PROSITE logo

ProRule PRU00381


General rule information [?]

Accession PRU00381
Dates 6-JAN-2005 (Created)
27-JUN-2022 (Last updated, Version 12)
Data class Domain;
Predictors PROSITE; PS51057; PAIRED_2
Name Paired DNA-binding domain
Function The paired domain is a ~126 amino acid DNA-binding domain, which is found in eukaryotic transcription regulatory proteins involved in embryogenesis.
Scope(s) Eukaryota
Metazoa
Example(s) P63016 (PAX6_RAT);

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONNucleus.

Keywords [?]


Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0005634; Cellular component:nucleus
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Cross-references [?]

PROSITE PS00034; PAIRED_1; 1;

Features [?]

From: PS51057
Key From To Description Tag Condition FTGroup
DNA_BIND from to /note="Paired #"
REGION 4 60 /note="PAI subdomain #"
REGION 79 to /note="RED subdomain #"

Additional information [?]

Size range 120-140 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



View rule in raw text format (no links)

UniProtKB rule member sequences [?]