annotation rule: PRU00422

General rule information [?]

Accession PRU00422
Dates 6-APR-2005 (Created)
16-DEC-2016 (Last updated, Version 16)
Data class Domain
Predictors PROSITE; PS51099; PTS_EIIB_TYPE_2
Name PTS EIIB type-2 domain
Function Phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system.

Propagated annotation [?]


Description [?]

case (<OC:Bacteria> or <OC:Archaea>) and <Feature:PS51099:8=C>
+ RecName: EC=2.7.1.-;

Comments [?]

Domain The PTS EIIB type-2 domain is phosphorylated by phospho-EIIA on a cysteinyl residue. Then, it transfers the phosphoryl group to the sugar substrate concomitantly with the sugar uptake processed by the PTS EIIC type-2 domain.
end case


Gene Ontology [?]

case (<OC:Bacteria> or <OC:Archaea>) and <Feature:PS51099:8=C>
GO:0016740; Molecular function: transferase activity.

Keywords [?]

end case


Features [?]

From: PS51099
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       PTS EIIB type-2 #        
MOD_RES     8     8       Phosphocysteine; by EIIA     C  

Additional information [?]

Warning This domain can be found in other kind of proteins, mainly transcriptional regulators, in these cases it may serve as a regulatory function, through its phosphorylation activity, or as a simple phosphoryl. Check DE, KW, CC, FT DOMAIN AND CC CATALYTIC ACTIVITY.
Size range 98 amino acids
Related rules none
Repeats 1-2
Topology Undefined
Example P20966 (PTFBC_ECOLI)
Scope Bacteria
Archaea

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]