To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
annotation rule: PRU00316

General rule information [?]

Accession PRU00316
Dates 22-JAN-2004 (Created)
16-DEC-2016 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS50853; FN3
Name FN3 domain
Function The FN3 domain has been shown to be involved in binding substrate.

Propagated annotation [?]

Features [?]

From: PS50853
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Fibronectin type-III #        

Additional information [?]

Size range 78-135 amino acids
Related rules None
Repeats 33
Topology Not cytoplasmic
Example P23352 (KALM_HUMAN)
Scope Eukaryota; Metazoa


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to or see: prosite_license.html.

UniProtKB rule member sequences [?]