, -69, 34, -51, -8, 10, 23, 5, -40; /M: SY='S'; M= 3, -73, -16, 35, -51, -20, -29, -22, 3, -42, -15, 16, -66, 33, 3, 52, 1, -66, -81, -67; /M: SY='M'; M= -10, -76, 15, 46, -72, -70, -27, -45, 17, -17, 55, 13, -32, 20, 30, -5, -29, -45, -80, -39; /M: SY='Y'; M= -38, 58, -64, -44, 55, -36, 63, -54, -34, -61, -24, 45, 11, -45, -65, -44, -36, -39, -60, 65; /M: SY='P'; M= -14, -80, -12, -35, -78, -13, -66, -48, -33, -50, -23, -11, 96, -12, -37, 30, -12, -32, -81, -40; /I: I=-19; MD=-49; /M: SY='D'; M= -37, -44, 36, 12, -19, -19, 23, -81, -25, -69, -73, 29, 2, 16, 6, 31, 0, -78, 22, -67; D=-19; /I: I=-19; MI=0; MD=-49; IM=0; DM=-49; /M: SY='H'; M= -69, -77, -78, -58, 16, -84, 50, 44, -72, 38, 33, -20, -38, -39, -35, -72, -64, 5, -68, 38; D=-19; /I: I=-19; DM=-49; /M: SY='V'; M= 26, 30, -35, -71, 11, -24, -74, 6, -70, -28, -24, -66, -35, -70, -73, -5, 32, 54, -77, 0; /M: SY='R'; M= -45, -75, -57, 16, -39, -33, 30, -74, 19, -40, -27, -19, -68, 24, 53, 44, 23, -70, -78, -11; /I: I=-45; MD=-115; /M: SY='R'; M= -65, -21, -71, -46, -43, -35, 6, 7, 31, 27, 16, -65, -22, 3, 36, -64, 4, 12, -75, 7; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='Y'; M= -62, -76, -8, 31, 12, -46, 12, 35, -22, -24, -29, -63, -72, -40, 4, -1, 6, 19, -68, 46; /M: SY='S'; M= 2, -71, -2, 7, -25, -36, 28, -57, -6, -27, -27, 35, -19, 22, -43, 45, 4, 7, -82, -42; /M: SY='I'; M= -20, -74, -37, -50, -48, -29, -73, 69, -75, 40, -40, -37, -78, -71, -77, -47, -38, 20, -71, 26; /M: SY='G'; M= -24, 58, -33, -76, -24, 90, -73, -82, -48, -34, -71, -55, -73, -70, -77, -53, -67, -56, -77, -75; /M: SY='R'; M= -49, -76, -26, -9, -71, -23, 18, -17, 48, -48, -21, -7, -69, 24, 49, 8, 18, -17, -77, -5; /M: SY='S'; M= -46, -65, -57, -40, -74, -56, -62, -71, -58, -74, -69, -47, -26, -24, -64, 91, 61, -63, -85, -68; /M: SY='Y'; M= -25, -73, -74, -12, 53, -51, 39, -37, -71, 21, -47, -72, -80, -69, -70, -44, -51, 45, -58, 66; /M: SY='E'; M= -13, -79, 15, 82, -31, -4, -57, -75, -27, -4, -65, -39, -64, 40, -13, -32, -62, -72, -79, -68; /M: SY='G'; M= -28, -77, -34, -70, -54, 90, -20, -87, -4, -72, -73, -2, -70, -30, -43, -10, -48, -81, -75, -35; /M: SY='R'; M= -30, -79, -51, -56, -27, -72, 8, -74, -15, -19, -61, 42, -76, -5, 92, -41, -29, -72, -74, 13; /M: SY='P'; M= -33, -80, 37, 23, -80, -46, -5, -32, 16, -77, -27, 11, 73, -17, -9, 5, 11, -72, -84, -52; /M: SY='I'; M= -66, 12, -86, -80, 2, -87, -76, 69, -52, 47, 45, -79, -80, -74, -77, -75, -61, 17, -74, -55; /M: SY='W'; M= -46, -81, 7, -31, -18, -73, -46, -29, 5, -5, -58, 2, 53, -61, -49, -25, -16, -37, 82, 79; /M: SY='V'; M= 34, -26, -75, -28, -52, -8, -68, -19, -47, 31, -4, -72, -76, -67, -71, -31, -40, 46, 2, 40; /M: SY='L'; M= -66, -72, -85, -78, 7, -86, -70, 21, -51, 71, 33, -81, -83, -72, -75, -76, -62, 20, -70, 5; /M: SY='K'; M= -62, -77, -55, 30, -74, -73, 14, -73, 67, -54, -64, -53, -10, 24, 32, -54, 41, -39, -77, -11; /M: SY='I'; M= -19, -73, -83, -79, 30, -83, -77, 68, -51, 22, 22, -75, -78, -74, -77, -20, -30, 38, -72, -53; /M: SY='S'; M= -36, -71, -39, -62, -53, 49, -65, -76, -23, -78, -71, -17, -3, -22, -41, 67, 39, -70, 26, -69; /I: I=-10; MD=-26; /M: SY='T'; M= 21, -72, 36, -45, -52, 10, -63, -68, 13, -73, -67, 21, -69, -20, 1, 14, 38, -2, -83, -31; D=-10; /I: I=-10; MD=-26; /M: SY='P'; M= -42, 6, -17, -39, -43, 12, 28, -79, 16, -78, 0, 30, 43, -11, 12, 4, 7, -77, 24, -38; D=-10; /I: I=-10; MD=-26; /M: SY='P'; M= -51, -84, -1, -11, -83, 23, 28, -40, -7, -44, -71, -1, 75, -63, -30, 14, -42, -34, -87, -76; D=-10; /I: I=-10; MD=-26; /M: SY='G'; M= -15, -83, -26, -5, -33, 48, -54, -88, -23, -87, -54, 5, -14, 0, -26, 31, -7, -82, -88, -79; D=-10; /I: I=-10; MD=-26; /M: SY='E'; M= -41, -89, -28, 23, -89, -72, -5, -36, -19, -35, -42, 23, -50, -15, -59, 13, 16, -24,-102, -84; D=-10; /I: I=-10; MD=-26; /M: SY='H'; M= -40, -97, 19, -46, -54, -45, 60, -45, -40, -37, -82, 12, 15, -75, -13, -14, -42, -61,-106, -53; D=-10; /I: I=-10; MI=0; MD=-26; IM=0; DM=-26; /M: SY='P'; M= 14, -90, -72, 25, -88, -11, -78, -63, -13, -26, -77, -75, 43, -67, 14, -27, -21, -47, -91, -57; D=-10; /I: I=-10; DM=-26; /M: SY='N'; M= 3, -45, -15, -11, -81, 34, 10, -69, -26, -35, -29, 43, 20, -47, -3, 24, -40, -69, -87, -75; D=-10; /I: I=-10; DM=-26; /M: SY='K'; M= -64, -79, -54, 37, -76, -73, -6, -49, 72, -32, -64, -7, -67, -29, 60, -24, -41, -40, -78, -66; /M: SY='P'; M= -51, -85, -62, -23, -78, -70, -63, -74, 51, -34, -67, -5, 98, -55, 20, -36, -60, -76, -77, -22; /M: SY='A'; M= 42, -71, -58, 37, -69, -37, -63, -13, 10, -65, -18, -30, -40, -23, 2, 9, 20, 8, -76, 8; /M: SY='I'; M= -62, -73, -85, -81, 32, -34, -81, 69, -78, 5, -22, -77, -79, -40, -79, -71, -59, 60, -73, -34; /M: SY='W'; M= -68, -78, -82, -71, 52, -81, 13, 3, 22, 21, 2, -74, -79, -67, -7, -72, -66, 23, 110, -42; /M: SY='I'; M= -66, -75, -84, -80, 24, -86, -67, 59, -76, 33, 