To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
annotation rule: PRU00409

General rule information [?]

Accession PRU00409
Dates 3-MAR-2005 (Created)
16-DEC-2016 (Last updated, Version 21)
Data class Domain
Predictors PROSITE; PS50975; ATP_GRASP
Name ATP-grasp domain
Function The ATP-grasp superfamily currently includes 17 groups of enzymes, catalyzing ATP-dependent ligation of a carboxylate containing molecule to an amino or thiol group-containing molecule.

Propagated annotation [?]


Comments [?]

case <FTGroup:1> or <FTGroup:2>
Cofactor Mg(2+)
Mn(2+)
Note: Binds #(magnesium or manganese,ion) per subunit.
end case


Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0000166; Molecular function: nucleotide binding.
case <FTGroup:1> or <FTGroup:2>
GO:0000287; Molecular function: magnesium ion binding.
GO:0030145; Molecular function: manganese ion binding.
end case


Keywords [?]

case <FTGroup:1> or <FTGroup:2>
end case


Features [?]

From: PS50975
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       ATP-grasp #        
case not <Triggered>
NP_BIND     27     84       ATP        
end case

METAL     152     152       Magnesium or manganese #1     [QDE]   1
METAL     165     165       Magnesium or manganese #1     E   1
METAL     165     165       Magnesium or manganese #2     E   2
METAL     167     167       Magnesium or manganese #2     N   2

Additional information [?]

case not <FTGroup:1> or not <FTGroup:2>
Warning one magnesium or manganese binding site was not detected!
end case

Size range 140-255 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q75D66 (CARB_ASHGO)
Scope Eukaryota
Bacteria
Archaea

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]