To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Entry: PS60004

General information about the entry

Entry name [info] OMEGA_CONOTOXIN
Accession [info] PS60004
Entry type [info] PATTERN
Date [info] 01-OCT-2004 CREATED; 01-OCT-2004 DATA UPDATE; 27-SEP-2017 INFO UPDATE.
PROSITE Doc. [info] PDOC60004

Name and characterization of the entry

Description [info] Omega-conotoxin family signature.
Pattern [info]
C-[SREYKLIMQVN]-x(2)-[DGWET]-x-[FYSPKV]-C-[GNDSRHTP]-x(1,5)-[NPGSMTAHF]-
[GWPNIYRSKLQ]-x-C-C-[STRHGD]-x(0,2)-[NFLWSRYIT]-C-x(0,3)-[VFGAITSNRKL]-
[FLIKRNGH]-[VWIARKF]-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2017_09 which contains 555'594 sequence entries.


Total number of hits 66 in 66 different sequences
Number of true positive hits 58 in 58 different sequences
Number of 'unknown' hits 0
Number of false positive hits 8 in 8 different sequences
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 87.88 %
Recall (true positives / (true positives + false negatives)) 95.08 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 7
Site [info] disulfide at position 13
Site [info] disulfide at position 14
Site [info] disulfide at position 18
Site [info] disulfide at position 23
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
58 sequences

CM7E_CONCN  (P0DKQ3    ), CM7F_CONCN  (P0DKQ4    ), CM7G_CONCN  (P0DKQ5    ), 
CM7J_CONCN  (P0DKQ6    ), CO111_CONTE (Q9U648    ), CO112_CONST (Q5K0D6    ), 
CO115_CONST (Q5K0D5    ), CO12A_CONPL (Q9XYZ1    ), CO12_CONIM  (Q5K0B9    ), 
CO12_CONST  (Q5K0D8    ), CO12_CONTE  (Q9XZK9    ), CO13_CONIM  (Q5K0C0    ), 
CO13_CONST  (Q9XZK2    ), CO13_CONTE  (Q9XZL0    ), CO14_CONST  (Q9XZK3    ), 
CO14_CONTE  (Q9XZL1    ), CO15B_CONTE (Q9U654    ), CO15_CONST  (Q9XZK4    ), 
CO15_CONTE  (Q9XZL2    ), CO161_CONST (Q9XZL4    ), CO161_CONTE (Q3YEF3    ), 
CO162_CONST (Q9XZL5    ), CO164_CONAH (P0C8V8    ), CO164_CONVC (P69761    ), 
CO165_CONAH (P0C8V9    ), CO166_CONST (P0C831    ), CO167_CONMR (Q3YED6    ), 
CO16A_CONCT (P58917    ), CO16A_CONGE (P01522    ), CO16A_CONPL (Q9XYZ0    ), 
CO16A_CONST (P28880    ), CO16B_CONST (P28881    ), CO16D_CONCT (P58920    ), 
CO16_CONST  (Q5K0D3    ), CO16_CONTE  (Q9XZL3    ), CO17A_CONMA (P05484    ), 
CO194_CONTE (Q9U647    ), CO19_CONST  (Q5K0D2    ), CO1X1_CONTE (Q9XZK8    ), 
CO6A_CONPE  (P56712    ), CO6A_CONRA  (P58914    ), CO6A_CONTU  (P58915    ), 
CO6B_CONCT  (P58918    ), CO6B_CONPE  (P56713    ), CO6C_CONCT  (P58919    ), 
CO7AB_CONGE (P05483    ), CO7A_CONCN  (P58916    ), CO7B_CONMA  (P05485    ), 
CO7C_CONMA  (P37300    ), CO7D_CONMA  (Q26350    ), CO7_CONTE   (P56714    ), 
CO8_CONBU   (P0CY66    ), CU6B_CONPB  (P0DMA2    ), O1618_CONAE (Q9BP78    ), 
O162_CONAE  (Q9BH84    ), O163_CONAE  (Q9BP99    ), O164_CONTE  (Q9U645    ), 
O168_CONVE  (Q9BPA5    )
» more

UniProtKB/Swiss-Prot
False negative sequences
3 sequences

CO141_CONTE (Q9U651    ), CO142_CONTE (Q9U650    ), CO67_CONST  (P0C832    )

		
UniProtKB/Swiss-Prot
False positive sequences
8 sequences

CO163_CONAH (P0C8V7    ), CO16E_CONST (Q9XZK5    ), CO6A_CONCN  (P69750    ), 
CO6A_CONMA  (P69753    ), CO6A_CONSE  (P69757    ), CO6B_CONMA  (P69754    ), 
CO6C_CONMA  (P69755    ), CO6D_CONMA  (P69756    )
» more

PDB
[Detailed view]
12 PDB

1CNN; 1DW4; 1DW5; 1F3K; 1FEO; 1FYG; 1MVI; 1MVJ; 1OMG; 1OMN; 1TT3; 1TTK

View entry in original PROSITE format
View entry in raw text format (no links)
Direct ScanProsite submission