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annotation rule: PRU00521

General rule information [?]

Accession PRU00521
Dates 15-DEC-2005 (Created)
7-JAN-2017 (Last updated, Version 7)
Data class Domain
Predictors PROSITE; PS50262; G_PROTEIN_RECEP_F1_2
Name G-protein coupled receptors family 1
Function transduces extracellular signals by interaction with guanine nucleotide-binding (G) proteins.

Propagated annotation [?]

Comments [?]

Similarity Belongs to the G-protein coupled receptor 1 family.

Cross-references [?]


Gene Ontology [?]

GO:0004930; Molecular function: G-protein coupled receptor activity.
GO:0007186; Molecular function: G-protein coupled receptor signaling pathway.
GO:0004871; Molecular function: signal transducer activity.
GO:0007165; Biological process: signal transduction.

Keywords [?]

case <FTTag:disulf>
end case

Features [?]

From: PS50262
Key     From     To       Description   Tag   Condition   FTGroup
DISULFID     57     136           disulf   C-x*-C  
DISULFID     129     135           disulf   C-x*-C  

Additional information [?]

Size range 200-400 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q9N298 (5HT1A_PANTR)
Scope Eukaryota


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to or see: prosite_license.html.

UniProtKB rule member sequences [?]