Entry: PS60014

General information about the entry

Entry name [info] ALPHA_CONOTOXIN
Accession [info] PS60014
Entry type [info] PATTERN
Date [info] MAR-2005 (CREATED); OCT-2005 (DATA UPDATE); MAY-2016 (INFO UPDATE).
PROSITE Doc. [info] PDOC60004

Name and characterization of the entry

Description [info] Alpha-conotoxin family signature.
Pattern [info]
C-C-[SHYN]-x(0,1)-[PRG]-[RPATV]-C-[ARMFTNHG]-x(0,4)-[QWHDGENLFYVP]-
[RIVYLGSDW]-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2016_05 which contains 551'193 sequence entries.


Total number of hits 56 in 56 different sequences
Number of true positive hits 52 in 52 different sequences
Number of 'unknown' hits 1
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 45
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 94.55 %
Recall (true positives / (true positives + false negatives)) 53.61 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 2
Site [info] disulfide at position 7
Site [info] disulfide at position 12
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
52 sequences

CA11B_CONAH (P0CAQ5    ), CA11_CONAJ  (P0CB07    ), CA11_CONCT  (D4HPD6    ), 
CA11_CONSE  (P0C8V1    ), CA12_CONAJ  (P0CB08    ), CA12_CONVC  (E2DIH5    ), 
CA13_CONBN  (P0C1Y2    ), CA13_CONMR  (A0SE59    ), CA14_CONMN  (P0C8U5    ), 
CA16_CONQU  (A1X8D1    ), CA1AB_CONSP (P85886    ), CA1A_CONAL  (P56639    ), 
CA1A_CONBU  (P69657    ), CA1A_CONCN  (P56973    ), CA1A_CONGE  (P01519    ), 
CA1A_CONLG  (X1WB75    ), CA1A_CONOM  (P0C1R7    ), CA1A_CONPE  (P50984    ), 
CA1A_CONPU  (P69658    ), CA1A_CONST  (P28878    ), CA1A_CONVC  (P69747    ), 
CA1B_CONAL  (P56640    ), CA1B_CONAN  (P0C1V7    ), CA1B_CONPE  (P50985    ), 
CA1C_CONAL  (P56641    ), CA1C_CONAN  (P0C1V8    ), CA1C_CONCN  (P0C8U4    ), 
CA1C_CONGE  (Q86RB2    ), CA1D_CONGE  (P60274    ), CA1L_CONCN  (P0DKP6    ), 
CA1_CONEP   (P56638    ), CA1_CONER   (P50982    ), CA1_CONIM   (P50983    ), 
CA1_CONMA   (P01521    ), CA2A_CONIM  (Q9U619    ), CA2A_CONRE  (P85013    ), 
CA2_CONGE   (P01520    ), CA2_CONIM   (Q8I6R5    ), CA2_CONMA   (P56636    ), 
CA2_CONTE   (Q9XZK7    ), CA89_CONAJ  (P0CB12    ), CA91_CONAJ  (P0CB13    ), 
CAI2_CONPE  (Q9BP56    ), CAIA_CONAE  (P0C8R2    ), CAIA_CONLI  (L8BU87    ), 
CAIB_CONTE  (K4RNX9    ), CAS1_CONST  (P15471    ), CAS2_CONST  (P28879    ), 
CAX1_CONTE  (Q9XZK6    ), CO16A_CONVX (Q86RA3    ), CXA1A_CONRE (P0C1D0    ), 
CXA1E_CONRE (P85011    )
» more

UniProtKB/Swiss-Prot
False negative sequences
45 sequences

CA11A_CONAH (P0CAQ4    ), CA11A_CONQU (Q6PTD7    ), CA11B_CONQU (Q6PPB3    ), 
CA11C_CONQU (A1X8C6    ), CA11_CONBN  (P0CE73    ), CA11_CONCB  (P0C1V9    ), 
CA11_CONLE  (Q6PTD5    ), CA11_CONLT  (Q2I2R8    ), CA11_CONMR  (Q6PTD1    ), 
CA11_CONPL  (A0SE60    ), CA11_CONST  (P0C1W4    ), CA12_CONBN  (P0CE74    ), 
CA12_CONCB  (P0C1W0    ), CA12_CONLE  (Q6PTD4    ), CA12_CONLT  (Q2I2R7    ), 
CA12_CONMR  (A6M934    ), CA12_CONPL  (A1X8D8    ), CA13_CONLT  (Q2I2R6    ), 
CA141_CONPL (C6ZJQ2    ), CA14A_CONQU (P0CAQ8    ), CA14A_CONTS (P86362    ), 
CA14B_CONQU (P0CAQ9    ), CA14_CONBR  (P0C8U3    ), CA14_CONLE  (A1X8B6    ), 
CA14_CONPL  (P0C8U8    ), CA15_CONPL  (P0C8U9    ), CA15_CONQU  (A1X8D0    ), 
CA16A_CONLE (P0CAQ6    ), CA16B_CONLE (P0CAQ7    ), CA16_CONPL  (P0C8V0    ), 
CA17_CONLE  (A1X8C3    ), CA18_CONLE  (A1X8C2    ), CA1A_CONLE  (A6M938    ), 
CA1A_CONMA  (P0C1W1    ), CA1A_CONPR  (Q1L777    ), CA1A_CONTI  (P0CI05    ), 
CA1B_CONPU  (P0C351    ), CA1B_CONRE  (P85009    ), CA1D_CONRE  (P85010    ), 
CA1F_CONRE  (P85012    ), CA1_CONQU   (A1X8B8    ), CA1_CONTE   (P86261    ), 
CA2_CONQU   (A1X8B9    ), CXA12_CONQU (Q6PTD6    ), CXA1B_CONRE (C0HJA8    )
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

CM34_CONMR  (P0C1N3    )

		
UniProtKB/Swiss-Prot
False positive sequences
3 sequences

CM65_CONCL  (D6C4L2    ), SJ380_SCHJA (Q5DBT1    ), SJ643_SCHJA (Q5DFA1    )

		
PDB
[Detailed view]
40 PDB

1A0M; 1AKG; 1B45; 1CNL; 1DG2; 1E76; 1G2G; 1HJE; 1IM1; 1IMI; 1K64; 1M2C; 1MII; 1MTQ; 1MXN; 1MXP; 1NOT; 1PEN; 1QMW; 1UL2; 1XGA; 1XGB; 1XGC; 1ZLC; 2AJW; 2AK0; 2C9T; 2GCZ; 2H8S; 2I28; 2IGU; 2JUR; 2JUS; 2JUT; 2LZ5; 2MD6; 2MDQ; 2NS3; 4EZ1; 4TTL
» more

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