53, -78, -80, -72, -75, -73, -49, 20, -61, 57; /M: SY='D'; M= -58, -72, 53, -15, -68, -60, 2, 24, -39, -31, -58, -16, -69, 7, -66, 28, 45, 27, -88, -65; /M: SY='C'; M= 61, 71, -68, -68, -78, 54, -72, -75, -67, -58, -68, -58, -71, -65, -73, 14, -19, -64, -80, -75; /M: SY='G'; M= -38, -76, -59, -66, -79, 74, -27, -82, -54, -42, -70, 46, -72, -30, 46, -8, -21, -78, -79, -72; /M: SY='M'; M= -37, -72, -78, -73, 32, -79, -13, 56, -70, -18, 60, -55, -75, 14, -72, 6, -12, 41, -73, -52; /M: SY='H'; M= -71, -82, -55, -55, -67, -73, 146, -87, -60, -69, -55, -44, -72, -49, -54, -60, -69, -86,-101, -8; /M: SY='A'; M= 61, -27, -29, -64, -81, 53, -71, -76, -66, -78, -69, -60, 59, -64, -73, -6, -58, -68, -78, -77; /M: SY='R'; M= -63, -79, 15, -13, -77, 34, -55, -83, -40, -80, -70, 54, -73, -49, 81, -42, -29, -79, 2, -23; /M: SY='E'; M= -36, -82, -33, 109, -84, -77, -55, -85, -43, -77, -74, -58, -57, -36, -53, -57, -29, -77, -82, -75; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='W'; M= -19, -81, -76, -69, -56, -70, 23, -65, -67, -69, -67, -35, 25, -66, -72, 5, 48, -2, 142, -45; /M: SY='I'; M= 11, -73, -74, -74, -57, -75, -73, 67, -71, 10, 24, 24, 12, -69, -75, -23, -56, 30, -79, -62; /M: SY='S'; M= 27, -68, -62, -65, -77, 56, -67, -75, -63, -77, -70, -51, -66, -59, -69, 62, 41, -67, -80, -72; /M: SY='P'; M= -49, -76, -7, -5, -74, -70, -3, -25, -32, -54, -62, -58, 57, 14, 41, 33, 29, 18, -83, -68; /M: SY='W'; M= 39, -77, -60, 47, -4, -42, -11, -71, -58, -69, -1, -64, 5, 18, -63, 23, -60, -45, 103, -28; /I: I=-45; MI=0; MD=-115; IM=0; DM=-115; /M: SY='T'; M= -23, -69, -73, -43, 42, -4, -71, 3, -70, 21, 34, -65, -73, -69, -73, 3, 49, 23, -9, -53; /M: SY='C'; M= 7, 70, -81, -76, -12, -21, -72, -12, -74, 40, 69, -73, -79, -71, -75, -65, -15, 31, -79, -60; /M: SY='L'; M= -44, -6, -63, 8, -59, -75, -5, 8, 2, 45, -15, 18, -73, 44, -60, -13, 13, -12, -78, -40; /M: SY='W'; M= -21, 8, -71, -71, -21, 36, 32, -54, -41, -30, -62, -10, -77, -28, -5, -35, -31, -62, 108, 75; /M: SY='F'; M= 5, -71, -82, -77, 72, -79, -72, 26, -75, 41, -2, -75, -79, -75, -76, -56, 12, -2, 1, -43; /M: SY='A'; M= 46, -69, -79, -73, -31, -47, -74, 37, -72, 43, 15, -73, -76, -69, -55, -33, -43, 24, -76, -61; /M: SY='W'; M= -40, -80, 24, 35, -45, -15, 4, -79, 20, -75, -67, 37, -69, 35, 37, -14, -60, -77, 38, 35; /I: I=-16; MD=-41; /M: SY='F'; M= -64, -78, -11, 32, 50, -33, 5, -54, 12, -43, -62, -23, -72, 48, -8, 16, -22, -69, -14, 43; D=-16; /I: I=-16; MD=-41; /M: SY='L'; M= -15, -37, -87, -81, 10, -86, -73, 36, -80, 68, -6, -83, -84, -75, -79, -76, -65, -13, -71, 4; D=-16; /I: I=-16; MD=-41; /M: SY='C'; M= -13, 69, -81, -76, -45, -59, -78, 23, -75, 28, 3, -73, -33, -18, -72, -65, 29, 36, -85, -66; D=-16; /I: I=-16; MD=-41; /M: SY='S'; M= -11, -33, -2, 18, -77, -6, -16, -51, -17, -25, -9, 1, -16, 33, 4, 37, 26, -69, -84, -43; D=-16; /I: I=-16; MD=-41; /M: SY='N'; M= -37, -48, 5, 19, -40, 3, 4, -87, -25, -87, -79, 53, -20, -5, -11, 17, -4, -83, 6, -46; D=-16; /I: I=-16; MD=-41; /M: SY='Y'; M= -72,-102, -65, -96, 24, -56, -2, -78, -90, -36, -72, -93,-105, -87, -87, -89, -88, -83, -21, 97; D=-16; /I: I=-16; MD=-41; /M: SY='G'; M= -39, -26, -25, -46,-100, 44, -85, -72, 5, -42, -89, -7, -92, -5, -13, -61, -49, -95,-100, -93; D=-16; /I: I=-16; MI=0; MD=-41; IM=0; DM=-41; /M: SY='K'; M= -74, -91, 17, -22, -46, 4, -71, -64, 42, -56, -79, -8, -81, 27, 8, -16, -9, -86, -89, -25; D=-16; /I: I=-16; DM=-41; /M: SY='D'; M= -65, -32, 72, 1, -86, -31, -18, -44, -41, -85, -79, 55, -74, -11, -66, 35, -41, -53, -98, -76; D=-16; /I: I=-16; DM=-41; /M: SY='P'; M= -7, -82, -31, -8, -44, -40, -39, -22, 11, -56, -69, -30, 75, -12, -14, 22, 6, -34, -84, -75; D=-16; /I: I=-16; DM=-41; /M: SY='R'; M= 14, -78, 6, 8, -74, -72, 26, -28, -31, -54, -36, -44, -36, -4, 47, 12, 17, -4, 23, -33; D=-16; /I: I=-16; DM=-41; /M: SY='I'; M= 35, -74, -42, -25, -18, -53, -39, 51, -73, -19, 47, -45, -38, -70, -76, -33, -44, 29, -78, -15; D=-16; /I: I=-16; DM=-41; /M: SY='T'; M= -11, -38, -49, -58, -74, -20, -11, -36, 4, -42, -62, -8, -70, 46, 22, -24, 68, -2, -84, -40; D=-16; /I: I=-16; DM=-41; /M: SY='K'; M= 1, -77, 9, 25, -76, -69, -12, -49, 37, -19, -6, 21, -35, 18, 32, 4, -9, -47, -83, -68; D=-16; /I: I=-16; DM=-41; /M: SY='L'; M= -53, -73, -87, -80, 4, -55, -72, 15, -80, 78, -1, -84, -86, -74, -78, -78, -66, -23, -71, -17; D=-16; /I: I=-16; DM=-41; /M: SY='L'; M= -21, -74, -82, -74, 9, -84, -70, 7, -64, 55, -42, -77, -83, -68, 39, -72, -37, 27, -73, -4; D=-16; /I: I=-16; DM=-41; /M: SY='E'; M= -64, -79, 56, 60, -83, -67, 10, -83, 8, -81, -73, 55, -66, 23, 13, -16, -47, -80, -88, -70; /M: SY='N'; M= -42, -13, 21, -2, -75, -40, 18, -50, 36, -33, -17, 49, -69, 8, 24, 24, 12, -52, -84, -44; /M: SY='F'; M= -23, -71, -76, -73, 62, -78, -65, -34, -67, 18, 46, -68, -77, -69, -2, -33, 46, 5, 5, 35; /M: SY='D'; M= -64, -29, 