We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC00836TatD deoxyribonuclease family
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PURL: https://purl.expasy.org/prosite/documentation/PDOC00836
Description
The Escherichia coli protein tatD is a cytoplasmic protein with magnesium-dependent DNase activity [1]. It is similar to a number of proteins in all three kingdoms of life, among which:
- Yeast chromosome II hypothetical protein YBL055c.
- Escherichia coli hypothetical protein ycfH and HI0454, the corresponding Haemophilus influenzae protein.
- Escherichia coli hypothetical protein yjjV and HI0081, the corresponding Haemophilus influenzae protein.
- Bacillus subtilis hypothetical protein yabD.
- Haemophilus influenzae hypothetical protein HI1664.
- Mycoplasma genitalium hypothetical protein MG009.
These are proteins of from 24 to 47 Kd which contain a number of conserved regions. They can be picked up in the database by the following patterns.
Last update:December 2004 / Pattern and text revised.
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Technical section
PROSITE methods (with tools and information) covered by this documentation:
Reference
| 1 | Authors | Wexler M. Sargent F. Jack R.L. Stanley N.R. Bogsch E.G. Robinson C. Berks B.C. Palmer T. |
| Title | TatD is a cytoplasmic protein with DNase activity. No requirement for TatD family proteins in sec-independent protein export. | |
| Source | J. Biol. Chem. 275:16717-16722(2000). | |
| PubMed ID | 10747959 | |
| DOI | 10.1074/jbc.M000800200; |
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