PROSITE documentation PDOC00915
Ribosomal protein S12e signature


A number of eukaryotic ribosomal proteins can be grouped on the basis of sequence similarities. One of these families consists of:

  • Vertebrate S12 [1].
  • Trypanosoma brucei S12 [2].
  • Caenorhabditis elegans S12 (F54E7.2).
  • Drosophila S12.
  • Fungi S12.

These proteins have 130 to 150 amino acids. As a signature pattern, we selected a conserved region in the N-terminal part of these proteins.

Last update:

December 2001 / Pattern and text revised.


Technical section

PROSITE method (with tools and information) covered by this documentation:

RIBOSOMAL_S12E, PS01189; Ribosomal protein S12e signature  (PATTERN)


1AuthorsLin A. Chan Y.-L. Jones R. Wool I.G.
TitleThe primary structure of rat ribosomal protein S12. The relationship of rat S12 to other ribosomal proteins and a correlation of the amino acid sequences of rat and yeast ribosomal proteins.
SourceJ. Biol. Chem. 262:14343-14351(1987).
PubMed ID3308890

2AuthorsMarchal C. Ismaili N. Pays E.
TitleA ribosomal S12-like gene of Trypanosoma brucei.
SourceMol. Biochem. Parasitol. 57:331-334(1993).
PubMed ID8433721

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