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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00995


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PURL: https://purl.expasy.org/prosite/signature/PS00995

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General information about the entry

Entry name [info] TCP1_3
Accession [info] PS00995
Entry type [info] PATTERN
Date [info] 01-JUN-1994 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00610

Name and characterization of the entry

Description [info] Chaperonins TCP-1 signature 3.
Pattern [info] 
Q-[DEK]-x-x-[LIVMGTA]-[GA]-D-G-T.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 155 in 155 different sequences
Number of true positive hits 143 in 143 different sequences
Number of 'unknown' hits 0
Number of false positive hits 12 in 12 different sequences
Number of false negative sequences 9
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 92.26 %
Recall (true positives / (true positives + false negatives)) 94.08 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 143 sequences 

TCPA_ARATH  (P28769), TCPA_BOVIN  (Q32L40), TCPA_CAEEL  (P41988), 

TCPA_CRIGR  (P18279), TCPA_DICDI  (Q55BM4), TCPA_DROME  (P12613), 
TCPA_ENCCU  (Q8SSC9), TCPA_HUMAN  (P17987), TCPA_MACFA  (Q4R5G2), 
TCPA_MONDO  (Q9XT06), TCPA_MOUSE  (P11983), TCPA_PALPA  (Q9W790), 
TCPA_RAT(P28480), TCPA_SCHMA  (Q94757), TCPA_SCHPO  (O94501), 
TCPA_TETPY  (O15891), TCPA_YEAST  (P12612), TCPB_ARATH  (Q940P8), 
TCPB_BOVIN  (Q3ZBH0), TCPB_CAEEL  (P47207), TCPB_DICDI  (Q54ES9), 
TCPB_HUMAN  (P78371), TCPB_MACFA  (Q4R6F8), TCPB_MESAU  (P86245), 
TCPB_MOUSE  (P80314), TCPB_RAT(Q5XIM9), TCPB_SCHPO  (Q10147), 
TCPB_YEAST  (P39076), TCPD_ARATH  (Q9LV21), TCPD_BOVIN  (Q2T9X2), 
TCPD_CAEEL  (P47208), TCPD_CANGA  (Q6FQT2), TCPD_DEBHA  (Q6BXF6), 
TCPD_DICDI  (Q54CL2), TCPD_EREGS  (Q75A36), TCPD_HUMAN  (P50991), 
TCPD_KLULA  (Q6CL82), TCPD_MOUSE  (P80315), TCPD_OCHTR  (Q9NB32), 
TCPD_PONAB  (Q5R637), TCPD_RAT(Q7TPB1), TCPD_SCHPO  (P50999), 
TCPD_TAKRU  (P53451), TCPD_YARLI  (Q6C100), TCPD_YEAST  (P39078), 
TCPE1_AVESA (P40412), TCPE2_AVESA (P54411), TCPE_ARATH  (O04450), 
TCPE_CAEEL  (P47209), TCPE_DICDI  (Q54TD3), TCPE_ENCCU  (Q8SRP9), 
TCPE_HUMAN  (P48643), TCPE_MACFA  (Q4R6V2), TCPE_MOUSE  (P80316), 
TCPE_PONAB  (Q5RF02), TCPE_RAT(Q68FQ0), TCPE_SCHPO  (Q9UTM4), 
TCPE_YEAST  (P40413), TCPG_ARATH  (Q84WV1), TCPG_BOVIN  (Q3T0K2), 
TCPG_CAEEL  (Q9N4J8), TCPG_DICDI  (Q54TH8), TCPG_DROME  (P48605), 
TCPG_ENCCU  (Q8SR76), TCPG_HUMAN  (P49368), TCPG_MOUSE  (P80318), 
TCPG_OXYGR  (O00782), TCPG_PIG(Q29068), TCPG_PONAB  (Q5NVF9), 
TCPG_RAT(Q6P502), TCPG_SCHPO  (O74341), TCPG_TETPY  (P54408), 
TCPG_XENLA  (P50143), TCPG_YEAST  (P39077), TCPH_ARATH  (Q9SF16), 
TCPH_BOVIN  (Q2NKZ1), TCPH_CHICK  (Q5ZJK8), TCPH_DICDI  (Q54ER7), 
TCPH_ENCCU  (Q8SR53), TCPH_HUMAN  (Q99832), TCPH_MOUSE  (P80313), 
TCPH_PLAF7  (O77323), TCPH_PONAB  (Q5R5C8), TCPH_SCHPO  (P87153), 
TCPH_TETPY  (P54409), TCPH_TETTH  (P54410), TCPH_YEAST  (P42943), 
TCPQ_BOVIN  (Q3ZCI9), TCPQ_CHICK  (Q6EE31), TCPQ_DICDI  (Q552J0), 
TCPQ_HUMAN  (P50990), TCPQ_MACFA  (Q4R5J0), TCPQ_MOUSE  (P42932), 
TCPQ_PONAB  (Q5RAP1), TCPQ_YEAST  (P47079), TCPW_BOVIN  (Q3T084), 
TCPW_HUMAN  (Q92526), TCPW_MOUSE  (Q61390), TCPZ_BOVIN  (Q3MHL7), 
TCPZ_CAEEL  (P46550), TCPZ_CHICK  (Q5ZJ54), TCPZ_DICDI  (Q76NU3), 
TCPZ_HUMAN  (P40227), TCPZ_MOUSE  (P80317), TCPZ_PIG(Q29236), 
TCPZ_PONAB  (Q5RCD2), TCPZ_RABIT  (O77622), TCPZ_SCHPO  (O94515), 
TCPZ_YEAST  (P39079), THS1_HALVD  (O30561), THS2_HALVD  (O30560), 
THS3_HALVD  (Q9HHA2), THSA_AERPE  (Q9YDK6), THSA_ARCFU  (O28045), 
THSA_HALSA  (Q9HN70), THSA_METTH  (O26320), THSA_SACS2  (Q9V2S9), 
THSA_SACSH  (P46219), THSA_SULAC  (Q9V2T5), THSA_SULTO  (O24734), 
THSA_THEAC  (P48424), THSA_THEK1  (P61112), THSA_THEK8  (O24731), 
THSA_THEKO  (P61111), THSB_AERPE  (Q9YA66), THSB_ARCFU  (O28821), 
THSB_DESMO  (Q9V2T3), THSB_HALSA  (Q9HNI0), THSB_METTH  (O26885), 
THSB_SACS2  (Q9V2T8), THSB_SACSH  (P28488), THSB_SULAC  (Q9V2T4), 
THSB_SULTO  (O24735), THSB_THEAC  (P48425), THSB_THEK1  (O24730), 
THSB_THEK8  (O24732), THSB_THEKO  (Q52500), THS_DESSY   (Q53546), 
THS_METJA   (Q58405), THS_METKA   (P50016), THS_METTL   (O93624), 
THS_PYRAB   (Q9V2Q7), THS_PYRHO   (O57762)
» more

