Entry: PS60014

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General information about the entry

Entry name [info] ALPHA_CONOTOXIN
Accession [info] PS60014
Entry type [info] PATTERN
Date [info] MAR-2005 (CREATED); OCT-2005 (DATA UPDATE); JUN-2014 (INFO UPDATE).
PROSITE Doc. [info] PDOC60004

Name and characterization of the entry

Description [info] Alpha-conotoxin family signature.
Pattern [info]
C-C-[SHYN]-x(0,1)-[PRG]-[RPATV]-C-[ARMFTNHG]-x(0,4)-[QWHDGENLFYVP]-
[RIVYLGSDW]-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2014_07 which contains 546'000 sequence entries.


Total number of hits 54 in 54 different sequences
Number of true positive hits 50 in 50 different sequences
Number of 'unknown' hits 1
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 45
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 94.34 %
Recall (true positives / (true positives + false negatives)) 52.63 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 2
Site [info] disulfide at position 7
Site [info] disulfide at position 12
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
50 sequences

CA11B_CONAH (P0CAQ5), CA11_CONAJ  (P0CB07), CA11_CONCT  (D4HPD6), 
CA11_CONSE  (P0C8V1), CA12_CONAJ  (P0CB08), CA12_CONVC  (E2DIH5), 
CA13_CONBN  (P0C1Y2), CA13_CONMR  (A0SE59), CA14_CONMN  (P0C8U5), 
CA16_CONQU  (A1X8D1), CA1AB_CONSP (P85886), CA1A_CONAL  (P56639), 
CA1A_CONBU  (P69657), CA1A_CONCN  (P56973), CA1A_CONGE  (P01519), 
CA1A_CONOM  (P0C1R7), CA1A_CONPE  (P50984), CA1A_CONPU  (P69658), 
CA1A_CONST  (P28878), CA1A_CONVC  (P69747), CA1B_CONAL  (P56640), 
CA1B_CONAN  (P0C1V7), CA1B_CONPE  (P50985), CA1C_CONAL  (P56641), 
CA1C_CONAN  (P0C1V8), CA1C_CONCN  (P0C8U4), CA1C_CONGE  (Q86RB2), 
CA1D_CONGE  (P60274), CA1L_CONCN  (P0DKP6), CA1_CONEP   (P56638), 
CA1_CONER   (P50982), CA1_CONIM   (P50983), CA1_CONMA   (P01521), 
CA2A_CONIM  (Q9U619), CA2A_CONRE  (P85013), CA2_CONGE   (P01520), 
CA2_CONIM   (Q8I6R5), CA2_CONMA   (P56636), CA2_CONTE   (Q9XZK7), 
CA89_CONAJ  (P0CB12), CA91_CONAJ  (P0CB13), CAI2_CONPE  (Q9BP56), 
CAIA_CONAE  (P0C8R2), CAIB_CONTE  (K4RNX9), CAS1_CONST  (P15471), 
CAS2_CONST  (P28879), CAX1_CONTE  (Q9XZK6), CO16A_CONVX (Q86RA3), 
CXA1A_CONRE (P0C1D0), CXA1E_CONRE (P85011)
» More

UniProtKB/Swiss-Prot
False negative sequences
45 sequences

CA11A_CONAH (P0CAQ4), CA11A_CONQU (Q6PTD7), CA11B_CONQU (Q6PPB3), 
CA11C_CONQU (A1X8C6), CA11_CONBN  (P0CE73), CA11_CONCB  (P0C1V9), 
CA11_CONLE  (Q6PTD5), CA11_CONLT  (Q2I2R8), CA11_CONMR  (Q6PTD1), 
CA11_CONPL  (A0SE60), CA11_CONST  (P0C1W4), CA12_CONBN  (P0CE74), 
CA12_CONCB  (P0C1W0), CA12_CONLE  (Q6PTD4), CA12_CONLT  (Q2I2R7), 
CA12_CONMR  (A6M934), CA12_CONPL  (A1X8D8), CA13_CONLT  (Q2I2R6), 
CA141_CONPL (C6ZJQ2), CA14A_CONQU (P0CAQ8), CA14A_CONTS (P86362), 
CA14B_CONQU (P0CAQ9), CA14_CONBR  (P0C8U3), CA14_CONLE  (A1X8B6), 
CA14_CONPL  (P0C8U8), CA15_CONPL  (P0C8U9), CA15_CONQU  (A1X8D0), 
CA16A_CONLE (P0CAQ6), CA16B_CONLE (P0CAQ7), CA16_CONPL  (P0C8V0), 
CA17_CONLE  (A1X8C3), CA18_CONLE  (A1X8C2), CA1A_CONLE  (A6M938), 
CA1A_CONMA  (P0C1W1), CA1A_CONPR  (Q1L777), CA1A_CONTI  (P0CI05), 
CA1B_CONPU  (P0C351), CA1B_CONRE  (P85009), CA1D_CONRE  (P85010), 
CA1F_CONRE  (P85012), CA1_CONQU   (A1X8B8), CA1_CONTE   (P86261), 
CA2_CONQU   (A1X8B9), CXA12_CONQU (Q6PTD6), CXA1B_CONRE (C0HJA8)
» More

UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

CM34_CONMR  (P0C1N3)

		
UniProtKB/Swiss-Prot
False positive sequences
3 sequences

CM65_CONCL  (D6C4L2), SJ380_SCHJA (Q5DBT1), SJ643_SCHJA (Q5DFA1)

		
PDB
[Detailed view]
37 PDB

1A0M; 1AKG; 1B45; 1CNL; 1DG2; 1E76; 1G2G; 1HJE; 1IM1; 1IMI; 1K64; 1M2C; 1MII; 1MTQ; 1MXN; 1MXP; 1NOT; 1PEN; 1QMW; 1UL2; 1XGA; 1XGB; 1XGC; 1ZLC; 2AJW; 2AK0; 2C9T; 2GCZ; 2H8S; 2I28; 2IGU; 2JUR; 2JUS; 2JUT; 2LZ5; 2NS3; 4EZ1
» More

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