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annotation rule: PRU00691

General rule information [?]

Accession PRU00691
Dates 5-MAR-2010 (Created)
16-DEC-2016 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS51352; THIOREDOXIN_2
Name thioredoxin domain
Function The thioredoxin domain participate in various redox reactions via the reversible oxidation of an active center disulfide bond.

Propagated annotation [?]

Gene Ontology [?]

GO:0045454; Biological process: cell redox homeostasis.

Keywords [?]

case <FTTag:disulf>
end case

Features [?]

From: PS51352
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Thioredoxin #        
DISULFID     42     45       Redox-active   disulf   C-x*-C  

Additional information [?]

Size range 100-200 amino acids
Related rules None
Repeats 1-4
Topology Undefined
Scope Eukaryota
Viruses; dsDNA viruses, no RNA stage


PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to or see: prosite_license.html.

UniProtKB rule member sequences [?]