UniProtKB/Swiss-Prot
False negative sequences		 9 sequences 

TCPG_THAWE  (Q9LKI7), TCPQL_HUMAN (A6NM43), TCPQM_HUMAN (Q96SF2), 

TCPQ_CAEBR  (A8X6I9), TCPQ_CAEEL  (Q9N358), TCPQ_CANAX  (P47828), 
TCPQ_SCHPO  (P78921), THSG_SACS2  (Q9V2T7), THSG_SACSH  (Q9HH21)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

TCPA_AMBME  (P50157), TCPA_MESAU  (P86208)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			12 sequences
			


			
BGLL_ASPFC  (B0YB65), BGLL_ASPFU  (Q4WGT3), BGLL_NEOFI  (A1DCV5), 

			
FLOA_LISIN  (Q7AP31), FLOA_LISMF  (Q723S2), FLOA_LISMO  (Q92EP8), 
MPE1_YEAST  (P35728), NAL14_HUMAN (Q86W24), PRA11_HUMAN (O60813), 
RLMKL_PSEF5 (Q4KFI6), RLMKL_PSEPF (Q3KFC5), SAT_CHLCH   (Q3AQ83)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			93 PDB
			


			pdb_00001a6d; pdb_00001a6e; pdb_00001q2v; pdb_00001q3q; pdb_00001q3r; pdb_00001q3s; pdb_00003iyg; pdb_00003ktt; pdb_00004a0o; pdb_00004a0v; pdb_00004a0w; pdb_00004a13; 
			
				pdb_00004b2t; pdb_00004v81; pdb_00004v8r; pdb_00004v94; pdb_00004xcd; pdb_00004xcg; pdb_00004xci; pdb_00005gw4; pdb_00005gw5; pdb_00005uyx; pdb_00005uyz; pdb_00006krd; 
				pdb_00006kre; pdb_00006ks6; pdb_00006ks7; pdb_00006ks8; pdb_00006nr8; pdb_00006nr9; pdb_00006nra; pdb_00006nrb; pdb_00006nrc; pdb_00006nrd; pdb_00006qb8; pdb_00006xhi; 
				pdb_00006xhj; pdb_00007lum; pdb_00007lup; pdb_00007nvl; pdb_00007nvm; pdb_00007nvn; pdb_00007nvo; pdb_00007trg; pdb_00007ttn; pdb_00007ttt; pdb_00007tub; pdb_00007wu7; 
				pdb_00007wz3; pdb_00007x0a; pdb_00007x0s; pdb_00007x0v; pdb_00007x3j; pdb_00007x3u; pdb_00007x6q; pdb_00007x7y; pdb_00007ylu; pdb_00007ylv; pdb_00007ylw; pdb_00007ylx; 
				pdb_00007yly; pdb_00008ajm; pdb_00008ajo; pdb_00008hki; pdb_00008i1u; pdb_00008i6j; pdb_00008i9q; pdb_00008i9u; pdb_00008ib8; pdb_00008sfe; pdb_00008sff; pdb_00008sg8; 
				pdb_00008sg9; pdb_00008sgc; pdb_00008sgl; pdb_00008sgq; pdb_00008sh9; pdb_00008sha; pdb_00008shd; pdb_00008she; pdb_00008shf; pdb_00008shg; pdb_00008shl; pdb_00008shn; 
				pdb_00008sho; pdb_00008shp; pdb_00008shq; pdb_00008sht; pdb_00009cr2; pdb_00009cs3; pdb_00009cs4; pdb_00009cs6; pdb_00009csa
			
			

			» more