78, -2, -75, -70, -30, 3, -29, -70, -67, 25, -71, -54, 41, -17, 0, 5, -90, -32; /M: SY='W'; M= -72, -78, -88, -83, 79, -86, 4, 60, -79, 10, -25, -79, -82, -79, -78, -76, -67, -25, 85, -17; /M: SY='Y'; M= -66, -79, -34, -65, 14, -76, 72, 5, 28, -26, -53, -62, -76, -60, -58, -2, -62, 15, 40, 78; /M: SY='I'; M= -65, -74, -87, -82, 23, -89, -80, 69, -80, 42, -26, -81, -81, -77, -80, -75, -60, 44, -73, -53; /M: SY='M'; M= -44, -72, -81, -15, -1, -85, -74, 42, -75, 45, 58, -78, -79, -71, -75, -72, -45, 48, -76, -56; /M: SY='P'; M= -68, -92, -70, -59, -34, -72, -72, -23, -66, -33, -67, -76, 121, -69, -77, -66, -61, -74, -79, -49; /M: SY='M'; M= -56, 19, -45, -67, -62, -70, -21, -17, -64, -16, 72, 18, -73, -20, -24, 39, 26, 45, -85, -63; /M: SY='M'; M= -9, -70, -81, -76, -4, -80, -69, 11, -73, 47, 74, -75, -78, -70, -74, -67, 16, 34, -74, -8; /M: SY='N'; M= -63, -69, -37, -59, -79, -52, -45, -78, -50, -85, -72, 122, -75, -52, -58, -11, -48, -80, -98, -74; /M: SY='P'; M= -67, -90, -71, -59, -81, -72, -73, -2, -34, -75, -37, -75, 118, -69, -76, -66, -60, -6, -81, -80; /M: SY='D'; M= -69, -82, 114, -35, -34, -67, -56, -85, -57, -84, -83, -25, -69, -57, -66, -57, -12, -82, 6, -69; /M: SY='G'; M= -33, -78, -66, -76, -85, 100, -72, -92, -71, -87, -76, -52, -70, -22, -78, -51, -70, -85, -76, -79; /M: SY='Y'; M= -48, -19, -74, -75, 49, -34, -54, -47, -69, -38, -52, -9, -83, -69, -31, -19, -61, 39, -46, 98; /M: SY='E'; M= 12, -28, -9, 52, 0, -75, -24, 34, -29, -55, -55, -35, -70, -6, -65, -19, -41, 42, -78, -28; /M: SY='Y'; M= -36, -77, -70, -41, 34, -78, 21, -20, -4, 6, -51, -2, -80, -62, 19, -66, -26, 5, 7, 87; /I: I=-13; MD=-33; /M: SY='T'; M= 17, -71, -9, -67, -77, 50, -72, -40, -66, -74, -69, -54, -69, -65, -52, 22, 64, -20, -85, -73; D=-13; /I: I=-13; MD=-33; /M: SY='W'; M= -11, -82, -66, -65, 8, -71, 69, -5, -37, -32, -62, 47, -77, 29, -26, -47, -22, -70, 111, -8; D=-13; /I: I=-13; MD=-33; /M: SY='T'; M= -19, -83, -28, 37, -85, -45, 26, -81, -14, -23, -75, -6, -76, -19, -70, 17, 43, -76, -96, -77; D=-13; /I: I=-13; MD=-33; /M: SY='T'; M= -65, -91, -49, -30, -94, 5, -10, -88, 4, -89, 6, 5, -43, 4, -35, 8, 31, -44,-101, -86; D=-13; /I: I=-13; MD=-33; /M: SY='D'; M= -81, -96, 63, -35,-103, 12, -74,-102, -75, -93, -96, 51, -12, -57, -84, -39, -75,-101,-112, -93; D=-13; /I: I=-13; MI=0; MD=-33; IM=0; DM=-33; /M: SY='R'; M= -38, -97, -35, -72, -41, -45, -74, -92, -12, -52, -81, -39, -65, -65, 77, -21, -34, -55, -93, -43; D=-13; /I: I=-13; DM=-33; /M: SY='M'; M= -78, -87, -93, -36, 9, -51, -82, -19, -87, 33, 63, -66, -41, -82, -87, -8, -42, -8, -87, -36; D=-13; /I: I=-13; DM=-33; /M: SY='W'; M= -79,-103, -96, -88, -56, 32, -88, -86, -81, -83, -81, -87, -88, -18, -84, -81, -90, -94, 144, 42; D=-13; /I: I=-13; DM=-33; /M: SY='R'; M= -68, -84, -64, -53, -77, -78, -12, -83, -7, -56, -65, -22, -77, -32, 111, -44, -66, -77, -78, -64; /M: SY='K'; M= -4, 61, -43, -29, -9, -51, -64, -74, 73, -73, -67, 2, -70, -18, -45, -11, 17, -70, 54, 1; /M: SY='N'; M= -58, -22, -10, -59, -75, -56, -52, -72, -54, -44, -68, 100, -70, -55, -62, 29, 50, -70, -94, -71; /M: SY='R'; M= 32, -76, -66, -22, -68, -70, -10, -11, -18, 3, -58, -47, -30, -51, 80, -4, -29, -61, -76, -13; /M: SY='Q'; M= 4, -27, -33, -22, -43, -61, -6, -70, -29, -52, -5, 44, -69, 66, 4, 52, -2, -34, -81, -33; /I: I=-19; MI=0; MD=-49; IM=0; DM=-49; /M: SY='G'; M= -9, -76, -62, -72, -83, 95, -68, -88, -67, -85, -74, 23, -69, -15, -74, -41, -65, -82, -76, -77; /M: SY='V'; M= 1, -71, -30, 5, 24, -76, -29, 29, -34, -20, -51, -65, -72, -32, 12, -51, 39, 47, -75, -18; /M: SY='D'; M= -68, -80, 112, -15, -87, -64, -53, -86, -54, -85, -82, 38, -68, -54, -52, -55, -57, -83,-103, -72; /M: SY='L'; M= -37, -17, -81, -72, -49, -44, -70, -10, -75, 77, -36, -80, 55, -71, -76, -63, -63, -46, -74, -60; /I: I=-10; MD=-26; /M: SY='N'; M= -65, -71, 39, -54, -43, -54, -46, -79, -51, -85, -73, 116, -74, -52, -59, -48, -50, -80, -97, -72; D=-10; /I: I=-10; MD=-26; /M: SY='R'; M= -51, -84, -12, -33, -78, -77, 6, -84, -17, -77, -66, -31, -76, -43, 109, -61, -30, -77, -79, -64; D=-10; /I: I=-10; MD=-26; /M: SY='N'; M= -14, -72, 27, -12, -28, -16, 2, -76, -52, -78, -13, 92, -71, 39, -59, 9, -14, -75, -88, -68; D=-10; /I: I=-10; MD=-26; /M: SY='W'; M= -79, -86, -93, -85, 89, -82, -78, -63, -78, -57, -63, -29, -87, -82, -79, -80, -78, -70, 134, 32; D=-10; /I: I=-10; MD=-26; /M: SY='P'; M= -3, -83, 33, -48, -42, 15, -67, -76, -13, -45, -17, 1, 68, -6, -23, -37, 6, -54, -83, -15; D=-10; /I: I=-10; MD=-26; /M: SY='D'; M= 23, -79, 44, -35, 41, -74, -67, -43, -72, -23, -29, -64, -80, -70, -75, 10, 0, -37, -71, 42; D=-10; /I: I=-10; MD=-26; /M: SY='Q'; M= -46, -92, -69, 30, -86, 5, 23, -81, 10, 3, -72, -21, -83, 38, -68, -20, -75, -41, -93, -79; D=-10; /I: I=-10; MD=-26; /M: SY='W'; M= -97,-111, -34, -96, 15, -94, -10, -95, -91, -92, -93, 