PROSITE documentation PDOC00831
Ribosomal protein L7Ae signature


A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of:

  • Vertebrate L7A (SURF3) [1].
  • Plant L7A.
  • Yeast L7A (YL5) (Rp6).
  • Yeast protein NHP2 [2].
  • Yeast hypothetical protein YEL026w.
  • Bacillus subtilis hypothetical protein ylxQ.
  • Halobacterium marismortui Hs6.
  • Methanococcus jannaschii MJ1203.

These proteins have 100 to 265 amino-acid residues. As a signature pattern, we selected a conserved region located in the central section.

Last update:

December 2004 / Pattern and text revised.


Technical section

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_L7AE, PS01082; Ribosomal protein L7Ae signature  (PATTERN)


1AuthorsColombo P. Yon J. Garson K. Fried M.
TitleConservation of the organization of five tightly clustered genes over 600 million years of divergent evolution.
SourceProc. Natl. Acad. Sci. U.S.A. 89:6358-6362(1992).
PubMed ID1631131

2AuthorsKolodrubetz D. Burgum A.
TitleSequence and genetic analysis of NHP2: a moderately abundant high mobility group-like nuclear protein with an essential function in Saccharomyces cerevisiae.
SourceYeast 7:79-90(1991).
PubMed ID2063628

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