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annotation rule: PRU00297

General rule information [?]

Accession PRU00297
Dates 12-DEC-2003 (Created)
6-JUN-2017 (Last updated, Version 30)
Data class Domain
Predictors PROSITE; PS50873; PEROXIDASE_4
Name Plant heme peroxidase
Function Removal of H(2)O(2), oxidation of toxic reductants

Propagated annotation [?]

Comments [?]

case <FTGroup:1> and <FTGroup:2> and <FTGroup:3> and <FTTag:viacarbo>
Function Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Catalytic activity Donor + H(2)O(2) = oxidized donor + 2 H(2)O.
Cofactor heme b
Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
Note: Binds 2 calcium ions per subunit.
Subcellular location Secreted.
Similarity Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
end case

Cross-references [?]

case <Feature:PS50873:168=H>
end case

case <Feature:PS50873:42=H>
end case

Gene Ontology [?]

case <FTGroup:1> and <FTGroup:2> and <FTGroup:3> and <FTTag:viacarbo>
GO:0016491; Molecular function: oxidoreductase activity.
GO:0004601; Molecular function: peroxidase activity.
GO:0009055; Molecular function: electron carrier activity.
GO:0055114; Biological process: oxidation-reduction process.
GO:0006979; Biological process: response to oxidative stress.
GO:0042744; Biological process: hydrogen peroxide catabolic process.

Keywords [?]

end case

Gene Ontology [?]

case <Feature:PS50873:168=H>
GO:0020037; Molecular function: heme binding.
GO:0005506; Molecular function: iron ion binding.

Keywords [?]

end case

case <Feature:PS50873:1=Q>
end case

Gene Ontology [?]

case <FTGroup:1> or <FTGroup:2>
GO:0005509; Molecular function: calcium ion binding.

Keywords [?]

end case

case <Feature:PS50873:168=H> or <FTGroup:1> or <FTGroup:2>
end case

case <FTTag:disulf>
end case

Features [?]

From: PS50873
Key     From     To       Description   Tag   Condition   FTGroup
METAL     43     43       Calcium #1     [DE]   1
METAL     46     46       Calcium #1; via carbonyl oxygen     [VI]   1
METAL     48     48       Calcium #1; via carbonyl oxygen     G   1
METAL     50     50       Calcium #1     [DE]   1
METAL     52     52       Calcium #1     [ST]   1
METAL     169     169       Calcium #2     [TS]   2
METAL     222     222       Calcium #2     [DE]   2
METAL     225     225       Calcium #2     [TS]   2
METAL     230     230       Calcium #2     [DE]   2
SITE     38     38       Transition state stabilizer     R   3
ACT_SITE     42     42       Proton acceptor     H   3
METAL     168     168       Iron (heme axial ligand)     H   3
DISULFID     11     90           disulf   C-x*-C  
DISULFID     44     49           disulf   C-x*-C  
DISULFID     96     298           disulf   C-x*-C  
DISULFID     175     207           disulf   C-x*-C  
MOD_RES     1     1       Pyrrolidone carboxylic acid     Q  
case <FTTag:viacarbo>
BINDING     138     138       Substrate; via carbonyl oxygen     P  
end case

Additional information [?]

Size range 250-384 amino acids
Related rules None
Repeats 1
Topology Undefined
Examples P0DI10 (PER1_ARATH); Q67Z07 (PER2_ARATH): [Recover all]
Scope Eukaryota


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UniProtKB rule member sequences [?]