18,-102, -92, -95, -94, -44,-103, 133, -57; D=-10; /I: I=-10; MD=-26; /M: SY='W'; M= -42, 36, 18, -26, -98, 16, -91,-101, -86,-101, -54, -1, -96, -85, -47, -16, -24, -58, 53, -91; D=-10; /I: I=-10; MI=0; MD=-26; IM=0; DM=-26; /M: SY='G'; M= -82, 16, -48, 8,-101, 30, -92, -62, -18, -84, -30, -42, -94, -82, -50, -8, -25, -98, 29, -95; D=-10; /I: I=-10; DM=-26; /M: SY='N'; M= -30, -99, -39, 0, -94, -24, -87, -9, -32, -88, -84, 9, -4, -22, -29, -19, -30, -1,-104, -40; D=-10; /I: I=-10; DM=-26; /M: SY='G'; M= -34,-100, -54, -89,-102, 56, -88, -71, -58,-104, -94, -12, 3, -46, -8, -19, -85, -89, -99, -58; D=-10; /I: I=-10; DM=-26; /M: SY='A'; M= 31, -88, -81, -84, -46, -37, -19, -66, -51, -91, -53, 19, -90, -80, -87, 17, 22, -52,-104, -89; D=-10; /I: I=-10; DM=-26; /M: SY='S'; M= -40, -93, -80, -80, -98, -31, 21, -99, -75, -99, -90, -8, -12, -44, 9, 55, -10, -92,-106, -88; D=-10; /I: I=-10; DM=-26; /M: SY='S'; M= -45, -94, -11, -47, -93, -47, -19, -61, -50, -53, -51, 6, -1, -36, -19, 35, 10, -77,-103, -24; D=-10; /I: I=-10; DM=-26; /M: SY='N'; M= -56, -93, 2, -35, -54, -52, -8, -57, -66, -30, -86, 62, -94, -43, -63, 15, -44, -53,-110, -88; D=-10; /I: I=-10; DM=-26; /M: SY='P'; M= -25, -11, -60, -54,-105, -56, 5, -97, -54,-102, -91, -89, 85, -62, -25, -38, -82, -67,-104, -98; D=-10; /I: I=-10; DM=-26; /M: SY='C'; M= -83, 110, -24, -74, -93, -61, -11, -20, -94, -67, -87, -38,-106, -33, -99, -20, -82, -53,-118, -96; D=-10; /I: I=-10; DM=-26; /M: SY='S'; M= -42, -91, -16, -80, -33, -80, -84, -85, -83, -36, -41, -61, 22, -78, -88, 62, -52, -34,-100, -38; D=-10; /I: I=-10; DM=-26; /M: SY='E'; M= -81, -98, 33, 60, -48, -90, -31, -48, -21, -65, -87, -8, -38, -41, -12, -49, -50, -57,-100, -52; D=-10; /I: I=-10; DM=-26; /M: SY='T'; M= -52, -86, -14, -38, -81, -37, -81, -22, -44, -42, -76, 0, -29, -77, -47, 4, 57, -14, -7, -15; D=-10; /I: I=-10; DM=-26; /M: SY='Y'; M= -71, -92, -82, -83, 32, -66, 0, -48, -27, -41, -64, -25, -42, -26, -75, -63, -56, -74, -50, 101; D=-10; /I: I=-10; DM=-26; /M: SY='C'; M= 11, 49, -7, -34, -43, -7, 43, -78, -68, -21, -72, -32, -19, -39, 19, -9, -11, -30, -93, -49; D=-10; /I: I=-10; DM=-26; /M: SY='G'; M= -64, -87, -25, -37, -86, 72, -73, -93, -10, -54, -80, 12, -40, -3, -39, -21, -73, -89, -19, -15; D=-10; /I: I=-10; DM=-26; /M: SY='P'; M= -12, -83, 26, 8, -53, -70, -1, -29, -17, -41, 7, -21, 79, -32, -12, 4, -12, -60, 33, -42; D=-10; /I: I=-10; DM=-26; /M: SY='S'; M= 11, -71, 10, 16, -19, -18, -25, -25, 6, -14, -62, 41, -68, -10, -59, 42, 6, -46, 11, 2; /M: SY='P'; M= 48, -75, -26, -8, -54, -12, -67, -66, 0, -43, -64, -23, 81, -34, -14, -26, -36, -11, -79, -73; /M: SY='F'; M= -34, -75, 12, 45, 59, -21, -22, -33, -17, -5, -39, 19, -36, 2, -62, -10, -3, -30, 22, -25; /M: SY='S'; M= -3, -70, -16, 14, -59, -29, -62, -42, -46, 7, -59, -55, -38, 2, 18, 66, 8, 1, -81, -65; /M: SY='E'; M= 19, -12, -50, 65, -12, 10, 58, -73, -52, -43, -64, -56, -65, 32, -21, 11, -59, -30, -78, -37; /M: SY='P'; M= -37, -81, -67, -58, -76, -70, -70, -23, -5, -57, -27, -40, 103, 3, -54, -17, 16, 15, -13, -74; /M: SY='E'; M= -42, -1, -36, 101, -82, -73, -56, -82, -45, -76, -72, -56, -58, -4, -54, 4, 9, -74, -82, -73; /M: SY='T'; M= 21, -66, -69, -68, -63, -46, -74, 26, -66, -30, -33, -60, -68, -66, -71, 9, 73, 45, -84, -65; /I: I=-31; MI=0; MD=-79; IM=0; DM=-79; /M: SY='K'; M= -5, -79, -11, -40, -64, -72, 7, -10, 64, -21, -26, -57, -71, 9, 48, -31, -61, -32, 60, 22; /M: SY='A'; M= 67, -68, 4, -40, -39, -6, -24, -39, -61, -27, -60, -44, -70, 9, -18, 20, -38, -1, -74, 10; /M: SY='V'; M= -7, -70, -81, -76, 5, -80, -44, 42, -73, 34, 35, -46, -77, -72, -47, -46, -5, 55, -12, -55; /M: SY='M'; M= 31, -17, -70, -62, -38, -56, -18, 26, 26, -2, 44, -63, -72, -29, 33, -15, -11, 6, -75, -13; /M: SY='D'; M= -10, -76, 62, 20, -81, -46, -11, -78, 11, -59, -69, 44, -67, 55, -26, 24, -26, -75, -85, -47; /M: SY='W'; M= -35, -79, -82, -48, 68, -77, 26, -28, -44, 15, 19, -20, -43, -50, -56, -72, -69, -33, 122, 27; /M: SY='I'; M= 13, -72, -82, -77, -14, -80, -75, 68, -74, 33, 55, -75, -41, -71, -76, -67, -19, 19, -75, -57; /M: SY='R'; M= -9, -33, -13, 6, -32, -57, 42, -28, 37, -6, 0, -6, -70, 20, 54, -42, 5, -40, -78, -35; /M: SY='S'; M= -5, -73, -10, 17, -71, -21, -56, -72, 20, -17, -64, 41, -68, -4, 37, 45, -4, -68, -78, -2; /I: I=-4; MD=-9; /M: SY='H'; M= -82, -93, -78, -9, -75, -92, 70, -23, -40, 19, -22, -5, -55, 2, -25, -38, -43, -32, -96, -12; D=-4; /I: I=-4; MI=0; MD=-9; IM=0; DM=-9; /M: SY='N'; M= -38, -97, -50, -2, -94, -19, -80, -39, 26, -21, -81, 32, -91, -7, -14, -77, -45, -40,-102, -89; D=-4; /I: I=-4; DM=-9; /M: SY='N'; M= 9, -32, -26, -14, -11, 10, -12, 15, 0, -41, -59, 29, -70, 17, 22, 12, 9, -6, -76, -14; /M: SY='P'; M= -59, -26, 0, 13, -79, 21, 33, -79, 19, -62, -68, 30, 39, 29, 17, 21, -9, -67, -82, -68; /M: SY='F'; M= -67, 26, -81, -45, 