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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
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Amos Bairoch

PROSITE entry PS00750


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PURL: https://purl.expasy.org/prosite/signature/PS00750

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General information about the entry

Entry name [info] TCP1_1
Accession [info] PS00750
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00610

Name and characterization of the entry

Description [info] Chaperonins TCP-1 signature 1.
Pattern [info] 
[RKEL]-[ST]-x-[LMFY]-G-P-x-[GSA]-x-x-K-[LIVMF](2).

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 149 in 149 different sequences
Number of true positive hits 148 in 148 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 5
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 99.33 %
Recall (true positives / (true positives + false negatives)) 96.73 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 148 sequences 

TCPA_ARATH  (P28769), TCPA_BOVIN  (Q32L40), TCPA_CAEEL  (P41988), 

TCPA_CRIGR  (P18279), TCPA_DICDI  (Q55BM4), TCPA_DROME  (P12613), 
TCPA_HUMAN  (P17987), TCPA_MACFA  (Q4R5G2), TCPA_MONDO  (Q9XT06), 
TCPA_MOUSE  (P11983), TCPA_PALPA  (Q9W790), TCPA_RAT(P28480), 
TCPA_SCHMA  (Q94757), TCPA_SCHPO  (O94501), TCPA_TETPY  (O15891), 
TCPA_YEAST  (P12612), TCPB_ARATH  (Q940P8), TCPB_BOVIN  (Q3ZBH0), 
TCPB_CAEEL  (P47207), TCPB_DICDI  (Q54ES9), TCPB_ENCCU  (Q8SQP2), 
TCPB_HUMAN  (P78371), TCPB_MACFA  (Q4R6F8), TCPB_MOUSE  (P80314), 
TCPB_RAT(Q5XIM9), TCPB_SCHPO  (Q10147), TCPB_YEAST  (P39076), 
TCPD_ARATH  (Q9LV21), TCPD_BOVIN  (Q2T9X2), TCPD_CAEEL  (P47208), 
TCPD_CANGA  (Q6FQT2), TCPD_DEBHA  (Q6BXF6), TCPD_DICDI  (Q54CL2), 
TCPD_EREGS  (Q75A36), TCPD_HUMAN  (P50991), TCPD_KLULA  (Q6CL82), 
TCPD_MOUSE  (P80315), TCPD_OCHTR  (Q9NB32), TCPD_PONAB  (Q5R637), 
TCPD_RAT(Q7TPB1), TCPD_SCHPO  (P50999), TCPD_TAKRU  (P53451), 
TCPD_YARLI  (Q6C100), TCPD_YEAST  (P39078), TCPE1_AVESA (P40412), 
TCPE2_AVESA (P54411), TCPE_ARATH  (O04450), TCPE_CAEEL  (P47209), 
TCPE_DICDI  (Q54TD3), TCPE_HUMAN  (P48643), TCPE_MACFA  (Q4R6V2), 
TCPE_MOUSE  (P80316), TCPE_PONAB  (Q5RF02), TCPE_RAT(Q68FQ0), 
TCPE_SCHPO  (Q9UTM4), TCPE_YEAST  (P40413), TCPG_ARATH  (Q84WV1), 
TCPG_BOVIN  (Q3T0K2), TCPG_CAEEL  (Q9N4J8), TCPG_DICDI  (Q54TH8), 
TCPG_DROME  (P48605), TCPG_ENCCU  (Q8SR76), TCPG_HUMAN  (P49368), 
TCPG_MACFA  (Q4R963), TCPG_MOUSE  (P80318), TCPG_OXYGR  (O00782), 
TCPG_PIG(Q29068), TCPG_PONAB  (Q5NVF9), TCPG_RAT(Q6P502), 
TCPG_SCHPO  (O74341), TCPG_THAWE  (Q9LKI7), TCPG_XENLA  (P50143), 
TCPG_YEAST  (P39077), TCPH_ARATH  (Q9SF16), TCPH_BOVIN  (Q2NKZ1), 
TCPH_CHICK  (Q5ZJK8), TCPH_DICDI  (Q54ER7), TCPH_ENCCU  (Q8SR53), 
TCPH_HUMAN  (Q99832), TCPH_MOUSE  (P80313), TCPH_PLAF7  (O77323), 
TCPH_PONAB  (Q5R5C8), TCPH_SCHPO  (P87153), TCPH_TETPY  (P54409), 
TCPQ_ARATH  (Q94K05), TCPQ_BOVIN  (Q3ZCI9), TCPQ_CAEBR  (A8X6I9), 
TCPQ_CAEEL  (Q9N358), TCPQ_CANAX  (P47828), TCPQ_CHICK  (Q6EE31), 
TCPQ_DICDI  (Q552J0), TCPQ_HUMAN  (P50990), TCPQ_MACFA  (Q4R5J0), 
TCPQ_MOUSE  (P42932), TCPQ_PONAB  (Q5RAP1), TCPQ_SCHPO  (P78921), 
TCPQ_YEAST  (P47079), TCPW_BOVIN  (Q3T084), TCPW_HUMAN  (Q92526), 
TCPZA_ARATH (Q9M888), TCPZB_ARATH (Q8L7N0), TCPZ_BOVIN  (Q3MHL7), 
TCPZ_CAEEL  (P46550), TCPZ_CHICK  (Q5ZJ54), TCPZ_DICDI  (Q76NU3), 
TCPZ_HUMAN  (P40227), TCPZ_MOUSE  (P80317), TCPZ_PIG(Q29236), 
TCPZ_PONAB  (Q5RCD2), TCPZ_RABIT  (O77622), TCPZ_SCHPO  (O94515), 
TCPZ_YEAST  (P39079), THS1_HALVD  (O30561), THS2_HALVD  (O30560), 
THS3_HALVD  (Q9HHA2), THSA_AERPE  (Q9YDK6), THSA_ARCFU  (O28045), 
THSA_HALSA  (Q9HN70), THSA_METTH  (O26320), THSA_SACS2  (Q9V2S9), 
THSA_SACSH  (P46219), THSA_SULAC  (Q9V2T5), THSA_SULTO  (O24734), 
THSA_THEAC  (P48424), THSA_THEK1  (P61112), THSA_THEK8  (O24731), 
THSA_THEKO  (P61111), THSB_AERPE  (Q9YA66), THSB_ARCFU  (O28821), 
THSB_DESMO  (Q9V2T3), THSB_HALSA  (Q9HNI0), THSB_METTH  (O26885), 
THSB_SACS2  (Q9V2T8), THSB_SACSH  (P28488), THSB_SULAC  (Q9V2T4), 
THSB_SULTO  (O24735), THSB_THEAC  (P48425), THSB_THEK1  (O24730), 
THSB_THEK8  (O24732), THSB_THEKO  (Q52500), THSG_SACS2  (Q9V2T7), 
THSG_SACSH  (Q9HH21), THS_DESSY   (Q53546), THS_METJA   (Q58405), 
THS_METKA   (P50016), THS_METTL   (O93624), THS_PYRAB   (Q9V2Q7), 
THS_PYRHO   (O57762)
» more

