We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
PROSITE documentation PDOC00915Ribosomal protein S12e signature
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PURL: https://purl.expasy.org/prosite/documentation/PDOC00915
Description
A number of eukaryotic ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of:
- Vertebrate S12 [1].
- Trypanosoma brucei S12 [2].
- Caenorhabditis elegans S12 (F54E7.2).
- Drosophila S12.
- Fungi S12.
These proteins have 130 to 150 amino acids. As a signature pattern, we selected a conserved region in the N-terminal part of these proteins.
Last update:December 2001 / Pattern and text revised.
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Technical section
PROSITE method (with tools and information) covered by this documentation:
References
| 1 | Authors | Lin A. Chan Y.-L. Jones R. Wool I.G. |
| Title | The primary structure of rat ribosomal protein S12. The relationship of rat S12 to other ribosomal proteins and a correlation of the amino acid sequences of rat and yeast ribosomal proteins. | |
| Source | J. Biol. Chem. 262:14343-14351(1987). | |
| PubMed ID | 3308890 |
| 2 | Authors | Marchal C. Ismaili N. Pays E. |
| Title | A ribosomal S12-like gene of Trypanosoma brucei. | |
| Source | Mol. Biochem. Parasitol. 57:331-334(1993). | |
| PubMed ID | 8433721 |
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