75, -83, -74, 52, -72, -24, -4, -75, 35, -76, -15, -70, -41, 27, -63, -44; /M: SY='V'; M= 11, -72, 33, -35, -44, -58, -1, -10, 46, -8, -16, -58, -71, -28, -11, -30, -28, 47, -80, -36; /M: SY='L'; M= 35, 19, -76, -72, 15, 16, -70, -13, -70, 40, 32, -69, -76, -68, -43, -25, -18, -3, 27, -13; /M: SY='Y'; M= -25, -74, -73, -72, 66, -34, 26, -14, -69, -18, -1, -66, -78, -66, -68, 31, -59, -1, -49, 84; /M: SY='C'; M= 17, 51, -81, -76, -24, -35, -75, 48, -75, 46, -10, -74, -78, -72, -77, -66, -22, 25, -76, -34; /M: SY='D'; M= -9, -72, 86, -44, -80, -60, -57, -66, -56, -78, -73, 42, -66, -55, -64, 33, 46, -70, -94, -70; /M: SY='F'; M= -68, 16, -84, -36, 57, -84, -70, 33, -76, 54, 49, -79, -81, -73, -75, -75, -64, -16, 41, -8; /M: SY='H'; M= -70, -82, -3, -53, -70, -40, 144, -87, -59, -70, -56, -23, -71, -24, -54, -59, -68, -86,-103, -40; /M: SY='S'; M= 4, -70, -32, 19, -78, 58, -65, -76, -60, -78, -71, -50, -65, -55, -67, 67, 8, -37, -80, -72; /M: SY='Y'; M= -66, -81, 18, -64, 17, 35, 69, -69, -65, -64, -59, -58, -13, -11, -65, -60, -34, -71, 8, 95; /I: I=-5; MI=0; MD=-13; IM=0; DM=-13; /M: SY='S'; M= 7, -74, -11, 5, -80, 9, -31, -81, -19, -82, -75, 2, -1, -45, -66, 73, -31, -74, -17, -36; D=-5; /I: I=-5; DM=-13; /M: SY='Q'; M= -64, -82, -42, -2, -77, -6, -3, -68, -20, 2, -11, 33, -75, 87, -19, -14, -63, -15, -82, -38; D=-5; /I: I=-5; DM=-13; /M: SY='M'; M= -63, -4, -33, -31, -58, -82, -25, -4, -50, 27, 53, -71, -79, 33, -1, -23, -45, 49, -79, -3; D=-5; /I: I=-5; DM=-13; /M: SY='I'; M= 20, -74, -84, -79, 48, -33, -77, 48, -77, 22, 2, -40, -80, -76, -79, -68, -47, 23, 3, -52; D=-5; /I: I=-5; DM=-13; /M: SY='M'; M= -34, 28, -75, -74, -16, -50, -66, -3, -71, 49, 65, 23, -80, -54, -50, 7, -20, -22, -77, -9; D=-5; /I: I=-5; DM=-13; /M: SY='Y'; M= -31, -82, -75, -77, 38, -37, -50, -52, -69, -58, -56, -16, -84, -68, -44, -40, -18, -23, 59, 110; D=-5; /I: I=-5; DM=-13; /M: SY='P'; M= -65, -90, -38, -27, -86, 36, -72, -78, -37, -83, 14, -69, 108, -68, -76, -64, -64, -81, -82, -83; D=-5; /I: I=-5; DM=-13; /M: SY='Y'; M= -53, 55, -73, -40, 40, -78, -51, -63, -13, -59, -58, -14, -83, -67, -66, -66, -6, -65, 54, 106; D=-5; /I: I=-5; DM=-13; /M: SY='D'; M= -34, -77, 57, 4, -79, 54, -43, -83, -18, -82, -76, -9, -69, -57, -56, 42, -49, -57, -82, 0; D=-5; /I: I=-5; MI=0; MD=-13; IM=0; DM=-13; /M: SY='Y'; M= -56, -83, -66, -72, -10, -2, 66, -70, -46, -66, -3, 41, -82, -62, -57, -65, -68, -74, 36, 99; D=-5; /I: I=-5; MI=0; MD=-13; IM=0; DM=-13; /M: SY='S'; M= -32, -73, 2, -22, -82, -67, -71, -77, -59, -81, -76, -54, -71, -62, -72, 68, 68, -69, -95, -76; D=-5; /I: I=-5; MI=0; MD=-13; IM=0; DM=-13; /M: SY='C'; M= -74, 82, -62, 51, -33, -49, -66, -86, 6, -81, -77, 17, -82, -62, -16, -70, -71, -82, -79, 46; D=-5; /I: I=-5; MI=0; MD=-13; IM=0; DM=-13; /M: SY='S'; M= -11, -71, -44, -62, -73, -61, -39, -69, 12, 8, -64, 48, -72, -30, -61, 70, -2, -67, -86, -70; D=-5; /I: I=-5; MI=0; MD=-13; IM=0; DM=-13; /M: SY='P'; M= 13, -77, 25, -56, -26, -70, 7, -38, 5, 26, -39, -63, 67, -25, 15, -30, -47, -26, -76, -7; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='P'; M= -1, 33, -40, -2, -34, -58, -68, -11, -27, -49, -36, -1, 68, -38, -42, 21, 27, 2, -8, -34; D=-26; /I: I=-26; DM=-67; /M: SY='P'; M= -26, -82, -11, 24, -74, -46, -66, -17, -7, 5, -47, -34, 87, -6, -45, 5, -59, -28, -80, -49; D=-26; /I: I=-26; DM=-67; /M: SY='D'; M= -36, -76, 71, 8, -82, -63, 12, -79, -52, -80, -72, 66, -24, 26, -10, -2, 22, -76, -93, -69; D=-26; /I: I=-26; DM=-67; /M: SY='D'; M= -13, -78, 62, 18, -9, -53, 44, -51, -4, 7, -61, -2, -33, 24, -25, -18, -41, -47, 5, -5; D=-26; /I: I=-26; DM=-67; /M: SY='E'; M= 25, -75, 24, 57, -77, -19, -21, -69, 1, -30, -8, -25, 0, 8, 5, -20, -11, -12, -82, -69; D=-26; /I: I=-26; DM=-67; /M: SY='E'; M= -9, -22, 3, 44, -11, -27, -63, 11, -57, -11, 17, 25, -69, -31, -8, -19, 22, 19, -81, -64; D=-26; /I: I=-26; DM=-67; /M: SY='F'; M= -68, -24, -76, -70, 66, -24, 28, -16, -66, 48, -23, -24, -81, 26, 6, -69, -65, -18, -62, 4; /M: SY='Q'; M= -26, -78, 18, 37, -60, -34, 20, -48, 20, -32, 2, 13, 2, 51, 32, 7, -41, -71, -79, -39; /M: SY='W'; M= -13, -76, 0, 48, -10, -72, 10, -40, -5, 16, -32, -29, -69, 27, -39, -4, 12, -41, 54, 29; /M: SY='L'; M= -47, -71, -82, -76, 38, -83, -9, 3, -74, 61, 30, -77, -81, -71, -45, -31, -44, 25, -65, 24; /M: SY='A'; M= 65, -70, -64, -6, -32, 17, -67, -28, -47, -30, -37, -25, 37, -59, -8, 15, -55, -52, -76, -46; /M: SY='K'; M= -46, -27, -9, 16, -45, -57, 19, 4, 54, -22, 2, -15, -69, 22, 29, 8, -30, -19, -75, -2; /M: SY='A'; M= 32, -72, -39, -27, -29, 22, -68, 9, 19, 10, -55, -25, -70, 8, -35, 9, -7, -7, 31, -63; /M: SY='Y'; M= 34, -71, -72, -70, 32, -43, -59, 1, -37, 22, 27, -1, -76, -64, -68, -4, -15, -22, -58, 65; /M: SY='A'; M= 66, 3, -11, -5, -73, -7, -69, -29, -30, -65, -61, -41, -46, -59, -67, 31, -12, 22, -81, -70; /I: