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PROSITE entry PS00865


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PURL: https://purl.expasy.org/prosite/signature/PS00865

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General information about the entry

Entry name [info] UBIQUITIN_ACTIVAT_2
Accession [info] PS00865
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00463
Associated ProRule [info] PRU10132

Name and characterization of the entry

Description [info] Ubiquitin-activating enzyme active site.
Pattern [info] 
P-[LIVMG]-C-T-[LIVM]-[KRHA]-x-[FTNM]-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 36 in 36 different sequences
Number of true positive hits 36 in 36 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 92.31 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 36 sequences 

SAE2A_XENLA (Q642Q1), SAE2B_XENLA (Q7ZY60), SAE2_CAEEL  (Q9NAN1), 

SAE2_DANRE  (Q7SXG4), SAE2_HUMAN  (Q9UBT2), SAE2_MOUSE  (Q9Z1F9), 
SAE2_XENTR  (Q28GH3), UBA1Y_MOUSE (P31254), UBA1_BOVIN  (A3KMV5), 
UBA1_CANAW  (P52495), UBA1_DICDI  (Q55C16), UBA1_HUMAN  (P22314), 
UBA1_MOUSE  (Q02053), UBA1_RABIT  (Q29504), UBA1_RAT(Q5U300), 
UBA1_SCHPO  (O94609), UBA1_YEAST  (P22515), UBA2_SCHPO  (O42939), 
UBA2_YEAST  (P52488), UBA3_ARATH  (O65041), UBA3_CAEEL  (Q19360), 
UBA3_DANRE  (Q7ZVX6), UBA3_DROME  (Q9V6U8), UBA3_HUMAN  (Q8TBC4), 
UBA3_MOUSE  (Q8C878), UBA3_PONAB  (Q5R4A0), UBA3_RAT(Q99MI7), 
UBA3_SCHPO  (Q09765), UBA3_YEAST  (Q99344), UBA7_HUMAN  (P41226), 
UBE11_ARATH (P93028), UBE11_WHEAT (P20973), UBE12_ARATH (P92974), 
UBE12_WHEAT (P31251), UBE13_WHEAT (P31252), UBE1Y_OSPRU (P31255)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

UBA3_DICDI  (Q54QG9), UBA6_HUMAN  (A0AVT1), UBA6_MOUSE  (Q8C7R4)


				
	

	

		PDB
[Detailed view]		
		
			58 PDB
			


			pdb_00001tt5; pdb_00001yov; pdb_00001z7l; pdb_00002nvu; pdb_00002px9; pdb_00003cmm; pdb_00003gzn; pdb_00003kyc; pdb_00003kyd; pdb_00004ii2; pdb_00004ii3; pdb_00004nnj; 
			
				pdb_00005knl; pdb_00005l6h; pdb_00005l6i; pdb_00005l6j; pdb_00005tr4; pdb_00006cwy; pdb_00006cwz; pdb_00006nya; pdb_00006o82; pdb_00006o83; pdb_00006xog; pdb_00006xoh; 
				pdb_00006xoi; pdb_00006zhs; pdb_00006zht; pdb_00006zhu; pdb_00006zqh; pdb_00007k5j; pdb_00007zh9; pdb_00008oif; pdb_00008se9; pdb_00008sea; pdb_00008seb; pdb_00008sv8; 
				pdb_00009b5c; pdb_00009b5d; pdb_00009b5e; pdb_00009b5f; pdb_00009b5g; pdb_00009b5h; pdb_00009b5i; pdb_00009b5j; pdb_00009b5k; pdb_00009b5l; pdb_00009b5m; pdb_00009b5n; 
				pdb_00009b5o; pdb_00009b5p; pdb_00009b5q; pdb_00009b5r; pdb_00009b5s; pdb_00009b5t; pdb_00009b5u; pdb_00009b5v; pdb_00009b5w; pdb_00009b5x
			
			

			» more