We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC00901Ribosomal protein L21e signature
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PURL: https://purl.expasy.org/prosite/documentation/PDOC00901
Description
A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of:
- Mammalian L21 [1].
- Entamoeba histolytica L21 [2].
- Caenorhabditis elegans L21 (C14B9.7).
- Yeast L21E (URP1) [3].
- Halobacterium marismortui HL31 [4].
These proteins have 160 (eukaryotes) or 95 (archebacteria) amino-acid residues. As a signature pattern, we selected a conserved region in the central part of these proteins.
Last update:April 2006 / Pattern revised.
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Technical section
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References
| 1 | Authors | Devi K.R.G. Chan Y.-L. Wool I.G. |
| Title | The primary structure of rat ribosomal protein L21. | |
| Source | Biochem. Biophys. Res. Commun. 162:364-370(1989). | |
| PubMed ID | 2751657 |
| 2 | Authors | Petter R. Rozenblatt S. Nuchamowitz Y. Mirelman D. |
| Title | Linkage between actin and ribosomal protein L21 genes in Entamoeba histolytica. | |
| Source | Mol. Biochem. Parasitol. 56:329-333(1992). | |
| PubMed ID | 1484554 |
| 3 | Authors | Jank B. Waldherr M. Schweyen R.J. |
| Title | Yeast single copy gene URP1 is a homolog of rat ribosomal protein gene L21. | |
| Source | Curr. Genet. 23:15-18(1993). | |
| PubMed ID | 8428379 |
| 4 | Authors | Hatakeyama T. Kimura M. |
| Title | Complete amino acid sequences of the ribosomal proteins L25, L29 and L31 from the archaebacterium Halobacterium marismortui. | |
| Source | Eur. J. Biochem. 172:703-711(1988). | |
| PubMed ID | 3350019 |
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