I=-9; MD=-22; /M: SY='K'; M= -12, -78, 35, -24, -28, -23, -10, -63, 57, -46, -14, 17, -13, 31, -6, 10, -37, -55, -79, -28; D=-9; /I: I=-9; MD=-22; /M: SY='A'; M= 54, -71, 3, 10, -19, -19, -40, -47, -36, -30, -41, 24, -71, -23, -6, -8, -5, -2, -80, -27; D=-9; /I: I=-9; MD=-22; /M: SY='H'; M= -18, -12, -69, -45, -2, -76, 60, 36, -26, 32, 10, 26, -77, -6, -41, -22, -21, -15, -80, -56; D=-9; /I: I=-9; MD=-22; /M: SY='P'; M= 6, -80, -5, 2, 4, -8, 3, -50, 10, -49, -67, 9, 53, -22, 40, -19, -8, -72, -78, -40; D=-9; /I: I=-9; MD=-22; /M: SY='S'; M= 12, -76, 2, -43, -71, -68, 4, -8, 9, -1, 13, -13, -60, 23, -5, 38, 2, -40, 23, -50; D=-9; /I: I=-9; MD=-22; /M: SY='M'; M= -24, -78, -27, -76, 43, -83, -72, -12, -33, 0, 69, -44, -83, -72, 9, -28, 10, 12, -76, -30; D=-9; /I: I=-9; MD=-22; /M: SY='H'; M= -39, -85, -12, -47, -40, -75, 68, -34, -22, -76, -28, 3, -32, 22, -1, 26, 7, -77, -80, 43; D=-9; /I: I=-9; MD=-22; /M: SY='G'; M= -74, -93, 1, -7, -32, 41, 8, -89, -9, -21, -30, -50, -85, 1, 2, -50, -13, -87, -12, -79; D=-9; /I: I=-9; MD=-22; /M: SY='T'; M= -28, -91, -75, 5, -94, 6, -83, -46, -45, -72, -84, 2, -6, -27, -16, -26, 46, -67,-102, -90; D=-9; /I: I=-9; MI=0; MD=-22; IM=0; DM=-22; /M: SY='F'; M= -41, -58, -22, -8, 23, -67, -79, -40, 17, -73, -81, -26, -37, -14, 18, -2, -6, -69, -90, -40; D=-9; /I: I=-9; DM=-22; /M: SY='Y'; M= -38, -36, -65, -16, -10, -30, -7, -69, 6, -65, -75, -59, 17, -6, -35, -54, -46, -58, -69, 72; D=-9; /I: I=-9; DM=-22; /M: SY='T'; M= -74, 0, 2, -24, -67, 8, 16, -26, 14, -82, -27, 15, -47, -43, -5, -31, 19, -50, -90, 11; D=-9; /I: I=-9; DM=-22; /M: SY='G'; M= -39, -86, -36, -10, -39, 42, -4, -36, -58, -73, 31, -33, -82, -46, -62, -33, 6, -1, -80, 37; D=-9; /I: I=-9; DM=-22; /M: SY='G'; M= -46, -85, -63, -78, -44, 50, -75, 24, -33, -65, -68, -32, 19, -55, -46, 7, -27, -17, -77, 29; D=-9; /I: I=-9; DM=-22; /M: SY='P'; M= -12, -76, -16, -12, -73, -45, -36, -5, -54, -46, -25, 5, 47, 1, -57, 41, 38, -23, -83, -1; D=-9; /I: I=-9; DM=-22; /M: SY='C'; M= -18, 64, -27, -32, -74, -3, -66, 24, -21, -61, -64, 52, -41, 12, 7, 8, -18, -8, -88, -72; D=-9; /I: I=-9; DM=-22; /M: SY='G'; M= -1, 27, 13, -52, 4, 40, -69, -28, -21, -41, -69, -34, 13, -52, -49, 36, -1, -43, -78, -11; D=-9; /I: I=-9; DM=-22; /M: SY='F'; M= 27, -73, 15, -10, 34, -46, -27, -31, 3, -67, -65, 9, -26, -44, -31, 22, 16, -7, -76, -8; D=-9; /I: I=-9; DM=-22; /M: SY='T'; M= -7, -74, 7, -22, -45, -71, 4, -29, 7, -25, -61, -11, 5, -5, 17, 6, 51, 11, -83, -24; D=-9; /I: I=-9; DM=-22; /M: SY='W'; M= -44, -81, 32, -69, -57, -7, -77, 39, -36, 20, -5, -47, -38, -69, -28, -26, -66, 4, 104, -56; D=-9; /I: I=-9; DM=-22; /M: SY='Y'; M= -33, -82, -39, 11, -40, 10, 33, -36, -37, -36, -22, -34, -31, 20, -62, -47, -47, -44, -48, 102; D=-9; /I: I=-9; DM=-22; /M: SY='P'; M= -1, -77, -4, 17, -72, -52, -62, -13, 6, -16, -43, -4, 41, 35, -9, 30, -22, -7, -79, -18; D=-9; /I: I=-9; DM=-22; /M: SY='A'; M= 40, -23, -65, -16, -30, -42, -8, 7, -28, -22, -59, 0, -22, -60, -33, 40, 24, 11, -82, -66; D=-9; /I: I=-9; DM=-22; /M: SY='S'; M= 26, -73, -8, -36, -3, -17, -63, -69, 18, -17, -64, 9, 34, -29, -38, 45, -1, -66, -76, -2; D=-9; /I: I=-9; DM=-22; /M: SY='G'; M= -7, -78, -60, 18, -83, 87, -69, -47, -9, -83, -74, -3, -69, -62, -70, -52, -46, -79, -78, -78; D=-9; /I: I=-9; DM=-22; /M: SY='G'; M= -31, -71, -16, -65, -74, 66, 13, -48, -63, -21, -66, -21, -68, -60, -32, 53, 26, -52, -80, -69; /M: SY='M'; M= 17, -68, -22, -65, 25, -8, -62, -24, -64, -28, 71, -56, -69, -59, -67, 59, 30, -49, -72, -6; /M: SY='D'; M= 14, -4, 41, -39, -54, 16, -63, -1, -17, -9, -11, 5, -71, 37, 2, -11, -8, 6, -81, -66; /M: SY='D'; M= -66, -79, 98, -39, -81, -66, -54, -80, -8, -37, -74, 22, -51, -52, 38, -35, 0, -77, -94, -69; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='W'; M= -50, -28, -65, -78, 56, -76, -76, -39, -72, -28, 11, -13, -81, -73, -74, -74, -48, 5, 145, 37; /M: SY='A'; M= 45, 10, -67, -68, 34, -63, -65, 0, -65, -7, 45, 43, -73, -63, -69, 15, -26, 10, -74, -57; /M: SY='Y'; M= -36, -13, -74, -73, -16, -7, -21, -3, -18, -39, 11, -32, -80, -63, -29, -66, -65, -2, 84, 105; /M: SY='H'; M= -37, -77, 52, -15, -44, 16, 66, -36, 0, 4, -30, -4, -71, 0, 30, -20, -28, -37, -84, -60; /M: SY='Q'; M= -1, -75, 3, 8, -27, -69, 48, -8, -28, 8, -3, -13, -70, 53, -15, 13, -8, -20, 43, 2; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='G'; M= -17, -77, -2, -46, -21, 65, 47, -48, -25, -59, -68, -22, -71, -36, -13, -3, 20, -74, -1, 8; D=-36; /I: I=-36; DM=-90; /M: SY='I'; M= -1, -72, -39, -65, -35, -9, -8, 50, -2, -23, -51, 49, -73, 12, -38, -14, -16, 33, -81, -63; /M: SY='C'; M= -19, 95, -33, -39, -71, -73, -30, 10, 49, -18, -60, -50, 17, -8, 26, -15, -36, -48, -82, -69; /M: SY='Y'; M= -69, -25, -72, -44, 57, -78, 30, -24, -41, 6, 14, -1, 16, -66, -16, -67, -29, -5, 35, 78; /M: SY='S'; M= 34, 