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ProRule PRU01048


General rule information [?]

Accession PRU01048
Dates 1-APR-2014 (Created)
19-NOV-2022 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS51711; G_FEOB
Name FeoB-type guanine nucleotide-binding (G) domain
Function FeoB is involved in the uptake of ferrous iron (Fe(2+)), an important cofactor in biological electron transfer and catalysis.
Scope(s) Bacteria
Archaea
Methanocaldococcus
Example(s) P33650 (FEOB_ECOLI);

Propagated annotation [?]

Comments [?]

SIMILARITYBelongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.

Keywords [?]

case <FTGroup:1>
GTP-binding
Nucleotide-binding
end case
case <FTGroup:2>
Magnesium
Metal-binding
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0005525; Molecular function:GTP binding
GO:0003924; Molecular function:GTPase activity
end case
case <FTGroup:2>
GO:0046872; Molecular function:metal ion binding
GO:0000287; Molecular function:magnesium ion binding
end case

Features [?]

From: PS51711
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="FeoB-type G #"
BINDING 8 15 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
/ligand_label="#"		 G-x(4)-G-K-[ST] 1
BINDING 33 37 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
/ligand_label="#"		 x(2)-[ST]-x(2) 1
BINDING 54 57 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
/ligand_label="#"		 D-x(2)-G 1
BINDING 114 117 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"		 N-x(2)-D 1
BINDING 143 145 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"		 1
BINDING 15 15 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"		 [ST] 2
BINDING 35 35 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"		 [ST] 2

Additional information [?]

Size range 151-177 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



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UniProtKB rule member sequences [?]