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PROSITE entry PS50176


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50176
Entry name [info] ARM_REPEAT
Accession [info] PS50176
Entry type [info] MATRIX
Date [info] 01-DEC-2001 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50176
Associated ProRule [info] PRU00259

Name and characterization of the entry

Description [info] Armadillo/plakoglobin ARM repeat profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=45;
/DISJOINT: DEFINITION=PROTECT; N1=5; N2=41;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.4374000; R2=0.0350000; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1266.6010742; R2=2.3988764; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=231; H_SCORE=1821; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=174; H_SCORE=1684; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=*; E1=-30; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 661 in 205 different sequences
Number of true positive hits 655 in 199 different sequences
Number of 'unknown' hits 1
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 106
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.24 %
Recall (true positives / (true positives + false negatives)) 86.07 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 9
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] REPEAT
Feature description [info] ARM
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
199 sequences

AARA_DICDI  (Q54I71), ABAP1_ARATH (B7U179), ADLO1_ARATH (O22161), 
» more

UniProtKB/Swiss-Prot
False negative sequences
106 sequences

APCL_HUMAN  (O95996), APCL_MOUSE  (Q9Z1K7), APC_XENLA   (P70039), 
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

VATH_DICDI  (Q8MML6)

		
UniProtKB/Swiss-Prot
False positive sequences
5 sequences

CHAO_DROME  (P12024), DOHH_SCHPO  (Q9P6K9), FLII_BACSU  (P23445), 
» more

PDB
[Detailed view]
301 PDB

1BK5; 1BK6; 1EE4; 1EE5; 1EJL; 1EJY; 1G3J; 1I7W; 1I7X; 1IAL; 1IQ1; 1JDH;
» more