31, -55, 40, -76, -5, -63, -70, -58, -73, -68, -53, -38, -52, -64, 73, -27, -16, -82, -71; /M: SY='Y'; M= -26, -19, -79, -78, 73, -81, -56, 28, -73, 0, -20, -47, -83, -72, -71, -70, -64, -19, -43, 92; /M: SY='T'; M= -12, 28, -60, -59, -69, -68, -66, -61, -58, -22, -59, -30, -63, 36, -64, -4, 99, -54, -86, -66; /M: SY='F'; M= -21, 2, -82, -77, 58, -81, -70, 42, -75, 31, 40, -75, -24, -73, -75, -29, -19, 17, -63, 13; /M: SY='E'; M= -39, -81, -36, 102, -77, -42, -54, -83, 21, -76, -71, -57, -58, -37, -33, -57, -61, -76, -75, 7; /M: SY='L'; M= -31, 7, -78, -39, -25, -79, -68, -6, -73, 69, 49, -73, -78, -67, -73, -4, 14, -9, -75, -56; /M: SY='R'; M= -59, -78, -62, -57, -71, 6, -58, -77, -43, -76, -67, -11, 50, -51, 77, 40, 8, -73, -74, 16; /I: I=-11; MD=-29; /M: SY='C'; M= -39, 82, 71, -57, 35, 3, -66, -75, -69, -34, -71, -56, 19, -70, -75, -41, -33, -73, -80, 5; D=-11; /I: I=-11; MD=-29; /M: SY='C'; M= -68, 66, -52, -53, -28, -13, -72, -32, 27, -46, -30, 0, -79, -42, 11, -18, 45, -35, -87, -16; D=-11; /I: I=-11; MD=-29; /M: SY='G'; M= -60, -90, 0, -82, -96, 69, -83, -98, -80, -97, -44, -64, -83, -79, -55, 9, 8, -92, -94, -90; D=-11; /I: I=-11; MD=-29; /M: SY='S'; M= -37, 11, -35, -55, -36, -23, 2, -24, -19, -70, -13, 24, -86, -27, 9, 26, -4, -79, -90, 14; D=-11; /I: I=-11; MD=-29; /M: SY='Y'; M= -15, -94, -8, -42, -17, -46, 6, -52, -75, -66, -77, -16, -92, -75, 3, -5, -18, -82, -24, 72; D=-11; /I: I=-11; MI=0; MD=-29; IM=0; DM=-29; /M: SY='G'; M= -69, -93, 8, -30, -58, 67, -81, -65, -40, -97, -88, -23, 24, -46, -73, -39, -46, -94, -92, -89; D=-11; /I: I=-11; DM=-29; /M: SY='F'; M= -38, -82, -24, -69, 84, -83, -67, -67, 41, -61, -64, -45, -83, -8, 3, -71, -23, -69, -59, 25; D=-11; /I: I=-11; DM=-29; /M: SY='Y'; M= -50, -80, -81, -41, 38, -30, -8, -13, -6, 37, 3, -47, -85, -26, -28, -55, -35, -3, -15, 39; D=-11; /I: I=-11; DM=-29; /M: SY='P'; M= -50, -16, -27, -71, -66, -13, -39, -49, -52, 48, -54, -33, 72, -35, -34, -74, -69, -47, 16, -71; D=-11; /I: I=-11; DM=-29; /M: SY='P'; M= -53, -89, -45, -48, -66, -75, 33, -57, -13, -31, -70, -29, 95, -67, -22, -6, 3, -40, -87, -44; D=-11; /I: I=-11; DM=-29; /M: SY='P'; M= 27, -80, 14, 47, -84, -13, 20, -80, -11, -79, -70, -58, 49, 42, -2, -21, -49, -75, -82, -72; D=-11; /I: I=-11; DM=-29; /M: SY='E'; M= -17, -77, -3, 50, 8, -47, -60, -4, 1, -38, -24, -8, -68, 18, -19, 37, -21, -65, 26, 14; D=-11; /I: I=-11; DM=-29; /M: SY='Q'; M= -46, -12, -33, 22, -39, -27, 26, -70, -16, -38, -63, 34, -3, 69, -7, 0, 16, -22, -77, 12; D=-11; /I: I=-11; DM=-29; /M: SY='I'; M= -42, -76, -81, -48, 11, -50, -78, 78, -76, 30, -41, -74, -28, -41, -79, -21, 12, -22, -74, -57; D=-11; /I: I=-11; DM=-29; /M: SY='Q'; M= -22, -78, 10, 30, -50, -36, -64, 16, 18, -25, -23, -61, 31, 38, -14, -4, -58, 19, -78, -17; /M: SY='P'; M= -9, -82, 2, 6, -78, -45, -17, -62, -17, -35, -65, -44, 79, 35, 38, -17, -13, -45, -79, -19; /M: SY='T'; M= -22, -71, -38, 19, 19, -73, -63, -25, -58, 6, -55, -59, -69, -8, 4, 4, 68, -16, -71, 27; /M: SY='W'; M= 7, 62, -20, 17, -66, 32, -75, -26, -9, -70, -23, -63, -72, -63, -68, -14, 5, -14, 108, -60; /M: SY='E'; M= -16, -78, -35, 66, -47, -71, 6, -72, 23, -16, -64, -9, -65, 50, 5, 8, -17, -36, -80, -66; /M: SY='E'; M= -8, -77, 8, 73, -73, -47, -30, -15, 2, -15, 29, 10, -66, -12, -1, -26, -60, -22, -81, -42; /M: SY='N'; M= -23, -71, -35, -66, -42, 34, 9, -3, -61, -50, -11, 70, -71, -61, -52, -26, 53, -20, -81, 4; /M: SY='W'; M= -11, -78, -44, -45, 23, -48, -38, -20, 18, 12, 37, -36, -77, -17, 42, -25, -64, -31, 82, 34; /M: SY='E'; M= 36, -38, 30, 36, -21, -66, 15, -47, -7, 5, -11, 31, -70, -40, -5, -26, -58, -17, -82, -65; /M: SY='A'; M= 57, -26, -69, -66, 11, 20, -67, -61, -34, -49, 30, -61, -24, -62, -69, 34, -20, -1, -73, -4; /M: SY='C'; M= -3, 48, -83, -77, -15, -81, -75, 26, -76, 47, 41, -77, -80, -73, -77, -45, -32, 45, -79, -59; /M: SY='K'; M= -13, -74, -7, -30, -43, -18, -32, 18, 39, 35, 5, -11, -74, -6, -1, -38, -29, 8, -78, -62; /M: SY='T'; M= 23, -70, -61, -18, -12, -28, -24, -17, -5, -49, -35, 26, -70, 20, -51, 16, 45, 3, -73, 33; /M: SY='F'; M= -31, -73, -85, -80, 59, -44, -69, 40, -77, 39, 45, -78, -81, -75, -76, -73, -63, 13, -61, 30; /M: SY='M'; M= 15, -29, -79, -74, -18, 9, -71, 21, -40, 50, 52, -72, -77, -48, -73, -65, -9, -2, -1, -59; /M: SY='E'; M= -4, -78, 41, 54, -79, -57, -26, -62, 19, -59, -26, 18, -67, 27, 24, -4, -46, -31, 19, -68; /M: SY='H'; M= -10, -77, -37, 0, 43, -36, 67, -63, 12, -12, 38, -38, -73, 39, -38, -47, -19, -65, 4, 44; /M: SY='V'; M= 12, 40, -37, -58, -56, -76, -21, 3, -40, 23, -30, -30, -78, -49, -57, -21, 1, 59, -80, 0; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
Total number of hits | 167 in 157 different sequences |
Number of true positive hits | 167 in 157 different sequences |
Number of 'unknown' hits | 0 |
Number of false positive hits | 0 |