UniProtKB/Swiss-Prot
False negative sequences		 5 sequences 

TCPG_TETPY  (P54408), TCPH_YEAST  (P42943), TCPQL_HUMAN (A6NM43), 

TCPQM_HUMAN (Q96SF2), TCPW_MOUSE  (Q61390)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 4 sequences 

TCPA_AMBME  (P50157), TCPA_MESAU  (P86208), TCPB_MESAU  (P86245), 

TCPH_TETTH  (P54410)
» more

UniProtKB/Swiss-Prot
False positive sequences		 1 sequence 

RDC1_METCM  (B3FWT6)


				
	

	

		PDB
[Detailed view]		
		
			93 PDB
			


			pdb_00001a6d; pdb_00001a6e; pdb_00001q2v; pdb_00001q3q; pdb_00001q3r; pdb_00001q3s; pdb_00003iyg; pdb_00003ktt; pdb_00004a0o; pdb_00004a0v; pdb_00004a0w; pdb_00004a13; 
			
				pdb_00004b2t; pdb_00004v81; pdb_00004v8r; pdb_00004v94; pdb_00004xcd; pdb_00004xcg; pdb_00004xci; pdb_00005gw4; pdb_00005gw5; pdb_00005uyx; pdb_00005uyz; pdb_00006krd; 
				pdb_00006kre; pdb_00006ks6; pdb_00006ks7; pdb_00006ks8; pdb_00006nr8; pdb_00006nr9; pdb_00006nra; pdb_00006nrb; pdb_00006nrc; pdb_00006nrd; pdb_00006qb8; pdb_00006xhi; 
				pdb_00006xhj; pdb_00007lum; pdb_00007lup; pdb_00007nvl; pdb_00007nvm; pdb_00007nvn; pdb_00007nvo; pdb_00007trg; pdb_00007ttn; pdb_00007ttt; pdb_00007tub; pdb_00007wu7; 
				pdb_00007wz3; pdb_00007x0a; pdb_00007x0s; pdb_00007x0v; pdb_00007x3j; pdb_00007x3u; pdb_00007x6q; pdb_00007x7y; pdb_00007ylu; pdb_00007ylv; pdb_00007ylw; pdb_00007ylx; 
				pdb_00007yly; pdb_00008ajm; pdb_00008ajo; pdb_00008hki; pdb_00008i1u; pdb_00008i6j; pdb_00008i9q; pdb_00008i9u; pdb_00008ib8; pdb_00008sfe; pdb_00008sff; pdb_00008sg8; 
				pdb_00008sg9; pdb_00008sgc; pdb_00008sgl; pdb_00008sgq; pdb_00008sh9; pdb_00008sha; pdb_00008shd; pdb_00008she; pdb_00008shf; pdb_00008shg; pdb_00008shl; pdb_00008shn; 
				pdb_00008sho; pdb_00008shp; pdb_00008shq; pdb_00008sht; pdb_00009cr2; pdb_00009cs3; pdb_00009cs4; pdb_00009cs6; pdb_00009csa
			
			

			» more