Number of false negative sequences | 0 |
Number of 'partial' sequences | 0 |
Precision (true positives / (true positives + false positives)) | 100.00 % |
Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria) |
Maximum number of repetitions [info] | 3 |
Matrix type [info] | protein_domain |
Scaling database [info] | reversed |
Author [info] | CJA_Sigrist |
Feature key [info] | DOMAIN |
Feature description [info] | Peptidase M14 |
Version [info] | 1 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
157 sequences
AEBP1_HUMAN (Q8IUX7), AEBP1_MOUSE (Q640N1), AEBP1_RAT (A2RUV9), BCN5_CLOPF (P08696), CBP1_SABMA (P86516), CBPA1_ANOGA (O02350), CBPA1_BOVIN (P00730), CBPA1_DROME (Q9VL86), CBPA1_DROPS (Q29NC4), CBPA1_HUMAN (P15085), CBPA1_MOUSE (Q7TPZ8), CBPA1_PIG (P09954), CBPA1_RAT (P00731), CBPA2_HUMAN (P48052), CBPA2_MOUSE (Q504N0), CBPA2_RAT (P19222), CBPA3_HUMAN (P15088), CBPA3_MOUSE (P15089), CBPA3_RAT (P21961), CBPA4_HUMAN (Q9UI42), CBPA4_MOUSE (Q6P8K8), CBPA5_HUMAN (Q8WXQ8), CBPA5_MACFA (Q4R7R2), CBPA5_MOUSE (Q8R4H4), CBPA6_HUMAN (Q8N4T0), CBPA6_MOUSE (Q5U901), CBPB1_AEDAE (A0A1S4F020), CBPB1_BOVIN (P00732), CBPB1_CANLF (P55261), CBPB1_HUMAN (P15086), CBPB1_PIG (P09955), CBPB1_RAT (P19223), CBPB2_BOVIN (Q2KIG3), CBPB2_HUMAN (Q96IY4), CBPB2_MOUSE (Q9JHH6), CBPB2_RAT (Q9EQV9), CBPB_ASTAS (P04069), CBPB_HELZE (Q3T905), CBPC1_CAEEL (O76373), CBPC1_CHICK (E1C3P4), CBPC1_DANRE (Q4U2V3), CBPC1_HUMAN (Q9UPW5), CBPC1_MOUSE (Q641K1), CBPC1_XENLA (Q6DD21), CBPC1_XENTR (A9JRL3), CBPC2_DANRE (A6H8T7), CBPC2_HUMAN (Q5U5Z8), CBPC2_MACFA (Q4R632), CBPC2_MOUSE (Q8CDK2), CBPC2_XENTR (Q0P4M4), CBPC3_BOVIN (E1B9D8), CBPC3_HUMAN (Q8NEM8), CBPC3_MOUSE (Q8CDP0), CBPC4_HUMAN (Q96MI9), CBPC4_MOUSE (Q09M05), CBPC5_AILME (D2GXM8), CBPC5_BOVIN (Q58CX9), CBPC5_DANRE (Q68EI3), CBPC5_HUMAN (Q8NDL9), CBPC5_MOUSE (Q09M02), CBPC5_RAT (B2GV17), CBPC5_XENTR (B0JZV4), CBPC6_CAEEL (Q09296), CBPC6_HUMAN (Q5VU57), CBPC6_MOUSE (Q09LZ8), CBPD_ANAPL (Q90240), CBPD_DROME (P42787), CBPD_HUMAN (O75976), CBPD_LOPSP (P83852), CBPD_MOUSE (O89001), CBPD_RAT(Q9JHW1), CBPE_BOVIN (P04836), CBPE_CAEEL (O17754), CBPE_HUMAN (P16870), CBPE_LOPAM (P37892), CBPE_MACFA (Q4R4M3), CBPE_MOUSE (Q00493), CBPE_PANTR (A5A6K7), CBPE_RAT(P15087), CBPM_HUMAN (P14384), CBPM_MOUSE (Q80V42), CBPM_PONAB (Q5RFD6), CBPN_BOVIN (Q2KJ83), CBPN_HUMAN (P15169), CBPN_MOUSE (Q9JJN5), CBPN_RAT(Q9EQV8), CBPO_BOVIN (Q0II73), CBPO_DANRE (B8JLQ9), CBPO_HUMAN (Q8IVL8), CBPS_STRGR (P18143), CBPS_STRMP (P39041), CBPT_THEVU (P29068), CBPZ1_PLAF7 (Q8I2A6), CBPZ_CHICK (Q8QGP3), CBPZ_HUMAN (Q66K79), CBPZ_MOUSE (Q8R4V4), CBPZ_RAT(O54858), CBPZ_SIMVI (P42788), CPXM1_HUMAN (Q96SM3), CPXM1_MOUSE (Q9Z100), CPXM2_HUMAN (Q8N436), CPXM2_MOUSE (Q9D2L5), ECM14_AJECG (C0NM08), ECM14_AJECH (C6H4F1), ECM14_AJECN (A6RCF5), ECM14_AJEDR (C5G6U8), ECM14_ARTBC (D4AKU7), ECM14_ARTGP (E4UPZ6), ECM14_ARTOC (C5FPR9), ECM14_ASPCL (A1CSU3), ECM14_ASPFC (B0XRS8), ECM14_ASPFN (B8NBP9), ECM14_ASPFU (Q4X1U0), ECM14_ASPNC (A2QZA2), ECM14_ASPOR (Q2TZK2), ECM14_ASPTN (Q0C9B4), ECM14_BLAGS (C5JZS0), ECM14_COCP7 (C5PHW9), ECM14_COCPS (E9DD69), ECM14_EMENI (Q5B011), ECM14_LEPMJ (E5A0U8), ECM14_NEOFI (A1DGH9), ECM14_PARBA (C1HE31), ECM14_PARBD (C1GDH9), ECM14_PARBP (C0SAI5), ECM14_PENRW (B6H233), ECM14_SCHPO (O74818), ECM14_SCLS1 (A7EUC0), ECM14_TALMQ (B6Q972), ECM14_TALSN (B8M2K0), ECM14_TRIVH (D4DIW7), ECM14_UNCRE (C4JEE1), ECM14_YEAST (P38836), ENP1_LYSSH (Q03415), MCPAL_ARTBC (D4B5N0), MCPAL_ARTOC (C5FH26), MCPAL_TRIVH (D4D675), MCPA_ARTBC (D4AS12), MCPA_ARTOC (C5FVN6), MCPA_TRIEQ (B8XGR3), MCPA_TRIRU (A6XGK3), MCPA_TRITO (B6V865), MCPA_TRIVH (D4DL57), MCPB_ARTBC (D4B1S6), MCPB_ARTOC (C5FYJ7), MCPB_TRIEQ (B8XGR2), MCPB_TRIRU (A6XHF7), MCPB_TRITO (B6V866), MCPB_TRIVH (D4D4Z1), MPAA_ECO57 (P0ACV7), MPAA_ECOLI (P0ACV6), MPAA_VIBC1 (A7N805), NNAD_DROME (Q9VY99), SOL1_ARATH (Q9M9H7), SURO1_CAEEL (Q9XU75), Y1242_ZYMMO (P30795), YQGT_BACSU (P54497)» more
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PDB [Detailed view] |
136 PDB
1ARL; 1ARM; 1AYE; 1BAV; 1CBX; 1CPB; 1CPS; 1CPX; 1DTD; 1EE3; 1ELL; 1ELM; 1F57; 1H8L; 1HDQ; 1HDU; 1HEE; 1IY7; 1KWM; 1M4L; 1NSA; 1OBR; 1PCA; 1PYT; 1QMU; 1UWY; 1YME; 1Z5R; 1ZG7; 1ZG8; 1ZG9; 1ZLH; 1ZLI; 2ABZ; 2BO9; 2BOA; 2C1C; 2CTB; 2CTC; 2JEW; 2NSM; 2PCU; 2PIY; 2PIZ; 2PJ0; 2PJ1; 2PJ2; 2PJ3; 2PJ4; 2PJ5; 2PJ6; 2PJ7; 2PJ8; 2PJ9; 2PJA; 2PJB; 2PJC; 2RFH; 2V77; 3CPA; 3D4U; 3D66; 3D67; 3D68; 3DGV; 3FJU; 3FVL; 3FX6; 3GLJ; 3I1U; 3KGQ; 3LMS; 3MN8; 3OSL; 3PRT; 3QNV; 3V38; 3V7Z; 3WAB; 3WC5; 3WC6; 3WC7; 4A94; 4AXV; 4BD9; 4CPA; 4DJL; 4DUK; 4F8Z; 4GM5; 4IAV; 4IHM; 4IK2; 4P10; 4UEE; 4UEZ; 4UIA; 4UIB; 4Z65; 5CPA; 5HVF; 5HVG; 5HVH; 5HXD; 5J1Q; 5JC6; 5LRG; 5LRJ; 5LRK; 5LYD; 5LYF; 5LYI; 5LYL; 5MRV; 5OM9; 5ZEQ; 6CPA; 6F6Q; 6F75; 6F79; 6GO2; 6I6Z; 6SN6; 6T9Y; 6TNK; 6Z28; 7AQP; 7ARU; 7CPA; 7EQX; 7EQZ; 7NEE; 7NEU; 7Q87; 8CPA; 8QVO » more |